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Molecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Flavors and Fragrances in China
edited by
submission deadline 30 May 2026 | Viewed by 64 | Submission Open
Keywords: Chinese foods; flavor chemistry; flavor analysis; GC– MS/olfactometry; Chinese baijiu
(This special issue belongs to the Section Flavours and Fragrances)
Emerging Contaminants and Their Transformation Products in the Environment: Advanced Analytical Methods for Assessing Ecological and Human Health Impacts
edited by
submission deadline 30 May 2026 | Viewed by 59 | Submission Open
Keywords: emerging contaminants; transformation products; analytical methods; ecological impact; human health risk; contaminant fate; environmental monitoring
(This special issue belongs to the Section Analytical Chemistry)
Effect of Natural Products in the Cancer Therapy Mechanism—2nd Edition
edited by
submission deadline 30 May 2026 | Viewed by 43 | Submission Open
Keywords: anticancer activities; therapeutic potential of plants; phytochemicals; natural products; apoptosis; metastasis; angiogenesis; molecular mechanisms; alkaloids; terpenoids; polyphenols
(This special issue belongs to the Section Chemical Biology)
Advancing Polyethylene Glycol as a Green Solvent in Chemical and Engineering Applications
edited by
submission deadline 30 May 2026 | Viewed by 31 | Submission Open
Keywords: polyethylene glycol; PEGylated chemicals; fundamental research on PEG; PEG as a chemical solvent; PEG in deep eutectic solvents; PEG in mixed solvents; PEG centered applications
(This special issue belongs to the Section Molecular Liquids)
Recent Advances in Protein Crystallography Methods and Instrumentation
edited by
submission deadline 30 May 2026 | Viewed by 24 | Submission Open
Keywords: protein crystallography; advanced crystallization techniques; advanced X-ray sources; X-ray free-electron lasers (XFELs); fourth-generation high-brilliance synchrotrons; microcrystals and nanocrystals; radiation damage; time-resolved experiments; cryo-electron microscopy (cryo-EM); advanced crystallization techniques; lipid cubic phase (LCP); microseed matrix screening (MMS); langmuir– Blodgett nanotemplate (LBNT); ultrasound and microwave-assisted crystallization; electro-crystallization; controlled evaporative crystallization; nanocrystallization
(This special issue belongs to the Section Chemical Biology)
Computational Approaches in Antimicrobial and Antiviral Drug Discovery: Deciphering Drug Binding and Molecular Mechanisms
edited by , and Simone La Frazia
submission deadline 31 May 2026 | 6 articles | Viewed by 12316 | Submission Open
Keywords: molecular docking; virtual screening; molecular dynamics simulations; artificial intelligence; antimicrobial or antiviral activity; computational drug discovery; molecular mechanisms; experimental assays
(This special issue belongs to the Section Computational and Theoretical Chemistry)
Current Research Status of Metal-Organic Frameworks and Covalent Organic Frameworks
edited by Teng Zhang and Wenju Wang
submission deadline 31 May 2026 | 6 articles | Viewed by 12010 | Submission Open
Keywords: gas separation; gas storage; catalyst; chemical sensing; biological application; energy storage
(This special issue belongs to the Section Materials Chemistry)
Biologically Active Molecules: Extraction Strategies, Therapeutic Potential and Biomedical Perspective
edited by
submission deadline 31 May 2026 | 5 articles | Viewed by 7151 | Submission Open
Keywords: natural bioactive components; extraction techniques; therapeutic and biomedical profiling
(This special issue belongs to the Section Medicinal Chemistry)
New Strategies for Drug Development
edited by and Ariel Marchlewicz
submission deadline 31 May 2026 | 3 articles | Viewed by 5692 | Submission Open
Keywords: drugs; biosynthesis; biotransformation; natural products; biological activity; bioactive compounds; structure– activity relationship; drug development
(This special issue belongs to the Section Medicinal Chemistry)
Featured Review Papers in Food Chemistry—2nd Edition
edited by
submission deadline 31 May 2026 | 2 articles | Viewed by 4873 | Submission Open
