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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Preoperative Optimization in Cardiac Surgery

edited by

Jason M. Ali

submission deadline 31 Oct 2025 | Viewed by 166 | Submission Open

Keywords: preoperative optimization; cardiac surgery; risk assessment; comorbid conditions; multidisciplinary collaboration; perioperative risks; cardiovascular evaluation

(This special issue belongs to the Section Cardiology)

Recent Advances in the Epidemiology of Infectious Diseases: A Clinical Perspective

edited by

Yazan A. Al-Ajlouni

submission deadline 31 Oct 2025 | Viewed by 152 | Submission Open

Keywords: epidemiology of infectious diseases; global health and infectious diseases; hospital-acquired infections (HAIs); infection control; novel treatments; vaccine effectiveness

(This special issue belongs to the Section Epidemiology & Public Health)

Current Challenges and Innovations in Spine Deformity: Biomechanics, Imaging and AI-Driven Analysis

edited by Dong-Ho Kang

submission deadline 31 Oct 2025 | Viewed by 147 | Submission Open

Keywords: spinal deformity; cervical deformity; biomechanics; postural alignment; sagittal imbalance; medical imaging; radiographic analysis; artificial intelligence; machine learning; deep learning; phenotyping; computer-assisted diagnosis; predictive modeling; surgical planning

(This special issue belongs to the Section Orthopedics)

Immunotherapy of Hematological Malignancies: The State of the Art

edited by

Anca Colita

and

Romeo Gabriel Mihaila

submission deadline 31 Oct 2025 | Viewed by 147 | Submission Open

Keywords: antibody-drug conjugates; bispecific antibodies; chimeric antigen receptor-engineered natural killer cell; chimeric antigen receptor T-cells; cytokine release syndrome; immune checkpoint in-hibitors; immunosuppression; immunotherapy; monoclonal antibodies; neurotoxicities

(This special issue belongs to the Section Hematology)

Takotsubo Syndrome: Insights into Pathophysiology, Diagnosis, and Management

edited by

Andreas Mitsis

and

Nikolaos Kadoglou

submission deadline 31 Oct 2025 | Viewed by 136 | Submission Open

Keywords: takotsubo syndrome; stress cardiomyopathy; acute heart failure; cardiac imaging; catecholamine surge; myocardial dysfunction; echocardiography; biomarker discovery; cardiovascular risk; clinical management

(This special issue belongs to the Section Cardiology)

Intramedullary Nail of Long Bone Fractures: Treatments, Outcomes, and Staying out of Trouble

edited by Robert D. Zura and Jessica C. Rivera

submission deadline 31 Oct 2025 | Viewed by 133 | Submission Open

Keywords: intramedullary nail; intramedullary fixation; fracture fixation; femur fracture; tibia fracture; orthopedic implant; fracture healing

(This special issue belongs to the Section Orthopedics)

Recent Developments in Reproductive Endocrinology

edited by Birute Žilaitiené and Jonas Čeponis

submission deadline 31 Oct 2025 | Viewed by 132 | Submission Open

Keywords: hypogonadism; infertility; sex hormone deficiency; reproductive endocrinology; sexual health; assisted reproduction

(This special issue belongs to the Section Endocrinology & Metabolism)

Updates in Diabetes and Obesity in Reproductive Health

edited by

Amihai Rottenstreich

and Giulia Barda

submission deadline 31 Oct 2025 | Viewed by 129 | Submission Open

Keywords: obesity; diabetes; reproductive health; childbearing age; pregnancy

(This special issue belongs to the Section Reproductive Medicine & Andrology)

New Developments in Coronary Interventional Therapy

edited by

Chadi Alraies

submission deadline 31 Oct 2025 | Viewed by 122 | Submission Open

Keywords: high risk PCI; optical coherence tomography; chronic total occlusions; bifurcation lesions; left main stem disease; multivessel coronary artery disease

(This special issue belongs to the Section Cardiology)

Skin Cancers: Update on Clinical Treatment and Management

edited by Nazzaro Gianluca

submission deadline 31 Oct 2025 | Viewed by 120 | Submission Open

Keywords: basal cell carcinoma; squamous cell carcinoma; melanoma; skin cancers; dermoscopy; ultrasonography; immunotherapy; biomarker; prevention; diagnosis; treatment; innovative treatments; prognosis

