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Molecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Design and Synthesis of Novel Energetic Compounds, 2nd Edition
edited by
submission deadline 31 Jan 2027 | 1 articles | Viewed by 852 | Submission Open
Keywords: energetic compounds; molecular design; synthesis; structure; performance; sensitivity
Design and Applications of Phase Change Materials for Energy Storage and Conversion
edited by and Yinsheng Yu
submission deadline 31 Jan 2027 | 1 articles | Viewed by 750 | Submission Open
Keywords: phase change materials; materials chemistry; energy conversion and storage; thermally conductive composites; microencapsulation and interfacial engineering
(This special issue belongs to the Section Materials Chemistry)
Advanced Manufacturing and Interface Engineering for Perovskite Materials
edited by Chaoyu Xiang
submission deadline 31 Jan 2027 | 1 articles | Viewed by 719 | Submission Open
Keywords: metal halide perovskite; photovoltaics; LED; detectors and sensors
(This special issue belongs to the Section Materials Chemistry)
Advanced Chemical Analysis, Molecular Interactions and Remediation Strategies for Micro- and Nanoplastics
edited by Asli Baysal and
submission deadline 31 Jan 2027 | 1 articles | Viewed by 704 | Submission Open
Keywords: microplastics; nanoplastics; advanced chemical analysis; molecular interactions; polymer degradation; contaminant adsorption; remediation technologies; advanced oxidation processes; plastic additive leaching
Biotechnological Synthesis, Molecular Characterization, and Formulation of Next-Generation Cosmetic Actives
edited by , Andreea Loredana Vonica-Tincu and Daniela Lucia Muntean
submission deadline 31 Jan 2027 | 1 articles | Viewed by 687 | Submission Open
Keywords: biocosmetics; next-generation cosmeceuticals; microbial fermentation; skin delivery systems; green formulation chemistry; bioactive peptides; sustainable ingredients; encapsulation
(This special issue belongs to the Section Applied Chemistry)
Analysis and Application of Bioactive Compounds in Functional Foods submission deadline 31 Jan 2027 | 1 articles | Viewed by 677 | Submission Open
Keywords: nutritional bioactive compounds; non-nutritional bioactive compounds; functional foods development; food supplement; green extraction approach; new analytical methods; bioaccessibility; bioavailability
(This special issue belongs to the Section Food Chemistry)
Advances in Micro/Nanomaterials for Catalysis
edited by Juzhe Liu
submission deadline 31 Jan 2027 | 1 articles | Viewed by 661 | Submission Open
Keywords: micro/nanomaterials; catalysis; diverse applications; enhanced performance; advances
(This special issue belongs to the Section Materials Chemistry)
Research on 1,8-Naphthalimide Scaffold: Present and Future
edited by
submission deadline 31 Jan 2027 | 1 articles | Viewed by 652 | Submission Open
Keywords: 1,8-naphthalimide; derivative of 1,8-naphthalimide; synthesis of 1,8-naphthalimide; spectroscopic properties of 1,8-naphthalimide; fluorescent sensors; biosensors; sensing mechanisms; photophysical properties; crystal structures, computation, fluorescent dyes, cell imaging, textile dyes; OLEDs; electroluminescent materials; liquid crystal displays; ligand; intercalators; biomedical applications (analgesics); anti-depressants; anti-tumor agents; antiprotozoals; antirheumatics; antimicrobials; antivirals; anti-inflammatory agents; enzyme inhibitors
(This special issue belongs to the Section Organic Chemistry)
Bioactive Compounds and Antioxidant Activity of Extracts from Natural Plants, 3rd Edition submission deadline 31 Jan 2027 | 1 articles | Viewed by 598 | Submission Open
Keywords: bioactive compounds; natural plant products; antioxidant activity; extraction methods; polyphenols; flavonoids
(This special issue belongs to the Section Natural Products Chemistry)
Nutritional and Bioactive Components of Edible Parts of Medicinal Plants2nd Edition
edited by , Joanna Milala and
submission deadline 31 Jan 2027 | 1 articles | Viewed by 594 | Submission Open
Keywords: dietary fiber; polyphenols; ellagitannins; antioxidants; anticancer; minerals; gastrointestinal track; vitamins; phycomponents
(This special issue belongs to the Section Food Chemistry)
Innovations in Heterocyclic Chemistry: Synthesis, Characterization and Bioactivity
