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Most Cited

  • Article
  • Open Access
4 Citations
3,489 Views
14 Pages

Glaucoma therapy aims at lowering intra-ocular pressure (IOP). Brinzolamide, a carbonic anhydrase inhibitor, is utilized as a second-line medication for treating ocular hypertension and primary open-angle glaucoma (POAG). The drug lowers the IOP maki...

  • Review
  • Open Access
4 Citations
14,903 Views
25 Pages

Glaucoma, the second leading cause of irreversible blindness globally, encompasses a heterogeneous group of ocular disorders characterized by the progressive degeneration of retinal ganglion cells. Pharmacotherapy remains the cornerstone of treatment...

  • Review
  • Open Access
3 Citations
6,170 Views
17 Pages

Artificial Intelligence in Glaucoma: A New Landscape of Diagnosis and Management

  • Patrick Xiang Ji,
  • Vethushan Ramalingam,
  • Michael Balas,
  • Lauren Pickel and
  • David J. Mathew

Glaucoma refers to a spectrum of progressive optic neuropathies and remains the leading cause of irreversible blindness worldwide. Its insidious onset poses serious challenges to conventional diagnostic methods and clinicians striving to detect early...

  • Review
  • Open Access
2 Citations
4,599 Views
17 Pages

The Activity of Substance P (SP) on the Corneal Epithelium

  • Jonathan Kopel,
  • Caezaan Keshvani,
  • Kelly Mitchell and
  • Ted Reid

In 1931, Von Euler and Gaddum isolated substance P (SP), an undecapeptide from the tachykinin family, from equine brain and intestine tissue extracts. Numerous types of cells, including neurons, astrocytes, microglia, epithelial, and endothelial cell...

  • Review
  • Open Access
2 Citations
3,989 Views
9 Pages

Updates on Systemic Immunomodulation in Peripheral Ulcerative Keratitis

  • Arash Maleki,
  • Tate Valerio,
  • Yasmin Massoudi,
  • Maria L. Ruggeri,
  • C. Stephen Foster and
  • Stephen D. Anesi

Peripheral ulcerative keratitis (PUK) is an inflammatory process causing thinning of the cornea, epithelial defect, and inflammatory infiltrates and is caused by several etiologies. This sight-threatening condition can indicate the presence of potent...

  • Article
  • Open Access
1 Citations
1,731 Views
6 Pages

This study aimed to find out whether three Texas state policies restricting opioid prescriptions have influenced the prescribing patterns of the oculoplastic department at the University of Texas Medical Branch (UTMB). This is a retrospective chart r...

  • Feature Paper
  • Article
  • Open Access
1 Citations
4,770 Views
9 Pages

In Vitro Anti-Inflammatory Potential of Pomegranate Extract (Pomanox®) in a Reconstituted Human Corneal Epithelium Model

  • Marcos Peñalver-Mellado,
  • Fredy Silva-Fuentes,
  • Agustín Villar,
  • Anna Mula and
  • Andrea Zangara

An in vitro study was conducted using a model of reconstituted human corneal epithelial (SkinEthic™ HCE/Human Corneal Epithelium) to test the modulation of cytokines secretion activity of Pomanox® (PMX), a standardized commercial extract of...

  • Article
  • Open Access
1 Citations
4,256 Views
10 Pages

Background: This study aims to evaluate the visual performance, both quantitative and qualitative, of the novel non-diffractive extended monofocal intraocular lens (Evolux, Sifi) following cataract surgery. This serves as a preliminary study to asses...

  • Review
  • Open Access
1 Citations
7,124 Views
15 Pages

Hereditary Optic Neuropathies: An Updated Review

  • Samuel K. Lee,
  • Caroline Mura,
  • Nicolas J. Abreu,
  • Janet C. Rucker,
  • Steven L. Galetta,
  • Laura J. Balcer and
  • Scott N. Grossman

Hereditary optic neuropathies (HONs) are a class of genetic disorders that may lead to vision loss due to either acute or progressive injury to the optic nerve. Although HONs may commonly manifest as isolated optic atrophy, these disorders can also h...

  • Review
  • Open Access
1 Citations
3,159 Views
24 Pages

Three-Dimensional Printing for Accessible and Personalized Ophthalmic Care: A Review

  • Mina Mina,
  • Ajay Kumar Goel,
  • Fady Mina,
  • Doris Goubran and
  • Nand Goel

Over 2.2 billion people across the globe face significant barriers to accessing essential ophthalmic care, with elderly, rural, and refugee populations being disproportionately affected, deepening existing disparities in eye care. Three-dimensional p...

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J. Clin. Transl. Ophthalmol. - ISSN 2813-1053