Special Issue "Interactions between Intestinal Epithelial Cells and Microbes"
Deadline for manuscript submissions: 31 May 2019
Three decades ago, epithelial cells were appreciated to actively contribute to host defense through the secretion of inflammatory mediators, in fact, before the discovery of ubiquitous toll-like receptors (TLR) in mammalian cells. The discovery and expanding repertoire of TLRs then occupied the limelight in terms of the epithelial cell response to microbes through the 1990s. However, intestinal epithelial cell detection and response to microbial antigens is not limited to TLRs, as there are several other mechanism of detection, such as the FPRs, lectins, and anaphylatoxin receptors. In addition to receptors, there is compelling evidence that epithelial cells are affected by microbial metabolites. Thus, where are we now? Have we solved epithelial responsiveness to microbes? Has the advent of organoid cultures changed our understanding of these interactions? Is microbial pathogenicity defined at the level of the epithelial response? The objective of this Special Issue is to identify the frontier of this branch of innate immunity. I invite you to submit your manuscripts for this Special Issue: “Interactions between Intestinal Epithelial Cells and Microbes”. This edition will consider your preferred angle of engagement—whether on colonizing or shedding metabolites onto the epithelium, the detection of microbes and microbial products, or the consequence of these interactions on intestinal epithelial cell biology, possibly leading to inflammation or apoptosis. As Guest Editor of this Special Issue, I look forward to reviewing your submissions and, together, defining the present state of the science.
Prof. Dr. Andrew W Stadnyk
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.