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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Interventional Cardiology: Evolving Evidence and Emerging Horizons

edited by

Jacek Bil

submission deadline 31 Jul 2026 | Viewed by 8 | Submission Open

Keywords: coronary artery disease; percutaneous coronary intervention; drug-coated balloon; intravascular imaging; fractional flow reserve; transcatheter aortic valve implantation; transcatheter mitral valve repair; clinical outcomes

(This special issue belongs to the Section Cardiology)

Sports Cardiology: Current Clinical Status and Outlook into the Future

edited by Aakash Bavishi and Matthew W Martinez

submission deadline 10 Aug 2026 | Viewed by 50 | Submission Open

Keywords: sports cardiology; athletes; cardiac imaging; hypertrophic cardiomyopathy; screening; electrocardiogram; electrophysiology; echocardiography; sudden cardiac death

(This special issue belongs to the Section Cardiology)

New Insights into Glaucoma: 2nd Edition

edited by

Su-Ho Lim

and

Daniel Laroche

submission deadline 10 Aug 2026 | Viewed by 29 | Submission Open

Keywords: glaucoma; intraocular pressure (IOP); risk calculators; glaucoma screening glaucoma surgery; cataract surgery; trabeculectomy; glaucoma drainage devices; minimally invasive glaucoma surgery (MIGS); artificial intelligence (AI)

(This special issue belongs to the Section Ophthalmology)

Neurovascular Canvas: From Basic Science to Clinical Breakthroughs

edited by

Ciro De Luca

, Nicola Giannini and

Alessandro Viganò

submission deadline 15 Aug 2026 | Viewed by 53 | Submission Open

Keywords: neurovascular unit (NVU); neurodegeneration; vascular biology; stroke; disease modeling

(This special issue belongs to the Section Clinical Neurology)

Spine Surgery: Novel Challenges and Opportunities

edited by

Tae-Hwan Kim

submission deadline 15 Aug 2026 | Viewed by 12 | Submission Open

Keywords: spine surgery; surgical outcomes; postoperative care; complications; epidemiology; diagnostic imaging; biomaterials; biomechanics; machine learning; artificial intelligence; predictive modeling; minimally invasive techniques; population-based studies; clinical decision-making

(This special issue belongs to the Section Orthopedics)

Advances in the Diagnosis and Management of Age-Related Macular Degeneration: 3rd Edition

edited by Tsutomu Yasukawa

submission deadline 20 Aug 2026 | Viewed by 129 | Submission Open

Keywords: age-related macular degeneration; angiography; anti-vascular endothelial growth factor therapy; geographic atrophy; macular neovascularization; multimodal imaging; ophthalmology; optical coherence tomography; photodynamic therapy; retinal pigment epithelium

(This special issue belongs to the Section Ophthalmology)

Current Trends and Innovations in Coronary Artery Disease and Myocardial Ischemia: Second Edition

edited by

Edoardo Conte

submission deadline 20 Aug 2026 | Viewed by 56 | Submission Open

Keywords: coronary artery disease; fractional flow reserve; invasive coronary angiography; cardiac CT; cardiac MRI

(This special issue belongs to the Section Cardiovascular Medicine)

New Insights into Gastrointestinal Surgery: Advances in Techniques and Treatment Approaches

edited by Gabriella Teresa Capolupo

submission deadline 20 Aug 2026 | Viewed by 45 | Submission Open

Keywords: gastroenterology; gastrointestinal surgery; colorectal surgery; robotic surgery; technologies; minimally invasive surgery

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Updates on Reproductive Endocrinology in Children and Adolescents

edited by

Charikleia Stefanaki

submission deadline 20 Aug 2026 | Viewed by 18 | Submission Open

Keywords: reproductive endocrinology; adolescents; male hypogonadism; female hypogonadism; reproductive metabolism; PCOS; POF; receptor abnormalities; menstrual cycle; transgender health; CAH; ovaries; gonads; hormones; sex development; amenorrhea; estrogen resistance; androgen resistance; teen pregnancy; oncology; preservation of fertility

(This special issue belongs to the Section Clinical Pediatrics)

