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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Clinical Updates on Rheumatoid Arthritis: 2nd Edition
edited by Francesca Bandinelli
submission deadline 30 Nov 2025 | 1 articles | Viewed by 1526 | Submission Open
Keywords: rheumatoid arthritis; rheumatology; treatment; diagnosis; biomarkers; rheumatic disease
(This special issue belongs to the Section Immunology & Rheumatology)
Rheumatoid Arthritis: Challenges, Innovations and Outcomes
edited by
submission deadline 15 Dec 2025 | 1 articles | Viewed by 1463 | Submission Open
Keywords: rheumatoid arthritis; pathogenesis; treatments; outcomes; autoimmunity
(This special issue belongs to the Section Immunology & Rheumatology)
Diagnosis and Treatment of Rheumatic Diseases
edited by Răzvan Gabriel Drăgoi and
submission deadline 20 Dec 2025 | 4 articles | Viewed by 8512 | Submission Open
Keywords: rheumatic diseases; patient-reported outcomes; assessment; arthritis; impairment; connective tissue diseases; biological and targeted synthetic therapies; impairment
(This special issue belongs to the Section Immunology & Rheumatology)
Clinical Treatment and Management of Rheumatic Diseases, Autoinflammatory Diseases, and Autoimmune Disorders
edited by Merav Lidar and
submission deadline 20 Dec 2025 | 6 articles | Viewed by 7242 | Submission Open
Keywords: rheumatic diseases; autoinflammatory diseases; autoimmune disorders; rheumatoid arthritis; diagnosis
(This special issue belongs to the Section Immunology & Rheumatology)
Autoimmune Diseases and Multisystem Inflammation: Pathophysiology and Therapeutic Strategies
edited by
submission deadline 30 Dec 2025 | 1 articles | Viewed by 1159 | Submission Open
Keywords: autoimmune diseases; cardiovascular diseases; cutaneous diseases; gastrointestinal diseases; pulmonary diseases; renal diseases; systemic manifestation; rheumatoid arthritis; systemic lupus erythematosus; vasculitis
(This special issue belongs to the Section Immunology & Rheumatology)
Clinical Advances in Antiphospholipid Syndrome (APS)
edited by
submission deadline 30 Dec 2025 | Viewed by 189 | Submission Open
Keywords: thrombosis; pregnancy; antiphospholipid syndrome; lupus anticoagulant; antiphospholipid antibodies
(This special issue belongs to the Section Immunology & Rheumatology)
Rheumatoid Arthritis: Clinical Updates on Diagnosis and Treatment
edited by
submission deadline 20 Jan 2026 | 12 articles | Viewed by 39815 | Submission Open
Keywords: rheumatoid arthritis; disease-modifying antirheumatic drugs (DMARDs); biological therapies; Janus kinase inhibitors (JAK inhibitors); treatment strategies; joint destruction; comorbidity; drug safety
(This special issue belongs to the Section Immunology & Rheumatology)
POTS, ME/CFS and Long COVID: Recent Advances and Future Direction
edited by Svetlana Blitshteyn
submission deadline 20 Jan 2026 | 2 articles | Viewed by 12310 | Submission Open
Keywords: POTS; ME/CFS; long COVID; dysautonomia; orthostatic intolerance; autoimmunity
(This special issue belongs to the Section Immunology & Rheumatology)
Clinical Advances in Autoimmune Disorders submission deadline 20 Jan 2026 | 4 articles | Viewed by 3885 | Submission Open
Keywords: systemic sclerosis; Raynaud’ s phenomenon; digital ulcers; scleroderma renal crisis; pulmonary arterial hypertension; interstitial lung disease; fibrosis
(This special issue belongs to the Section Immunology & Rheumatology)
Allergen-Specific Immunotherapy (AIT) for Allergic Diseases of the Respiratory Tract and Food Allergies
edited by
submission deadline 20 Jan 2026 | 2 articles | Viewed by 3511 | Submission Open
Keywords: allergy; allergic rhinitis; allergic conjunctivitis; allergic asthma; food allergy; peptide immunotherapy; allergoids; SLIT; SCIT; OIT
(This special issue belongs to the Section Immunology & Rheumatology)
Current and Emerging Therapies for Rheumatoid Arthritis
edited by
submission deadline 20 Jan 2026 | 1 articles | Viewed by 3218 | Submission Open
