Recent Advances in Fetal Cardiology

A special issue of Journal of Cardiovascular Development and Disease (ISSN 2308-3425). This special issue belongs to the section "Pediatric Cardiology and Congenital Heart Disease".

Deadline for manuscript submissions: 30 September 2025 | Viewed by 341

Special Issue Editor


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Guest Editor
1. Department of Women and Reproductive Medicine, Centro Materno Infantil do Norte Albino Aroso, Centro Hospitalar Universitário de Santo António, 4099-001 Porto, Portugal
2. Institute of Biomedical Sciences Abel Salazar, Universidade do Porto, 4200-319 Porto, Portugal
3. Institute for Research and Innovation in Health, Universidade do Porto, 4200-319 Porto, Portugal
Interests: fetal medicine/prenatal diagnosis; fetal cardiology; fetal pathology; preeclampsia; oxidative stress; fetal Doppler
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Special Issue Information

Dear Colleagues,

As the Guest Editor for an upcoming Special Issue of the Journal of Cardiovascular Development and Disease, I am delighted to extend an invitation to researchers, clinicians, and scientists worldwide to contribute original articles that explore recent advances in fetal cardiology. This Special Issue aims to highlight groundbreaking research, innovative diagnostic techniques, and emerging therapeutic strategies that are shaping the future of fetal cardiac care. Fetal cardiology has seen remarkable progress over the past few decades, and this Special Issue will serve as a platform for disseminating the latest findings and fostering interdisciplinary collaboration in this rapidly evolving field. This Special Issue seeks to cover a wide range of topics related to fetal cardiology. We welcome submissions that address, but are not limited to, the following areas:

Innovations in Prenatal Diagnosis

  • Advances in fetal echocardiography, including 3D and 4D imaging techniques.
  • The role of genetic testing and biomarkers in prenatal screening for CHDs.
  • Integration of artificial intelligence and machine learning in diagnostic processes.

Novel Imaging Modalities

  • The use of fetal magnetic resonance imaging (MRI) in cardiac assessment.
  • Development of new imaging technologies and their clinical applications.
  • Comparative studies of different imaging modalities in fetal cardiology.

In Utero Interventions and Treatments

  • Techniques and outcomes of fetal cardiac interventions, such as balloon valvuloplasty and atrial septostomy.
  • Emerging therapeutic strategies targeting genetic and molecular pathways.
  • Ethical considerations and decision-making processes in fetal interventions.

Postnatal Outcomes and Prognostic Models

  • Long-term outcomes of prenatally diagnosed cardiac conditions.
  • Development and validation of prognostic models to predict postnatal outcomes.
  • Impact of prenatal interventions on postnatal cardiac health.

Interdisciplinary and Collaborative Approaches

  • The role of interdisciplinary teams in managing fetal cardiac conditions.
  • Case studies highlighting collaborative efforts in fetal cardiology.
  • The importance of global collaboration and knowledge sharing in advancing the field.

Prof. Dr. Luís Guedes-Martins
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Cardiovascular Development and Disease is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • prenatal diagnosis
  • fetal cardiology
  • fetal doppler
  • fetal medicine
  • congenital heart disease
  • genetic testing
  • pediatric cardiology

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Published Papers (1 paper)

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Review

20 pages, 6059 KiB  
Review
The Prenatal Diagnosis and Perinatal Management of Congenital Long QT Syndrome: A Comprehensive Literature Review and Recent Updates
by Stefani Samples, Sara Cherny, Nitin Madan, Jeff Hong, Sheena A. Mansukhani, Janette F. Strasburger, Michael R. Carr and Sheetal R. Patel
J. Cardiovasc. Dev. Dis. 2025, 12(4), 156; https://doi.org/10.3390/jcdd12040156 - 14 Apr 2025
Viewed by 318
Abstract
Congenital long QT syndrome (LQTS) is a group of heritable conditions that are associated with cardiac repolarization abnormalities characterized by QT prolongation on electrocardiogram and the risk of life-threatening arrhythmias. The prenatal detection of LQTS presents significant challenges for clinicians, and a multidisciplinary [...] Read more.
Congenital long QT syndrome (LQTS) is a group of heritable conditions that are associated with cardiac repolarization abnormalities characterized by QT prolongation on electrocardiogram and the risk of life-threatening arrhythmias. The prenatal detection of LQTS presents significant challenges for clinicians, and a multidisciplinary approach is required for optimal prenatal and postnatal management. In this comprehensive literature review, we describe strategies for the fetal diagnosis of LQTS with variable initial presentation, genetic testing in suspected fetal LQTS, the utility of fetal magnetocardiography as an additional diagnostic tool, prenatal management, and postnatal treatment. We focus on a multidisciplinary team approach including fetal cardiology, adult and pediatric electrophysiology, neonatology, maternal–fetal medicine, and genetic counselors, all playing vital roles in the comprehensive prenatal management and orchestration of postnatal treatment to optimize neonatal outcomes. Full article
(This article belongs to the Special Issue Recent Advances in Fetal Cardiology)
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