Special Issue "Chronic Skin Wounds – New Insights in Underlying Pathophysiological Processes, Current Treatment Strategies and Advanced Clinical Approaches"

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Dermatology".

Deadline for manuscript submissions: 31 October 2021.

Special Issue Editor

Dr. Sandra Franz
Guest Editor
Department of Dermatology, Venereology and Allergology, University Leipzig Johannisallee 30, 04103 Leipzig, Germany
Interests: skin inflammation; physiology and pathomechanisms of skin wound healing; immunmodulation; advanced therapeutic concepts for wound healing disorders

Special Issue Information

Chronic wounds are an ulcerative skin defect that fails to proceed through the normal skin repair response. Demographically, the incidence of chronic wounds has reached epidemic levels. On the other hand, current clinical strategies are still limited and often less effective. This highlights the urgent need for new treatment options that require a further understanding of the underlying pathophysiological processes of poor wound healing.

Skin wound healing is a multistage and tightly regulated process. The healthy skin repair response requires spatio-temporal communication between skin-resident cells, invading immune cells and its surrounding extracellular compartment. Failures within this complex communication network results in poor wound healing. Various clinical condition, including vascular diseases and diabetes, compromised immunological status, advanced age or mechanical stress and pressure effects are associated with poor wound healing. However underlying cellular and molecular mechanisms which link these conditions with failures in the various phases of the wound healing response are far from being understood.   

This Special Issue of the Journal of Clinical Medicine on chronic skin wounds is intended to present cutting-edge original research and topical reviews on concepts of chronic wound healing, on existing strategies and on emerging advanced clinical approaches for the prevention and therapy of chronic wounds. Clinical studies on current management strategies of chronic wounds but also dermatoepidemiological studies and lab-based and pre-clinical translational research that increase the knowledge on molecular pathogenesis of chronic wounds and/or may shed light on new therapeutic approaches are welcome.

Dr. Sandra Franz
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Chronic skin wounds
  • CVU
  • DFU
  • Pressure ulcer
  • Chronic wounds and comorbidities
  • Pathomechanisms of chronic wound healing
  • Current management of chronic wounds
  • Immunmodulation
  • Cell-based therapies
  • Combination of therapies
  • Personalizing wound-healing therapies

Published Papers

This special issue is now open for submission.
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