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Journal of Cardiovascular Development and Disease publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Computational Cardiology Models and Methods

edited by

Nicholas G Kounis

and

Cesare De Gregorio

submission deadline 28 Feb 2026 | Viewed by 43 | Submission Open

Keywords: vascular biology; endothelial dysfunction; angiogenesis; inflammation and immune response; heart failure (HFrEF; HFpEF); sudden cardiac death; peripheral artery disease; thrombosis and hemostasis; myocardial infarction; atherosclerosis; hypertension; arrhythmias (AF; VT; VF; etc.); exercise modulation of functional recovery

(This special issue belongs to the Section Basic and Translational Cardiovascular Research)

Atrial Fibrillation: Risk Stratification, Epidemiology, Treatment Advances and Prognostic Interventions

edited by Rui Bebiano Da Providencia E Costa

submission deadline 20 Mar 2026 | 1 articles | Viewed by 294 | Submission Open

Keywords: pulsed field ablation; arrhythmia; pulmonary veins; obesity; multi-morbidity

(This special issue belongs to the Section Electrophysiology and Cardiovascular Physiology)

Contemporary Diagnosis and Management of Hypertensive Heart Disease

edited by

Jonathan Bella

submission deadline 31 Mar 2026 | 1 articles | Viewed by 11938 | Submission Open

Keywords: hypertension; left ventricular hypertrophy; prognosis; genetics; echocardiography; non-invasive cardiac imaging; hypertension treatment; atrial fibrillation; heart failure; coronary artery disease

(This special issue belongs to the Section Acquired Cardiovascular Disease)

Current Status and Future Challenges of Aortic Arch Surgery

edited by

Jason Ali

and Ravi De Silva

submission deadline 31 Mar 2026 | 8 articles | Viewed by 9936 | Submission Open

Keywords: aortic arch; aneurysm; aortic dissection; frozen elephant trunk; TEVAR; acute aortic syndrome; deep hypothermic circulatory arrest; cerebral perfusion; spinal cord protection

(This special issue belongs to the Section Cardiac Surgery)

Heart Valve Surgery: Repair and Replacement

edited by Sameer Hirji and Alexis Kofi Okoh

submission deadline 31 Mar 2026 | 3 articles | Viewed by 4947 | Submission Open

Keywords: aortic stenosis; mitral valve disease; tricuspid regurgitation; mitraclip; transcatheter aortic valve replacement

(This special issue belongs to the Section Cardiac Surgery)

Updates on Atrio-Ventricular Node Anatomy and Physiology and on AVNRTs Circuit

edited by Claudio Pandozi and

Andrea Matteucci

submission deadline 31 Mar 2026 | 2 articles | Viewed by 2393 | Submission Open

Keywords: AV node; Koch's triangle; slow pathway; high‐density mapping

(This special issue belongs to the Section Electrophysiology and Cardiovascular Physiology)

In Vitro Models for Cardiac Development, Regeneration, and Disease: Advances and Challenges

edited by

Richard T. Lee

and

Nivedhitha Velayutham

submission deadline 31 Mar 2026 | 2 articles | Viewed by 2142 | Submission Open

Keywords: in vitro models; stem cell-derived cardiac cells; organ-on-chip platforms; 2D and 3D culture systems; co-culture models; cardiac regeneration; cellular therapies; heart disease modeling

(This special issue belongs to the Section Cardiac Development and Regeneration)

Clinical Outcome and Treatment of Cardiac Arrest

edited by Tsukasa Yagi

submission deadline 31 Mar 2026 | Viewed by 1340 | Submission Open

Keywords: cardiac arrest; post-cardiac arrest syndrome; cardiogenic shock; post-cardiac-arrest care; resuscitation science

(This special issue belongs to the Section Electrophysiology and Cardiovascular Physiology)

Diagnosis and Treatment of Splanchnic and Peripheral Atherosclerotic Disease

edited by Michele Rossi and Marcello Andrea Tipaldi

submission deadline 31 Mar 2026 | 1 articles | Viewed by 1045 | Submission Open

Keywords: photon-counting CT; spectral CT; cardiovascular imaging; visceral aneurysms; critical limb ischemia; visceral atherosclerotic disease; peripheral artery disease; flow-diverting stent; calcified plaque

(This special issue belongs to the Section Acquired Cardiovascular Disease)

