Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
9.6
5.4
Journals
Marine Drugs
Special Issues
Marine-Derived Biomaterials for Tissue Regeneration
share announcement

Marine-Derived Biomaterials for Tissue Regeneration

A special issue of Marine Drugs (ISSN 1660-3397). This special issue belongs to the section "Biomaterials of Marine Origin".

Deadline for manuscript submissions: 31 May 2024 | Viewed by 4862

Special Issue Editors

Dr. Tiago H. Silva

E-Mail Website
Guest Editor
3B’s Research Group, I3Bs—Research Institute on Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, AvePark, Parque de Ciência e Tecnologia, Zona Industrial da Gandra, 4805-017 Barco, Portugal
Interests: marine biomaterials; bioinspired materials; tissue engineering; marine biotechnology; valorization of byproducts; biorefinery and circular economy; surface modification; biomedical applications
Special Issues, Collections and Topics in MDPI journals
Dr. Gabriela S. Diogo

E-Mail Website
Guest Editor
3B’s Research Group, I3Bs—Research Institute on Biomaterials, Bisodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, AvePark, Parque de Ciência e Tecnologia, Zona Industrial da Gandra, 4805-017 Guimarães, Portugal
Interests: biological and bioinspired materials; marine collagen; 3D structures for tissue engineering (TE); regenerative medicine applications

Special Issue Information

Dear Colleagues,

The processing of different materials derived from marine origin organisms has been explored in order to design of a broad range of medical applications, specifically in tissue engineering. Polymers and polysaccharides have been preferred for soft-tissue applications, while minerals like biosilicates and calcium phosphates, as well as composites, have found use in the regeneration of hard tissues. Combining materials technology and biotechnology, including advanced techniques (3D printing/bioprinting) of material processing, can be a step forward in the development of more complex and customized biomaterials and thus contribute to the booming field of personalized medicine. Another approach that is beginning to be addressed relies on the biological activities associated to some of those materials, enabling researchers to combine a structural role with a biochemical feature.

The present Special Issue aims to gather new insights on the latest advances in using marine biomass for the production of bio(functional) biomaterials, thus sitting at the interface between blue and red biotechnologies.

We invite colleagues to contribute with a research paper or review manuscript on the development of innovative blue biomaterials for use in tissue regeneration

Dr. Tiago H. Silva
Dr. Gabriela S. Diogo
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • polymers
  • polysaccharides
  • minerals
  • ceramics
  • marine biomaterials
  • customized biomaterials
  • tissue regeneration
  • collagen
  • chitin and chitosan
  • fish by-products

Published Papers (3 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

Jump to: Review

17 pages, 7478 KiB  
Article
Chemical Composition of Macroalgae Polysaccharides from Galician and Portugal Coasts: Seasonal Variations and Biological Properties
by Sónia P. Miguel, Caíque D’Angelo, Maximiano P. Ribeiro, Rogério Simões and Paula Coutinho
Mar. Drugs 2023, 21(11), 589; https://doi.org/10.3390/md21110589 - 10 Nov 2023
Cited by 1 | Viewed by 1340
Abstract
Crude polysaccharides extracted from the Codium sp. and Osmundea sp. macroalgae collected in different seasons (winter, spring and summer) from the Galician and North Portugal coasts were characterised, aiming to support their biomedical application to wound healing. An increase in polysaccharides’ sulphate content [...] Read more.
Crude polysaccharides extracted from the Codium sp. and Osmundea sp. macroalgae collected in different seasons (winter, spring and summer) from the Galician and North Portugal coasts were characterised, aiming to support their biomedical application to wound healing. An increase in polysaccharides’ sulphate content was registered from winter to summer, and higher values were obtained for Osmundea sp. In turn, the monosaccharide composition constantly changed with a decrease in glucose in Osmundea sp. from spring to winter. For Codium sp., a higher increase was noticed regarding glucose content in the Galician and Portugal coasts. Galactose was the major monosaccharide in all the samples, remaining stable in all seasons and collection sites. These results corroborate the sulphate content and antioxidant activity, since the Osmundea sp.-derived polysaccharides collected in summer exhibited higher scavenging radical ability. The biocompatibility and wound scratch assays revealed that the Osmundea sp. polysaccharide extracted from the Portugal coast in summer possessed more potential for promoting fibroblast migration. This study on seasonal variations of polysaccharides, sulphate content, monosaccharide composition and, consequently, biological properties provides practical guidance for determining the optimal season for algae harvest to standardise preparations of polysaccharides for the biomedical field. Full article
(This article belongs to the Special Issue Marine-Derived Biomaterials for Tissue Regeneration)
►▼ Show Figures

