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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Psoriatic Arthritis—New Insights, Challenges, Unmet Needs and Controversies submission deadline 20 May 2025 | 2 articles | Viewed by 2288 | Submission Open
Keywords: psoriatic arthritis; psoriasis; enthesitis; dactylitis; spondyloarthritis; radiological progression; biologics; JAK-inhibitors; immune-mediated inflammatory diseases; comorbidities
(This special issue belongs to the Section Immunology)
Arthritis: From Diagnosis to Treatment
edited by Andrea Di Matteo and
submission deadline 25 May 2025 | Viewed by 287 | Submission Open
Keywords: rheumatoid arthritis; psoriatic arthritis; imaging; ultrasound; DMARDs; differential diagnosis; difficult to treat rheumatoid arthritis; prevention
(This special issue belongs to the Section Immunology)
Rheumatoid Arthritis: Challenges, Innovations and Outcomes
edited by
submission deadline 30 May 2025 | Viewed by 329 | Submission Open
Keywords: rheumatoid arthritis; pathogenesis; treatments; outcomes; autoimmunity
(This special issue belongs to the Section Immunology)
Progress in Diagnosis and Treatment of Primary Immunodeficiencies submission deadline 31 May 2025 | 4 articles | Viewed by 9408 | Submission Open
Keywords: primary immunodeficiencies; autoimmune manifestations; PIDs
(This special issue belongs to the Section Immunology)
Systemic Autoinflammatory Diseases—Clinical Rheumatic Challenges: 3rd Edition
edited by
submission deadline 31 May 2025 | 3 articles | Viewed by 5993 | Submission Open
Keywords: autoinflammation; inflammasome; inflammasomopathies; interferonopathies; relopathies; proteasome-associated syndromes; syndrome of undifferentiated recurrent fever; pro-inflammatory cytokines; biomarkers.
(This special issue belongs to the Section Immunology)
Clinical Updates on Rheumatoid Arthritis: 2nd Edition
edited by Francesca Bandinelli
submission deadline 31 May 2025 | 1 articles | Viewed by 239 | Submission Open
Keywords: rheumatoid arthritis; rheumatology; treatment; diagnosis; biomarkers; rheumatic disease
(This special issue belongs to the Section Immunology)
Clinical Treatment and Management of Rheumatic Diseases, Autoinflammatory Diseases, and Autoimmune Disorders
edited by Merav Lidar and
submission deadline 24 Jun 2025 | 2 articles | Viewed by 2267 | Submission Open
Keywords: rheumatic diseases; autoinflammatory diseases; autoimmune disorders; rheumatoid arthritis; diagnosis
(This special issue belongs to the Section Immunology)
Diagnosis and Treatment of Rheumatic Diseases
edited by Răzvan Gabriel Drăgoi and
submission deadline 30 Jun 2025 | 3 articles | Viewed by 2659 | Submission Open
Keywords: rheumatic diseases; patient-reported outcomes; assessment; arthritis; impairment; connective tissue diseases; biological and targeted synthetic therapies; impairment
(This special issue belongs to the Section Immunology)
Allergen-Specific Immunotherapy (AIT) for Allergic Diseases of the Respiratory Tract and Food Allergies
edited by
submission deadline 30 Jun 2025 | 1 articles | Viewed by 636 | Submission Open
Keywords: allergy; allergic rhinitis; allergic conjunctivitis; allergic asthma; food allergy; peptide immunotherapy; allergoids; SLIT; SCIT; OIT
(This special issue belongs to the Section Immunology)
Current and Emerging Therapies for Rheumatoid Arthritis
edited by
submission deadline 10 Jul 2025 | 1 articles | Viewed by 1502 | Submission Open
Keywords: DMARDs (disease-modifying anti-rheumatic drugs); boDMARDs (biological DMARDs); bsDMARDs (biosimilar DMARDs); csDMARDs (conventional synthetic DMARDs); rheumatoid arthritis; tsDMARDs (targeted synthetic DMARDs)
(This special issue belongs to the Section Immunology)
Advances in Rheumatology: From Bench to Bedside
edited by
submission deadline 15 Jul 2025 | 2 articles | Viewed by 2046 | Submission Open
Keywords: autoimmune disease; inflammation pathophysiology; novel therapeutic strategies; translational medicine; bench to bedside (B2B); disease biomarkers
(This special issue belongs to the Section Immunology)
Rheumatoid Arthritis: Clinical Updates on Diagnosis and Treatment
edited by
submission deadline 31 Jul 2025 | 9 articles | Viewed by 12643 | Submission Open
Keywords: rheumatoid arthritis; disease-modifying antirheumatic drugs (DMARDs); biological therapies; Janus kinase inhibitors (JAK inhibitors); treatment strategies; joint destruction; comorbidity; drug safety
(This special issue belongs to the Section Immunology)
Clinical Advances in Systemic Sclerosis submission deadline 31 Jul 2025 | 1 articles | Viewed by 577 | Submission Open
Keywords: systemic sclerosis; Raynaud’ s phenomenon; digital ulcers; scleroderma renal crisis; pulmonary arterial hypertension; interstitial lung disease; fibrosis
(This special issue belongs to the Section Immunology)
Immune Dysregulation in Inborn Errors of Immunity: From Allergy to Autoimmunity and Lymphoproliferation submission deadline 10 Aug 2025 | 2 articles | Viewed by 2779 | Submission Open
Keywords: immune dysregulation; immunodeficiency; autoimmunity; allergy; lymphoproliferation; inborn errors of immunity