edited by Fernanda da Costa Santos Boechat, Maria Cecília B. V. De Souza, and
submission deadline 31 Jan 2027 | Viewed by 587 | Submission Open
Keywords: heterocycles; synthesis; bioactivity; medicinal chemistry; structure-activity relationship (SAR); green chemistry; biochromatography; sustainability
(This special issue belongs to the Section Medicinal Chemistry)
Organosulfur Compounds
edited by
submission deadline 31 Jan 2027 | 2 articles | Viewed by 557 | Submission Open
Keywords: organosulfur compounds; sulfur chemistry; asymmetric synthesis; stereoselective transformations; sulfur-containing heterocycles; catalytic sulfur functionalization; green synthesis; medicinal chemistry; biologically active sulfur compounds; sulfur-based reagents; organic synthesis; sustainable chemistry
(This special issue belongs to the Section Organic Chemistry)
Advanced Catalysts for Environmental Pollutant Degradation and Remediation
edited by
submission deadline 31 Jan 2027 | 1 articles | Viewed by 556 | Submission Open
Keywords: environmental pollutants; catalytic degradation; environmental remediation; catalytic materials; photocatalysis; advanced oxidation processes
(This special issue belongs to the Section Green Chemistry)
Studies in Polymer Degradation
edited by , Edcleide Maria Araujo and Bastos Y. M. De Almeida
submission deadline 31 Jan 2027 | Viewed by 479 | Submission Open
Keywords: degradation mechanisms; photooxidation; thermal degradation; upcycling technologies and additivities
(This special issue belongs to the Section Macromolecular Chemistry)
Biochar in Environmental Chemistry: Mechanisms, Reactivity, and Applications submission deadline 31 Jan 2027 | 1 articles | Viewed by 476 | Submission Open
Keywords: biochar; environmental chemistry; sorption mechanisms; reactivity; pollutant transformation; advanced oxidation processes; carbon sequestration; soil remediation; water treatment
(This special issue belongs to the Section Green Chemistry)
Synthesis and Application of Heteroatomic Containing Compounds
edited by
submission deadline 31 Jan 2027 | Viewed by 472 | Submission Open
Keywords: organometallic syntheses; heteroatomic asymmetry center; P-stereogenic center; asymmetric syntheses; enantioselective syntheses; transition metal complexes
(This special issue belongs to the Section Applied Chemistry)
Bioactive Compounds in Plants: Extraction and Application, 2nd Edition submission deadline 31 Jan 2027 | 1 articles | Viewed by 468 | Submission Open
Keywords: bioactive molecules; sustainable extraction; isolation and elucidation; biological activities; mechanisms of action; food science; nanotechnology; delivery systems; bioavailability; controlled release
(This special issue belongs to the Section Natural Products Chemistry)
Terpene and Phenol-Rich Natural Products: Extraction, Characterization and Biological Evaluation
edited by Sanja Matić and
submission deadline 31 Jan 2027 | Viewed by 452 | Submission Open
Keywords: terpenes; phenolic compounds; natural products; extraction techniques; structural characterization; biological activity; structure–activity relationships
(This special issue belongs to the Section Natural Products Chemistry)
Synthesis, Mechanism and Applications of Fluorinated Compounds
edited by
submission deadline 31 Jan 2027 | 1 articles | Viewed by 441 | Submission Open
Keywords: green chemistry; heterocycles; organofluorides; PFAS; per- and polyfluoroalkyl substances
(This special issue belongs to the Section Organic Chemistry)
Carbon-Based Electrochemical Materials: Advances and Applications
edited by
submission deadline 31 Jan 2027 | 1 articles | Viewed by 420 | Submission Open
Keywords: electrocatalysis; nanomaterials; HER; OER; ORR; CO2 reduction; fuel cells; single-atom catalysts; MXenes; nanostructured catalysts; sustainable energy; electrochemical conversion
(This special issue belongs to the Section Electrochemistry)
Role of High Hydrophobicity in Engineering Biomedical Coating/Surfaces: From Design to Application submission deadline 31 Jan 2027 | Viewed by 416 | Submission Open
Keywords: superhydrophobic surfaces; surface chemistry; molecular design; polymer coatings; biointerface engineering; antibacterial and anti-biofouling; green synthesis; multifunctional materials
(This special issue belongs to the Section Materials Chemistry)
