Structure, Activity, and Function of Protein Methyltransferases

Dear Colleagues,

This Life Special Issue entitled "Structure, Activity, and Function of Protein Methyltransferases” will collect reviews about individual Protein methyltransferases supplemented by some topical reviews all written by leading experts in the field. The scope covers Protein lysine methyltransferases, Protein arginine methyltransferases, but also the less abundant Protein glutamine methyltransferases, Protein histidine methyltransferases and Protein N-terminal end methyltransferases. This concept will make the special issue a very useful resource for researchers from the entire Protein methylation and Protein methyltransferase field.

The scope of the special issue includes histone methyltransferases involved chromatin regulation but also methylation of non-histone proteins. Topics to be considered in the individual enzyme reviews include structural features (domain architecture, homologs and paralogs, structure), biochemical features (mechanism, sequence specificity, product specificity, regulation, substrates), cellular features (subcellular localization, expression patterns, cellular roles and function, biological effects of substrate protein methylation, connection to cell signaling pathways, connection to chromatin regulation) as well as connection to diseases. Reviews should be closed with an outlook, open questions, and directions for future research.

We invite suggestions for manuscripts to be included in this special issue. Please contact the editors before preparing the manuscript for a pre-arrangement of the topic.

Prof. Dr. Albert Jeltsch
Dr. Arunkumar Dhayalan
Guest Editors

Manuscript Submission Information

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.