Novel Drugs for Anticancer Therapy

Dear Colleagues,

Synthesised compounds based on natural small molecules play an increasingly important role in the fight against cancer. Natural compounds such as alkaloids, flavonoids, terpenes, and glycosides have a broad activity spectrum against cancer cells, but their isolation and use in therapy are limited due to low availability or high production costs. In response, synthetic analogues and derivatives of these natural substances that retain their beneficial biological properties while offering improved stability, bioavailability, and the possibility of chemical modification have been developed. Some of them show promising results in chemotherapy; these include synthetic glycosides and flavonoids, which exhibit anticancer activity by inhibiting cell division, inducing apoptosis, or inhibiting angiogenesis. These compounds are vital in cancer treatment because they enable the development of more effective, more selective, and less toxic therapies. Furthermore, by modifying the structure of natural substances, it is possible to obtain new compounds with enhanced anticancer activity and diminished side effects which contribute to the development of modern cancer therapies. We invite authors currently conducting research in the area of obtaining and testing synthetic compounds based on natural components that exhibit anticancer activity to publish review or research papers in our Special Issue.

Prof. Dr. Maciej Wnuk
Guest Editor

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