Special Issue "Pathogenesis of Enterohaemorrhagic Escherichia coli"
Deadline for manuscript submissions: closed (30 September 2018)
Enterohaemorrhagic Escherichia coli (EHEC) is a major foodborne pathogen that can cause severe systemic disease, particularly in children and the elderly. EHEC virulence is associated with the production of a type III secretion system, enabling injection of bacterial effector proteins into the host cell. Around 40 effectors have been identified so far, which mediate EHEC adherence to intestinal epithelium and modulate various host cell functions, such as ion transport, epithelial permeability, and inflammation. In addition, Shiga toxins released during EHEC infection penetrate into the bloodstream and cause damage to the kidneys and the central nervous system. At present, there is no specific treatment available and a better understanding of the underlying mechanisms of EHEC pathogenesis is needed. In this special issue, I would like to invite you to submit a review or original research article related to virulence factors and mechanisms contributing to EHEC infections in humans.
This Special Issue will contain the extended and enhanced versions of selected papers presented from the 10th International Symposium on VTEC Conference (6–9 May 2018, Florence, Italy, http://www.vtec2018.org/).
Dr. Stephanie Schüller
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- virulence factors
- bacteria - host cell interactions
- host response