State of the Art in Mitral Valve Disease

Dear Colleagues,

Mitral valve disease is among the most prevalent valvular disorders, posing a significant challenge due to its high mortality and morbidity rates, especially as the global population ages. Recent advances in research and technology have shed new light on the mechanisms driving the disease, enabling earlier and more precise diagnosis, especially in our understanding of imaging and echocardiography, improved risk stratification, and optimized timing for interventions. Surgery remains the gold standard for treating primary mitral valve disease, and the debate is still going on with standard approaches as opposed to minimally invasive approaches, especially when dealing with long-term results. Percutaneous mitral valve repair and replacement are real noninvasive techniques and have demonstrated promising outcomes. Each treatment needs to be discussed with its pro and cons detailed.

This Special Issue will focus on the latest innovations in mitral valve disease management, from novel imaging modalities for early diagnosis to cutting-edge surgical and micro-invasive therapies. It will also highlight the evolving roles of cardiac anesthesiologists, intensivists, and cardiologists in perioperative care, which are increasingly important in achieving optimal patient outcomes. We invite full research submission "Articles" or comprehensive "Reviews" on these topics, offering a platform for forward-thinking approaches to mitral valve disease.

Prof. Dr. Gilles D. Dreyfus
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Cardiovascular Development and Disease is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• mitral valve pathophysiology and echocardiography
• mitral valve stenosis
• mitral valve regurgitation (primary, secondary, atrial ...)
• standard vs minimally invasive mitral valve surgery
• resection or no resection
• TEER mitral valve “repair” or treatment
• TEER mitral valve replacement: which prosthesis for which patient?
• mitral valve replacement
• mitral valve repair failures: why?
• the future of mitral valve regurgitation