(This special issue belongs to the Section Dermatology)

Neuropathic Pain: From Prevention to Diagnosis and Management

edited by Enrico Martin

submission deadline 31 Oct 2025 | Viewed by 117 | Submission Open

Keywords: neuropathic pain; clinical research; TMR; RPNI; preclinical studies; QoL; PROMS; translational medicine; pain mechanisms

(This special issue belongs to the Section Clinical Neurology)

Urologic Neoplasms: Recent Advances and Future Perspectives

edited by

Dorit E. Zilberman

submission deadline 31 Oct 2025 | Viewed by 109 | Submission Open

Keywords: robotic surgery; laparoscopic surgery; immunotherapy; chemotherapy; radiotherapy; prostate cancer; renal cancer; bladder cancer; upper urinary tract neoplasm; testicular cancer; penile cancer

(This special issue belongs to the Section Oncology)

Challenges and Opportunities in Bariatric Surgery

edited by

Francisco Guzman Pruneda

and Umashankkar Kannan

submission deadline 31 Oct 2025 | Viewed by 102 | Submission Open

Keywords: bariatric surgery; DVT/VTE; bleeding; complications; prophylaxis

(This special issue belongs to the Section General Surgery)

PET/CT Imaging in Oncology: Clinical Updates and Prospects

edited by Ahmad Shariftabrizi

submission deadline 5 Nov 2025 | 1 articles | Viewed by 400 | Submission Open

Keywords: new radiotracers; PET radiomics; CAR T-cell therapy; rare tumors; radiogenomics; immunotherapy outcome prediction; PET physics; normal tissue PET/CT; synchronous malignancies

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Rehabilitation Medicine and Clinical Research: From Diagnosis to Therapeutic Interventions

edited by

Yazan A. Al-Ajlouni

submission deadline 6 Nov 2025 | Viewed by 216 | Submission Open

Keywords: rehabilitation medicine; clinical research; therapeutic interventions; diagnosis; physical therapy; occupational therapy; neurorehabilitation; musculoskeletal rehabilitation; cardiac rehabilitation; functional recovery; assistive technologies; patient-centered care; outcome measures; rehabilitation innovations; multidisciplinary approaches

(This special issue belongs to the Section Clinical Rehabilitation)

Potential Cures of Alzheimer's Dementia

edited by

Jeffrey Fessel

submission deadline 10 Nov 2025 | 4 articles | Viewed by 13654 | Submission Open

Keywords: Alzheimer’ s dementia; cure; therapeutic approaches; clinical assessment; diagnosis; treatment

(This special issue belongs to the Section Mental Health)

New Insights into Exercise Intervention for Aging and Geriatric Diseases: 2nd Edition

edited by

Hyuntae Park

submission deadline 10 Nov 2025 | 6 articles | Viewed by 8877 | Submission Open

Keywords: exercise intervention; exercise adherence and feasibility; digital exercise therapy; digital therapeutics; mild cognitive impairment; osteoporosis; dementia; sarcopenia; frailty; depression; sleep disorder; obesity; geriatric disease

(This special issue belongs to the Section Sports Medicine)

Neuro-Psychiatric Disorders: Updates on Diagnosis and Treatment

edited by

Georgios Floros

submission deadline 10 Nov 2025 | 4 articles | Viewed by 6714 | Submission Open

Keywords: neuropsychiatric disorder; diagnosis; treatment; neurobiology; organic psychiatry

(This special issue belongs to the Section Mental Health)

Gastroesophageal Cancer: Advances in Clinical Diagnosis and Management

edited by

Tania Triantafyllou

and Maximos Frountzas

submission deadline 10 Nov 2025 | 4 articles | Viewed by 3352 | Submission Open

Keywords: gastroesophageal cancer; endoscopic therapy; minimally invasive surgery; multimodality treatment; immunotherapy

(This special issue belongs to the Section Oncology)

Clinical Advances in Trauma and Emergency Medicine

edited by Viktoria Bogner-Flatz

submission deadline 10 Nov 2025 | 4 articles | Viewed by 2745 | Submission Open

Keywords: resuscitation; trauma emergency management; disaster response; mild traumatic brain injury emergency management; critical emergency care

(This special issue belongs to the Section Emergency Medicine)

