Chemical Innovations for Cardiovascular Therapeutics
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".
Deadline for manuscript submissions: 30 June 2026 | Viewed by 21
Special Issue Editor
Special Issue Information
Dear Colleagues,
This Molecules Special Issue addresses a critical unmet need in cardiovascular medicine: the chemical innovation gap in developing next-generation therapies. While cardiovascular diseases (CVDs) remain the leading global cause of mortality, recent breakthroughs in medicinal chemistry, targeted delivery systems, and molecular profiling technologies now enable unprecedented precision in CVD drug design.
We specifically seek contributions that highlight:
- Novel chemical entities with validated cardiovascular targets (e.g., small molecules, RNA therapeutics, exosome modulators)
- Cutting-edge drug design strategies (AI-assisted molecular modeling, genoproteomic-guided discovery)
- Chemically-engineered delivery systems (nanocarriers, bioresponsive formulations)
- Molecular mechanisms with structural insights (X-ray crystallography, cryo-EM of drug-target complexes)
Why This Issue is Special:
- Chemical Focus: Unlike clinical pharmacology journals, we prioritize studies elucidating structure-activity relationships and molecular optimization of CVD agents
- Timeliness: Covers emerging chemical modalities (RNA drugs, exosome engineering) beyond traditional small molecules
Topics of Interest:
- Rational design of macrophage-targeting agents
- Chemical modulation of mitochondrial-cardiac interactions
- Structural basis of RNA drug delivery for CVD
- Synthetic approaches to exosome functionalization
Dr. Zia Shariat-Madar
Guest Editor
Manuscript Submission Information
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Keywords
- CVD
- drug therapy
- therapy targets
- inflammation
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