Secondary Metabolism of Microorganisms, 3rd Edition
A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Microbial Biotechnology".
Deadline for manuscript submissions: 15 January 2025 | Viewed by 5319
Special Issue Editors
2. Departamento de Ciencias Biomédicas, Facultad de Veterinaria, Campus de Vegazana, Universidad de León, 24071 León, Spain
Interests: fungal secondary metabolism; molecular biology; biotechnology; genetic engineering; omics
Special Issues, Collections and Topics in MDPI journals
Interests: secondary metabolites; microorganisms; proteomics; plastics; actinobacteria; fungi; carotenoids; steroids; immunosuppressors; antibiotics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue is the continuation of our previous Special Issues, "Secondary Metabolism of Microorganisms" and “Secondary Metabolism of Microorganisms 2.0”.
Microbial secondary metabolism represents a very interesting research field. On the one hand, secondary metabolism is considered nonessential for microbial growth and development, but it results in the biosynthesis of an impressive array of compounds relevant for: (i) human and animal health (e.g., antibiotics, receptor antagonists and agonists, and immunosuppressants), (ii) food and feed (e.g., pigments), (iii) agriculture (e.g., pheromones and plant protectants), and (iv) farming (e.g., toxins). This industrially relevant group of compounds is produced by certain taxonomic clades of organisms such as bacteria, mainly Actinobacteria, and fungi. Since metabolite formation is usually repressed during the logarithmic phase of growth and boosted along the stationary growth phase, a regulatory fine-tuning of nutrients (e.g., phosphate and nitrogen), precursors, and energy molecules is needed. The understanding of this strictly controlled process opens the door to synthetic biology to redirect metabolic pathways, avoiding nutrient sinks and by-product generation.
On the other hand, secondary metabolism plays a significant ecological role in the communication among different microorganisms in nature. At present, mixed fermentation or co-cultivation is a trending method to study, understand, and harness microbial competition and communication when the appropriate physiological conditions are provided.
This Special Issue of Microorganisms invites researchers to contribute research articles, reviews, and opinions addressing the latest knowledge on the secondary metabolism of microorganisms, including molecular biology, omics, synthetic biology, industrial microbiology, genome editing, metabolite production, downstream processing, gene control and regulation, etc., both in fundamental research and its applications. This Special Issue is divided into three blocks: i) microbial secondary metabolites; ii) the regulation of secondary metabolism; and iii) communication between microbial communities. Manuscripts covering these areas of knowledge, and others related to microbial secondary metabolism, are of interest for this Special Issue.
Dr. Carlos García-Estrada
Dr. Carlos Barreiro
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Related Special Issue
- Secondary Metabolism of Microorganisms in Microorganisms (23 articles)