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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Trends in Minimally Invasive Urological Surgery: Robot and Beyond
edited by Riccardo Giuseppe Bertolo and Alessandro Antonelli
submission deadline 25 May 2025 | 1 articles | Viewed by 918 | Submission Open
Keywords: minimally invasive surgery; robotic surgery; urology; innovation; surgical technology; patient outcomes; surgical robotics; laparoscopic surgery; artificial intelligence; augmented reality
(This special issue belongs to the Section Nephrology & Urology)
Arthritis: From Diagnosis to Treatment
edited by Andrea Di Matteo and
submission deadline 25 May 2025 | Viewed by 288 | Submission Open
Keywords: rheumatoid arthritis; psoriatic arthritis; imaging; ultrasound; DMARDs; differential diagnosis; difficult to treat rheumatoid arthritis; prevention
(This special issue belongs to the Section Immunology)
Challenges and Future Trends in Bariatric Surgery
edited by Maurizio L. de Luca and Amanda Belluzzi
submission deadline 25 May 2025 | Viewed by 280 | Submission Open
Keywords: metabolic and bariatric surgery; SADI-S; LSG; RYGB; SASI; OAGB; complications after MBS; long-term outcomes; malnutrition
(This special issue belongs to the Section General Surgery)
Innovations in Clinical Artificial Intelligence: Image Analysis, Prediction, and Treatment Optimization
edited by Shahriar Faghani
submission deadline 25 May 2025 | Viewed by 239 | Submission Open
Keywords: artificial intelligence; clinical practice; prediction; diagnosis; treatment
Clinical Updates on Prosthodontics
edited by and Carla Fons-Badal
submission deadline 25 May 2025 | Viewed by 233 | Submission Open
Keywords: dental prosthesis; dental implants; gingival treatment; gingival aesthetics; gingival treatment; dental aesthetics; dental ceramics; BOPT; surgical periodontal treatment
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Modern Blood Banking and Transfusion in Clinical Practice: Second Edition
edited by
submission deadline 25 May 2025 | Viewed by 232 | Submission Open
Keywords: blood transfusion therapy; patient blood management; restrictive transfusion; cell therapy; platelet transfusion
(This special issue belongs to the Section Hematology)
Clinical Application of Left Ventricular Assist Devices
edited by Themistokles Chamogeorgakis
submission deadline 25 May 2025 | Viewed by 201 | Submission Open
Keywords: ventricular assist device; LVAD; RVAD; heart failure; right ventricular failure; continuous flow pump; volume displacement pump; centrifugal pump; magnetically levitated pump; survival
(This special issue belongs to the Section Cardiology)
Clinical Advances in Obesity and Bariatric Surgery
edited by Valentin Mocanu and Jerry Dang
submission deadline 27 May 2025 | 9 articles | Viewed by 15374 | Submission Open
Keywords: obesity; bariatric surgery; metabolic surgery; anti-obesity medications; obesity treatment
(This special issue belongs to the Section Endocrinology & Metabolism)
Oral Hygiene: Updates and Clinical Progress
edited by
submission deadline 28 May 2025 | 6 articles | Viewed by 4865 | Submission Open
Keywords: periodontal disease; dental caries; plaque control; oral hygiene practices; gingivitis; dental prophylaxis; oral health education
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
New Trends in Mechanical Ventilation
edited by
submission deadline 28 May 2025 | 1 articles | Viewed by 3209 | Submission Open
Keywords: positive pressure ventilation; negative pressure ventilation; constant flow ventilation; PEEP; lung recruitment; obesity; laparoscopy; ARDS; atelectasis; total lung compliance
(This special issue belongs to the Section Anesthesiology)
Neuro-Oncology: Diagnosis and Treatment
edited by Shunsuke Shibao
submission deadline 28 May 2025 | 2 articles | Viewed by 2117 | Submission Open
Keywords: neuro-oncology; genetic diagnostics; biomarker-based diagnostics; AI-based image diagnosis; preoperative simulation; augmented reality (AR); virtual reality (VR); endoscopic surgery; minimally invasive surgery; skull base surgery
(This special issue belongs to the Section Clinical Neurology)
Advances in the Diagnosis and Management of Age-Related Macular Degeneration: 2nd Edition
edited by Tsutomu Yasukawa
submission deadline 28 May 2025 | 4 articles | Viewed by 2070 | Submission Open
Keywords: age-related macular degeneration; angiography; antivascular endothelial growth factor therapy; choroidal neovascularization; geographic atrophy; multimodal imaging; ophthalmology; optical coherence tomography; photodynamic therapy; retinal pigment epithelium
