Recent Advances in Coxsackievirus Infections: Epidemiology, Pathogenesis and Methods for Control and Prevention

Dear Colleagues,

Coxsackieviruses (CVs) are ubiquitous and widespread single-stranded RNA viruses belonging to the Picornaviridae family and the genus Enterovirus. These viruses are mainly transmitted via the fecal–oral route and are considered a major cause of viral infection each year worldwide. Coxsackieviruses were first isolated in the late 1940s from the feces of paralyzed children living in Coxsackie (New York, USA) and were classified into CV groups A (CVA) and B (CVB) based on the nature of their pathogenicity in mice. Coxsackievirus infections are considered to be asymptomatic or to induce subclinical or mild symptoms. They are also associated with various acute and chronic pathologies (hand, foot, and mouth disease caused by CVA, chronic myocarditis, dilated cardiomyopathy, and autoimmune diseases such as type 1 diabetes T1D caused by CVB…). This Special Issue encourages researchers worldwide to present their latest research on CV epidemiology, virulence, cellular and molecular mechanisms involved in CV pathogenesis, and the new antiviral strategies to control CV infections.

We look forward to receiving your contributions to this Special Issue in the form of original research articles, review articles, and small reviews, including communications and opinions regarding all aspects of coxsackievirus molecular biology, epidemiology, diagnosis, virulence, pathogenesis, and future strategies to control these viruses including vaccines and antiviral molecules.

Prof. Dr. Jawhar Gharbi
Prof. Dr. Didier Hober
Guest Editors

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