Innovations in Mass Spectrometry for Analytical Chemistry
edited by Claudia S. Maier and Stanislau Stanisheuski
submission deadline 31 Jan 2027 | Viewed by 383 | Submission Open
Keywords: novel ionization techniques and ion sources; advances in mass analyzers and detectors; integration with chromatographic/electrophoretic separations; ion-mobility and other types of gas-phase separations; novel targeted and untargeted data acquisition strategies; single-cell and spatial MS; functional omics; innovations in data analysis, algorithm development, statistics, and bioinformatics
(This special issue belongs to the Section Analytical Chemistry)
Natural Products as Enzyme Inhibitors: Chemical Characterization and Bioactivity
edited by Niko Radulović and
submission deadline 31 Jan 2027 | Viewed by 380 | Submission Open
Keywords: natural products; enzyme inhibitors; chemical characterization; GC-MS; enzyme kinetics; molecular docking; QSAR; structure-activity relationships
(This special issue belongs to the Section Natural Products Chemistry)
Flavors and Fragrances in China
edited by
submission deadline 31 Jan 2027 | Viewed by 360 | Submission Open
Keywords: Chinese foods; flavor chemistry; flavor analysis; GC–MS/olfactometry; Chinese baijiu
(This special issue belongs to the Section Flavours and Fragrances)
Emerging Organic Contaminants: Advances in Detection and Removal Strategies
edited by Guodong Cao and
submission deadline 31 Jan 2027 | Viewed by 353 | Submission Open
Keywords: emerging organic contaminants; instrumental analysis; occurrence and fate; removal technologies; remediation
(This special issue belongs to the Section Applied Chemistry)
Environmental Analysis and Removal of Emerging Pollutants
edited by , and
submission deadline 31 Jan 2027 | Viewed by 335 | Submission Open
Keywords: pharmaceutical pollutants; industrial additives pollutants; analytical approaches; adsorption and photocatalytic removal processes; redox-driven degradation; bioremediation mechanisms
(This special issue belongs to the Section Green Chemistry)
Precise Design and Action Mechanism of Photocatalytic Nanomaterials
edited by
submission deadline 31 Jan 2027 | Viewed by 323 | Submission Open
Keywords: photocatalytic nanomaterials; precise design; water pollution control; molecular/atomic-level design; structure–activity relationship; microscopic action mechanism; pollution removal performance
(This special issue belongs to the Section Materials Chemistry)
Anti-Cancer and Anti-Inflammatory Activity of Natural Products
edited by
submission deadline 31 Jan 2027 | Viewed by 311 | Submission Open
Keywords: medicinal plant extracts; natural resources; phytochemicals in functional foods; marine natural products natural compounds and human health; analytical methods; novel perspectives on applications of phytochemicals in biomedicine; bioinformatics on bioactive compounds from natural products; structure–activity relationships; ai-driven data mining for research on natural products; biological activities an molecular target identification; natural products for treatment of rare diseases; natural products for mitigating the effects of tobacco smoke; natural products for mitigating the effects of air pollution; natural products for the treatment of cancer; natural products for respiratory diseases; natural products for infectious diseases; natural products against aging; ethnopharmacology; technology transfer of natural products
(This special issue belongs to the Section Natural Products Chemistry)
Exclusive Feature Papers in Analytical Chemistry, 2nd Edition submission deadline 31 Jan 2027 | Viewed by 308 | Submission Open
Keywords: analytical chemistry; instrumentation; environment and food; pharmaceutical industry; green chemistry
(This special issue belongs to the Section Analytical Chemistry)
Circular Bioeconomy Approaches to Natural Products: From Green Extraction to Bioactivity and Biomass Valorization
edited by
submission deadline 31 Jan 2027 | Viewed by 307 | Submission Open
Keywords: natural products; green extraction; bioactivity; by-products; biomass; biomass valorization
(This special issue belongs to the Section Green Chemistry)
Recent Progress in Polymeric Drug Delivery Systems
edited by Barbara Zawidlak-Węgrzyńska, and
submission deadline 31 Jan 2027 | Viewed by 288 | Submission Open
