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Journal of Cardiovascular Development and Disease publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Clinical Burden of Comorbidities on Cardiovascular System and Beyond: 2nd Edition

edited by

Zbigniew Siudak

submission deadline 31 May 2026 | 5 articles | Viewed by 7266 | Submission Open

Keywords: co-morbidity; inflammation; valves; stents; epidemiology; coronary; diabetes; gender; age; markers

(This special issue belongs to the Section Cardiovascular Clinical Research)

Hybrid Ablation of the Atrial Fibrillation

edited by Massimiliano Marini

submission deadline 31 May 2026 | 3 articles | Viewed by 5484 | Submission Open

Keywords: atrial fibrillation; ablation; hybrid ablation; techniques; videothoracoscopic approach

(This special issue belongs to the Section Electrophysiology and Cardiovascular Physiology)

Role of Biochemical Markers of Cardiovascular Disease in Clinical Practice

edited by Marcello Galvani and Allan S. Jaffe

submission deadline 31 May 2026 | 2 articles | Viewed by 2860 | Submission Open

Keywords: troponin; natriuretic peptides; C-reactive protein; hemostatic markers; inflammatory markers; atherosclerosis; coronary thrombosis

(This special issue belongs to the Section Acquired Cardiovascular Disease)

Transcatheter Aortic Valve Implantation (TAVI): 3rd Edition

edited by

Enrico Ferrari

submission deadline 31 May 2026 | 2 articles | Viewed by 2540 | Submission Open

Keywords: aortic valve; transcatheter aortic valve procedures; transcatheter devices; aortic valve stenosis; paravalvular leak; access sites for TAVI

(This special issue belongs to the Section Cardiac Surgery)

Aortic Surgery—Back to the Roots and Looking to the Future

edited by Ezin Deniz and

Aron-Frederik Popov

submission deadline 31 May 2026 | 3 articles | Viewed by 2212 | Submission Open

Keywords: aortic surgery; hybrid and endovascular innovations; perioperative management; cerebral and organ protection; biomaterials; translational cardiovascular research; imaging in aortic disease; long-term outcomes; cardiovascular surgery

(This special issue belongs to the Section Cardiac Surgery)

Coronary CT Angiography: Emerging and Future Technologies for Precision Cardiovascular Imaging

edited by

David C. Rotzinger

and

Guillaume Fahrni

submission deadline 31 May 2026 | 1 articles | Viewed by 1373 | Submission Open

Keywords: coronary CTA; FFR-CT; AI in imaging; deep learning; artifact reduction; photon-counting CT; cardiovascular diagnostics

(This special issue belongs to the Section Imaging)

Coronary CT Angiography in Percutaneous Coronary Intervention (PCI) Planning: Advances, Applications, and Challenges

edited by Avinainder Singh

submission deadline 31 May 2026 | 1 articles | Viewed by 1236 | Submission Open

Keywords: cardiac CT; PCI planning; YesCCT; coronary artery disease; implementation science

(This special issue belongs to the Section Imaging)

Pathophysiology of Congenital Heart Disease: Emerging Concepts and Mechanisms

edited by

Natasja de Groot

submission deadline 1 Jun 2026 | Viewed by 450 | Submission Open

Keywords: congenital heart disease; pathophysiology; remodeling; mechanisms; personalized care

(This special issue belongs to the Section Pediatric Cardiology and Congenital Heart Disease)

Feature Papers in Imaging—Second Edition

edited by

Nina Ajmone Marsan

and

Tea Gegenava

submission deadline 15 Jun 2026 | 2 articles | Viewed by 1237 | Submission Open

Keywords: echocardiography; cardiac magnetic resonance imaging; cardiac computed tomography; nuclear cardiology; cardiovascular disease

(This special issue belongs to the Section Imaging)

Heart Failure: Clinical Diagnostics and Treatment, 2nd Edition

edited by

Evgeny Belyavskiy

Daniel A. Morris

and

Nicolas Merke

submission deadline 30 Jun 2026 | 7 articles | Viewed by 26756 | Submission Open

Keywords: heart failure; echocardiography; strain imaging; cardiovascular magnetic resonance; heart valve disease; new frontiers in valve therapy intervention and surgery; 3D imaging; lung ultrasound; stress echocardiography; exercise echocardiography in heart valve disease; contrast echocardiography (ultrasound-enhancing agents); echocardiography in mechanical circulatory support (ECMO; Impella; LVAD); atrial fibrillation; ablation; biomarkers; pulmonary vein isolation

