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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Updates on Rheumatoid Arthritis: From Diagnosis to Treatment

edited by

Carlos Alves

submission deadline 25 Aug 2025 | 1 articles | Viewed by 916 | Submission Open

Keywords: rheumatoid arthritis; pharmacological intervention; treatment; clinical development; effectiveness; safety; immune therapy; biological disease-modifying antirheumatic drugs (bDMARDs); synthetic disease-modifying antirheumatic drugs (sDMARDs)

(This special issue belongs to the Section Immunology)

Systemic Lupus Erythematosus: Current Trends and Therapeutic Innovations

edited by Giuseppe Barilaro

submission deadline 28 Aug 2025 | 3 articles | Viewed by 1941 | Submission Open

Keywords: systemic lupus erythematosus; autoantibodies; biomarkers; therapeutic drugs; lupus nephritis; quality of life; new treatment strategies

(This special issue belongs to the Section Immunology)

Targeted Treatment in Chronic Inflammatory Arthritis

edited by

Cinzia Rotondo

Simone Parisi

and Simone Perniola

submission deadline 30 Aug 2025 | 4 articles | Viewed by 4224 | Submission Open

Keywords: rheumatoid arthritis; psoriatic arthritis; ankylosing spondylitis; spondyloarthritis; disease-modifying antirheumatic drugs (DMARDs); personalized medicine; immunomodulatory therapies; patient outcomes; combination therapies

(This special issue belongs to the Section Immunology)

The Future of Inflammatory Biomarkers: Challenges and Clinical Integration

edited by

Sabina Galiniak

and

Marek Biesiadecki

submission deadline 31 Aug 2025 | 3 articles | Viewed by 5158 | Submission Open

Keywords: inflammatory marker; inflammation; biomarker; cancers; rheumatoid arthritis; inflammatory bowel disease; respiratory diseases

(This special issue belongs to the Section Immunology)

Antiphospholipid Syndrome: Clinical Advances in Diagnosis and Management

edited by Mattia Galli and

Alessandra Ida Celia

submission deadline 15 Sep 2025 | 4 articles | Viewed by 8687 | Submission Open

Keywords: antiphospholipid syndrome; antiphospholipid antibodies; systemic lupus erythematosus; immunosuppressive therapy; diagnosis; management

(This special issue belongs to the Section Immunology)

Advances in Clinical Rheumatology

edited by

Jacopo Ciaffi

submission deadline 20 Sep 2025 | 11 articles | Viewed by 19722 | Submission Open

Keywords: rheumatoid arthritis; spondyloarthritis; interventional; osteoporosis; complex regional pain syndrome

(This special issue belongs to the Section Immunology)

Inborn Errors of Immunity: Advances in Diagnosis and Treatment

edited by Jolanta Bernatoniene

submission deadline 25 Sep 2025 | 3 articles | Viewed by 9157 | Submission Open

Keywords: inborn errors of immunity (IEI); primary immunodeficiencies (PID); chronic granulomatous disease; PIK3CD mutations; immunology; autoimmunity

(This special issue belongs to the Section Immunology)

Diagnosis and Treatment of Sjogren’s Syndrome: 2nd Edition

edited by

Yoshiro Horai

submission deadline 15 Oct 2025 | 1 articles | Viewed by 673 | Submission Open

Keywords: biological agents; JAK inhibitors; magnetic resonance imaging; noncoding RNA; Sjö gren's syndrome; ultrasound

(This special issue belongs to the Section Immunology)

Advances in Allergic Diseases and Asthma: Clinical Insights and Emerging Therapies

edited by

Zenon Brzoza

submission deadline 20 Oct 2025 | 5 articles | Viewed by 10124 | Submission Open

Keywords: allergic diseases; asthma management; airway obstruction; allergy diagnosis; angioedema; urticaria

(This special issue belongs to the Section Immunology)

Cardiovascular Risks in Autoimmune and Inflammatory Diseases

edited by

Elena Rezus

and

Ciprian Rezus

submission deadline 20 Oct 2025 | 3 articles | Viewed by 2360 | Submission Open

Keywords: autoimmune diseases; inflammation; cardiovascular risk; atherosclerosis; biological therapy; immunomodulatory therapy; lipid metabolism; cardiovascular risk factors; thrombosis; endothelial dysfunction

