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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Clinical Updates on Dyslipidemia
edited by
submission deadline 31 Jan 2026 | Viewed by 48 | Submission Open
Keywords: dyslipidemia; cardiovascular disease; prevention; treatment; risk factors
(This special issue belongs to the Section Cardiovascular Medicine)
Trauma Surgery: Strategies, Challenges and Vision of the Future
edited by Shai Factor and Yaniv S. Warschawski
submission deadline 31 Jan 2026 | Viewed by 35 | Submission Open
Keywords: orthopaedic surgery; fractures; injuries; upper limb; trauma
(This special issue belongs to the Section Clinical Research Methods)
Exercise, Injury and Rehabilitation: Integrated Perspectives in Sports Medicine submission deadline 3 Feb 2026 | Viewed by 150 | Submission Open
Keywords: sports medicine; biomechanics; injury prevention; exercise physiology; sports performance; load management; exercise prescription; return to play; recovery
(This special issue belongs to the Section Sports Medicine)
Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) as a Global but Not Liver-Limited Health Challenge—from Disease Pathogenesis to Therapeutic Targets
edited by Beata Kasztelan-Szczerbinska and Halina Cichoż-Lach
submission deadline 5 Feb 2026 | 3 articles | Viewed by 4536 | Submission Open
Keywords: metabolic dysfunction-associated steatotic liver disease (MASLD); non-alcoholic fatty liver disease (NAFLD); hepatic steatosis; multiorgan metabolic interactions; liver-related morbidity; liver-related mortality; lipid metabolism; cardiovascular metabolic complications; metabolic dysfunction-related cancer
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
New Advances and Clinical Outcomes of Cardiothoracic Surgery
edited by Hee-Jung Kim and
submission deadline 5 Feb 2026 | Viewed by 61 | Submission Open
Keywords: cardiac surgery; coronary artery bypass grafting; heart valve surgery; aortic intervention; materials; precision medicine; artificial intelligence
(This special issue belongs to the Section General Surgery)
Physical Therapy in Neurorehabilitation: Innovations, Challenges and Opportunities submission deadline 6 Feb 2026 | Viewed by 43 | Submission Open
Keywords: neurorehabilitation; physical activity; neurocognitive rehabilitation; neurogenic bladder; fatigue; sexual dysfunction; accessibility
(This special issue belongs to the Section Clinical Neurology)
Clinical Updates and Perspectives of Implant Dentistry submission deadline 10 Feb 2026 | 1 articles | Viewed by 5643 | Submission Open
Keywords: osseointegration; soft tissue integration; peri-implant diseases
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Current Challenges and Advancements in Lateral Skull Base Surgery
edited by Alessia Rubini
submission deadline 10 Feb 2026 | 1 articles | Viewed by 1090 | Submission Open
Keywords: lateral skull base; neurotology; jugular foramen; cerebellopontine angle; petrous apex; inner ear; acoustic neuroma; jugular paraganglioma; transtemporal approaches; infratemporal approaches
(This special issue belongs to the Section Otolaryngology)
Plastic and Reconstructive Surgery: Cutting-Edge Expert Perspective
edited by and
submission deadline 10 Feb 2026 | 1 articles | Viewed by 602 | Submission Open
Keywords: plastic and reconstructive surgery; new perspectives; regeneration; microsurgery; oncoplastic; post bariatric; breast implant
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Application of Anticoagulation and Antiplatelet Therapy submission deadline 10 Feb 2026 | 1 articles | Viewed by 505 | Submission Open
Keywords: antiplatelets; anticoagulants; atherothrombosis; coronary artery disease; peripheral artery disease; cerebral artery disease; vitamin K antagonists; direct oral anticoagulants; clopidogrel; aspirin; ticagrelor; prasugrel