(This special issue belongs to the Section Cardiovascular Clinical Research)

Risk Factors and Prevention of Cardiovascular Diseases—Second Edition

edited by Małgorzata Poręba

submission deadline 30 Jun 2026 | 8 articles | Viewed by 12205 | Submission Open

Keywords: cardiovascular diseases; cardiovascular risk factors; smoking; hypertension; hypercholesterolemia; lipids; diabetes; obesity; overweight; diet; occupational factors

(This special issue belongs to the Section Epidemiology, Lifestyle, and Cardiovascular Health)

Cardiovascular Magnetic Resonance in Cardiology Practice: 2nd Edition

edited by

Sebastian Kelle

submission deadline 30 Jun 2026 | 3 articles | Viewed by 9186 | Submission Open

Keywords: cardiovascular magnetic resonance imaging; cardiac MRI; CMR; ischemia; cardiomyopathies; inflammation; vascular; stress testing; education; cardiovascular disease; non-invasive imaging

(This special issue belongs to the Section Imaging)

Heart Valve Surgery: Repair and Replacement

edited by Sameer Hirji and Alexis Kofi Okoh

submission deadline 30 Jun 2026 | 4 articles | Viewed by 8872 | Submission Open

Keywords: aortic stenosis; mitral valve disease; tricuspid regurgitation; mitraclip; transcatheter aortic valve replacement

(This special issue belongs to the Section Cardiac Surgery)

Advancing Cardiac Rehabilitation Delivery and Outcomes: Focusing on Exercise and Lifestyle

edited by

Brett Gordon

and Blake Collins

submission deadline 30 Jun 2026 | 3 articles | Viewed by 4775 | Submission Open

Keywords: secondary prevention; cardiovascular outcomes; digital health; physical activity; models of care

(This special issue belongs to the Section Epidemiology, Lifestyle, and Cardiovascular Health)

Advances in the Prevention and Treatment of Cardiovascular Diseases: What We Addressed and What We Still Need to Address

edited by Alessandro Durante and

Alessandro Mazzapicchi

submission deadline 30 Jun 2026 | 2 articles | Viewed by 3092 | Submission Open

Cutting-Edge Advances in Cardiac Development, Anatomy, and Regeneration

edited by

Diego Franco Jaime

submission deadline 30 Jun 2026 | 3 articles | Viewed by 3058 | Submission Open

Keywords: cardiac structure; congenital heart diseases; cardiovascular progenitors; regulatory mechanisms of cardiac development; cardiovascular epigenetics and differentiation; arrhythmias and the cardiac conduction system; cardiac valves; vascular development; cardiac repair and regeneration; cardiac engineering and organoids

(This special issue belongs to the Section Cardiac Development and Regeneration)

Advances in Cardiac Pacing and Cardiac Resynchronisation Therapy

edited by Chi Keong Ching and Sofian Johar

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1954 | Submission Open

Keywords: pacing in heart failure; His bundle pacing; left bundle branch area pacing; conduction system pacing; cardiac resynchronization therapy; atrioventricular nodal block

(This special issue belongs to the Section Electrophysiology and Cardiovascular Physiology)

Minimally Invasive Coronary Revascularization: State of the Art

edited by Ferdi Akca

submission deadline 30 Jun 2026 | 2 articles | Viewed by 1911 | Submission Open

Keywords: minimally invasive coronary surgery; MICS-CABG; endoscopic mammary artery harvest; MIDCAB; robotic-assisted coronary surgery; endoscopic-assisted coronary bypass surgery (Endo-CAB)

(This special issue belongs to the Section Cardiac Surgery)

Atrial Fibrillation: New Insights and Perspectives

edited by Jean-Baptiste Guichard and

Antoine Da Costa

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1749 | Submission Open

Keywords: atrial fibrillation; electroporation; thermal ablation; pulmonary vein isolation; pulsed field ablation; Marshall alcoholization; clinical trials; dispersion; mapping

(This special issue belongs to the Section Electrophysiology and Cardiovascular Physiology)

Venous Thromboembolism (VTE): Risk, Prevention and Management

edited by

Jorge Moisés

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1374 | Submission Open

Keywords: pulmonary embolism; cardiogenic shock; right ventricle failure; biomarkers; risk stratification; PE treatment; reperfusion; artificial intelligence; bleeding