Keywords: biomaterials; biocompatibility of polymer systems; (bio)degradable and synthetic polymers in medical applications; degradation of biomaterials, stimuli-responsive polymers (e.g., pH-, enzyme-, temperature-, or light-sensitive systems); AI-driven design and optimization of drug delivery systems; sustainability in polymer synthesis, including eco-friendly and bio-based materials
(This special issue belongs to the Section Medicinal Chemistry)
Phytochemistry, Biological Activities and Nanomaterial Applications of Medicinal and Aromatic Plants submission deadline 31 Jan 2027 | Viewed by 262 | Submission Open
Keywords: medicinal and aromatic plants; phytochemicals; bioactive natural products; biological activities; antioxidant and antimicrobial activity; green synthesis of nanoparticles; plant-mediated nanoparticles; metal and metal oxide nanoparticles; nanotechnology in biomedicine
(This special issue belongs to the Section Natural Products Chemistry)
Advances in Phenolic Compounds: Isolation, Characterization, and Bioapplications
edited by Didem Deliorman Orhan and
submission deadline 31 Jan 2027 | Viewed by 261 | Submission Open
Keywords: phenolic compounds; polyphenols; natural products; bioactive compounds; green extraction; functional foods; nutraceuticals
(This special issue belongs to the Section Natural Products Chemistry)
Advanced Research on Computer-Aided Drug Design
edited by , and Özgecan Kayalar
submission deadline 31 Jan 2027 | Viewed by 259 | Submission Open
Keywords: computer-aided drug design; structure-based drug design; molecular docking; molecular dynamics simulations; virtual screening; hit-to-lead optimization; binding free energy; ADMET prediction; machine learning in drug discovery; protein–ligand interactions; mutation-driven drug resistance; computational medicinal chemistry
(This special issue belongs to the Section Medicinal Chemistry)
Design and Functionalization of Semiconductor Nanomaterials for Photocatalysis
edited by Virgínia Ferreira and
submission deadline 31 Jan 2027 | Viewed by 250 | Submission Open
Keywords: photocatalysis; semiconductor nanoparticles; nanomaterials; heterogeneous catalysis; green photo-catalytic reactions; energy conversion; photo-assisted redox processes; pollutants photodegradation
(This special issue belongs to the Section Materials Chemistry)
Current Trends and Challenges in Biosensors for Medical Applications
edited by and Qiming Chen
submission deadline 31 Jan 2027 | Viewed by 248 | Submission Open
Keywords: biosensing chemistry; molecular recognition; analytical chemistry; chemical transduction; functional materials
(This special issue belongs to the Section Applied Chemistry)
The Future of Anti-Cancer Agents Driven by High-Throughput Technologies, Computational Chemistry and Artificial Intelligence submission deadline 31 Jan 2027 | Viewed by 242 | Submission Open
Keywords: anti-cancer agents; medicinal chemistry; synthesis and SAR optimization; mechanism of action; oncogenic signaling pathways; chemoresistance; in silico modeling; targeted drug delivery
(This special issue belongs to the Section Medicinal Chemistry)
Biopolymers for Drug Delivery Systems, 2nd Edition
edited by and Petra Arany
submission deadline 31 Jan 2027 | Viewed by 233 | Submission Open
Keywords: drug delivery systems; biopolymers; personalized medication; nanoparticle; hydrogel; 3D printing
(This special issue belongs to the Section Medicinal Chemistry)
Research Progress on Functional Lipids and Their Applications in Health Food Systems—2nd Edition
edited by
submission deadline 31 Jan 2027 | Viewed by 223 | Submission Open
Keywords: lipid crystallization; lipid oxidation; enzymatic lipid modification; processing; health benefits; structured emulsions; lipid emulsions; lipid capsules
(This special issue belongs to the Section Food Chemistry)
Recent Advances of Nanomaterials in Electrochemistry
edited by Najeeb Lashari
submission deadline 31 Jan 2027 | Viewed by 222 | Submission Open
Keywords: nanomaterials; electrochemistry; nanostructured electrodes; electrocatalysis; energy storage; batteries; supercapacitors; electrochemical sensors; nanocomposites; two-dimensional materials; transition metal oxides; carbon nanomaterials; conductive polymers; interface engineering; charge transport; photoelectrochemistry; green energy technologies; surface chemistry; nano-electrocatalysts; advanced functional materials