Pediatric Neuromuscular Diseases: Current Concepts, Challenges and Opportunities (Second Edition)

edited by Nina Barišić

submission deadline 10 Nov 2025 | Viewed by 156 | Submission Open

Keywords: neuromuscular disorders (NMD); pediatric; genetic NMD; chronic demyelinating polyneuropathy; juvenile myasthenia gravis; ethics; health economics; next generation sequencing (NGS); diagnosis; prenatal; fetal; disease modifying therapy; immunotherapy; guidelines

(This special issue belongs to the Section Clinical Pediatrics)

New Advances in Myasthenia Gravis

edited by Shingo Konno

submission deadline 13 Nov 2025 | 3 articles | Viewed by 1914 | Submission Open

Keywords: myasthenia gravis; clinical trials; translational research; drug repurposing; biological markers; experimental autoimmune myasthenia gravis

(This special issue belongs to the Section Clinical Neurology)

Clinical Advances in Cardiovascular Interventions

edited by

Tomasz Tokarek

submission deadline 14 Nov 2025 | 8 articles | Viewed by 6533 | Submission Open

Keywords: coronary artery disease; myocardial infarction; cardiovascular imaging; microvascular disease; heart failure; atrial fibrillation; ventricular arrhythmias; cardiac implantable electronic device; valvular heart disease and treatment; peripheral arterial disease

(This special issue belongs to the Section Cardiology)

New Advances in Wound Healing and Skin Wound Treatment

edited by Hajime Matsumura

submission deadline 15 Nov 2025 | 2 articles | Viewed by 2329 | Submission Open

Keywords: trauma wound; burns; chronic wound; DFU; VLU; ischemic wound; regenerative medicine in wound care; debridement; biofilm; wound dressing; antimicrobial treatment

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Advances in Catheter Ablation: Current Challenges and Future Perspectives

edited by

Gabriel Cismaru

and Raluca Tomoaia

submission deadline 15 Nov 2025 | 2 articles | Viewed by 2325 | Submission Open

Keywords: catheter ablation; three-dimensional mapping; arrhythmia; wolf– parkinson– white syndrome; atrial fibrillation

(This special issue belongs to the Section Cardiology)

Clinical Applications of Artificial Intelligence (AI) in Surgery: Future Trends and Challenges

edited by

Michał H. Strzelecki

and

Rafał Obuchowicz

submission deadline 15 Nov 2025 | 1 articles | Viewed by 914 | Submission Open

Keywords: artificial intelligence; surgical planning; surgical medical robots; machine learning in surgery; AI-supported post-operative care

(This special issue belongs to the Section General Surgery)

Clinical Update in Pulmonary Rehabilitation

edited by Akira Tamaki

submission deadline 15 Nov 2025 | Viewed by 154 | Submission Open

Keywords: pulmonary rehabilitation; chronic obstructive pulmonary disease; interstitial lung disease; sarcopenia; respiratory sarcopenia; respiratory muscle training; nutritional intervention

(This special issue belongs to the Section Respiratory Medicine)

Neuroendocrine Neoplasms: Epidemiology, Clinical Management, and Emerging Therapies

edited by

H. Christian Weber

submission deadline 15 Nov 2025 | Viewed by 124 | Submission Open

Keywords: neuroendocrine neoplasms (NENs); epidemiology; biomarkers for NENs; targeted therapies for NENs; carcinoid syndrome; precision medicine; gastrointestinal NENs; advanced endoscopic approaches to NEN treatment; imaging modalities for NENs; survival risk factors in NENs

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Mechanisms and Management of Intracerebral Hemorrhage

edited by Emanuela Crobeddu

submission deadline 15 Nov 2025 | Viewed by 70 | Submission Open

Keywords: intracerebral hemorrhage; arteriovenous malformation (AVM); dural arteriovenous fistula (DAVF); cavernoma; neuroinflammation; blood– brain barrier; hematoma evacuation; neuroprotection; imaging technologies; vascular lesions

(This special issue belongs to the Section Clinical Neurology)

Clinical Advances in Vascular and Endovascular Surgery

edited by Toshifumi Kudo

submission deadline 20 Nov 2025 | 11 articles | Viewed by 13250 | Submission Open