Advances in Cardiovascular Imaging: An Exciting Future to Revolutionize the Diagnosis and Management of Cardiovascular Disease: 2nd Edition

edited by

Zhonghua Sun

submission deadline 30 Jun 2026 | Viewed by 452 | Submission Open

Keywords: cardiovascular disease; cardiovascular imaging; diagnosis; risk stratification; visualisation; photon counting CT; artificial intelligence; digital twin

Women and Cardiovascular Disease: The Gender Gap—2nd Edition

edited by Sandra Eifert

submission deadline 30 Jun 2026 | Viewed by 309 | Submission Open

Keywords: interventional and surgical treatment of women and cardiovascular disease; heart failure; coronary and valvular heart disease; aortic pathologies; arrhythmias and related basic science; risk factors; hormones

(This special issue belongs to the Section Acquired Cardiovascular Disease)

Hypertrophic Cardiomyopathy: Genetics, Mechanisms and Therapies

edited by Shepard D. Weiner and Lusha W. Liang

submission deadline 4 Jul 2026 | 1 articles | Viewed by 854 | Submission Open

Keywords: obstructive hypertrophic cardiomyopathy; non-obstructive hypertrophic cardiomyopathy; treatment; including cardiac myosin inhibitors; advanced imaging; sudden death risk stratification; atrial fibrillation; heart failure; artificial intelligence; genetics and family screening; exercise considerations

(This special issue belongs to the Section Cardiovascular Clinical Research)

Management and Challenges in Peripheral Arterial Disease

edited by

Christos Rammos

and

Grigorios Korosoglou

submission deadline 15 Jul 2026 | 7 articles | Viewed by 21026 | Submission Open

Keywords: peripheral vascular interventions; endovascular/hybrid/surgical therapy; peripheral perfusion; primary prevention; secondary prevention; peripheral artery disease

(This special issue belongs to the Section Cardiovascular Clinical Research)

Advances in Surgical Treatment of Heart Valve Disease

edited by

Chun Woo Choi

submission deadline 25 Jul 2026 | 1 articles | Viewed by 338 | Submission Open

Keywords: heart valve; structural heart; valvular heart disease; valve repair; valve replacement

(This special issue belongs to the Section Cardiac Surgery)

Contemporary Controversies and Evolving Paradigms in Cardiovascular Surgery

edited by

Dimitrios E. Magouliotis

submission deadline 31 Jul 2026 | 5 articles | Viewed by 9406 | Submission Open

Keywords: cardiovascular surgery; aortic valve replacement (TAVR vs. SAVR); thoracic aortic aneurysms; surgical revascularization; aortic arch disease; ischemic heart failure

(This special issue belongs to the Section Cardiac Surgery)

Acute Myocardial Infarction: Pharmacological and Interventional Treatment

edited by

Antonino Nicosia

and Giuseppe Giacchi

submission deadline 31 Jul 2026 | 5 articles | Viewed by 7283 | Submission Open

Keywords: acute coronary syndromes (ACS); ST-segment elevation myocardial infarction (STEMI); thrombotic coronary lesions; antithrombotic therapy; antiplatelet therapy; thrombus aspiration; mechanical thrombus aspiration; rheolytic thrombectomy

The Present and Future of Sports Cardiology and Exercise, 2nd Edition

edited by

Elena Cavarretta

submission deadline 31 Jul 2026 | 5 articles | Viewed by 4082 | Submission Open

Keywords: sports cardiology; exercise; exercise prescription; electrocardiogram; echocardiography; oxidative stress; cardiomyopathy; heart valve disease; preventive cardiology; cardiac rehabilitation

(This special issue belongs to the Section Epidemiology, Lifestyle, and Cardiovascular Health)

Heart Failure: Focus on Management and Prognosis

edited by

Massimiliano Maines

submission deadline 31 Jul 2026 | 1 articles | Viewed by 2138 | Submission Open

Keywords: heart failure; remote monitoring; telemedicine; device; patient management

(This special issue belongs to the Section Cardiovascular Clinical Research)

Risk Factors and Outcomes in Cardiac Surgery: 2nd Edition

edited by Jae Hwan Choi

submission deadline 31 Jul 2026 | 2 articles | Viewed by 1503 | Submission Open

Keywords: cardiac surgery; outcomes research; risk factor analysis; mechanical circulatory support; heart transplantation

(This special issue belongs to the Section Cardiac Surgery)