Insights into Left Bundle Branch Pacing Mechanics and Efficacy

edited by Francesco Vitali

submission deadline 31 Mar 2026 | 1 articles | Viewed by 845 | Submission Open

Keywords: left bundle branch area pacing; conduction system pacing; ventricular mechanics; myocardial work efficiency; septal pacing; cardiac resynchronization therapy

(This special issue belongs to the Section Electrophysiology and Cardiovascular Physiology)

The Past, Present, and Future of Pulmonary Hypertension: Pathophysiology and Treatment Prospects

edited by Roxana Sulica and Himanshu Deshwal

submission deadline 31 Mar 2026 | Viewed by 84 | Submission Open

Keywords: pulmonary hypertension; exercise-induced pulmonary hypertension; sotatercept; precision-medicine; BMPR2; prostacyclin

(This special issue belongs to the Section Cardiovascular Clinical Research)

Evolving Strategies for the Management of Persistent Atrial Fibrillation

edited by

Riyaz Kaba

submission deadline 31 Mar 2026 | Viewed by 78 | Submission Open

Keywords: atrial fibrillation; persistent atrial fibrillation; heart failure; cardiomyopathies; technology; comorbidities; imaging; mapping; ablation; surgery

(This special issue belongs to the Section Electrophysiology and Cardiovascular Physiology)

Acute Cardiovascular Care in the Cardiological Intensive Care Unit: What Is New?

edited by

Francesca Giordana

and

Andrea Falcetta

submission deadline 31 Mar 2026 | Viewed by 46 | Submission Open

Keywords: cardiological intensive care unit (CICU); cardiogenic shock; acute heart failure; mechanical circulatory support; acute coronary syndromes; pulmonary embolism; non-invasive ventilation; myocarditis; cardiomyopathies

(This special issue belongs to the Section Acquired Cardiovascular Disease)

Emerging Advances in Cardiac Electrophysiology: Mapping, Ablation, and Novel Technologies

edited by

Michael Spartalis

submission deadline 31 Mar 2026 | Viewed by 42 | Submission Open

Keywords: cardiac electrophysiology; atrial fibrillation; ventricular arrhythmias; electroanatomical mapping; catheter ablation; pulsed field ablation (PFA); conduction system pacing; implantable cardiac devices; cardiac imaging and substrate characterization; artificial intelligence in electrophysiology; digital health and remote monitoring; novel technologies and innovations

(This special issue belongs to the Section Electrophysiology and Cardiovascular Physiology)

Artificial Intelligence in Cardiac Surgery and Heart Transplantation

edited by

Stephen Clark

and Jason Moore

submission deadline 1 Apr 2026 | Viewed by 83 | Submission Open

Keywords: artificial intelligence; cardiac surgery; heart transplantation; machine learning; predictive analytics; surgical robotics; assisted medical imaging; clinical decision support

(This special issue belongs to the Section Acquired Cardiovascular Disease)

Arrhythmic Risk Stratification, 2nd Edition

edited by

Marisa Varrenti

and

Patrizio Mazzone

submission deadline 15 Apr 2026 | 1 articles | Viewed by 1309 | Submission Open

Keywords: cardiomyopathies; channelopathies; arrhythmic risk; ventricular arrhythmias; sudden death; genetics; cardiac MRI; ablation of ventricular arrhythmias

(This special issue belongs to the Section Acquired Cardiovascular Disease)

Advances in Diagnosis and Interventional Therapy of Coronary Artery Disease

edited by Dario Buccheri and Stefano Cangemi

submission deadline 15 Apr 2026 | 1 articles | Viewed by 1222 | Submission Open

Keywords: percutaneous coronary intervention (PCI); coronary bifurcation techniques; intracoronary imaging (optical coherence tomography (OCT)); intravascular ultrasound (IVUS); bioresorbable scaffold (BRS); drug-coated balloon (DCB); coronary physiology technique

(This special issue belongs to the Section Acquired Cardiovascular Disease)

Regenerative Medicine in Congenital Heart Disease—Current Status and Future Challenges

edited by Beatrijs Bartelds

submission deadline 15 Apr 2026 | Viewed by 90 | Submission Open

Keywords: congenital heart disease; regenerative medicine; cardiac regeneration; regenerative strategies; iPSC; cardiac tissue engineering; pediatric cardiology

(This special issue belongs to the Section Pediatric Cardiology and Congenital Heart Disease)

Cardiovascular Disease and Nutrition

edited by

Aivars Lejnieks

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1750 | Submission Open

Keywords: dietary patterns; micronutrients; macronutrients; inflammation; oxidative stress; metabolic syndrome; atherosclerosis; hypertension; microbiome