(This special issue belongs to the Section Ophthalmology)
Recent Developments and Emerging Trends in Aortic Surgery
edited by Daniele Linardi
submission deadline 28 May 2025 | 1 articles | Viewed by 1717 | Submission Open
Keywords: aortic aneurysm; aortic dissection; endovascular repair; minimally invasive approaches; thoracic aorta; abdominal aorta; aortic valve-sparing surgery; aortic stent grafts
(This special issue belongs to the Section Vascular Medicine)
New Advances in Myasthenia Gravis
edited by Shingo Konno
submission deadline 29 May 2025 | 2 articles | Viewed by 947 | Submission Open
Keywords: myasthenia gravis; clinical trials; translational research; drug repurposing; biological markers; experimental autoimmune myasthenia gravis
(This special issue belongs to the Section Clinical Neurology)
New Advances in the Management of Voice Disorders submission deadline 30 May 2025 | 12 articles | Viewed by 22772 | Submission Open
Keywords: voice disorder; voice treatment/therapy; voice assessment/measures; laryngology; phonosurgery; voice/dysphonia; larynx
(This special issue belongs to the Section Otolaryngology)
Dry Eye Disease: Risk Factors, Diagnosis, Treatment and Prevention Measures
edited by and Jennifer P. Craig
submission deadline 30 May 2025 | 13 articles | Viewed by 21430 | Submission Open
Keywords: dry eye disease; meibomian gland dysfunction; epidemiology; diagnosis; management; risk factors
(This special issue belongs to the Section Ophthalmology)
Management of Heart Failure
edited by , and Dragos Cozma
submission deadline 30 May 2025 | 3 articles | Viewed by 19616 | Submission Open
Keywords: heart failure; revascularization; device implantation; resynchronization therapy; implantable cardiac defibrillator; contractility modulation; mitra-clip; telemedicine
(This special issue belongs to the Section Cardiology)
Kidney Transplantation: Current Challenges and Future Perspectives
edited by Alberto Piana and Angelo Territo
submission deadline 30 May 2025 | 11 articles | Viewed by 16802 | Submission Open
Keywords: kidney transplantation; urologic cancers; organ preservation; surgical challenges; donor selection; long-term out-comes; complications; post-transplant care; technology
(This special issue belongs to the Section Nephrology & Urology)
Recent Advances in Endocrine Surgery
edited by
submission deadline 30 May 2025 | 5 articles | Viewed by 8539 | Submission Open
Keywords: endocrine surgery; thyroid; thyroid cancer; parathyroid; parathyroidectomy; adrenal glands; disorders of hepatobiliary and gastrointestinal tract
(This special issue belongs to the Section General Surgery)
Pruritus and Psyche: An Update on Clinical Management
edited by Simon M. Mueller and Antonios Kolios
submission deadline 30 May 2025 | 6 articles | Viewed by 7901 | Submission Open
Keywords: pruritus; itching; psyche; psychodermatology; psychopharmacology; modern treatment; burden of disease; depression; anxiety; stress; delusional infestation; skin– brain axis
(This special issue belongs to the Section Dermatology)
Trends in Plastic and Reconstructive Surgery
edited by Eduardo D. Rodriguez, Carter J. Boyd and Oriana D. Cohen
submission deadline 30 May 2025 | 2 articles | Viewed by 5407 | Submission Open
Keywords: plastic surgery; innovation; breast surgery; microsurgery; craniofacial surgery; hand surgery; body contouring
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Urological Oncology: New Insights into Diagnosis and Treatment
edited by Aldo Brassetti
submission deadline 30 May 2025 | 3 articles | Viewed by 5360 | Submission Open
Keywords: minimally invasive surgical procedures; robotic surgical procedures; laparoscopy; augmented reality; prostatectomy; nephrectomy; cystectomy; diagnosis; immunotherapy; chemotherapy
(This special issue belongs to the Section Nephrology & Urology)
Clinical Management of Palliative Medicine submission deadline 30 May 2025 | 4 articles | Viewed by 5206 | Submission Open
Keywords: advance care planning; death; ethics; hospice care; pain management; palliative care; psychosocial functioning
(This special issue belongs to the Section Oncology)
Gastrointestinal Endoscopy: Recent Developments and Emerging Trends
edited by and Nico Pagano
submission deadline 30 May 2025 | 3 articles | Viewed by 4460 | Submission Open
Keywords: interventional ultrasonography; endoscopy; gastrointestinal endoscopy; NET; pancreatic cancer; EUS; endo-hepatology; ERCP
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Advancements in Cornea Transplantation
edited by Giulia Coco and Davide Romano
submission deadline 30 May 2025 | 5 articles | Viewed by 4247 | Submission Open