Keywords: aortic aneurysm; peripheral arterial disease; chronic limb-threatening ischemia; endovascular aneurysm repair; endovascular treatment; non-invasive blood flow measurements; varicose veins; deep venous thrombosis

(This special issue belongs to the Section Vascular Medicine)

Advances in Trauma and Orthopedic Surgery: 2nd Edition

edited by

Christian von Rüden

submission deadline 20 Nov 2025 | 10 articles | Viewed by 11421 | Submission Open

Keywords: trauma; fracture; fracture fixation; osteosynthesis; biomechanics; bone; approach; nonunion; joint replacement; outcome

(This special issue belongs to the Section Orthopedics)

Thromboembolic Disease and Antithrombotic Therapy

edited by Prahlad Ho

submission deadline 20 Nov 2025 | 6 articles | Viewed by 10549 | Submission Open

Keywords: thrombosis; pulmonary embolism; manticoagulation; DOAC (direct oral anticoagulants); DVT (deep vein thrombosis); novel anticoagulants (factor XIa inhibitors); thrombin; fibrin generation; risk stratification; biomarkers; Virchow’ s triad; post thrombotic syndrome

(This special issue belongs to the Section Hematology)

Association Between Sleep Disorders and Diabetes

edited by

Patrizio Tatti

and Desiderio Passàli

submission deadline 20 Nov 2025 | 2 articles | Viewed by 9925 | Submission Open

Keywords: diabetes; OSAS; complications; insulin; resistance

(This special issue belongs to the Section Endocrinology & Metabolism)

Hypertension in Adults: Current Updates on Diagnosis, Treatment and Management

edited by Emelina Stambolliu and Antonios A. Argyris

submission deadline 20 Nov 2025 | 5 articles | Viewed by 8590 | Submission Open

Keywords: essential hypertension; nighttime blood pressure; blood pressure measurement; blood pressure management; blood pressure medical treatment; hypertension thresholds

(This special issue belongs to the Section Vascular Medicine)

Complex Orthopedic Trauma: Diagnosis, Treatment, Managing Complications and Rehabilitation

edited by Philip-Christian Nolte and Benedict Swartman

submission deadline 20 Nov 2025 | 5 articles | Viewed by 5768 | Submission Open

Keywords: orthopedic trauma; fracture; complications; infection; bone; rehabilitation

(This special issue belongs to the Section Orthopedics)

Advances in Clinical Practice and Personalized Approaches in Cardiovascular Disease

edited by Joseph B. Selvanayagam and

Sivabaskari Pasupathy

submission deadline 20 Nov 2025 | 6 articles | Viewed by 5669 | Submission Open

Keywords: personalized medicine; cardiovascular innovations; cardiac imaging; risk assessment; multimodal imaging; therapeutic strategies; data-driven decision making; clinical outcomes; translational research

(This special issue belongs to the Section Cardiovascular Medicine)

Cardiovascular Disease in the Elderly: Prevention and Diagnosis

edited by Ioana Dana Alexa, Gabriel Ioan Prada and

Ciprian Rezus

submission deadline 20 Nov 2025 | 6 articles | Viewed by 4690 | Submission Open

Keywords: cardiovascular risk factors; elderly patients; frailty; sarcopenia; heart rate variability; insulin resistance; physical resilience; intrinsic capacity; diastolic dysfunction

(This special issue belongs to the Section Cardiovascular Medicine)

Pelvic Organ Prolapse: Current Progress and Clinical Challenges

edited by

Riccardo Lombardo

and Cosimo De Nunzio

submission deadline 20 Nov 2025 | 3 articles | Viewed by 4610 | Submission Open

Keywords: pelvic organ prolapse (POP); postmenopausal; urinary dysfunction; minimally invasive surgery; laparoscopic surgery; robotic surgery; surgical mesh

(This special issue belongs to the Section Obstetrics & Gynecology)

Clinical Research of Novel Therapeutic Approaches in Dentistry (2nd Edition)

edited by

Jacek Matys

Kinga Grzech-Lesniak

and

Tomasz Gedrange

submission deadline 20 Nov 2025 | 5 articles | Viewed by 4361 | Submission Open

Keywords: oral medicine; tissue regeneration; lasers; photobiomodulation; periodontology; dentistry; biological safety