Keywords: food analysis; food additives; food supplements; functional foods; physicochemical properties; agro-food wastes recycling; bioaccessibility and bioavailability; food stability; food security
(This special issue belongs to the Section Food Chemistry)
Harnessing Nature’s Chemical Diversity: Innovations in Isolation, Identification, and Synthesis
edited by Niko Radulović and
submission deadline 31 May 2026 | 3 articles | Viewed by 4695 | Submission Open
Keywords: natural product chemistry; phytochemistry and essential oils; isolation and structural elucidation; chromatographic techniques (GC; HPLC; etc.); mass spectrometry (GC-MS; LC-MS; etc.); NMR spectroscopy; analytical chemistry; synthetic and semi-synthetic methods; bioactive compounds and biological activity; medicinal and aromatic plants; chemotaxonomy; chemical ecology and plant defense mechanisms; biotechnological applications; structure– activity relationships (SAR); biomimetic synthesis
(This special issue belongs to the Section Natural Products Chemistry)
Phytochemistry, Antioxidants, and Anti-Diabetes
edited by , Gordana Rusak and
submission deadline 31 May 2026 | 2 articles | Viewed by 4183 | Submission Open
Keywords: bioactive compounds; natural antioxidants; plant extracts; functional foods; nutraceuticals; diabetes
(This special issue belongs to the Section Natural Products Chemistry)
5th Anniversary of the "Applied Chemistry" Section
edited by
submission deadline 31 May 2026 | 4 articles | Viewed by 3498 | Submission Open
Keywords: applied chemistry; new molecules and natural materials; solar energy and photo-electro-catalysis; analytical methods and techniques; electrochemistry and energy; biodegradable materials and medicines; environment and green chemistry
(This special issue belongs to the Section Applied Chemistry)
Development and Design of Novel Electrode Materials
edited by
submission deadline 31 May 2026 | 3 articles | Viewed by 3357 | Submission Open
Keywords: electrode materials; supercapacitors; batteries; electrocatalysis; photovoltaic materials
(This special issue belongs to the Section Electrochemistry)
Exclusive Feature Papers on Molecular Structure, 2nd Edition
edited by
submission deadline 31 May 2026 | 3 articles | Viewed by 3294 | Submission Open
Keywords: molecular structure; chemical bonding; molecular clusters; molecular similarity; protein structure prediction; quantum chemistry; spectroscopy; molecular dynamics simulations
(This special issue belongs to the Section Molecular Structure)
Antimicrobial Compounds and Biocontrol Strategies in Food Microbiology and Safety submission deadline 31 May 2026 | 2 articles | Viewed by 3214 | Submission Open
Keywords: antimicrobial compound; natural; synthetic; microbial; application; biocontrol; food; crop; agricultural; pathogenic; spoilage; bacteria; mold; in vitro; in vivo; mechanisms of action; membrane disruption; enzyme inhibition; interference with microbial communication; resistance management
(This special issue belongs to the Section Food Chemistry)
Feature Papers in Applied Chemistry: 4th Edition
edited by
submission deadline 31 May 2026 | 2 articles | Viewed by 2892 | Submission Open
Keywords: applied chemistry; new molecules/materials; analytical methods and techniques; electrochemistry and catalysis; new materials and medicines
(This special issue belongs to the Section Applied Chemistry)
Opportunities and Challenges in Protein Crystallography
edited by
submission deadline 31 May 2026 | 1 articles | Viewed by 2647 | Submission Open
Keywords: protein crystals; X-ray diffraction; cryo-EM; small-angle X-ray scattering; phasing methods; structural analysis
(This special issue belongs to the Section Chemical Biology)
Nanotechnology Landscape in Modern Medicine
edited by
submission deadline 31 May 2026 | 1 articles | Viewed by 2542 | Submission Open
Keywords: nanotechnology; nanomedicine; healthcare; nanomaterials and nanostructures; nanoparticles; drug delivery systems; regenerative medicine; biosensing and monitoring; imaging and dignosis
(This special issue belongs to the Section Materials Chemistry)
