Special Issue "New Perspectives in Controlling the Spread of Multi-Drug Resistance Organisms (MDROs)"

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Medical Microbiology".

Deadline for manuscript submissions: 30 June 2023 | Viewed by 1129

Special Issue Editor

Infection Control Unit, French-Muslim Hospital, Avicenna, 93000 Bobigny, France
Interests: infection control; antimicrobial resistance; antimircrobial stewardship; health acquired infection; environmental contamination
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The evolution of multi-drug resistance organisms in the world and the difficulty of controlling the phenomenon must lead us to consider, evaluate, and propose alternatives to the infection control measures.

Most of the proposed control policies are based on a search for new strategies and recommendations to contact isolated patients who are identified as carriers or infected with MDRO. The recent pandemic related to COVID-19 has shown the limits of these policies and leads us to initiate a debate on new ways and means of prevention.

In this issue, we propose to address important questions that would allow us to consider MDRO control in our hospitals differently, such as:

  • What are the lessons to be drawn from the COVID-19 pandemic and the spread of MDRO?
  • Are MDRO organisms the same or different in terms of risk?
  • Are contact isolations mandatory to control the spread of MDRO?
  • Are adverse events related to contact isolation?
  • What is the role of microbiota in acquisition and clearance of MDRO?
  • Is it necessary to control the risk related to the environment? If so, when and how?
  • Is decolonisation useful? When? For what organisms? How?

Prof. Dr. Jean-Ralph Zahar
Guest Editor

Manuscript Submission Information

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Published Papers (1 paper)

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Research

Article
Molecular Characterization and Prevalence of Antimicrobial-Resistant Escherichia coli Isolates Derived from Clinical Specimens and Environmental Habitats
Microorganisms 2023, 11(6), 1399; https://doi.org/10.3390/microorganisms11061399 - 26 May 2023
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Abstract
Antibiotic-resistant bacteria (ARB) are present in wastewaters as their elimination during treatment in wastewater treatment plants (WWTPs) is often impossible. Water plays an important role in the spread of these microorganisms among humans, animals and the environment. This study aimed to assess the [...] Read more.
Antibiotic-resistant bacteria (ARB) are present in wastewaters as their elimination during treatment in wastewater treatment plants (WWTPs) is often impossible. Water plays an important role in the spread of these microorganisms among humans, animals and the environment. This study aimed to assess the antimicrobial resistance patterns, resistance genes and molecular genotypes by means of phylogenetic groups of E. coli isolates in aquatic habitats, including sewage and receiving water bodies, as well as clinical settings in the Boeotia regional district of Greece. The highest resistance rates among both environmental and clinical isolates were observed to be for penicillins, ampicillin and piperacillin. Resistance patterns related to extended spectrum β-lactamases (ESBL) production and ESBL genes were also detected in both environmental and clinical isolates. Phylogenetic group B2 was predominant in clinical settings and the second most frequent among wastewaters, whereas group A was dominant in all environmental isolates. In conclusion, the studied river water and wastewaters may serve as reservoirs of resistant E. coli isolates that pose potential threats to both human and animal health. Full article
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