Diagnosis and Management of Endometriosis and Uterine Fibroids

Dear Colleagues,

Endometriosis and uterine fibroids are the most frequent gynecological disorders of reproductive-aged women. Endometriosis typically caused pain symptoms (dysmenorrhea, deep dyspareunia, non-menstrual pelvic pain, and dyschezia) and infertility. Uterine fibroids cause heavy menstrual bleeding, and may affect fertility. These conditions significantly impair quality of life, working efficiency, and sexual life. Although research has improved our knowledge of the genetic and molecular pathways involved in the establishment and progression of these conditions, their pathogenesis remains to be fully understood. Ultrasonography plays a pivotal role in the diagnosis of endometriosis and uterine fibroids; other imaging techniques (such as magnetic resonance imaging, double contrast barium enema) can be used for the diagnosis of endometriosis. Hysteroscopy and sonohysterography may be used to assess the characteristics of uterine fibroids. Hormonal therapies have been widely used for the treatment of symptoms caused by endometriosis and uterine fibroids; however, these therapies are not curative, and symptoms usually recur after the discontinuation of therapies. Alternatively, these conditions can be treated by minimally invasive surgical techniques.

Prof. Simone Ferrero
Guest Editor

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