Journal of Clinical Medicine | Highly Cited Papers and Hot Topic Special Issues on Glaucoma

Glaucoma is a group of eye diseases that can cause damage to the optic nerve, leading to visual field defects and even vision loss; its high rate of blindness has become a critical challenge that urgently needs to be addressed in clinical ophthalmology and related medical research. The Journal of Clinical Medicine (JCM, ISSN: 2077-0383) is an international, peer-reviewed, open access journal on clinical and pre-clinical research. We invite you to read the recent highly cited papers on glaucoma and explore related Special Issues focusing on hot topics in glaucoma research.

Furthermore, to discover more hot topics in our “Ophthalmology” Section, please visit here.

1. “Current Status and Future Perspectives of Optic Nerve Imaging in Glaucoma”
by Claudia Lommatzsch and Christian van Oterendorp
J. Clin. Med. 2024, 13(7), 1966; https://doi.org/10.3390/jcm13071966
Full text available online: https://www.mdpi.com/2077-0383/13/7/1966

2. “Optic Nerve Neuroprotection in Glaucoma: A Narrative Review”
by Angela D’Angelo, Livio Vitiello, Filippo Lixi, Giulia Abbinante, Alessia Coppola, Vincenzo Gagliardi, Alfonso Pellegrino and Giuseppe Giannaccare
J. Clin. Med. 2024, 13(8), 2214; https://doi.org/10.3390/jcm13082214
Full text available online: https://www.mdpi.com/2077-0383/13/8/2214

3. “Normal-Tension Glaucoma and Potential Clinical Links to Alzheimer’s Disease”
by Kathleen Ho, Nicole E. Bodi and Tasneem P. Sharma
J. Clin. Med. 2024, 13(7), 1948; https://doi.org/10.3390/jcm13071948
Full text available online: https://www.mdpi.com/2077-0383/13/7/1948

4. “Lights and Shadows on Artificial Intelligence in Glaucoma: Transforming Screening, Monitoring, and Prognosis”
by Alessio Martucci, Gabriele Gallo Afflitto, Giulio Pocobelli, Francesco Aiello, Raffaele Mancino and Carlo Nucci
J. Clin. Med. 2025, 14(7), 2139; https://doi.org/10.3390/jcm14072139
Full text available online: https://www.mdpi.com/2077-0383/14/7/2139

5. “Paul Glaucoma Implant following Congenital Cataract Surgery in a Pediatric Cohort”
by Angi Lizbeth Mendoza-Moreira, Anna Maria Voigt, Julia V. Stingl, Jasmin Rezapour, Felix Mathias Wagner, Alexander K. Schuster and Esther M. Hoffmann
J. Clin. Med. 2024, 13(10), 2914; https://doi.org/10.3390/jcm13102914
Full text available online: https://www.mdpi.com/2077-0383/13/10/2914

6. “Diagnostic Capability of OCTA-Derived Macular Biomarkers for Early to Moderate Primary Open Angle Glaucoma”
by Alice Verticchio Vercellin, Alon Harris, Francesco Oddone, Carmela Carnevale, Brent A. Siesky, Julia Arciero, Brendan Fry, George Eckert, Paul A. Sidoti, Gal Antman et al.
J. Clin. Med. 2024, 13(14), 4190; https://doi.org/10.3390/jcm13144190
Full text available online: https://www.mdpi.com/2077-0383/13/14/4190

7. “Is the Advent of New Surgical Procedures Changing the Baseline Features of Patients Undergoing First-Time Glaucoma Surgery?”
by Alessandro Palma, Giuseppe Covello, Chiara Posarelli, Maria Novella Maglionico, Luca Agnifili and Michele Figus
J. Clin. Med. 2024, 13(11), 3342; https://doi.org/10.3390/jcm13113342
Full text available online: https://www.mdpi.com/2077-0383/13/11/3342

8. ‘Randomized, Cross over, Multicenter, Single-Blind Study Comparing Citicoline 500 mg/Homotaurine 50 mg/Vitamin B3 54 mg/Pyrroloquinoline Quinone 5 mg (Neuprozin Mito^®) and Citicoline 800 mg (Cebrolux^®) on Pattern Electroretinogram (PERG) and Quality of Life in Patients with Primary Open-Angle Glaucoma with Well-Controlled Intraocular Pressure”
by Gemma Caterina Maria Rossi, Michele Rinaldi, Francesco Matarazzo, Diego Strianese, Giuseppe Campagna, Michele La Ragione, Paolo Esposito Veneruso, Giovanni Scapagnini and Ciro Costagliola
J. Clin. Med. 2025, 14(11), 3774; https://doi.org/10.3390/jcm14113774
Full text available online: https://www.mdpi.com/2077-0383/14/11/3774

9. “Clinical Practice Preferences for Glaucoma Surgery in Japan in 2024”
by Kentaro Iwasaki, Shogo Arimura, Yoshihiro Takamura and Masaru Inatani
J. Clin. Med. 2025, 14(6), 2039; https://doi.org/10.3390/jcm14062039
Full text available online: https://www.mdpi.com/2077-0383/14/6/2039

10. “Next-Gen Neuroprotection in Glaucoma: Synergistic Molecules for Targeted Therapy”
by Alessio Martucci, Massimo Cesareo, Maria Dolores Pinazo-Durán, Francesco Aiello, Giulio Pocobelli, Raffaele Mancino and Carlo Nucci
J. Clin. Med. 2025, 14(17), 6145; https://doi.org/10.3390/jcm14176145
Full text available online: https://www.mdpi.com/2077-0383/14/17/6145