Liposomes started to be studied for drug delivery in 1970s, taking advantage of their ability to encapsulate hydrophilic and hydrophobic drugs using biodegradable and biocompatible molecules. Nowadays, they remain one of the most promising strategies...
Milk fatty acid (FA) synthesis and enteric methanogenesis share common biochemical pathways related to rumen fermentation patterns and microbial volatile FA production. The FA profile of milk is known to correlate with methane (CH4) emissions; thus,...
Background/objectives: Plant-based meat analogues (PBMAs) are designed to mimic meat products and to be cooked under similar conditions by consumers. There have been few studies into the lipid stability of PBMAs, and no published studies have investi...
Background: Familial hypercholesterolemia (FH) is a monogenic disorder causing markedly elevated low-density lipoprotein cholesterol (LDL-C) and premature atherosclerosis. Glucose-6-phosphate dehydrogenase (G6PD) is a key enzyme in antioxidant defens...
This systematic review examines the impact of vegetable oil consumption, such as extra virgin olive, olive, soybean, palm olein, corn, and camellia seed oils, on both human and animal health, alongside factors influencing oil quality and safety. A va...
ATP citrate lyase (ACL) is a highly conserved enzyme across eukaryotes that catalyzes the generation of cytosolic acetyl-CoA from citrate—a pivotal step linking central carbon metabolism to lipid biosynthesis. In the oleaginous yeast Yarrowia l...
In the last twenty years, an increasing volume of research has characterized lipids as dynamic signaling molecules that play essential roles in various physiological and pathological processes, especially concerning chronic diseases such as cardiovas...
Background: Dyslipidaemia promotes atherosclerotic plaque formation. Plaques that are vulnerable to rupture have a higher proportion of inflammatory (M1:CD86) macrophages in their cap. Many plaque macrophages are derived from blood monocytes which ha...
It has long been recognized that elevated circulating lipid levels are among the strongest risk factors for the development of plaques within the arterial wall that are characteristic of atherosclerotic cardiovascular disease. Indeed, decades of stud...
Lipid droplets are the neutral lipid storage compartments of eukaryotic cells. Mitochondria are the main source for ATP, which is generated through oxidative phosphorylation. Thus, both organelles play essential roles in fatty acid metabolism and ene...
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