(This special issue belongs to the Section Cardiovascular Medicine)
The Journey of Hearing and Hearing-Related Disorders over Time—2nd Edition submission deadline 10 Feb 2026 | Viewed by 216 | Submission Open
Keywords: hearing; hearing journey; hearing-related disorders; tinnitus; hyperacusis; digital phenotyping; big data
(This special issue belongs to the Section Otolaryngology)
Minimally Invasive Approaches to Urolithiasis and Upper Urinary Tract Transitional Cell Carcinoma: Current Evidence
edited by
submission deadline 10 Feb 2026 | Viewed by 141 | Submission Open
Keywords: extracorporeal shock wave lithotripsy; lasers; percutaneous lithotripsy; robotic surgery; ureteroscopy; urolithiasis
(This special issue belongs to the Section Nephrology & Urology)
Hearing Disorders: Diagnosis, Management, and Future Opportunities: 4th Edition
edited by
submission deadline 10 Feb 2026 | Viewed by 78 | Submission Open
Keywords: middle ear surgery; otosclerosis; sensorineural hearing loss; sudden hearing; cochlear implant
(This special issue belongs to the Section Otolaryngology)
Clinical Advances in Pediatric Critical Care Medicine
edited by
submission deadline 10 Feb 2026 | Viewed by 75 | Submission Open
Keywords: acute renal failure; acute respiratory failure; pediatric oncology; pediatric ICU; pediatric critical care medicine; multi-organ dysfunction
(This special issue belongs to the Section Clinical Pediatrics)
Infectious Disease Epidemiology: Current Updates and Perspectives submission deadline 10 Feb 2026 | Viewed by 72 | Submission Open
Keywords: infection prevention and control; infectious diseases epidemiology; public health; novel treatments
(This special issue belongs to the Section Infectious Diseases)
Advancements and Future Directions in Clinical Psychosis submission deadline 10 Feb 2026 | Viewed by 71 | Submission Open
Keywords: clinical psychosis; schizophrenia spectrum disorders; early detection of psychosis; treatment-resistant psychosis; long-term outcomes; personalized psychiatry; digital mental health; AI in psychiatry; neurocognitive interventions; psychosocial therapies; translational psychiatry; interdisciplinary mental health; psychosis clinical trials; innova-tive diagnostic tools
(This special issue belongs to the Section Mental Health)
Management of Congenital Heart Disease (CHD)
edited by Sarah Nordmeyer and Marie Schafstedde
submission deadline 10 Feb 2026 | Viewed by 66 | Submission Open
Keywords: congenital heart disease; imaging; diagnostics; surgical innovations; minimally invasive interventions
(This special issue belongs to the Section Cardiovascular Medicine)
Recent Concepts in Ovarian Cancer: Epidemiology, Diagnosis, Treatment and Quality of Life
edited by Giulia Scotto and
submission deadline 10 Feb 2026 | Viewed by 65 | Submission Open
Keywords: ovarian cancer; quality of life; multidisciplinary care; personalized medicine; PARP inhibitors
(This special issue belongs to the Section Oncology)
Clinical Advances in Spine Disorders—2nd Edition submission deadline 10 Feb 2026 | Viewed by 65 | Submission Open
Keywords: spine disorders; lumbar spine surgery; minimally invasive surgery; spine surgery; microneurosurgery
(This special issue belongs to the Section Clinical Neurology)
Clinical Advances in Pain Management
edited by Jamal Hasoon and Omar Viswanath
submission deadline 13 Feb 2026 | 5 articles | Viewed by 6517 | Submission Open
Keywords: postoperative pain; acute pain; chronic pain; nociceptive; analgesia; analgesics; interventional pain procedures
(This special issue belongs to the Section Anesthesiology)
Systemic Lupus Erythematosus: Current Trends and Therapeutic Innovations
edited by Giuseppe Barilaro
submission deadline 15 Feb 2026 | 4 articles | Viewed by 2396 | Submission Open