(This special issue belongs to the Section Immunology)

News in the Pathogenesis, Diagnosis and Treatment of Systemic Sclerosis

edited by Mayka Freire and Bernardo Sopeña

submission deadline 24 Oct 2025 | 2 articles | Viewed by 2205 | Submission Open

Keywords: systemic sclerosis; scleroderma; capillaroscopy; autoantibodies; pathogenesis

(This special issue belongs to the Section Immunology)

Arthritis: From Diagnosis to Treatment

edited by Andrea Di Matteo and

Kulveer Mankia

submission deadline 20 Nov 2025 | 1 articles | Viewed by 874 | Submission Open

Keywords: rheumatoid arthritis; psoriatic arthritis; imaging; ultrasound; DMARDs; differential diagnosis; difficult to treat rheumatoid arthritis; prevention

(This special issue belongs to the Section Immunology)

Clinical Updates on Rheumatoid Arthritis: 2nd Edition

edited by Francesca Bandinelli

submission deadline 30 Nov 2025 | 1 articles | Viewed by 988 | Submission Open

Keywords: rheumatoid arthritis; rheumatology; treatment; diagnosis; biomarkers; rheumatic disease

(This special issue belongs to the Section Immunology)

Rheumatoid Arthritis: Challenges, Innovations and Outcomes

edited by

Marco Fornaro

submission deadline 15 Dec 2025 | 1 articles | Viewed by 843 | Submission Open

Keywords: rheumatoid arthritis; pathogenesis; treatments; outcomes; autoimmunity

(This special issue belongs to the Section Immunology)

Diagnosis and Treatment of Rheumatic Diseases

edited by Răzvan Gabriel Drăgoi and

Codrina Ancuta

submission deadline 20 Dec 2025 | 4 articles | Viewed by 5322 | Submission Open

Keywords: rheumatic diseases; patient-reported outcomes; assessment; arthritis; impairment; connective tissue diseases; biological and targeted synthetic therapies; impairment

(This special issue belongs to the Section Immunology)

Clinical Treatment and Management of Rheumatic Diseases, Autoinflammatory Diseases, and Autoimmune Disorders

edited by Merav Lidar and

Abdulla Watad

submission deadline 20 Dec 2025 | 3 articles | Viewed by 3716 | Submission Open

Keywords: rheumatic diseases; autoinflammatory diseases; autoimmune disorders; rheumatoid arthritis; diagnosis

(This special issue belongs to the Section Immunology)

Clinical Advances in Antiphospholipid Syndrome (APS)

edited by

Ariela Hoxha

submission deadline 30 Dec 2025 | Viewed by 91 | Submission Open

Keywords: thrombosis; pregnancy; antiphospholipid syndrome; lupus anticoagulant; antiphospholipid antibodies

(This special issue belongs to the Section Immunology)

Autoimmune Diseases and Multisystem Inflammation: Pathophysiology and Therapeutic Strategies

edited by

Tsuyoshi Shirai

submission deadline 30 Dec 2025 | Viewed by 87 | Submission Open

Keywords: autoimmune diseases; cardiovascular diseases; cutaneous diseases; gastrointestinal diseases; pulmonary diseases; renal diseases; systemic manifestation; rheumatoid arthritis; systemic lupus erythematosus; vasculitis

(This special issue belongs to the Section Immunology)

Rheumatoid Arthritis: Clinical Updates on Diagnosis and Treatment

edited by

Shunsuke Mori

submission deadline 20 Jan 2026 | 10 articles | Viewed by 22010 | Submission Open

Keywords: rheumatoid arthritis; disease-modifying antirheumatic drugs (DMARDs); biological therapies; Janus kinase inhibitors (JAK inhibitors); treatment strategies; joint destruction; comorbidity; drug safety

(This special issue belongs to the Section Immunology)

POTS, ME/CFS and Long COVID: Recent Advances and Future Direction

edited by Svetlana Blitshteyn

submission deadline 20 Jan 2026 | 1 articles | Viewed by 3555 | Submission Open

Keywords: POTS; ME/CFS; long COVID; dysautonomia; orthostatic intolerance; autoimmunity