Anterior Segment Disorders

edited by Itay Lavy and

Nir Erdinest

submission deadline 20 Aug 2026 | Viewed by 12 | Submission Open

Keywords: anterior segment disorders; corneal disease; cataract surgery; ocular surface disease; surgical outcomes; surgical techniques; artificial intelligence in diagnosis; diagnostic imaging; pharmacological and surgical interventions; refractive errors; anterior uveitis; keratitis; corneal ectasia; quality of life

(This special issue belongs to the Section Ophthalmology)

Physical Therapy in Musculoskeletal Disorders: Prevention, Diagnosis, Clinical Management and Treatment—2nd Edition

edited by

Rubén Cuesta-Barriuso

submission deadline 20 Aug 2026 | Viewed by 11 | Submission Open

Keywords: physical therapy; musculoskeletal disorders; prevention; diagnosis; clinical management; treatment

(This special issue belongs to the Section Clinical Rehabilitation)

Advances in the Management of Cervical Spine Trauma

edited by

Jong-Beom Park

and

Sung-kyu Kim

submission deadline 20 Aug 2026 | Viewed by 7 | Submission Open

Keywords: cervical spine trauma; cervical fracture; high cervical injury; subaxial injury; surgical management; occipitocervical fusion; C1 fracture; C2 fracture; spinal stability; trauma imaging; spinal cord injury; neurological outcome

(This special issue belongs to the Section Orthopedics)

Diagnosis and Clinical Management in Hematologic Oncology

edited by Sunil Lakhwani and José María Raya-Sánchez

submission deadline 20 Aug 2026 | Viewed by 5 | Submission Open

Keywords: hematologic malignancies; lymphoma; multiple myeloma; acute leukemia; myeloproliferative neoplasms; molecular diagnostics; targeted therapy; immunotherapy; prognostic biomarkers; clinical management

(This special issue belongs to the Section Hematology)

Precision Neuroimaging in Mental and Behavioral Health Research

edited by Thomas Vanicek and Arkadiusz Komorowski

submission deadline 20 Aug 2026 | Viewed by 4 | Submission Open

Keywords: psychiatry; neuroimaging; addiction; substance use disorders (SUD); attention deficit hyperactivity disorder (ADHD); imaging genomics; imaging transcriptomics

(This special issue belongs to the Section Mental Health)

Clinical Advances in Orthopedic Infections: 2nd Edition

edited by

Hyonmin Choe

submission deadline 20 Aug 2026 | Submission Open

Keywords: orthopedic surgery; orthopedic infections; periprosthetic joint infection; surgical site infection; infection management

(This special issue belongs to the Section Orthopedics)

Clinical Outcomes of Glaucoma Surgery: Visual Acuity, Effectiveness and Quality of Life

edited by

Gloria Roberti

and

Manuele Michelessi

submission deadline 21 Aug 2026 | Viewed by 6 | Submission Open

Keywords: glaucoma surgery; visual acuity; intraocular pressure; surgical outcomes; trabeculectomy; microinvasive glaucoma surgery; postoperative complications; functional vision

(This special issue belongs to the Section Ophthalmology)

Advancements in Cardiomyopathies: Diagnosis, Treatment and Management—2nd Edition

edited by

Cinzia Forleo

and

Maria Cristina Carella

submission deadline 24 Aug 2026 | Viewed by 11 | Submission Open

Keywords: cardiomyopathies; multimodality imaging; cardiac magnetic resonance; genetic testing; cardiogenetics; genetic cardiovascular disease; rare cardiovascular diseases; risk stratification; genotype– phenotype correlations; rare variant interpretation; arrhythmias

(This special issue belongs to the Section Cardiology)

Current and Emerging Strategies in Ischemic Stroke: Diagnosis, Treatment, and Prevention

edited by

Dougho Park

Hyoung Seop Kim

and

Jong Hun Kim

submission deadline 25 Aug 2026 | Viewed by 17 | Submission Open

Keywords: diagnosis; digital medicine; epidemiology; ischemic stroke; machine learning; neurorehabilitation; prevention; stroke imaging; treatment

(This special issue belongs to the Section Clinical Neurology)