Keywords: systemic lupus erythematosus; autoantibodies; biomarkers; therapeutic drugs; lupus nephritis; quality of life; new treatment strategies
(This special issue belongs to the Section Immunology & Rheumatology)
Pancreatic Disorder, Pancreatitis, and Pancreatic Cancer: Interconnections, Clinical Challenges, and Therapeutic Advances
edited by Cristian George Ţieranu and
submission deadline 15 Feb 2026 | Viewed by 2065 | Submission Open
Keywords: pancreatic disorder; pancreatitis; pancreatic cancer; translational research; diagnosis; treatment
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Cardiac Electrophysiology: Focus on Clinical Practice submission deadline 15 Feb 2026 | 2 articles | Viewed by 1405 | Submission Open
Keywords: cardiomyopathy; arrhythmia; heart rhythm; atrial fibrillation; ventricular tachycardia; sudden cardiac death; mapping; ablation; pulsed field ablation (PFA); device; pacemaker; left bundle branch area pacing (LBBAP); conduction system pacing (CSP); implantable cardioverter-defibrillator (ICD); leadless pacing; extraction
(This special issue belongs to the Section Cardiology)
Periodontal Diseases and Systemic Health: Pathogenesis, Prevention and Management
edited by Saverio Cosola
submission deadline 15 Feb 2026 | 2 articles | Viewed by 1030 | Submission Open
Keywords: periodontitis; dental implants; systemic inflammation; diabetes and periodontal disease; cardiovascular implications; pregnancy and oral health; host immune responses; preventive dentistry; implant-prosthetic rehabilitation
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Current Concepts and Updates in Eye Diseases
edited by Wiktor Stopyra, and Anna Machalinski
submission deadline 15 Feb 2026 | 2 articles | Viewed by 964 | Submission Open
Keywords: corneal disease; glaucoma; cataract; uveitis; ocular oncology; retinal disorder; ocular treatment; eye surgery; ocular diagnostics
(This special issue belongs to the Section Ophthalmology)
Catheter Ablation of Cardiac Arrhythmias: Current Updates and Perspectives: 2nd Edition
edited by
submission deadline 15 Feb 2026 | 1 articles | Viewed by 759 | Submission Open
Keywords: ablation; arrhythmia; electrophysiology; atrial fibrillation; atrial flutter; atrial tachycardia; mapping; supraventricular tachycardia; ventricular arrhythmia
(This special issue belongs to the Section Cardiology)
Advances in Traumatic Brain Injury: Causes and Recovery
edited by Antonio Bonora
submission deadline 15 Feb 2026 | Viewed by 198 | Submission Open
Keywords: mild traumatic brain injury; TBI; brain injuries; neuroimaging; rehabilitation
(This special issue belongs to the Section Brain Injury)
Bariatric Surgery: Challenges and Future Trends
edited by Hugo Santos-Sousa
submission deadline 15 Feb 2026 | Viewed by 94 | Submission Open
Keywords: obesity; metabolic and bariatric surgery; sleeve gastrectomy; metabolic syndrome; novel surgical procedures; Nissen-sleeve fundoplication; Roux-en-Y gastric bypass distalization; single-anastomosis procedures
(This special issue belongs to the Section General Surgery)
Recent Advances in Refractive Surgery and Intraocular Lens Implantation
edited by Antonio Leccisotti
submission deadline 15 Feb 2026 | Viewed by 91 | Submission Open
Keywords: refractive surgery; intraocular lens implantation; keratectomy; cornea; ocular surgery; optical coherence tomography; laser surgery; KLEx (keratorefractive lenticule extraction); femtolasik
(This special issue belongs to the Section Ophthalmology)
Drug-Related Problems: Clinical Pharmacy and Safety of Pharmacotherapy submission deadline 15 Feb 2026 | Viewed by 89 | Submission Open
Keywords: adverse drug reaction; drug-related problems; drug formulation technology; safety of pharmacotherapy; clinical pharmacy; pharmaceutical care; pharmacology
(This special issue belongs to the Section Pharmacology)