Keywords: corneal transplant; keratoplasty; DMEK; DSAEK; PK; cornea
(This special issue belongs to the Section Ophthalmology)
Perinatal Mental Health Management submission deadline 30 May 2025 | 3 articles | Viewed by 4000 | Submission Open
Keywords: perinatal mental health; child mental health; problem behavior; cognitive development therapy; hyperactivity
(This special issue belongs to the Section Mental Health)
Pelvic Organ Prolapse: Current Progress and Clinical Challenges
edited by and Cosimo De Nunzio
submission deadline 30 May 2025 | 3 articles | Viewed by 3819 | Submission Open
Keywords: pelvic organ prolapse (POP); postmenopausal; urinary dysfunction; minimally invasive surgery; laparoscopic surgery; robotic surgery; surgical mesh
(This special issue belongs to the Section Obstetrics & Gynecology)
Aortic Pathologies: Aneurysm, Atherosclerosis and More
edited by Alexander Gombert and Panagiotis Doukas
submission deadline 30 May 2025 | 4 articles | Viewed by 3556 | Submission Open
Keywords: aorta; aortic aneurysm; thoracoabdominal aortic aneurysm; fenestrated endovascular aortic repair (FEVAR); branched endovascular aortic repair (BEVAR); spinal cord ischemia; coral reef aorta; surgery; endovascular aortic surgery
(This special issue belongs to the Section Cardiovascular Medicine)
Personalized Risk Stratification with Diagnostic and Prognostic Relevance for Coronary Artery Disease: New Challenges and Opportunities in a New Era submission deadline 30 May 2025 | 3 articles | Viewed by 3474 | Submission Open
Keywords: coronary artery disease; cardiovascular prevention; risk stratification; cardiovascular pathology
(This special issue belongs to the Section Cardiovascular Medicine)
Clinical Advances in Spine Disorders submission deadline 30 May 2025 | 3 articles | Viewed by 3129 | Submission Open
Keywords: spine disorders; lumbar spine surgery; minimally invasive surgery; spine surgery; microneurosurgery
(This special issue belongs to the Section Clinical Neurology)
Coronary Heart Disease: Causes, Diagnosis and Management
edited by
submission deadline 30 May 2025 | 2 articles | Viewed by 2438 | Submission Open
Keywords: coronary heart disease; coronary revascularization; coronary artery disease; ischemic heart disease; atherosclerosis
(This special issue belongs to the Section Cardiology)
Current Perspectives on the Management of Atrial Fibrillation
edited by Narut Prasitlumkum and Nithi Tokavanich
submission deadline 30 May 2025 | 1 articles | Viewed by 2058 | Submission Open
Keywords: atrial fibrillation; management; AF ablation; anticoagulation; left atrial appendage ligation/occlusion; same-day discharge
(This special issue belongs to the Section Cardiology)
Clinical Utility of Optical Coherence Tomography in Ophthalmology: 2nd Edition submission deadline 30 May 2025 | 1 articles | Viewed by 1623 | Submission Open
Keywords: optical coherence tomography; ophthalmology; intraoperative OCT; en face OCT; wide-field OCT; retinal diseases; glaucoma; cornea; strabismus; cataract
(This special issue belongs to the Section Ophthalmology)
Current State of Breast Reconstruction
edited by
submission deadline 30 May 2025 | 1 articles | Viewed by 1419 | Submission Open
Keywords: breast reconstruction; silicone implant; autologous tissue; acellular dermal matrix; seroma; outcome; complication; patient satisfaction
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Mitral and Tricuspid Valve Disease and Imaging Techniques—2nd Edition
edited by and Annalisa Pasquini
submission deadline 30 May 2025 | 2 articles | Viewed by 1351 | Submission Open
Keywords: imaging in valvular heart disease; mitral valve disease; tricuspid valve disease; computed tomography; echocardiography; transesophageal echocardiography; cardiac magnetic resonance imaging; cardiac surgery; structural interventional cardiology; multi-modality imaging
(This special issue belongs to the Section Cardiovascular Medicine)
Breast Reconstruction: The Current Environment and Future Directions
edited by Chris A. Campbell
submission deadline 30 May 2025 | 2 articles | Viewed by 1289 | Submission Open
Keywords: breast reconstruction; plastic surgery; microsurgery; trunk and extremity reconstruction; cancer resection; head and neck reconstruction
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Personalized Therapy and Clinical Advances for Congenital Heart Disease submission deadline 30 May 2025 | 1 articles | Viewed by 1201 | Submission Open
Keywords: congenital heart disease; genetics; inheritance; biochemical; behavioral; lifestyle; artificial intelligence
(This special issue belongs to the Section Cardiology)
