Recent Advances in Gynecologic Oncology: From Diagnosis to Prognosis

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Medical Imaging and Theranostics".

Deadline for manuscript submissions: closed (31 March 2024) | Viewed by 1415

Special Issue Editor

Special Issue Information

Dear Colleagues,

Cancers of the female genital organs are known explicitly as gynecological cancers, including tubo-ovarian cancer, uterine and cervical cancer, vaginal cancer, and vulvar cancer.

The optimal screening methods for gynecologic cancers are still being investigated. Cervical cancer is the only gynecologic malignancy for which a screening modality is widely accepted and recommended to all women. Surgery is the primary treatment for several gynecological cancer patients. However, further treatment (adjuvant therapy and/or maintenance therapy) is required in some patients. Additionally, in patients with advanced or recurrent diseases, the outcome may be disappointing.

This Special Issue will publish reviews and original papers on detection, prevention, diagnosis, and treatment of gynecologic malignancies. Therefore, gynecologists, medical oncologists, radiation oncologists, radiologists, pathologists, and research scientists with a special interest in gynecological oncology are invited to submit manuscripts for publication in this Special Issue.

Dr. Simone Ferrero
Guest Editor

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Keywords

  • endometriosis
  • ovarian cancer
  • cervical cancer
  • gynecologic endoscopy
  • gynecologic imaging

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Published Papers (1 paper)

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Research

11 pages, 994 KiB  
Article
Radiation-Related Fractures after Radical Radiotherapy for Cervical and Endometrial Cancers: Are There Any Differences?
by Hana Malikova, Katarina Nadova, Klaudia Reginacova, Karin Kremenova and Lukas Rob
Diagnostics 2024, 14(8), 810; https://doi.org/10.3390/diagnostics14080810 - 12 Apr 2024
Viewed by 803
Abstract
In this study, we reviewed CT/MRI scans and studied the rates of radiation-related fractures in subjects treated for cervical cancer (CC, 63 subjects) by radical radiotherapy (RT) and in subjects treated for endometrial cancer (EC, 64 subjects) by radical surgery and RT. The [...] Read more.
In this study, we reviewed CT/MRI scans and studied the rates of radiation-related fractures in subjects treated for cervical cancer (CC, 63 subjects) by radical radiotherapy (RT) and in subjects treated for endometrial cancer (EC, 64 subjects) by radical surgery and RT. The differences between bone density measured in L1 on pretreatment CT, age and body mass index (BMI) were evaluated. Despite significant differences in RT total dose, age, BMI, etc., between both groups, the rate of radiation-related fractures was similar: 28.6% of CC versus 26.6% of EC subjects. CC subjects with fractures were significantly older (62.4 ± 10.1 vs. 49.0 ± 12.4 years; p < 0.001), and their bone densities were significantly lower (106.3 ± 40.0 vs. 168.2 ± 49.5 HU; p < 0.001); no difference in BMI was found. EC subjects with fractures were without significant difference in age but had significantly lower bone densities (103.8 ± 29.0 vs. 133.8 ± 42.3 HU; p = 0.009) and BMIs (26.1 ± 4.9 vs. 31.8 ± 6.9 kg/m2; p = 0.003). Bone density strongly correlated with age (r = −0.755) only in CC subjects. Subjects with fractures from both groups had similarly low bone densities (106.3 ± 40.0 vs. 103.8 ± 29.0 HU; p = 0.829); however, no correlation between bone density and BMI was found. The rate of radiation-related fractures in both groups was clearly associated only with low pretreatment bone density, reflecting osteoporosis. Full article
(This article belongs to the Special Issue Recent Advances in Gynecologic Oncology: From Diagnosis to Prognosis)
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