(This special issue belongs to the Section Immunology)

Current and Emerging Therapies for Rheumatoid Arthritis

edited by

Yoshiro Horai

submission deadline 20 Jan 2026 | 1 articles | Viewed by 2347 | Submission Open

Keywords: DMARDs (disease-modifying anti-rheumatic drugs); boDMARDs (biological DMARDs); bsDMARDs (biosimilar DMARDs); csDMARDs (conventional synthetic DMARDs); rheumatoid arthritis; tsDMARDs (targeted synthetic DMARDs)

(This special issue belongs to the Section Immunology)

Clinical Advances in Autoimmune Disorders

edited by

Chiara Pellicano

and

Edoardo Rosato

submission deadline 20 Jan 2026 | 2 articles | Viewed by 1433 | Submission Open

Keywords: systemic sclerosis; Raynaud’ s phenomenon; digital ulcers; scleroderma renal crisis; pulmonary arterial hypertension; interstitial lung disease; fibrosis

(This special issue belongs to the Section Immunology)

Allergen-Specific Immunotherapy (AIT) for Allergic Diseases of the Respiratory Tract and Food Allergies

edited by

Ralph Mösges

submission deadline 20 Jan 2026 | 1 articles | Viewed by 1328 | Submission Open

Keywords: allergy; allergic rhinitis; allergic conjunctivitis; allergic asthma; food allergy; peptide immunotherapy; allergoids; SLIT; SCIT; OIT

(This special issue belongs to the Section Immunology)

Preventive Strategies and Novel Treatments for Rheumatoid Arthritis

edited by

Vincent Goeb

submission deadline 20 Jan 2026 | Viewed by 91 | Submission Open

Keywords: rheumatoid arthritis; antibodies; biologics; JAK; environment; susceptibility; therapeutic strategies

(This special issue belongs to the Section Immunology)

Rheumatoid Arthritis: Insights into Appropriate Diagnosis, Treatment and Management

edited by

Satoshi Takanashi

submission deadline 20 Feb 2026 | Viewed by 61 | Submission Open

Keywords: rheumatoid arthritis; precision medicine; difficult-to-treat rheumatoid arthritis; late-onset rheumatoid arthritis; ageing society; comorbidities

(This special issue belongs to the Section Immunology)

Allergic and Eosinophilic Diseases: Diagnosis, Treatment and Management (Second Edition)

edited by Aikaterini Detoraki

submission deadline 25 Feb 2026 | Viewed by 36 | Submission Open

Keywords: allergy; eosinophilic diseases; immunology; clinical immunology; asthma; diagnosis; treatment; management

(This special issue belongs to the Section Immunology)

Translational Immunology in Clinical Medicine: From Preclinical Insights to Therapeutic Impact

edited by

Soheil Tavakolpour

submission deadline 25 Mar 2026 | Viewed by 57 | Submission Open

Keywords: translational immunology; autoimmune disease; autoinflammatory disease; immune-mediated diseases; oncology; preclinical models; immune efficacy and safety; mechanism of action; immunotoxicity assessment

(This special issue belongs to the Section Immunology)

Pharmacotherapy and Patient Care in Rheumatoid Arthritis

edited by

Ryu Watanabe

submission deadline 15 Apr 2026 | Submission Open

Keywords: rheumatoid arthritis; pharmacotherapy; patient care; biomarkers; treatment outcomes

(This special issue belongs to the Section Immunology)

Innate Immunity in Overdrive: Novel Insights into Autoinflammatory Syndromes

edited by Alessandro Conforti

submission deadline 20 Apr 2026 | Viewed by 27 | Submission Open

Keywords: autoinflammatory diseases; innate immunity; inflammasome; cytokines; Interleukin-1; monogenic syndromes; polygenic autoinflammatory disorders; adult-onset Still’ s disease; Behç et’ s disease; targeted therapy; disease registries; real-world evidence; VEXAS syndrome; UBA1 mutations; precision medicine; biomarkers; outcome assessment

(This special issue belongs to the Section Immunology)

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