(This special issue belongs to the Section Nanochemistry)
Phenolic Compounds from Foods: Extraction, Characterization, and Biological Activity submission deadline 31 Jan 2027 | Viewed by 216 | Submission Open
Keywords: phenolic compounds; food extracts; extraction techniques; chemical characterization; biological activity; antioxidant properties
(This special issue belongs to the Section Food Chemistry)
Chemical Characterisation and Biological Evaluation of Bioactive Extracts and Functional Ingredients from Agro-Food By-Products
edited by Anca Becze
submission deadline 31 Jan 2027 | Viewed by 208 | Submission Open
Keywords: agro-food by-products; compositional profiling; bioactive compounds; extraction and valorisation; functional food ingredients; antioxidant and antimicrobial activity
(This special issue belongs to the Section Food Chemistry)
Carbon-Based Nanomaterials and Their Applications
edited by Naveen Kumar Reddy Bogireddy, Juan Horacio Pacheco-Sánchez and Claudia Rosario Muro-Urista
submission deadline 31 Jan 2027 | Viewed by 205 | Submission Open
Keywords: carbon nanomaterials; graphene; carbon nanotubes; fullerenes; graphyne; diamond-like carbon; carbon dots; molecular dynamics; density functional theory; Monte Carlo simulation; multiscale modeling; catalysis; photocatalysis; adsorption; CO2 capture; hydrogen storage; energy storage; supercapacitors; wastewater treatment; environmental remediation; sustainable materials; nanocomposites; gas separation; porous carbon materials; green synthesis
(This special issue belongs to the Section Materials Chemistry)
Ionic Liquids and Deep Eutectic Solvents for Pharmaceutical Analysis
edited by and Branislava Teofilović
submission deadline 31 Jan 2027 | Viewed by 201 | Submission Open
Keywords: ionic liquids; deep eutectic solvents; physicochemical analysis; green extraction and separation; phytochemicals; pharmaceutical analysis; chromatographic analysis; active pharmaceutical ingredients
(This special issue belongs to the Section Analytical Chemistry)
Biologically-Derived Nanomaterials: Synthesis, Functionalization and Applications in Environmental and Circular Technologies
edited by , and
submission deadline 31 Jan 2027 | Viewed by 186 | Submission Open
Keywords: green synthesis; nanomaterials; biomass-derived materials; water treatment; environmental remediation; circular economy; photocatalysis; waste valorisation
(This special issue belongs to the Section Nanochemistry)
Emerging Natural Antioxidants for Food Storage and Functional Food Innovation submission deadline 31 Jan 2027 | Viewed by 184 | Submission Open
Keywords: natural antioxidants; food storage; functional food; food safety; shelf life
(This special issue belongs to the Section Food Chemistry)
Aromatic Heterocyclic Compounds: From Synthesis to Biological Activities Research submission deadline 31 Jan 2027 | Viewed by 182 | Submission Open
Keywords: aromatic heterocycles; organic synthesis; medicinal chemistry; bioactive scaffolds; SAR; synthetic methodologies
(This special issue belongs to the Section Organic Chemistry)
Advanced Metal-Based Drug Formulations in Cancer Treatment
edited by Sanja A. Mijatović and
submission deadline 31 Jan 2027 | Viewed by 177 | Submission Open
Keywords: metal-based drugs; chemotherapy; cancer; tumor microenvironment; hybrid molecules; drug design; anticancer activity; drug delivery; tumor resistance
(This special issue belongs to the Section Medicinal Chemistry)
Biomaterials and Bioactive Systems: From Synthesis to Biomedical Applications
edited by Pedro M.G. Nicolau, and
submission deadline 31 Jan 2027 | Viewed by 167 | Submission Open
Keywords: biomaterials; bioactive systems; tissue engineering; drug delivery; biomedical applications
(This special issue belongs to the Section Cross-Field Chemistry)
New Insights into Maillard Reaction
edited by Junjian Miao and
submission deadline 31 Jan 2027 | Viewed by 159 | Submission Open
Keywords: Maillard reaction; advanced glycation end-products (AGEs); food chemistry; flavor formation; non-enzymatic browning; acrylamide mitigation; reaction kinetics; nutritional impact; bioactive compounds; food processing
(This special issue belongs to the Section Flavours and Fragrances)
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