(This special issue belongs to the Section Epidemiology, Lifestyle, and Cardiovascular Health)

Ventricular Arrhythmias: Epidemiology, Diagnosis and Treatment

edited by

Antonio Di Monaco

and

Massimo Grimaldi

submission deadline 30 Apr 2026 | 4 articles | Viewed by 11147 | Submission Open

Keywords: ventricular arrhythmias; electrical storm; Sudden cardiac death; cardiac imaging; catheter ablation; antiarrhythmic drugs; mechanical circulatory support

(This special issue belongs to the Section Cardiovascular Clinical Research)

The Role of Echocardiography in Cardiovascular Diseases

edited by

Daniel A. Morris

submission deadline 30 Apr 2026 | 4 articles | Viewed by 6720 | Submission Open

Keywords: heart failure; valvular heart disease; aortic valve stenosis; mitral valve regurgitation; tricuspid valve regurgitation; aortic valve regurgitation; echocardiography

(This special issue belongs to the Section Imaging)

Congenital Heart Disease: Imaging Diagnosis, Treatment, and Future Challenges

edited by

Jacek Kolcz

submission deadline 30 Apr 2026 | 3 articles | Viewed by 1634 | Submission Open

Keywords: congenital heart disease; 3D echocardiography; cardiac MRI; 3D printing; virtual/augmented reality; catheter-based interventions; surgical results; tissue engineering; regenerative therapies; perioperative management

(This special issue belongs to the Section Pediatric Cardiology and Congenital Heart Disease)

Antithrombotic Therapy in Special and Overlooked Populations with Cardiovascular Diseases

edited by

Leonardo De Luca

submission deadline 30 Apr 2026 | Viewed by 64 | Submission Open

Keywords: antithrombotic therapy; high-risk patients; PCI; bleeding risk; atrial fibrillation; individualized treatment; real-world evidence; complex cardiovascular disease

(This special issue belongs to the Section Cardiovascular Clinical Research)

Advances in Cardiovascular Computed Tomography (CT)

edited by

David C. Rotzinger

submission deadline 30 Apr 2026 | Viewed by 49 | Submission Open

Keywords: computed tomography angiography; cardiovascular imaging; contrast media; spectral computed tomography; quantitative imaging; coronary artery disease; aortic disease; pulmonary embolism; structural heart disease

(This special issue belongs to the Section Imaging)

Risk Assessment and Treatment of Atrial Fibrillation: Focus on Catheter Ablation

edited by Yves De Greef

submission deadline 25 May 2026 | Viewed by 233 | Submission Open

Keywords: atrial fibrillation; catheter ablation; pulmonary vein isolation; advantages; techniques

(This special issue belongs to the Section Electrophysiology and Cardiovascular Physiology)

Role of Biochemical Markers of Cardiovascular Disease in Clinical Practice

edited by Marcello Galvani and Allan S. Jaffe

submission deadline 31 May 2026 | 1 articles | Viewed by 852 | Submission Open

Keywords: troponin; natriuretic peptides; C-reactive protein; hemostatic markers; inflammatory markers; atherosclerosis; coronary thrombosis

(This special issue belongs to the Section Acquired Cardiovascular Disease)

Coronary CT Angiography in Percutaneous Coronary Intervention (PCI) Planning: Advances, Applications, and Challenges

edited by Avinainder Singh

submission deadline 31 May 2026 | Viewed by 151 | Submission Open

Keywords: cardiac CT; PCI planning; YesCCT; coronary artery disease; implementation science

(This special issue belongs to the Section Imaging)

Transcatheter Aortic Valve Implantation (TAVI): 3rd Edition

edited by

Enrico Ferrari

submission deadline 31 May 2026 | 1 articles | Viewed by 147 | Submission Open

Keywords: aortic valve; transcatheter aortic valve procedures; transcatheter devices; aortic valve stenosis; paravalvular leak; access sites for TAVI

(This special issue belongs to the Section Cardiac Surgery)

Multimodal Cardiac Imaging: New and Controversial Insights

edited by

José Ángel Cabrera

and

Javier Urmeneta Ulloa

submission deadline 31 May 2026 | Viewed by 72 | Submission Open

Keywords: cardiac imaging; cardiac magnetic resonance; cardiac computed tomography; multimodal imaging

(This special issue belongs to the Section Imaging)

