Marine Bioactive Agents with Anticancer Potential: Discovery and Molecular Mechanisms

A special issue of Marine Drugs (ISSN 1660-3397). This special issue belongs to the section "Marine Pharmacology".

Deadline for manuscript submissions: 15 January 2026 | Viewed by 21

Special Issue Editor


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Guest Editor
Unidad de Investigación Biomédica en Cáncer, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México (UNAM), Coyoacán, Ciudad de México 04510, Mexico
Interests: cancer; molecular biology; biomarkers; cancer genomics; chemotherapy resistance; radioresistance; natural compounds; mutant p53; DNA repair

Special Issue Information

Dear Colleagues,

Therapeutic failure and tumor relapse are key factors in the high mortality rate of cancer, underscoring the urgent need to develop innovative strategies, including new drugs. In this context, marine natural products offer unique chemical compounds that can inspire the design and synthesis of novel anticancer agents. Their evolutionary origin in biological systems confers greater efficiency and specificity in interacting with molecular targets, presenting novel mechanisms of action and the ability to modulate diverse intracellular signaling pathways.

This Special Issue aims to attract papers of original research, systematic reviews, and meta-analysis articles based on, but not limited to, reporting recent evidence and views on highlighting the use of marine natural products as potential anticancer agents, emphasizing the diversity of their molecular targets and mechanistic effects. Submissions employing innovative scientific methods like co-cultures and 3D models are encouraged to better link in vitro and in vivo results. We also welcome investigations into synergistic combinations of marine compounds with current or experimental anticancer agents.

For this Special Issue, we invite academic and industry scientists to submit reviews and original and conceptual research articles highlighting the biological activities of known or novel marine compounds with a potential anticancer activity.

Prof. Dr. Jose Diaz-Chavez
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • anticancer agents
  • marine natural products
  • cancer
  • chemoresistance
  • tumor relapse
  • organoids
  • drug development
  • models in vitro/in vivo
  • co-cultures
  • biological activity

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Published Papers

This special issue is now open for submission.
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