Keywords: DMARDs (disease-modifying anti-rheumatic drugs); boDMARDs (biological DMARDs); bsDMARDs (biosimilar DMARDs); csDMARDs (conventional synthetic DMARDs); rheumatoid arthritis; tsDMARDs (targeted synthetic DMARDs)
(This special issue belongs to the Section Immunology & Rheumatology)
Preventive Strategies and Novel Treatments for Rheumatoid Arthritis
edited by
submission deadline 20 Jan 2026 | Viewed by 156 | Submission Open
Keywords: rheumatoid arthritis; antibodies; biologics; JAK; environment; susceptibility; therapeutic strategies
(This special issue belongs to the Section Immunology & Rheumatology)
Systemic Lupus Erythematosus: Current Trends and Therapeutic Innovations
edited by Giuseppe Barilaro
submission deadline 15 Feb 2026 | 4 articles | Viewed by 4391 | Submission Open
Keywords: systemic lupus erythematosus; autoantibodies; biomarkers; therapeutic drugs; lupus nephritis; quality of life; new treatment strategies
(This special issue belongs to the Section Immunology & Rheumatology)
Targeted Treatment in Chronic Inflammatory Arthritis
edited by , and Simone Perniola
submission deadline 20 Feb 2026 | 4 articles | Viewed by 8331 | Submission Open
Keywords: rheumatoid arthritis; psoriatic arthritis; ankylosing spondylitis; spondyloarthritis; disease-modifying antirheumatic drugs (DMARDs); personalized medicine; immunomodulatory therapies; patient outcomes; combination therapies
(This special issue belongs to the Section Immunology & Rheumatology)
Rheumatoid Arthritis: Insights into Appropriate Diagnosis, Treatment and Management
edited by
submission deadline 20 Feb 2026 | Viewed by 128 | Submission Open
Keywords: rheumatoid arthritis; precision medicine; difficult-to-treat rheumatoid arthritis; late-onset rheumatoid arthritis; ageing society; comorbidities
(This special issue belongs to the Section Immunology & Rheumatology)
Allergic and Eosinophilic Diseases: Diagnosis, Treatment and Management (Second Edition)
edited by Aikaterini Detoraki
submission deadline 25 Feb 2026 | Viewed by 117 | Submission Open
Keywords: allergy; eosinophilic diseases; immunology; clinical immunology; asthma; diagnosis; treatment; management
(This special issue belongs to the Section Immunology & Rheumatology)
New Advances in Systemic Lupus Erythematosus (SLE)
edited by
submission deadline 20 Mar 2026 | 2 articles | Viewed by 1936 | Submission Open
Keywords: systemic lupus erythematosus; autoantibodies and biomarkers; lupus nephritis; new and novel treatments; targeted treatment or precision medicine; quality of life
(This special issue belongs to the Section Immunology & Rheumatology)
Translational Immunology in Clinical Medicine: From Preclinical Insights to Therapeutic Impact
edited by
submission deadline 25 Mar 2026 | 1 articles | Viewed by 630 | Submission Open
Keywords: translational immunology; autoimmune disease; autoinflammatory disease; immune-mediated diseases; oncology; preclinical models; immune efficacy and safety; mechanism of action; immunotoxicity assessment
(This special issue belongs to the Section Immunology & Rheumatology)
Diagnosis and Treatment of Sjogren’s Syndrome: 2nd Edition
edited by
submission deadline 15 Apr 2026 | 1 articles | Viewed by 3125 | Submission Open
Keywords: biological agents; JAK inhibitors; magnetic resonance imaging; noncoding RNA; Sjö gren's syndrome; ultrasound
(This special issue belongs to the Section Immunology & Rheumatology)
Pharmacotherapy and Patient Care in Rheumatoid Arthritis
edited by
submission deadline 15 Apr 2026 | Viewed by 54 | Submission Open
Keywords: rheumatoid arthritis; pharmacotherapy; patient care; biomarkers; treatment outcomes
(This special issue belongs to the Section Immunology & Rheumatology)
Cardiovascular Risks in Autoimmune and Inflammatory Diseases
edited by and
submission deadline 20 Apr 2026 | 5 articles | Viewed by 5756 | Submission Open
Keywords: autoimmune diseases; inflammation; cardiovascular risk; atherosclerosis; biological therapy; immunomodulatory therapy; lipid metabolism; cardiovascular risk factors; thrombosis; endothelial dysfunction
(This special issue belongs to the Section Immunology & Rheumatology)
