Study on Secondary Metabolites of Microorganisms

Dear Colleagues,

The discovery of penicillin initiated the golden era of antibiotic discovery. Since then, microbial secondary metabolites have represented an important source of lead compounds, which are not only the main source of antibiotics, but also exhibit various biological activities including antibiotic, antifungal, anticancer, and antiviral activities, etc. Recently, many new microbial metabolites with novel chemical skeletons and biological activities have been isolated from microorganisms. This Topic mainly aims to focus on the discovery of new or bioactive microbial metabolites from bacteria, actinomycetes, and fungi. We welcome review and original research articles on new and bioactive secondary metabolites from microorganisms, including but not limited to, the following:

• The isolation and identification of bioactive metabolites from microorganisms.
• The application of novel techniques for the discovery of novel or bioactive microbial metabolites.
• The biosynthesis and biotransformation of bioactive microbial metabolites.
• The structure modification of lead compounds, aiming to improve their biological functions.

Dr. Minghua Chen
Guest Editor

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