Coronary CT Angiography: Emerging and Future Technologies for Precision Cardiovascular Imaging

edited by

David C. Rotzinger

and

Guillaume Fahrni

submission deadline 31 May 2026 | Viewed by 61 | Submission Open

Keywords: coronary CTA; FFR-CT; AI in imaging; deep learning; artifact reduction; photon-counting CT; cardiovascular diagnostics

(This special issue belongs to the Section Imaging)

Noninvasive Imaging in Cardiology: From Diagnosis to Treatment

edited by

Ching-Hui Sia

submission deadline 31 May 2026 | Viewed by 21 | Submission Open

Keywords: cardiac imaging; echocardiography; cardiac magnetic resonance; computed tomography; nuclear cardiology; artificial intelligence; risk stratification; diagnosis; therapy guidance; prognosis

(This special issue belongs to the Section Imaging)

Pathophysiology of Congenital Heart Disease: Emerging Concepts and Mechanisms

edited by

Natasja de Groot

submission deadline 1 Jun 2026 | Viewed by 44 | Submission Open

Keywords: congenital heart disease; pathophysiology; remodeling; mechanisms; personalized care

(This special issue belongs to the Section Pediatric Cardiology and Congenital Heart Disease)

Heart Failure: Clinical Diagnostics and Treatment, 2nd Edition

edited by

Evgeny Belyavskiy

Daniel A. Morris

and

Nicolas Merke

submission deadline 30 Jun 2026 | 4 articles | Viewed by 3425 | Submission Open

Keywords: heart failure; echocardiography; strain imaging; cardiovascular magnetic resonance; heart valve disease; new frontiers in valve therapy intervention and surgery; 3D imaging; lung ultrasound; stress echocardiography; exercise echocardiography in heart valve disease; contrast echocardiography (ultrasound-enhancing agents); echocardiography in mechanical circulatory support (ECMO; Impella; LVAD); atrial fibrillation; ablation; biomarkers; pulmonary vein isolation

(This special issue belongs to the Section Cardiovascular Clinical Research)

Advances in the Prevention and Treatment of Cardiovascular Diseases: What We Addressed and What We Still Need to Address

edited by Alessandro Durante and

Alessandro Mazzapicchi

submission deadline 30 Jun 2026 | Viewed by 148 | Submission Open

Advances in Cardiovascular Imaging: An Exciting Future to Revolutionize the Diagnosis and Management of Cardiovascular Disease: 2nd Edition

edited by

Zhonghua Sun

submission deadline 30 Jun 2026 | Viewed by 117 | Submission Open

Keywords: cardiovascular disease; cardiovascular imaging; diagnosis; risk stratification; visualisation; photon counting CT; artificial intelligence; digital twin

Advancing Cardiac Rehabilitation Delivery and Outcomes: Focusing on Exercise and Lifestyle

edited by

Brett Gordon

and Blake Collins

submission deadline 30 Jun 2026 | Viewed by 71 | Submission Open

Keywords: secondary prevention; cardiovascular outcomes; digital health; physical activity; models of care

(This special issue belongs to the Section Epidemiology, Lifestyle, and Cardiovascular Health)

Cutting-Edge Advances in Cardiac Development, Anatomy, and Regeneration

edited by

Diego Franco Jaime

submission deadline 30 Jun 2026 | Viewed by 20 | Submission Open

Keywords: cardiac structure; congenital heart diseases; cardiovascular progenitors; regulatory mechanisms of cardiac development; cardiovascular epigenetics and differentiation; arrhythmias and the cardiac conduction system; cardiac valves; vascular development; cardiac repair and regeneration; cardiac engineering and organoids

(This special issue belongs to the Section Cardiac Development and Regeneration)

Aortic Disease: Pathophysiology, Surgical Management, and Long-Term Outcomes

edited by Daniel Paul Fudulu and Marco Gemelli

submission deadline 30 Sep 2026 | Viewed by 89 | Submission Open

Keywords: aortic pathology; aortic aneurysm; acute aortic syndrome; aortic surgery; endovascular repair; long-term outcomes

(This special issue belongs to the Section Acquired Cardiovascular Disease)

Heart Development Defects: Focus on the Myoarchitecture of the Heart

edited by

Pierre Simon Jouk

submission deadline 31 Jan 2027 | Viewed by 88 | Submission Open

Keywords: heart myoarchitecture; computational anatomy; cardiac imaging; heart development defects

(This special issue belongs to the Section Pediatric Cardiology and Congenital Heart Disease)

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