Clinical Diagnosis and Surgical Strategies Update on Ear Disorders: 2nd Edition submission deadline 15 Feb 2026 | Viewed by 57 | Submission Open
Keywords: middle ear; inner ear; endoscopic ear surgery; cholesteatoma; Meniè re’ s disease; hearing loss; robotic surgery; oto-sclerosis
(This special issue belongs to the Section Otolaryngology)
State of the Art in Bladder Cancer: Diagnostics and Treatment Strategies
edited by
submission deadline 15 Feb 2026 | Viewed by 56 | Submission Open
Keywords: bladder cancer; photodynamic diagnosis (PDD); bladder-sparing strategies; robotic-assisted surgery; single-port robotic cystectomy; older patients; immunotherapy; intravesical therapy; bladder preservation; minimally invasive urology; advanced bladder cancer; diagnostic innovation
(This special issue belongs to the Section Nephrology & Urology)
Kidney Transplantation: Current Challenges and Future Perspectives: 2nd Edition
edited by Alberto Piana and Angelo Territo
submission deadline 15 Feb 2026 | Viewed by 52 | Submission Open
Keywords: kidney transplantation; urologic cancers; organ preservation; surgical challenges; donor selection; long-term outcomes; complications; post-transplant care; technology
(This special issue belongs to the Section Nephrology & Urology)
Clinical Perspectives in Amyotrophic Lateral Sclerosis: Diagnosis, Management and Future Opportunities
edited by
submission deadline 15 Feb 2026 | Viewed by 40 | Submission Open
Keywords: amyotrophic lateral sclerosis; early diagnosis; neuroimaging; biomarkers; treatment
(This special issue belongs to the Section Clinical Neurology)
New Insight into Pain and Chronic Pain Management
edited by
submission deadline 15 Feb 2026 | Viewed by 30 | Submission Open
Keywords: chronic pain; pain management; pharmacological treatment; non-pharmacological interventions; neuromodula-tion; multidisciplinary approaches; personalized medicine; quality of life
(This special issue belongs to the Section Clinical Rehabilitation)
Endocrine Malignancies: Current Surgical Therapeutic Approaches: 2nd Edition
edited by , and Marco Bononi
submission deadline 18 Feb 2026 | 4 articles | Viewed by 2181 | Submission Open
Keywords: endocrine malignancies; thyroid cancer; adrenocortical cancer; parathyroid; men
(This special issue belongs to the Section Endocrinology & Metabolism)
Eosinophilic Esophagitis: Clinical Advances in Diagnosis, Treatment, and Monitoring
edited by Pierfrancesco Visaggi, Edoardo Vincenzo Savarino and
submission deadline 18 Feb 2026 | 1 articles | Viewed by 2138 | Submission Open
Keywords: eosinophilic esophagitis (EoE); diagnosis  ; treatment  ; monitoring; disease assessment; precision medicine
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Sexually Transmitted Infections as a Challenge of Modern Society: Old Problems and Modern Solutions
edited by Mauro Zaccarelli and
submission deadline 20 Feb 2026 | 4 articles | Viewed by 8815 | Submission Open
Keywords: sexually transmitted infections (STIs); human papilloma virus (HPV); syphilis; gonorrhea; chlamydia trachomatis; HIV infection; PrEP; chemsex
(This special issue belongs to the Section Infectious Diseases)
Recent Developments in Gynecological Endocrinology submission deadline 20 Feb 2026 | 5 articles | Viewed by 8514 | Submission Open
Keywords: amenorrhea; puberty; PCOS; premature ovarian insufficiency; endometriosis; infertility; pregnancy; hormones; menopause
(This special issue belongs to the Section Obstetrics & Gynecology)
Sepsis: Current Updates and Perspectives submission deadline 20 Feb 2026 | 6 articles | Viewed by 7714 | Submission Open
Keywords: sepsis biomarkers; diagnostic tools; cytokines; inflammation; infection; antibiotherapy; blood purification; novel therapies
(This special issue belongs to the Section Intensive Care)
Cystic Fibrosis: Diagnosis and Treatment
