Trichomonas vaginalis and Trichomoniasis: Biomarkers and Possible Pharmacological Alternatives

Dear Colleagues,

The sexually transmitted infection caused by Trichomonas vaginalis, known as trichomoniasis, affects more than 370 million people worldwide. The virulence mechanisms of this parasite in the presence of cations in the urogenital tract, as well as its resistance to the drug treatments of choice, allow this microorganism to survive in the human urogenital tract. This infection can cause vaginitis, cervicitis, abortion and preterm birth in females and urethritis, prostatitis or infertility in males. Some recent studies indicate that T. vaginalis infection is a risk factor of prostate and cervicouterinal cancers through a persistent inflammatory reaction of epithelial cells. The mechanism of regulation of the genetic expression and the immunological response of this parasite in the host might be useful for the search for biomarkers for the diagnosis and treatment of this infection. The detection of molecules relevant to this infection during resistant trichomoniasis is highly important and detection methods include biomarkers of treatment and diagnosis of trichomoniasis. The aim of this Special Issue of Microorganisms is to present a collection of articles addressing topics with the most relevant research about the diagnosis and treatment of this infection, as well as the description of key molecules that can serve as biomarkers.

Dr. María Elizbeth Alvarez-Sánchez
Dr. Julio César Torres-Romero
Dr. Elisa Elvira Figueroa-Angulo
Guest Editors

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