Figure 1

23 pages, 5407 KiB  
Article
Development of Bi- and Tri-Layer Nanofibrous Membranes Based on the Sulfated Polysaccharide Carrageenan for Periodontal Tissue Regeneration
by Stefanos Kikionis, Konstantina Iliou, Aikaterini G. Karra, Georgios Polychronis, Ioannis Choinopoulos, Hermis Iatrou, George Eliades, Efthymia Kitraki, Ioulia Tseti, Spiros Zinelis, Efstathia Ioannou and Vassilios Roussis
Mar. Drugs 2023, 21(11), 565; https://doi.org/10.3390/md21110565 - 28 Oct 2023
Viewed by 1427
Abstract
Periodontitis is a microbially-induced inflammation of the periodontium that is characterized by the destruction of the periodontal ligament (PDL) and alveolar bone and constitutes the principal cause of teeth loss in adults. Periodontal tissue regeneration can be achieved through guided tissue/bone regeneration (GTR/GBR) [...] Read more.
Periodontitis is a microbially-induced inflammation of the periodontium that is characterized by the destruction of the periodontal ligament (PDL) and alveolar bone and constitutes the principal cause of teeth loss in adults. Periodontal tissue regeneration can be achieved through guided tissue/bone regeneration (GTR/GBR) membranes that act as a physical barrier preventing epithelial infiltration and providing adequate time and space for PDL cells and osteoblasts to proliferate into the affected area. Electrospun nanofibrous scaffolds, simulating the natural architecture of the extracellular matrix (ECM), have attracted increasing attention in periodontal tissue engineering. Carrageenans are ideal candidates for the development of novel nanofibrous GTR/GBR membranes, since previous studies have highlighted the potential of carrageenans for bone regeneration by promoting the attachment and proliferation of osteoblasts. Herein, we report the development of bi- and tri-layer nanofibrous GTR/GBR membranes based on carrageenans and other biocompatible polymers for the regeneration of periodontal tissue. The fabricated membranes were morphologically characterized, and their thermal and mechanical properties were determined. Their periodontal tissue regeneration potential was investigated through the evaluation of cell attachment, biocompatibility, and osteogenic differentiation of human PDL cells seeded on the prepared membranes. Full article
(This article belongs to the Special Issue Marine-Derived Biomaterials for Tissue Regeneration)
►▼ Show Figures

Figure 1

Review

Jump to: Research

22 pages, 4599 KiB  
Review
Recent Advances in Marine Biomaterials Tailored and Primed for the Treatment of Damaged Soft Tissues
by Moon Sung Kang, Hyo Jung Jo, Hee Jeong Jang, Bongju Kim, Tae Gon Jung and Dong-Wook Han
Mar. Drugs 2023, 21(12), 611; https://doi.org/10.3390/md21120611 - 25 Nov 2023
Viewed by 1707
Abstract
The inherent self-repair abilities of the body often fall short when it comes to addressing injuries in soft tissues like skin, nerves, and cartilage. Tissue engineering and regenerative medicine have concentrated their research efforts on creating natural biomaterials to overcome this intrinsic healing [...] Read more.
The inherent self-repair abilities of the body often fall short when it comes to addressing injuries in soft tissues like skin, nerves, and cartilage. Tissue engineering and regenerative medicine have concentrated their research efforts on creating natural biomaterials to overcome this intrinsic healing limitation. This comprehensive review delves into the advancement of such biomaterials using substances and components sourced from marine origins. These marine-derived materials offer a sustainable alternative to traditional mammal-derived sources, harnessing their advantageous biological traits including sustainability, scalability, reduced zoonotic disease risks, and fewer religious restrictions. The use of diverse engineering methodologies, ranging from nanoparticle engineering and decellularization to 3D bioprinting and electrospinning, has been employed to fabricate scaffolds based on marine biomaterials. Additionally, this review assesses the most promising aspects in this field while acknowledging existing constraints and outlining necessary future steps for advancement. Full article
(This article belongs to the Special Issue Marine-Derived Biomaterials for Tissue Regeneration)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-3
Back to TopTop