Neural Application of Artificial Intelligence in Clinical Neuroscience
edited by Saurabh J. Singhal
submission deadline 30 May 2025 | 1 articles | Viewed by 1135 | Submission Open
Keywords: artificial intelligence (AI); clinical neuroscience; neuroimaging; brain– computer interfaces (BCIs); neuroprosthetics; EEG/EMG analysis; robotic surgery; deep brain stimulation (DBS); drug discovery; telemedicine; neurorehabilitation; stroke detection; Alzheimer’ s disease; brain tumors; seizure prediction
(This special issue belongs to the Section Clinical Neurology)
Spine Surgery: Clinical Advances and Future Directions
edited by and Eun-Sang Kim
submission deadline 30 May 2025 | 1 articles | Viewed by 1107 | Submission Open
Keywords: spine surgery; back pain; endoscopic spine surgery; cage implantation; neck pain
(This special issue belongs to the Section Clinical Neurology)
Latest Advances in Glaucoma, Cataract and Refractive Surgery: Expert Views, 2nd Edition submission deadline 30 May 2025 | 1 articles | Viewed by 910 | Submission Open
Keywords: refractive surgery; glaucoma; cataract; intraocular lenses; diagnostic imaging
(This special issue belongs to the Section Ophthalmology)
Aortic Valve Implantation: Recent Advances and Future Prospects
edited by Suvitesh Luthra and Richard Jabbour
submission deadline 30 May 2025 | Viewed by 330 | Submission Open
Keywords: aortic valve replacement; aortic stenosis; paravalvular leak; coronary and structural interventional cardiology; percutaneous coronary artery interventions
(This special issue belongs to the Section Cardiology)
Rheumatoid Arthritis: Challenges, Innovations and Outcomes
edited by
submission deadline 30 May 2025 | Viewed by 329 | Submission Open
Keywords: rheumatoid arthritis; pathogenesis; treatments; outcomes; autoimmunity
(This special issue belongs to the Section Immunology)
Multiple Sclerosis and Demyelinating Disorders: Past, Present, and Future—2nd Edition submission deadline 30 May 2025 | Viewed by 295 | Submission Open
Keywords: multiple sclerosis; disease-modifying therapies; neurodegeneration; neuromyelitis optica; disease monitoring; diagnostic criteria
(This special issue belongs to the Section Clinical Neurology)
Blood Cancer: Current Status and Future Challenges in Acute Myeloid Leukemia (AML)
edited by and Massimo Breccia
submission deadline 30 May 2025 | Viewed by 276 | Submission Open
Keywords: acute myeloid leukemia; hematology; leukemia; venetoclax; blood disorders
(This special issue belongs to the Section Hematology)
New Frontiers and Technologies in Spine Surgery
edited by
submission deadline 30 May 2025 | Viewed by 195 | Submission Open
Keywords: spine; technologies; future; surgery; innovations; mini-invasive surgery
(This special issue belongs to the Section Clinical Neurology)
Hospital-Acquired Infections in the Elderly
edited by Nadya Kagansky and Emily Lubart
submission deadline 30 May 2025 | Viewed by 186 | Submission Open
Keywords: hospital-acquired infections (HAIs); elderly patients; infection control; microbial resistance; epidemiology; risk factors; prevention strategies; treatment options; diagnostic accuracy
(This special issue belongs to the Section Epidemiology & Public Health)
Challenges in Fertility Preservation
edited by and Guido Ambrosini
submission deadline 30 May 2025 | Viewed by 184 | Submission Open
Keywords: fertility preservation; oocytes cryopreservation; embryo cryopreservation; ovarian tissue transplantation; gonadotoxic therapy
(This special issue belongs to the Section Reproductive Medicine & Andrology)
Multiple Myeloma: Therapeutic and Management Strategies
edited by Terri Parker
submission deadline 30 May 2025 | Viewed by 151 | Submission Open
Keywords: multiple myeloma; frontline treatment; monoclonal antibodies; sequencing of treatment; immunotherapy; CAR T; Bi-specific T cell engagers; toxicity management
(This special issue belongs to the Section Hematology)
Clinical Advancements in Urologic Surgery
edited by Francesco Trama
submission deadline 30 May 2025 | Viewed by 135 | Submission Open
Keywords: urologic oncology; urinary incontinence; endourology; urodynamics; prostate cancer; neurourology; erectile dysfunction
(This special issue belongs to the Section Nephrology & Urology)
Recent Advances in Trauma and Orthopaedic Surgery
edited by Konstantinos Tsikopoulos and
submission deadline 31 May 2025 | 8 articles | Viewed by 13251 | Submission Open
Keywords: trauma; orthopaedic surgery; clinical research; orthopaedics; infection orthopaedic
(This special issue belongs to the Section Orthopedics)
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