Special Issues

Life publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Sports Biomechanics, Injury, and Physiotherapy
edited by Manos Stefanakis
submission deadline 31 Jul 2026 | Viewed by 311 | Submission Open
Keywords: sports injuries; epidemiology; data-driven rehabilitation; objective assessment; injury prevention; return to play
(This special issue belongs to the Section Physiology and Pathology)
Vetinformatics-Driven Approaches to Animal Health and Disease
edited by and Rajesh Kumar Pathak
submission deadline 31 Jul 2026 | Viewed by 288 | Submission Open
Keywords: animal health; livestock disease; vetinformatics; computational genomics; RNAseq; multi-omics; drug discovery; molecular docking; molecular dynamics simulation; vaccine design; one health
(This special issue belongs to the Section Animal Science)
Genetic Regulation Mechanisms of Crop Salt–Alkali Tolerance
edited by
submission deadline 31 Jul 2026 | Viewed by 32 | Submission Open
Keywords: crops; salt tolerance; genome; transcriptome; yield traits; genetic regulation mechanisms
(This special issue belongs to the Section Plant Science)
Anti-Inflammatory and Natural Products
edited by
submission deadline 31 Jul 2026 | Viewed by 28 | Submission Open
Keywords: anti-inflammation; macrophage; mechanism study; in vivo/in vitro model; natural products; natural products-derived compound
(This special issue belongs to the Section Pharmaceutical Science)
Molecular Mechanisms and Immune Regulation in Animal Diseases
edited by
submission deadline 31 Jul 2026 | Viewed by 25 | Submission Open
Keywords: proteomics; animal diseases; mucosal immunity; biomarkers; host– pathogen interactions; immunoregulation; mass spectrometry; comparative medicine; veterinary proteomics; systems biology
(This special issue belongs to the Section Animal Science)
Multimodal AI for Genomic-Clinicopathologic Integration: From Preventive Screening to Precision Diagnosis
edited by Yen-Lin Chen
submission deadline 31 Jul 2026 | Viewed by 20 | Submission Open
Keywords: multimodal data integration; artificial intelligence in medicine; genomic and health data analysis; digital pathology and image analysis; predictive modeling and risk stratification; explainable machine learning (XAI)
(This special issue belongs to the Section Biochemistry, Biophysics and Computational Biology)
Mechanisms and Treatment of Eye and Vision Conditions
edited by Jeong-Min Hwang
submission deadline 31 Jul 2026 | Viewed by 12 | Submission Open
Keywords: mechanism; treatment; eye; vision
(This special issue belongs to the Section Medical Research)
Recent Advances in Head and Neck Disorders
edited by and Maximilian Dindelegan
submission deadline 20 Aug 2026 | Viewed by 19 | Submission Open
Keywords: molecular pathology; biomedical technology; systems biology
(This special issue belongs to the Section Medical Research)
Challenges and Innovations in Biomaterials for Tissue Engineering
edited by , Donny Hanjaya-Putra and Loan Bui
submission deadline 20 Aug 2026 | Viewed by 11 | Submission Open
Keywords: hydrogels; nanoparticles; extracellular matrix; microfluidics; bio-responsive; tissue engineering; regenerative medicine
(This special issue belongs to the Section Cell Biology and Tissue Engineering)
Oral Health and Systemic Conditions: From Biological Insights to Multidimensional Interventions submission deadline 27 Aug 2026 | Viewed by 203 | Submission Open
Keywords: oral health  ; periodontitis  ; dental care  ; tooth loss  ; oral cancer  ; facial esthetics  ; salivary biomarkers  ; systemic– oral health interactions  ; non-invasive therapies  ; clinical and epidemiological research
(This special issue belongs to the Section Medical Research)
Metabolic Eye Diseases: From Tomography to Clinical Prediction submission deadline 30 Aug 2026 | Viewed by 267 | Submission Open
Keywords: metabolic eye diseases; ophthalmic tomography and imaging biomarkers; diabetic retinopathy and systemic metabolic disorders; mitochondrial dysfunction and optic neuropathies; corneal metabolic diseases and ocular surface disorders; artificial intelligence in clinical prediction of eye diseases; metabolic pathways and retinal degeneration; translational research in metabolic ophthalmology
(This special issue belongs to the Section Physiology and Pathology)
Global Burden of Chronic Pain: Advances and Challenges in Pain Management and Clinical Practice
edited by Saba Javed and Billy Huh
submission deadline 30 Aug 2026 | Viewed by 38 | Submission Open
Keywords: chronic pain syndrome; cancer pain syndrome; neuromodulation; intrathecal pump; opioids; nerve blocks; joint injections
(This special issue belongs to the Section Medical Research)
Progress in Rehabilitation Interventions for Heart Failure
edited by , Jhonatan Betancourt-Peña, Iago Portela and Mauricio Hernández-Carrillo
submission deadline 31 Aug 2026 | Viewed by 68 | Submission Open
Keywords: heart failure; rehabilitation; exercise; interdisciplinary; telerehabilitation
(This special issue belongs to the Section Medical Research)
Molecular Pathways Shaping Head and Neck Cancer Care submission deadline 31 Aug 2026 | Viewed by 38 | Submission Open
Keywords: head and neck cancer; molecular pathways; tumor microenvironment; precision oncology; translational research
(This special issue belongs to the Section Medical Research)
Women's Health and Well-Being: A Focus on Obstetrics and Gynecologic Medicine
edited by Luca Roncati
submission deadline 30 Sep 2026 | Viewed by 70 | Submission Open
Keywords: women’ s health; gynecology; gynecopathology; preventive gynecological oncology; senology; breast cancer; cervical cancer; sexually transmitted infections; human papillomavirus; autoimmune diseases
