Special Issue "Role of PPAR Receptors in Human Health and Disease"
Deadline for manuscript submissions: 30 November 2019
Prof. Dr. Raffaele Capasso
The research on cannabinoids and congeners is currently growing. Among the different classes of receptors related to the activity of these molecules, a great attention has been focused on the role of peroxisome proliferator-activated receptors (PPARs). The family of PPARs encompasses three distinct members named PPARα, PPARβ/δ, and PPARγ. PPARα activity is mainly implicated in the metabolism of lipids, carbohydrates, and amino acids; PPARγ is mostly involved in the regulation of adipogenesis, energy balance, and lipid biosynthesis; PPARβ/δ regulates fatty acid oxidation in skeletal and cardiac muscles. There is compelling evidence demonstrating that both natural and synthetic ligands, such as fatty acids, eicosanoids, phytanic acid, fibrates, palmitoylethanolamide, etc., can be used to regulate the expression and function of PPARs for the treatment of various human disorders. Therefore, the understanding of the molecular mechanisms and role of PPARs in nutrition and therapeutic treatment is the focus of this Special Issue.
Prof. Dr. Raffaele Capasso
Dr. Fabio Arturo Iannotti
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- PPAR receptors
- Natural and synthetic molecules
- Intracellular cascades
- PPARs and nutrition
- PPARs and health