Protein Structure and Protein-Ligand Interactions

Dear Colleagues,

The functions of proteins and peptides in living organisms are extensive. They are involved in the regulation of metabolism as enzymes, act as signal transducers and play an important role in structural support and DNA expression. They can function as both ligands (hormones or peptide drugs) and receptors. Dysfunctions of enzymes and receptors lead to multiple diseases; therefore, they are the prime targets of drugs. In order to gain knowledge of the processes in which proteins and peptides are involved, it is necessary to properly resolve their structure, understand the structure–activity relationship (SAR), study the ligand–target interactions, and properly model reaction mechanisms. There are still many challenges that scientists in this field must face in order to fully understand the role and activity of peptides and proteins. 

We cordially invite scientists working with peptides and proteins, both experimentalists and specialists in molecular modelling, to submit their work to our Special Issue titled “Protein Structure and Protein–Ligand Interactions”, and to share their findings and research results in this field.  

The aim of this Special Issue is to bring together original papers, reviews and short communications presenting the recent knowledge and advances in protein structure characterization and protein–ligand interaction studies.

Dr. Monika Staś
Dr. Jiří Kessler
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.