Diarrheagenic Pathogens and Gastrointestinal Infections

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Medical Research".

Deadline for manuscript submissions: closed (31 December 2021) | Viewed by 2451

Special Issue Editor


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Guest Editor
Institute of Medical Microbiology and Hygiene, Saarland University Medical Center, Homburg, Germany
Interests: clinical microbiology; diagnostic techniques; diarrheagenic bacteria; infectious diseases; intestinal protozoa; soil-transmitted helminths; tropical medicine
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Special Issue Information

Dear Colleagues,

Gastrointestinal infections caused by bacteria, parasites (helminths and intestinal protozoa). and viruses account for significant morbidity and mortality worldwide, with the highest burden still concentrated in the resource-constrained settings of tropical and subtropical countries.

While new molecular diagnostic techniques have revealed the importance of multiple co-infections in both symptomatic and asymptomatic individuals, a causal association between specific pathogens and subsequent clinical disease is often difficult to infer. Additionally, there is considerable setting-specificity with regard to the most prevalent pathogens so that tailored approaches are needed to improve diagnostic algorithms and clinical management.

Indeed, the wide range of potential pathogens calls for a combination of different diagnostic techniques, which is often difficult to implement in low-income countries. Hence, new rapid diagnostic tests and point-of-care assays hold promise to improve the diagnostic accuracy and cost-effectiveness of syndromic approaches in different clinical settings.

This Special Issue aims to address new developments in the epidemiology, clinical features, diagnostic techniques (including comparative diagnostic studies), treatment, prevention, and control of acute, persistent, and chronic infectious disorders of the gastrointestinal tract in individuals living in or returning from the tropics. Basic research on the pathogenesis of specific intestinal infections will be considered, as well as clinical, diagnostic, epidemiological, and cost-effectiveness studies assessing enteric pathogens in a variety of settings. Manuscripts addressing specific treatment and control interventions, including therapeutic trials and vaccine studies, are also of high interest.

You may choose our Joint Special Issue in Tropical Medicine and Infectious Disease.

Prof. Dr. Sören Becker
Guest Editor

Manuscript Submission Information

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Keywords

  • Acute, persistent and chronic diarrhea
  • Clinical features and diagnostic techniques
  • Digestive disorders
  • Enteric pathogens (bacteria, helminths, intestinal protozoa, viruses)
  • Epidemiology and spatial mapping
  • Gastrointestinal infections
  • Neglected tropical diseases
  • Treatment, prevention, and control

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Published Papers (1 paper)

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Review

11 pages, 321 KiB  
Review
Giardia and Cryptosporidium in Neo-Tropical Rodents and Marsupials: Is There Any Zoonotic Potential?
by Kegan Romelle Jones and Laura Tardieu
Life 2021, 11(3), 256; https://doi.org/10.3390/life11030256 - 20 Mar 2021
Cited by 2 | Viewed by 2001
Abstract
Cryptosporidiosis and giardiasis have been identified as emerging diseases in both developed and developing countries. Wildlife has been highlighted to play a major role in the spread of these diseases to humans. This review aims to highlight the research findings that relate to [...] Read more.
Cryptosporidiosis and giardiasis have been identified as emerging diseases in both developed and developing countries. Wildlife has been highlighted to play a major role in the spread of these diseases to humans. This review aims to highlight the research findings that relate to Cryptosporidium spp. and Giardia spp., with a focus on (1) parasitism of neo-tropical hystricomorphic rodents and marsupials from the genus Didelphis and (2) prevention and treatment strategies for humans and animals for the neo-tropical region. It was found that there are few studies conducted on neo-tropical rodent and marsupial species, but studies that were found illustrated the potential role these animals may play as zoonotic carriers of these two parasites for the neo-tropical region. Thus, it is recommended that further studies be done to assess the threat of protozoan parasites in neo-tropical wildlife to humans and domestic animals, and to further determine the most effective prophylaxis adapted for the unique conditions of the region. Full article
(This article belongs to the Special Issue Diarrheagenic Pathogens and Gastrointestinal Infections)
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