(This special issue belongs to the Section Immunology)
Updates on Rheumatoid Arthritis: From Diagnosis to Treatment
edited by
submission deadline 25 Aug 2025 | Viewed by 301 | Submission Open
Keywords: rheumatoid arthritis; pharmacological intervention; treatment; clinical development; effectiveness; safety; immune therapy; biological disease-modifying antirheumatic drugs (bDMARDs); synthetic disease-modifying antirheumatic drugs (sDMARDs)
(This special issue belongs to the Section Immunology)
Systemic Lupus Erythematosus: Current Trends and Therapeutic Innovations
edited by Giuseppe Barilaro
submission deadline 28 Aug 2025 | Viewed by 127 | Submission Open
Keywords: systemic lupus erythematosus; autoantibodies; biomarkers; therapeutic drugs; lupus nephritis; quality of life; new treatment strategies
(This special issue belongs to the Section Immunology)
Targeted Treatment in Chronic Inflammatory Arthritis
edited by , and Simone Perniola
submission deadline 30 Aug 2025 | 2 articles | Viewed by 1327 | Submission Open
Keywords: rheumatoid arthritis; psoriatic arthritis; ankylosing spondylitis; spondyloarthritis; disease-modifying antirheumatic drugs (DMARDs); personalized medicine; immunomodulatory therapies; patient outcomes; combination therapies
(This special issue belongs to the Section Immunology)
The Future of Inflammatory Biomarkers: Challenges and Clinical Integration submission deadline 31 Aug 2025 | 3 articles | Viewed by 4122 | Submission Open
Keywords: inflammatory marker; inflammation; biomarker; cancers; rheumatoid arthritis; inflammatory bowel disease; respiratory diseases
(This special issue belongs to the Section Immunology)
Antiphospholipid Syndrome: Clinical Advances in Diagnosis and Management
edited by Mattia Galli and
submission deadline 15 Sep 2025 | 4 articles | Viewed by 2827 | Submission Open
Keywords: antiphospholipid syndrome; antiphospholipid antibodies; systemic lupus erythematosus; immunosuppressive therapy; diagnosis; management
(This special issue belongs to the Section Immunology)
Advances in Clinical Rheumatology
edited by
submission deadline 20 Sep 2025 | 11 articles | Viewed by 13857 | Submission Open
Keywords: rheumatoid arthritis; spondyloarthritis; interventional; osteoporosis; complex regional pain syndrome
(This special issue belongs to the Section Immunology)
Inborn Errors of Immunity: Advances in Diagnosis and Treatment
edited by Jolanta Bernatoniene
submission deadline 25 Sep 2025 | 2 articles | Viewed by 6629 | Submission Open
Keywords: inborn errors of immunity (IEI); primary immunodeficiencies (PID); chronic granulomatous disease; PIK3CD mutations; immunology; autoimmunity
(This special issue belongs to the Section Immunology)
Diagnosis and Treatment of Sjogren’s Syndrome: 2nd Edition
edited by
submission deadline 15 Oct 2025 | Viewed by 72 | Submission Open
Keywords: biological agents; JAK inhibitors; magnetic resonance imaging; noncoding RNA; Sjö gren's syndrome; ultrasound
(This special issue belongs to the Section Immunology)
Advances in Allergic Diseases and Asthma: Clinical Insights and Emerging Therapies
edited by
submission deadline 20 Oct 2025 | 3 articles | Viewed by 6217 | Submission Open
Keywords: allergic diseases; asthma management; airway obstruction; allergy diagnosis; angioedema; urticaria
(This special issue belongs to the Section Immunology)
Cardiovascular Risks in Autoimmune and Inflammatory Diseases
edited by and
submission deadline 20 Oct 2025 | Viewed by 60 | Submission Open
Keywords: autoimmune diseases; inflammation; cardiovascular risk; atherosclerosis; biological therapy; immunomodulatory therapy; lipid metabolism; cardiovascular risk factors; thrombosis; endothelial dysfunction
(This special issue belongs to the Section Immunology)
News in the Pathogenesis, Diagnosis and Treatment of Systemic Sclerosis
edited by Mayka Freire and Bernardo Sopeña
submission deadline 24 Oct 2025 | 2 articles | Viewed by 1588 | Submission Open
Keywords: systemic sclerosis; scleroderma; capillaroscopy; autoantibodies; pathogenesis
(This special issue belongs to the Section Immunology)
Clinical Advances in Antiphospholipid Syndrome (APS)
edited by
submission deadline 30 Dec 2025 | Viewed by 28 | Submission Open
Keywords: thrombosis; pregnancy; antiphospholipid syndrome; lupus anticoagulant; antiphospholipid antibodies
(This special issue belongs to the Section Immunology)
Autoimmune Diseases and Multisystem Inflammation: Pathophysiology and Therapeutic Strategies
edited by
submission deadline 30 Dec 2025 | Viewed by 22 | Submission Open
Keywords: autoimmune diseases; cardiovascular diseases; cutaneous diseases; gastrointestinal diseases; pulmonary diseases; renal diseases; systemic manifestation; rheumatoid arthritis; systemic lupus erythematosus; vasculitis
(This special issue belongs to the Section Immunology)
POTS, ME/CFS and Long COVID: Recent Advances and Future Direction
edited by Svetlana Blitshteyn
submission deadline 20 Jan 2026 | Viewed by 226 | Submission Open
Keywords: POTS; ME/CFS; long COVID; dysautonomia; orthostatic intolerance; autoimmunity
(This special issue belongs to the Section Immunology)
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