Ventricular Arrhythmias: Mechanisms and Management

A special issue of Journal of Cardiovascular Development and Disease (ISSN 2308-3425). This special issue belongs to the section "Electrophysiology and Cardiovascular Physiology".

Deadline for manuscript submissions: 30 November 2025 | Viewed by 24

Special Issue Editor


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Guest Editor
Division of Cardiology, University of North Carolina, Chapel Hill, NC 27599, USA
Interests: artificial intelligence; machine learning; cardiac electrophysiology; predictive modeling; personalized medicine; signal analysis; big data; supervised learning; unsupervised learning
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Special Issue Information

Dear Colleagues,

Ventricular arrhythmias (VAs) continue to present a formidable challenge, especially among patients with structural heart disease, inherited arrhythmia syndromes, or heart failure. This Special Issue is dedicated to exploring the complex mechanisms behind ventricular tachycardia (VT) and ventricular fibrillation (VF) while showcasing recent advances in both diagnostic tools and therapeutic strategies. Innovations such as pulse field ablation, novel mapping strategies, functional imaging, and the integration of artificial intelligence are reshaping our approach to identifying arrhythmic substrates.

We invite manuscripts that address the full spectrum of emerging therapies in the management of ventricular arrhythmias and heart failure. We welcome studies on state-of-the-art device therapies, including implantable cardioverter-defibrillators (ICDs), subcutaneous ICDs, biventricular pacing, conduction system pacing, cardiac contraction modulation (CCM), and Barostim. We also seek contributions on advanced ablation techniques—from epicardial and complex VT ablation to innovative strategies and targets such as pulse field ablation and radiotherapy—with a particular interest in clinical studies evaluating ablation outcomes in heart failure patients. Additionally, research focusing on premature ventricular contractions (PVCs), autonomic modulation, strategies to prevent heart failure and VT, and interventions designed to improve cardiac function is encouraged. Finally, manuscripts exploring the impact of breakthrough medical therapies, including SGLT2 inhibitors and GLP1 receptor agonists, on arrhythmia management and cardiac performance are highly welcome. With these explosive advances, there has never been a more opportune time to focus on this dynamic and rapidly evolving field.

Dr. Faisal F. Syed
Guest Editor

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Keywords

  • arrhythmia mechanisms
  • risk prediction
  • ventricular tachycardia
  • premature ventricular complex
  • ventricular fibrillation
  • catheter ablation
  • heart failure device therapies
  • autonomic modulation
  • GLP-1 agonists
  • artificial intelligence

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