Challenges and Future Directions in Toxic Activity and Antimicrobial Application of Plant and Food Extracts submission deadline 31 May 2026 | 2 articles | Viewed by 2422 | Submission Open
Keywords: effectiveness: evaluate the efficacy of extracts under various conditions and against different pathogens; toxicity: investigate potential adverse effects of extracts on humans and animals; biodiversity: explore the diversity of plant species to discover new antimicrobial properties; sustainability: develop extraction and production methods that are environmentally friendly and sustainable; innovation: apply modern technologies; such as biotechnology; to improve the efficacy of extracts
(This special issue belongs to the Section Natural Products Chemistry)
Nutritional and Bioactive Components of Edible Parts of Medicinal Plants
edited by , and Joanna Milala
submission deadline 31 May 2026 | 3 articles | Viewed by 2230 | Submission Open
Keywords: herbs; dietary fiber; polyphenols; ellagitannins; antioxidants; minerals; gastrointestinal track
(This special issue belongs to the Section Food Chemistry)
Bioactive Compounds for Brain Ischemia and Neurodegenerative Disease—3rd Edition submission deadline 31 May 2026 | 1 articles | Viewed by 1890 | Submission Open
Keywords: brain; neuroprotection; neurodegenerative diseases; ischemia; mitochondria; oxidative stress; inflammation; bioactive compounds
(This special issue belongs to the Section Medicinal Chemistry)
Food Bioactive Compounds: Chemical Challenges and Opportunities, 2nd Edition submission deadline 31 May 2026 | 1 articles | Viewed by 1532 | Submission Open
Keywords: bioactive compounds; non-conventional extraction techniques; modern analytical methods; authenticity; molecular mechanism; functional properties; antimicrobial; antitumoral; anti-inflammatory; and antioxidant properties
(This special issue belongs to the Section Cross-Field Chemistry)
Advances in Biomaterials: Preparation, Properties and Applications in Biomedicine and Tissue Engineering
edited by and
submission deadline 31 May 2026 | 1 articles | Viewed by 543 | Submission Open
Keywords: biomaterials; decellularized extracellular matrix; tissue engineering; biomedicine; dECM scaffold; bioink; hydrogels
(This special issue belongs to the Section Materials Chemistry)
Innovations in Heterocyclic Chemistry: Synthesis, Characterization and Bioactivity
edited by Fernanda da Costa Santos Boechat, Maria Cecília B. V. De Souza, and
submission deadline 31 May 2026 | Viewed by 334 | Submission Open
Keywords: heterocycles; synthesis; bioactivity; medicinal chemistry; structure-activity relationship (SAR); green chemistry; biochromatography; sustainability
(This special issue belongs to the Section Medicinal Chemistry)
Lignin Valorization in Biorefineries
edited by Carlos Eduardo De Araújo Padilha, Everaldo Silvino Dos Santos and Domingos Fabiano de Santana Souza
submission deadline 31 May 2026 | Viewed by 236 | Submission Open
Keywords: pretreatment; bioactive compounds; antioxidant properties; kraft lignin; extraction; thermochemical processes
(This special issue belongs to the Section Green Chemistry)
Advanced Materials for Efficient Sulfur Removal in Industrial and Environmental Applications
edited by and Tendai O. Dembaremba
submission deadline 31 May 2026 | Viewed by 211 | Submission Open
Keywords: industrial desulfurization; catalytic sulfur removal; nanostructured catalysts; hydrodesulfurization (HDS); environmental catalysis; SOx emission control; clean fuel production; process scalability
Doping Strategies for Carbon-Based Electrocatalysts
edited by
submission deadline 31 May 2026 | Viewed by 183 | Submission Open
Keywords: carbons; p-doping; n-doping; Fermi level engineering; electrocatalysis; electrochemical sensors; energy conversion and storage; environmental remediation
(This special issue belongs to the Section Electrochemistry)
Supercritical Fluid Extraction of Natural Products submission deadline 31 May 2026 | Viewed by 157 | Submission Open
Keywords: supercritical fluid extraction (SFE); natural products; green chemistry; carbon dioxide extraction; sustainable extraction; phytochemicals; scale-up; environmentally friendly processes