Ventricular Arrhythmias: Mechanisms and Management

edited by

Faisal F. Syed

submission deadline 31 Jul 2026 | Viewed by 418 | Submission Open

Keywords: arrhythmia mechanisms; risk prediction; ventricular tachycardia; premature ventricular complex; ventricular fibrillation; catheter ablation; heart failure device therapies; autonomic modulation; GLP-1 agonists; artificial intelligence

(This special issue belongs to the Section Electrophysiology and Cardiovascular Physiology)

Coronary Arterial Anomalies and Coronary Arterial Interventions in Patients with Congenital Heart Disease

edited by

Sameh M. Said

submission deadline 31 Jul 2026 | Viewed by 316 | Submission Open

Keywords: coronary arterial anomalies; coronary arterial interventions; sudden cardiac death; trans-septal course of the left main coronary artery; unroofing; intramural coronary artery; interarterial coronary artery; anomalous aortic origin of the coronary artery

(This special issue belongs to the Section Pediatric Cardiology and Congenital Heart Disease)

Risk Factors in Cardiovascular Health: Focusing on Environmental Contaminants

edited by Ewa Konduracka

submission deadline 30 Aug 2026 | 1 articles | Viewed by 439 | Submission Open

Keywords: cardiovascular complications; environmental contaminants; oxidative stress; endothelial dysfunction; coagulation disturbances

(This special issue belongs to the Section Epidemiology, Lifestyle, and Cardiovascular Health)

Pulmonary Hypertension: Far from a Rare Disease—a Journey from Diagnosis to Treatment

edited by Giovanna Manzi, Silvia Papa and Tommaso Recchioni

submission deadline 31 Aug 2026 | 3 articles | Viewed by 4540 | Submission Open

Keywords: pulmonary hypertension; pathophysiology; diagnosis; treatment; molecular mechanisms; cellular pathways; genetic factors; environmental influences; advanced imaging; biomarkers

(This special issue belongs to the Section Acquired Cardiovascular Disease)

Cardiovascular Disease in Patients with Familial Hypercholesterolemia

edited by Genovefa D. Kolovou, Evangelos Liberopoulos and Haralampos J. Milionis

submission deadline 31 Aug 2026 | 2 articles | Viewed by 4253 | Submission Open

Keywords: familial hypercholesterolemia; atherosclerosis; LDL cholesterol; genetic mutations; lipid-lowering therapies; premature heart disease; risk assessment; early diagnosis; pharmacological treatment

(This special issue belongs to the Section Epidemiology, Lifestyle, and Cardiovascular Health)

Further Understanding of Myocardial Infarction: Risk Factors, Treatment, and Clinical Outcomes

edited by Joanna Sikora

submission deadline 31 Aug 2026 | 3 articles | Viewed by 4041 | Submission Open

Keywords: myocardial infarction; antiplatelet therapy; acute coronary syndromes; cardiovascular risk

(This special issue belongs to the Section Cardiovascular Clinical Research)

Obesity and Heart Failure

edited by

Giuseppe Lisco

submission deadline 31 Aug 2026 | 1 articles | Viewed by 1944 | Submission Open

Keywords: obesity; heart failure with preserved ejection fraction; heart failure with mildly reduced ejection fraction; glucagon-like peptide-1 receptor agonists; sodium– glucose cotransporter-2 inhibitors; resistance exercise

Controversies in Stroke and Cerebrovascular Disease

edited by

Alan P. Sawchuk

submission deadline 31 Aug 2026 | 2 articles | Viewed by 1384 | Submission Open

Keywords: stroke treatment; prevention of large vessel ischemic stroke; anticoagulant therapy for embolic stroke; cryptogenic stroke; neurointerventional management; lytic therapy; blood pressure management

(This special issue belongs to the Section Stroke and Cerebrovascular Disease)

Interventional Diagnostics and Treatment of Coronary Artery Disease

edited by

Tomasz Rakowski

submission deadline 31 Aug 2026 | 1 articles | Viewed by 739 | Submission Open

Keywords: coronary artery disease; myocardial ischemia; myocardial viability; chronic coronary syndromes; acute coronary syndromes; MINOCA; INOCA; coronary revascularization; percutaneous coronary interventions; coronary artery surgical revascularization; coronary artery bypass grafting; cardiac imaging

(This special issue belongs to the Section Acquired Cardiovascular Disease)

