Journal of Clinical Medicine | Most Viewed Papers in 2025
Journal of Clinical Medicine (JCM, ISSN: 2077-0383) is an open access journal that enables researchers to access the latest research findings promptly, promotes transparent academic exchange, and accelerates the dissemination and application of innovative medical research results. Looking back at 2025, many articles published in JCM have drawn more attention and achieved high views. We have selected the top 15 most viewed papers based on their average views. We welcome medical researchers, clinicians, medical students, and medical enthusiasts to read these papers, and hope they can provide valuable new inspiration for relevant research.
1. “An Updated Review of Topical Tretinoin in Dermatology: From Acne and Photoaging to Skin Cancer”
by Pablo Balado-Simó, Daniel Morgado-Carrasco, Sara Gómez-Armayones, Anna López-Ferrer, Didac Barco, Carla Ferrándiz-Pulido and Sebastian Podlipnik
J. Clin. Med. 2025, 14(22), 7958; https://doi.org/10.3390/jcm14227958
Full text available online: https://www.mdpi.com/2077-0383/14/22/7958
2. “Sex Differences in 24 H Blood Pressure in Night-Shift Workers”
by Barbara Toffoli, Silvia Berti, Ilaria Pitteri, Matilde Contessa, Federica Tonon, Rebecca Defendi, Andrea Grillo, Bruno Fabris and Stella Bernardi
J. Clin. Med. 2025, 14(16), 5728; https://doi.org/10.3390/jcm14165728
Full text available online: https://www.mdpi.com/2077-0383/14/16/5728
3. “Artificial Intelligence in Predictive Healthcare: A Systematic Review”
by Abeer Al-Nafjan, Amaal Aljuhani, Arwa Alshebel, Asma Alharbi and Atheer Alshehri
J. Clin. Med. 2025, 14(19), 6752; https://doi.org/10.3390/jcm14196752
Full text available online: https://www.mdpi.com/2077-0383/14/19/6752
4. “The Effectiveness of High-Intensity Interval Training vs. Cardio Training for Weight Loss in Patients with Obesity: A Systematic Review”
by Sławomir Jagsz and Marcin Sikora
J. Clin. Med. 2025, 14(4), 1282; https://doi.org/10.3390/jcm14041282
Full text available online: https://www.mdpi.com/2077-0383/14/4/1282
5. “Understanding Treatment Adherence in Chronic Diseases: Challenges, Consequences, and Strategies for Improvement”
by Sheena Patel, Mingyi Huang and Sophia Miliara
J. Clin. Med. 2025, 14(17), 6034; https://doi.org/10.3390/jcm14176034
Full text available online: https://www.mdpi.com/2077-0383/14/17/6034
6. “Weight Regain After Liraglutide, Semaglutide or Tirzepatide Interruption: A Narrative Review of Randomized Studies”
by Massimo Quarenghi, Silvia Capelli, Giulia Galligani, Arianna Giana, Giorgia Preatoni and Rosamaria Turri Quarenghi
J. Clin. Med. 2025, 14(11), 3791; https://doi.org/10.3390/jcm14113791
Full text available online: https://www.mdpi.com/2077-0383/14/11/3791
7. “Is Targeting LDL-C Levels Below 70 mg/dL Beneficial for Cardiovascular and Overall Health? A Critical Examination of the Evidence”
by Folkert H. van Bruggen and David M. Diamond
J. Clin. Med. 2025, 14(10), 3569; https://doi.org/10.3390/jcm14103569
Full text available online: https://www.mdpi.com/2077-0383/14/10/3569
8. “Postpartum Depression Epidemiology, Risk Factors, Diagnosis, and Management: An Appraisal of the Current Knowledge and Future Perspectives”
by Zaituna Khamidullina, Aizada Marat, Svetlana Muratbekova, Nagima M. Mustapayeva, Gulnar N. Chingayeva, Abay M. Shepetov, Syrdankyz S. Ibatova, Milan Terzic and Gulzhanat Aimagambetova
J. Clin. Med. 2025, 14(7), 2418; https://doi.org/10.3390/jcm14072418
Full text available online: https://www.mdpi.com/2077-0383/14/7/2418
9. “Defining the Chronic Complexities of hEDS and HSD: A Global Survey of Diagnostic Challenges, Life-Long Comorbidities, and Unmet Needs”
by Victoria Daylor, Molly Griggs, Amy Weintraub, Rebecca Byrd, Taylor Petrucci, Matthew Huff, Kathryn Byerly, Roman Fenner, Sydney Severance and Charlotte Griggs et al.
J. Clin. Med. 2025, 14(16), 5636; https://doi.org/10.3390/jcm14165636
Full text available online: https://www.mdpi.com/2077-0383/14/16/5636
10. “Characterization and Management of Adverse Events of Low-Dose Oral Minoxidil Treatment for Alopecia: A Narrative Review”
by Juan Jimenez-Cauhe, Kristen I. Lo Sicco, Jerry Shapiro, Angela Hermosa-Gelbard, Patricia Burgos-Blasco, Ana Melian-Olivera, Daniel Ortega-Quijano, Cristina Pindado-Ortega, Diego Buendia-Castaño, Daniel Asz-Sigall et al.
J. Clin. Med. 2025, 14(6), 1805; https://doi.org/10.3390/jcm14061805
Full text available online: https://www.mdpi.com/2077-0383/14/6/1805
11. “Updated Review of the Management of and Guidelines for Traumatic Brain Injury”
by Aaron Rapp, Hassan Kobeissi and Daniel K. Fahim
J. Clin. Med. 2025, 14(19), 6796; https://doi.org/10.3390/jcm14196796
Full text available online: https://www.mdpi.com/2077-0383/14/19/6796
12. “Review of Recent Treatment Strategies for Lumbar Disc Herniation (LDH) Focusing on Nonsurgical and Regenerative Therapies”
by Jae Sun Lee, Soo-Bin Lee, Kyung-Yil Kang, Seong Ho Oh and Dong-Sik Chae
J. Clin. Med. 2025, 14(4), 1196; https://doi.org/10.3390/jcm14041196
Full text available online: https://www.mdpi.com/2077-0383/14/4/1196
13. “Promising, but Not Completely Conclusive—The Effect of l-Theanine on Cognitive Performance Based on the Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Clinical Trials”
by Rebeka Olga Mátyus, Zsóka Szikora, Diána Bodó, Bettina Vargáné Szabó, Éva Csupor, Dezső Csupor and Barbara Tóth
J. Clin. Med. 2025, 14(21), 7710; https://doi.org/10.3390/jcm14217710
Full text available online: https://www.mdpi.com/2077-0383/14/21/7710
14. “Efficacy of Ergonomic Interventions on Work-Related Musculoskeletal Pain: A Systematic Review and Meta-Analysis”
by Weiner Santos, Carmen Rojas, Rui Isidoro, Alejandro Lorente, Ana Dias, Gonzalo Mariscal, María Benlloch and Rafael Lorente
J. Clin. Med. 2025, 14(9), 3034; https://doi.org/10.3390/jcm14093034
Full text available online: https://www.mdpi.com/2077-0383/14/9/3034
15. “Antiphospholipid Syndrome: A Comprehensive Clinical Review”
by Vasileios Patriarcheas, Georgios Tsamos, Dimitra Vasdeki, Elias Kotteas, Anastasios Kollias, Dimitris Nikas, Georgia Kaiafa and Evangelos Dimakakos
J. Clin. Med. 2025, 14(3), 733; https://doi.org/10.3390/jcm14030733
Full text available online: https://www.mdpi.com/2077-0383/14/3/733