(This special issue belongs to the Section Natural Products Chemistry)
Essential Oils and Their Derivatives: Characterization, Biological Activity and Application
edited by Noura Ahmed
submission deadline 31 May 2026 | Viewed by 127 | Submission Open
Keywords: essential oils; aromatic plants; natural products; bioactive compounds; biological activities; pharmacology of volatiles; structure elucidation; isolation techniques
(This special issue belongs to the Section Natural Products Chemistry)
Electrochemical Catalytic Conversion of Small Molecules submission deadline 31 May 2026 | Viewed by 122 | Submission Open
Keywords: electrocatalysis; small molecule conversion; single-atom catalysis; mechanism study; sustainable energy
(This special issue belongs to the Section Electrochemistry)
Covalent Organic Frameworks for Energy Storage
edited by Madagonda M Vadiyar
submission deadline 31 May 2026 | Viewed by 109 | Submission Open
Keywords: covalent organic frameworks; synthesis and characterization; energy storage; supercapacitors; aqueous batteries; zinc-ion batteries; charge storage mechanisms; ex situ/in situ characterizations
(This special issue belongs to the Section Materials Chemistry)
New Advances in Radiopharmaceutical Sciences, 2nd Edition
edited by
submission deadline 31 May 2026 | Viewed by 105 | Submission Open
Keywords: radiopharmacy/radiopharmaceuticals; radiochemistry; radionuclide therapy; theranostics; PET; SPECT; tadiolabeling techniques; radionuclide production; nuclear medicine
(This special issue belongs to the Section Medicinal Chemistry)
Bioactive Natural Products: The Potential Sources of New Drugs submission deadline 31 May 2026 | Viewed by 104 | Submission Open
Keywords: bioactive natural compounds; chemical characterization and optimization; bioactive natural products’ safety; cytotoxicity; bioactive natural products’ mechanisms of action; biological activities in vitro and in vivo; chronic diseases; bioactive natural product in non-communicable diseases-chronic inflammation/chronic stress/drug discovery/anticancer
(This special issue belongs to the Section Natural Products Chemistry)
Bioactive Compounds in Food: Extraction and Characterization submission deadline 31 May 2026 | Viewed by 100 | Submission Open
Keywords: bioactive compounds; food matrices; extraction techniques; green technologies; analytical characterization; structural elucidation; stability and bioavailability; functional food applications
(This special issue belongs to the Section Food Chemistry)
Advances in Efficient Conversion of Biomass Resources
edited by and
submission deadline 31 May 2026 | Viewed by 98 | Submission Open
Keywords: lignocellulose biomass; food waste; algal biomass; urban solid waste; platform compound; chemobiological valorization of biomass; biotransformation and biocatalysis; biomass pretreatment; biorefining; life cycles of biomass valorization
(This special issue belongs to the Section Green Chemistry)
Bioactive Food Compounds and Their Health Benefits submission deadline 31 May 2026 | Viewed by 98 | Submission Open
Keywords: polyphenolic compounds; bioactive compound; natural products; food safety; phytochemicals; carotenoids; LC-MS/MS techniques; HPLC-DAD-MS; fruits; vegetables; and mushrooms; antioxidant compounds; functional food; prebiotics; health benefits
(This special issue belongs to the Section Food Chemistry)
Advanced Materials for Gaseous Pollutant Removal
edited by , and Yueshuang Mao
submission deadline 31 May 2026 | Viewed by 97 | Submission Open
Keywords: gaseous pollutant removal; catalysis; adsorption; sustainable remediation; environmentally friendly materials
(This special issue belongs to the Section Materials Chemistry)
Organometallic Compounds: Design, Synthesis and Application: 2nd Edition
edited by
submission deadline 31 May 2026 | Viewed by 97 | Submission Open
Keywords: organometallic compounds; design and synthesis; transition metal complexes; catalysis; metal coordination; catalytic applications; mechanisms; organic– inorganic hybrid compounds
(This special issue belongs to the Section Organometallic Chemistry)