(This special issue belongs to the Section Medical Research)
Neurorehabilitation: Technology-Driven Recovery and Functional Rewiring
edited by
submission deadline 30 Sep 2026 | Viewed by 51 | Submission Open
Keywords: cognitive-motor recovery; neuroplasticity; multidimensional assessment; post-stroke rehabilitation
(This special issue belongs to the Section Medical Research)
Molecular Underpinnings of Cancer: Pathways to Targeted Therapy submission deadline 30 Sep 2026 | Viewed by 45 | Submission Open
Keywords: signaling pathways; tumor microenvironment; cancer metabolism; biomarkers; drug resistance; precision medicine; targeted therapy
(This special issue belongs to the Section Medical Research)
Advanced Optical Imaging for Tissue and Tumour Characterization
edited by and Ana Teresa A. Amaral
submission deadline 30 Sep 2026 | Viewed by 30 | Submission Open
Keywords: optical imaging; label-free imaging; functional imaging; multimodal imaging; tissue characterization; tumour microenvironment; tumour heterogeneity; extracellular matrix; therapeutic monitoring
(This special issue belongs to the Section Medical Research)
Cognitive and Imaging Mechanisms in Neurological Disorders
edited by Foteini Christidi, and
submission deadline 30 Sep 2026 | Viewed by 26 | Submission Open
Keywords: neurological disorders; cognitive dysfunction; neuropsychological assessment; neuroimaging; structural MRI; functional MRI; multimodal neuroimaing; biomarkers; machine learning in neurology; neurorehabilitation
(This special issue belongs to the Section Medical Research)
Ocular Diseases: Mechanisms, Diagnostics, and Emerging Therapeutic Strategies
edited by Joanna Dolar-Szczasny
submission deadline 30 Sep 2026 | Viewed by 15 | Submission Open
Keywords: molecular mechanisms of eye disease; oxidative stress and inflammation; neurodegeneration in vision; ocular biomarkers; pharmacological therapies; gene therapy; stem cell and regenerative approaches; precision/personalized ophthalmology
(This special issue belongs to the Section Medical Research)
Pathology, Diagnosis, and Treatments of Airway Diseases submission deadline 1 Oct 2026 | 1 articles | Viewed by 444 | Submission Open
Keywords: airway diseases; COPD; asthma; cystic fibrosis; bronchiectasis; biomarkers; biologics; targeted; immunology; pathogenesis
(This special issue belongs to the Section Medical Research)
Innovations in Critical Care and Anesthesiology
edited by
submission deadline 2 Oct 2026 | Viewed by 75 | Submission Open
Keywords: artificial intelligence in ICU; point-of-care monitoring; enhanced recovery protocols; precision anesthesia; mechanical ventilation; organ support systems; perioperative medicine; critical care innovations
(This special issue belongs to the Section Medical Research)
Pharmacotherapy in Critical Care: Clinical Insight and Emerging Strategy
edited by
submission deadline 31 Oct 2026 | Viewed by 21 | Submission Open
Keywords: sepsis; multidrug resistance; extracorporeal treatments; intracranial hypertension; immunomodulation; organ support; precision medicine; intensive care pharmacology
(This special issue belongs to the Section Medical Research)
The 15th Anniversary of Life—New Trends in Animal Health Science
edited by
submission deadline 31 Dec 2026 | Viewed by 84 | Submission Open
Keywords: animal health science; animal disease; veterinary; animal nutrition; genetics; breeding and reproduction; One Health
(This special issue belongs to the Section Animal Science)
Pathogenesis, Biomarkers, and Treatments of Skin Diseases submission deadline 31 Dec 2026 | Viewed by 58 | Submission Open
Keywords: immune-pathogenesis; biomarkers; skin
(This special issue belongs to the Section Medical Research)
The Microbiome and Dysbiosis in Various Pathologies submission deadline 31 Dec 2026 | Viewed by 54 | Submission Open
Keywords: metabolic diseases (obesity; type 2 diabetes; insulin resistance; metabolic syndrome; etc.); cardiovascular diseases (atherosclerosis; hypertension; etc.); dermatological diseases (acne; eczema; psoriasis; rosacea); autoimmune and inflammatory diseases (rheumatoid arthritis; systemic lupus erythematosus; multiple sclerosis; Hashimoto’ s thyroiditis; etc.); digestive disorders (irritable bowel syndrome; inflammatory bowel disease: Crohn’ s disease and ulcerative colitis; celiac disease; lactose intolerance and other food intolerances; gastritis; helicobacter pylori infections; etc.); neurological and psychiatric disorders (Parkinson’ s and Alzheimer’ s disease; depression; anxiety; autism); recurrent infections and low immunity; cancer (colorectal; gastric; esophageal; hepatic; pancreatic; breast; pulmonary; etc.); biochemical; genetic and epigenetic biomarkers; computational analysis
(This special issue belongs to the Section Microbiology)
Cell Regulation and Function
edited by
submission deadline 31 Dec 2026 | Viewed by 16 | Submission Open
Keywords: cellular regulation; signal transduction; cell differentiation and apoptosis; systems biology and omicsdisease mechanisms
(This special issue belongs to the Section Cell Biology and Tissue Engineering)
Ophthalmologic Diseases: From Molecules and Molecular Mechanisms to Therapeutics
edited by and
submission deadline 30 Jun 2027 | Viewed by 32 | Submission Open
Keywords: retinal disease; corneal disease; genetic diseases; inflammatory diseases; ocular diseases; ocular drug development
(This special issue belongs to the Section Physiology and Pathology)
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