edited by Corrado Tagliati and Gian Marco Giuseppetti
submission deadline 20 Feb 2026 | 5 articles | Viewed by 7492 | Submission Open
Keywords: cystic fibrosis; diagnosis; treatment; management
(This special issue belongs to the Section Respiratory Medicine)
Endodontic and Periodontal Medicine: Systemic Implications of Oral Infections submission deadline 20 Feb 2026 | 6 articles | Viewed by 5723 | Submission Open
Keywords: dentistry; endodontics; apical periodontitis; endodontic medicine; periodontal disease; periodontal medicine; pulpitis; systemic diseases; root canal treatment
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Orthopedic Surgery: Recent Advances and Prospects
edited by Mitchell K. Ng
submission deadline 20 Feb 2026 | 3 articles | Viewed by 4723 | Submission Open
Keywords: orthopedic surgery; clinical updates; joint reconstruction; spine surgery; trauma; elective surgery; peri-operative management
(This special issue belongs to the Section Orthopedics)
Preeclampsia and Other Pregnancy Complications: Early Intervention, Diagnosis and Management
edited by , and Mohamed Ahmed Mostafa Aboellail
submission deadline 20 Feb 2026 | 4 articles | Viewed by 4688 | Submission Open
Keywords: preeclampsia; pregnancy complications; early intervention; diagnosis of pregnancy complications; management of pregnancy complications; sexual dysfunctions in pregnancy
(This special issue belongs to the Section Obstetrics & Gynecology)
Clinical Updates on Hereditary Hemorrhagic Telangiectasia (HHT) and Other Vascular Diseases
edited by Tamás Major
submission deadline 20 Feb 2026 | 4 articles | Viewed by 4058 | Submission Open
Keywords: hereditary hemorrhagic telangiectasia (HHT); arteriovenous malformations; embolization; VEGF; capillary malformation-arteriovenous malformation
(This special issue belongs to the Section Vascular Medicine)
Interstitial Lung Disease: From Diagnosis to Treatment
edited by and Tomohisa Baba
submission deadline 20 Feb 2026 | 2 articles | Viewed by 4022 | Submission Open
Keywords: interstitial pneumonia; diagnosis; virus infection; collagen vascular disease-related interstitial pneumonia; differen-tial diagnosis; lung sounds
(This special issue belongs to the Section Respiratory Medicine)
Gastrointestinal Diseases: Clinical Challenges and Management
edited by Anusha Shirwaikar Thomas and
submission deadline 20 Feb 2026 | 2 articles | Viewed by 3105 | Submission Open
Keywords: GI bleed; nutrition; obstructive jaundice; drug-induced live injury; GI motility; clostridium difficile infection; large bowel obstruction; colon cancer prevention and surveillance
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Recent Advances in Immunotherapy of Cancer submission deadline 20 Feb 2026 | 2 articles | Viewed by 2909 | Submission Open
Keywords: immunotherapy; immunology; cancer; oncology; tumor immune microenvironment; artificial intelligence; immune-related adverse events
(This special issue belongs to the Section Oncology)
Updates on Lumbar Spine Surgery for Degenerative Diseases
edited by
submission deadline 20 Feb 2026 | 3 articles | Viewed by 2825 | Submission Open
Keywords: degenerative disease; lumbar spine surgery; fusion; decompressive surgery; sagittal alignment; complications; outcomes
(This special issue belongs to the Section Orthopedics)
The Complex Interplay Between Physical Activity, Sleep, Diet, and Obesity: Clinical Insights for Treatment and Prevention submission deadline 20 Feb 2026 | 4 articles | Viewed by 2484 | Submission Open
Keywords: body mass; body composition; nutrition; sleep patterns; weight management; lifestyle interventions; sedentary behavior; adiposity; obesity prevention; dietary habits
(This special issue belongs to the Section Clinical Rehabilitation)
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