Knee Arthroplasty: Recent Advances and Future Challenges

edited by Matteo Marullo

submission deadline 25 Aug 2026 | Submission Open

Keywords: knee arthroplasty; implant design; robotic surgery; revision surgery; biomechanics; clinical outcomes; perioperative care; fast-track surgery; digital orthopedics; partial knee replacement

(This special issue belongs to the Section Orthopedics)

Clinical Updates in Heart Failure: Innovations in Diagnosis, Therapy and Management

edited by Paolo Severino

submission deadline 28 Aug 2026 | Viewed by 8 | Submission Open

Keywords: heart failure; HFrEF therapy; HFpEF phenotyping; right ventricular dysfunction; renal congestion assessment; diuretic resistance; NT-proBNP dynamics; cardiac imaging; post-discharge management

(This special issue belongs to the Section Cardiology)

Optimizing the Surgical Journey: From Abdominal Operation to Recovery

edited by

Alessio Giordano

and Carlo Bergamini

submission deadline 1 Sep 2026 | Viewed by 22 | Submission Open

Keywords: surgical complications; comanagement; comorbidities; elective surgical procedure; emergency surgery procedure; multidisciplinary approach; hospitalist

(This special issue belongs to the Section General Surgery)

Current Challenges in Clinical Dentistry: 3rd Edition

edited by

Eiji Tanaka

and

Susumu Abe

submission deadline 15 Sep 2026 | Viewed by 25 | Submission Open

Keywords: artificial intelligence; clinical dentistry; cutting-edge device and technology; dental material; challenging hypothesis; preventive dentistry; sleep medicine; digital dentistry; smart dentistry; stomatognathic function

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Treatment and Clinical Management of Necrotizing Pancreatitis

edited by

Apostolos Gaitanidis

submission deadline 20 Sep 2026 | Viewed by 29 | Submission Open

Keywords: necrotizing pancreatitis; infected necrosis; step-up approach; necrosectomy; minimally invasive surgery; artificial intelligence; lumen-apposing metal stent; pancreatic necrosis

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Management in Dry Eye Disease: Current Strategies and Emerging Protocols

edited by Sunil Shah and Raquel Gil-Cazorla

submission deadline 20 Sep 2026 | Viewed by 16 | Submission Open

Keywords: dry eye disease; ocular surface; diagnostics; inflammation; biomarkers; emerging therapies

(This special issue belongs to the Section Ophthalmology)

Advances in the Diagnosis and Management of Sarcoidosis

edited by

Carlos Feijoo-Massó

, Pilar Brito-Zerón and Miriam Akasbi Montalvo

submission deadline 25 Sep 2026 | Viewed by 10 | Submission Open

Keywords: sarcoidosis; diagnosis; biomarkers; imaging; immunopathogenesis; biologic therapy; prognosis; interstitial lung disease

(This special issue belongs to the Section Immunology & Rheumatology)

Fibromyalgia: Diagnostic Progress and Therapeutic Advances

edited by

Casandra Isabel Montoro Aguilar

submission deadline 17 Nov 2026 | Viewed by 38 | Submission Open

Keywords: fibromyalgia; chronic pain; central sensitization; diagnostic biomarkers; advanced imaging; molecular markers; autonomic nervous system; cardiovascular regulation; emotional processing; cognitive dysfunction; fatigue; pain modulation; neuromodulation; tDCS

(This special issue belongs to the Section Clinical Neurology)

Dental Care: Oral and Systemic Disease Prevention: 2nd Edition

edited by

Kacper Nijakowski

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1445 | Submission Open

Keywords: oral health; oral diseases; oral manifestations; systemic diseases; oral care; dental prevention; dental caries; periodontal disease; oral medicine; dentistry; oral microbiome; salivary diagnostics; AI-assisted tools

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Aortic Diseases: Modern Strategies in Diagnosis, Management, and Prevention of Complications

edited by

Petroula N. Nana

, Tilo Kölbel and José Ignacio F. Torrealba

submission deadline 20 Jul 2027 | Viewed by 123 | Submission Open

Keywords: aortic aneurysm; aortic dissection; genetic aortic disease; acute aortic syndromes; endovascular repair; complica-tions; outcomes

(This special issue belongs to the Section Vascular Medicine)

Insights into Urological Surgery: Evolving Practices, Trends, and Emerging Challenges

edited by