News in the Pathogenesis, Diagnosis and Treatment of Systemic Sclerosis
edited by Mayka Freire and Bernardo Sopeña
submission deadline 20 Apr 2026 | 2 articles | Viewed by 2934 | Submission Open
Keywords: systemic sclerosis; scleroderma; capillaroscopy; autoantibodies; pathogenesis
(This special issue belongs to the Section Immunology & Rheumatology)
Innate Immunity in Overdrive: Novel Insights into Autoinflammatory Syndromes
edited by Alessandro Conforti
submission deadline 20 Apr 2026 | 1 articles | Viewed by 218 | Submission Open
Keywords: autoinflammatory diseases; innate immunity; inflammasome; cytokines; Interleukin-1; monogenic syndromes; polygenic autoinflammatory disorders; adult-onset Still’ s disease; Behç et’ s disease; targeted therapy; disease registries; real-world evidence; VEXAS syndrome; UBA1 mutations; precision medicine; biomarkers; outcome assessment
(This special issue belongs to the Section Immunology & Rheumatology)
Advances in Clinical Rheumatology—2nd Edition
edited by
submission deadline 20 May 2026 | 1 articles | Viewed by 464 | Submission Open
Keywords: rheumatoid arthritis; spondylarthritis; interventional; osteoporosis; complex regional pain syndrome
(This special issue belongs to the Section Immunology & Rheumatology)
Diagnosis and Treatment of Connective Tissue Diseases: A Clinician's Perspective: 2nd Edition
edited by , and Aleksandra Dańczak-Pazdrowska
submission deadline 20 May 2026 | Viewed by 70 | Submission Open
Keywords: connective tissue diseases; lupus erythematosus; scleroderma; dermatomyositis; MCTD; clinical picture; spectrum of clinical symptoms; treatment; complications; clinical follow-up
(This special issue belongs to the Section Immunology & Rheumatology)
Sjogren’s Syndrome: Clinical Advances and Insights
edited by David A. Isenberg
submission deadline 7 Jun 2026 | Viewed by 43 | Submission Open
Keywords: xerostomia; xerophthalmia; non-Hodgkins lymphoma; autoimmune rheumatic diseases; Sjogren’ s syndrome
(This special issue belongs to the Section Immunology & Rheumatology)
Hematoinflammatory Diseases: Bridging Autoimmunity and Autoinflammation
edited by Andrés González García and
submission deadline 20 Jun 2026 | Viewed by 37 | Submission Open
Keywords: hematoinflammatory diseases; clonal hematopoiesis; vexas syndrome; castleman disease; Igg4-related disease; cytokine storm; autoinflammatory syndromes; immunopathogenesis; targeted therapies; biomarkers
(This special issue belongs to the Section Immunology & Rheumatology)
Advances in Immunohematology: From Pathophysiology to Tailored Treatments submission deadline 25 Jun 2026 | Viewed by 31 | Submission Open
Keywords: autoimmune cytopenia; hemophagocytic lymphohistiocytosis; inborn errors of immunity; lymphoproliferative diseases; malignancy; monoclonal antibodies; secondary immunodeficiency; vaccination
(This special issue belongs to the Section Immunology & Rheumatology)
The Wide World of Antinuclear Antibodies (ANA)-Associated Disorders: Patterns, Clinical Phenotypes, Comorbidities, and Impact submission deadline 20 Jul 2026 | Viewed by 4 | Submission Open
Keywords: antinuclear antibodies (ANA); ANA-associated disorders; clinical phenotypes; ANA patterns; lupus; Sjö gren’ s disease; systemic sclerosis; idiopathic inflammatory myopathies; comorbidities; connective tissue diseases; overlap syndromes; undifferentiated connective tissue disease; risk stratification; patient-centered management
(This special issue belongs to the Section Immunology & Rheumatology)
Improving Outcomes in Systemic Lupus Erythematosus: Latest Advances and Prospects in Relation to Comorbidity, Damage, and Quality of Life
edited by and Shaye Kivity
submission deadline 30 Jul 2026 | Viewed by 58 | Submission Open
Keywords: systemic lupus erythematosus; comorbidities; outcome measures; damage accrual; quality of life; cognitive im-pairment; infections and vaccination; treat-to-target; digital biomarkers
(This special issue belongs to the Section Immunology & Rheumatology)
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