Computational Cardiology Models and Methods

edited by

Nicholas G Kounis

and

Cesare De Gregorio

submission deadline 31 Aug 2026 | Viewed by 426 | Submission Open

Keywords: vascular biology; endothelial dysfunction; angiogenesis; inflammation and immune response; heart failure (HFrEF; HFpEF); sudden cardiac death; peripheral artery disease; thrombosis and hemostasis; myocardial infarction; atherosclerosis; hypertension; arrhythmias (AF; VT; VF; etc.); exercise modulation of functional recovery

(This special issue belongs to the Section Basic and Translational Cardiovascular Research)

Advances in Aortic Dissection: Pathophysiology, Diagnosis, and Treatment

edited by Julia Dumfarth and Leonard Pitts

submission deadline 31 Aug 2026 | Viewed by 330 | Submission Open

Keywords: aortic dissection; aortic aneurysm; surgery; hybrid; endovascular; organ protection; malperfusion; hereditary aortic disease

(This special issue belongs to the Section Acquired Cardiovascular Disease)

Recent Advances in Sports Cardiology, 2nd Edition

edited by

David L. Oxborough

submission deadline 31 Aug 2026 | Viewed by 220 | Submission Open

Keywords: athletes’ heart; sport; exercise; screening; echocardiography; electrocardiography; sudden cardiac death

(This special issue belongs to the Section Epidemiology, Lifestyle, and Cardiovascular Health)

Pharmacology Approach Pulmonary Hypertension in Mechanical Ventilated Critical Care Patients

edited by

Antonio Matías Esquìnas

submission deadline 31 Aug 2026 | Viewed by 189 | Submission Open

Keywords: pulmonary hypertension; mechanical ventilation; critical care; pharmacology; weaning mechanical ventilation

(This special issue belongs to the Section Cardiovascular Clinical Research)

Pathophysiology and Treatment of Hypertension: Current Challenges and Future Perspectives

edited by Hua Zhang and De-Pei Li

submission deadline 31 Aug 2026 | Viewed by 188 | Submission Open

Keywords: hypertension; blood pressure regulation; acquired cardiovascular disease; clinical management; pathophysiology; antihypertensive therapy

(This special issue belongs to the Section Acquired Cardiovascular Disease)

Clinical Treatment and Management of Heart Failure

edited by

Jarosław Drożdż

submission deadline 31 Aug 2026 | Viewed by 168 | Submission Open

Keywords: chronic heart failure; acute heart failure; pharmacological treatment; observational studies; routine clinical practice; cardio-oncology; cardiomyopathies

Advances in Arrhythmogenic Cardiomyopathy: Integrating Molecular Insights and Clinical Perspective

edited by

Stephen P. Chelko

and

Andrea Villatore

submission deadline 1 Sep 2026 | Viewed by 373 | Submission Open

Keywords: arrhythmogenic cardiomyopathy; inflammation; genetic/inherited heart disease; immunology; ventricular arrhythmias; heart failure; targeted therapies; sudden cardiac death/arrest; desmosome; environmental/exogenous factors

Omics Technologies in Cardiovascular Disease

edited by

Konstantinos Theofilatos

Anna Zampetaki

Mª Carmen Durán-Ruiz

and Seferina Mavroudi

submission deadline 10 Sep 2026 | Viewed by 157 | Submission Open

Keywords: multi-omics; molecular mechanisms of cardiovascular diseases; mass spectrometry; spatial transcriptomics; single-cell transcriptomics; spatial/single-cell proteomics; biological networks; omics-based CVD Risk scores

(This special issue belongs to the Section Basic and Translational Cardiovascular Research)

Machine Learning and Artificial Intelligence in Cardiovascular Medicine, 2nd Edition

edited by

Chin Siang Ong

submission deadline 25 Sep 2026 | 1 articles | Viewed by 1262 | Submission Open

Keywords: machine learning; artificial intelligence; cardiovascular medicine; cardiovascular disease

(This special issue belongs to the Section Cardiovascular Clinical Research)

Advanced Cardiovascular Imaging in Structural Heart Disease: Diagnostic, Prognostic, and Therapeutic Perspectives

edited by

Alfonso Campanile

, Oliviero Caleo and

Carmine Izzo

submission deadline 30 Sep 2026 | 6 articles | Viewed by 13654 | Submission Open

Keywords: transcatheter aortic valve implantation (TAVI); coronary artery disease (CAD); computed tomography angiography (CTA); cardiovascular disease (CVD); valvular heart disease (VHD); cardiovascular imaging; multimodal imaging; preprocedural imaging

(This special issue belongs to the Section Imaging)