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Sports Injury Treatment: Innovations in Pain Management, Recovery, and Performance Optimization

edited by Antonio P. Veloso and Javad Sarvestan

submission deadline 20 Nov 2025 | 2 articles | Viewed by 4239 | Submission Open

Keywords: sports injury treatment; pain management; recovery optimization; performance enhancement; advanced rehabilitation; injury prevention; biomechanics; neuromechanics; novel pain relief modalities; performance recovery strategies; wearable technology

(This special issue belongs to the Section Sports Medicine)

The Association Between Sleep Disorders and Metabolic and Mental Health

edited by

Filip Franciszek Karuga

Piotr Bialasiewicz

and

Marcin Sochal

submission deadline 20 Nov 2025 | 3 articles | Viewed by 4003 | Submission Open

Keywords: sleep medicine; sleep apnea; hypoxia; metabolism; mental health; women’ s health

(This special issue belongs to the Section Mental Health)

New Clinical Advances in Chronic Asthma

edited by Vitaliano Nicola Quaranta

submission deadline 20 Nov 2025 | 3 articles | Viewed by 3316 | Submission Open

Keywords: chronic asthma; breathlessness; coughing; inhaled corticosteroids (ICS); long-acting beta-agonists (LABAs); personalized treatment; chronic rhinosinusitis; nasal polyps; bronchiectasis; endotypes; oral corticosteroids

(This special issue belongs to the Section Respiratory Medicine)

Advances in the Diagnosis and Treatment of Heart Failure

edited by

Noel Lorenzo-Villalba

and

Manuel Montero-Perez-Barquero

submission deadline 20 Nov 2025 | 3 articles | Viewed by 3177 | Submission Open

Keywords: heart failure; diagnosis; treatment; elderly; pluripathology

(This special issue belongs to the Section Cardiology)

Clinical Advances in Orthopedic Infections

edited by

Hyonmin Choe

submission deadline 20 Nov 2025 | 2 articles | Viewed by 2436 | Submission Open

Keywords: orthopedic surgery; orthopedic infections; periprosthetic joint infection; surgical site infection; infection management

(This special issue belongs to the Section Orthopedics)

Current State of Breast Reconstruction

edited by

Il-Kug Kim

submission deadline 20 Nov 2025 | 2 articles | Viewed by 2332 | Submission Open

Keywords: breast reconstruction; silicone implant; autologous tissue; acellular dermal matrix; seroma; outcome; complication; patient satisfaction

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Updates on Cardiac Pacing and Electrophysiology

edited by

Axel Brandes

submission deadline 20 Nov 2025 | 2 articles | Viewed by 2144 | Submission Open

Keywords: pacemaker; conduction system pacing; leadless pacemaker; implantable cardioverter– defibrillator; ICD; extravascular ICD; S-ICD; lead extraction; supraventricular tachycardia; ventricular tachycardia; cardio-neuro ablation

(This special issue belongs to the Section Cardiology)

PET Imaging in Bone and Non-Bone Diseases

edited by

Tanuj Puri

and

Glen Blake

submission deadline 20 Nov 2025 | 2 articles | Viewed by 1880 | Submission Open

Keywords: PET; bone metabolism; bone diseases; metabolic bone diseases; image analysis; radiomics; artificial intelligence

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Cardiopulmonary Resuscitation—from Research to Clinical Implementation

edited by

Endre Zima

submission deadline 20 Nov 2025 | 3 articles | Viewed by 1836 | Submission Open

Keywords: cardiopulmonary resuscitation; cardiac arrest; basic life support; advanced life support; special circumstances; target temperature management; eCPR-ECLS; survival

(This special issue belongs to the Section Emergency Medicine)

Clinical Updates in Lung Ultrasound

edited by

Lior Fuchs

submission deadline 20 Nov 2025 | 1 articles | Viewed by 1726 | Submission Open

Keywords: lung ultrasound; intensive care; imaging; ARDS; POCUS

(This special issue belongs to the Section Respiratory Medicine)

Clinical Perspectives in Reconstructive Urethral Surgery

edited by Krishnan Venkatesan

submission deadline 20 Nov 2025 | 2 articles | Viewed by 1720 | Submission Open

Keywords: urethral reconstruction; urethroplasty; urethral stricture; bladder neck stenosis; urinary fistula

(This special issue belongs to the Section Nephrology & Urology)

Displaying special issue 701-750 on page 15 of 28.

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