Treatment and Analysis of PFAS in Environmental Pollution
edited by
submission deadline 31 May 2026 | 1 articles | Viewed by 95 | Submission Open
Keywords: PFAS; total fluorine; treatment; environmental samples
(This special issue belongs to the Section Green Chemistry)
The Catalytic Conversion of Biomass
edited by
submission deadline 31 May 2026 | Viewed by 90 | Submission Open
Keywords: biomass valorization; catalysts; biocatalysis; electrochemical catalysis; industrial catalysis; renewable feedstocks; sustainable chemistry; bio-based products
(This special issue belongs to the Section Green Chemistry)
Analyses and Applications of Phenolic Compounds in Food—3rd Edition submission deadline 31 May 2026 | Viewed by 87 | Submission Open
Keywords: phenolics; extraction; identification; applications in food matrix
(This special issue belongs to the Section Food Chemistry)
Zeolites and Related Nanoporous Materials: Green Supports for Molecules
edited by
submission deadline 31 May 2026 | Viewed by 84 | Submission Open
Keywords: porous materials; zeolites; selective catalysts; zeolite-like materials; molecule selectivity
(This special issue belongs to the Section Materials Chemistry)
Corrosion Mechanisms and Protection Technologies of Metallic Materials Under Harsh Environments
edited by Baojun Dong, , Dezhi Zeng and
submission deadline 31 May 2026 | Viewed by 83 | Submission Open
Keywords: metal coating; non-metal coating; coating design and preparation; coating performance evaluation; corrosion mechanism in harsh environments
(This special issue belongs to the Section Materials Chemistry)
Molecular Crystals: Exploring Structure, Properties, and Applications
edited by
submission deadline 31 May 2026 | Viewed by 78 | Submission Open
Keywords: molecular crystals; polymorphism; crystal growth; solid-state structure– property relationships; shape-memory and self-healing crystals; elastic– plastic crystals; materials for electronics and photonics; pharmaceutical crystalline materials
(This special issue belongs to the Section Materials Chemistry)
Advances in Plant-Sourced Natural Compounds as Anticancer Agents, 2nd Edition submission deadline 31 May 2026 | Viewed by 77 | Submission Open
Keywords: medicinal plants; natural compounds; phytochemicals; antioxidant activity; anticancer activity; phytotherapy; drug discovery; drug delivery; pharmaceutical formulation
(This special issue belongs to the Section Natural Products Chemistry)
Bioactive Compounds in Food: Advanced Extraction and Characterization Methods submission deadline 31 May 2026 | Viewed by 75 | Submission Open
Keywords: bioactive compounds; food matrices; extraction methods; process optimization; green and sustainable solvents; characterization techniques; stability assessment; bioavailability; delivery systems; functional foods; nutraceuticals; composition– functionality relationships
(This special issue belongs to the Section Food Chemistry)
Innovative Catalysts and Multimodal Strategies for Water Remediation
edited by Lucyna Bilińska, and
submission deadline 31 May 2026 | Viewed by 75 | Submission Open
Keywords: nanostructured catalysts; thin-film catalysts; transition metal and carbon-based catalysts; advanced oxidation processes (AOPs); electrochemical advanced oxidation processes (EAOPs); photocatalysis; catalytic ozonation; novel catalysts for water remediation; wastewater treatment; functional material
(This special issue belongs to the Section Green Chemistry)
Small Fish Models for Molecular-Ethnopharmacology and Drug Discovery
edited by
submission deadline 31 May 2026 | Viewed by 73 | Submission Open
Keywords: bioactive compounds; chemical biology; natural product screening; omics; phytochemicals; systems pharmacology
(This special issue belongs to the Section Medicinal Chemistry)
Heterocycles: Design, Synthesis and Biological Evaluation, 4th Edition submission deadline 31 May 2026 | Viewed by 73 | Submission Open
Keywords: heterocycles; organic synthesis; drug design; biological activity; medicinal chemistry
(This special issue belongs to the Section Medicinal Chemistry)
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