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Journal of Cardiovascular Development and Disease publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Artificial Intelligence in Cardiac Surgery and Heart Transplantation

edited by

Stephen Clark

and Jason Moore

submission deadline 1 Apr 2026 | Viewed by 147 | Submission Open

Keywords: artificial intelligence; cardiac surgery; heart transplantation; machine learning; predictive analytics; surgical robotics; assisted medical imaging; clinical decision support

(This special issue belongs to the Section Acquired Cardiovascular Disease)

Advances in Diagnosis and Interventional Therapy of Coronary Artery Disease

edited by Dario Buccheri and Stefano Cangemi

submission deadline 15 Apr 2026 | 3 articles | Viewed by 3707 | Submission Open

Keywords: percutaneous coronary intervention (PCI); coronary bifurcation techniques; intracoronary imaging (optical coherence tomography (OCT)); intravascular ultrasound (IVUS); bioresorbable scaffold (BRS); drug-coated balloon (DCB); coronary physiology technique

(This special issue belongs to the Section Acquired Cardiovascular Disease)

Arrhythmic Risk Stratification, 2nd Edition

edited by

Marisa Varrenti

and

Patrizio Mazzone

submission deadline 15 Apr 2026 | 1 articles | Viewed by 1831 | Submission Open

Keywords: cardiomyopathies; channelopathies; arrhythmic risk; ventricular arrhythmias; sudden death; genetics; cardiac MRI; ablation of ventricular arrhythmias

(This special issue belongs to the Section Acquired Cardiovascular Disease)

Regenerative Medicine in Congenital Heart Disease—Current Status and Future Challenges

edited by Beatrijs Bartelds

submission deadline 15 Apr 2026 | Viewed by 123 | Submission Open

Keywords: congenital heart disease; regenerative medicine; cardiac regeneration; regenerative strategies; iPSC; cardiac tissue engineering; pediatric cardiology

(This special issue belongs to the Section Pediatric Cardiology and Congenital Heart Disease)

Cardiovascular Disease and Nutrition

edited by

Aivars Lejnieks

submission deadline 20 Apr 2026 | 4 articles | Viewed by 4702 | Submission Open

Keywords: dietary patterns; micronutrients; macronutrients; inflammation; oxidative stress; metabolic syndrome; atherosclerosis; hypertension; microbiome

(This special issue belongs to the Section Epidemiology, Lifestyle, and Cardiovascular Health)

Ventricular Arrhythmias: Epidemiology, Diagnosis and Treatment

edited by

Antonio Di Monaco

and

Massimo Grimaldi

submission deadline 30 Apr 2026 | 5 articles | Viewed by 12848 | Submission Open

Keywords: ventricular arrhythmias; electrical storm; Sudden cardiac death; cardiac imaging; catheter ablation; antiarrhythmic drugs; mechanical circulatory support

(This special issue belongs to the Section Cardiovascular Clinical Research)

The Role of Echocardiography in Cardiovascular Diseases

edited by

Daniel A. Morris

submission deadline 30 Apr 2026 | 5 articles | Viewed by 9144 | Submission Open

Keywords: heart failure; valvular heart disease; aortic valve stenosis; mitral valve regurgitation; tricuspid valve regurgitation; aortic valve regurgitation; echocardiography

(This special issue belongs to the Section Imaging)

Congenital Heart Disease: Imaging Diagnosis, Treatment, and Future Challenges

edited by

Jacek Kolcz

submission deadline 30 Apr 2026 | 4 articles | Viewed by 3600 | Submission Open

Keywords: congenital heart disease; 3D echocardiography; cardiac MRI; 3D printing; virtual/augmented reality; catheter-based interventions; surgical results; tissue engineering; regenerative therapies; perioperative management

(This special issue belongs to the Section Pediatric Cardiology and Congenital Heart Disease)

Advances in Cardiovascular Computed Tomography (CT)

edited by

David C. Rotzinger

submission deadline 30 Apr 2026 | Viewed by 114 | Submission Open

Keywords: computed tomography angiography; cardiovascular imaging; contrast media; spectral computed tomography; quantitative imaging; coronary artery disease; aortic disease; pulmonary embolism; structural heart disease

(This special issue belongs to the Section Imaging)

Antithrombotic Therapy in Special and Overlooked Populations with Cardiovascular Diseases

edited by

Leonardo De Luca

submission deadline 30 Apr 2026 | Viewed by 93 | Submission Open

Keywords: antithrombotic therapy; high-risk patients; PCI; bleeding risk; atrial fibrillation; individualized treatment; real-world evidence; complex cardiovascular disease

(This special issue belongs to the Section Cardiovascular Clinical Research)

The Future of Cardiac Devices and Electrophysiology

edited by Maciej Sterliński and

Ewa Świerżyńska-Wodarska

submission deadline 30 Apr 2026 | Viewed by 68 | Submission Open

Keywords: cardiac devices; electrophysiology; leadless pacemaker; wearable devices; remote monitoring; telemedicine; arrhythmia detection; electrotherapy; artificial intelligence; digital cardiology

(This special issue belongs to the Section Electrophysiology and Cardiovascular Physiology)

Risk Assessment and Treatment of Atrial Fibrillation: Focus on Catheter Ablation

edited by Yves De Greef

submission deadline 25 May 2026 | 1 articles | Viewed by 1135 | Submission Open

Keywords: atrial fibrillation; catheter ablation; pulmonary vein isolation; advantages; techniques

(This special issue belongs to the Section Electrophysiology and Cardiovascular Physiology)

Coronary Artery Bypasses: Techniques, Outcomes, and Complications

edited by Shahzad G. Raja

submission deadline 30 May 2026 | Viewed by 23 | Submission Open

Keywords: coronary artery bypass grafting; off-pump surgery; arterial revascularization; minimally invasive cardiac surgery; surgical outcomes; perioperative care; long-term survival; graft patency; cardiac surgery complications; clinical trials

(This special issue belongs to the Section Cardiac Surgery)

Clinical Burden of Comorbidities on Cardiovascular System and Beyond: 2nd Edition

edited by

Zbigniew Siudak

submission deadline 31 May 2026 | 4 articles | Viewed by 4012 | Submission Open

Keywords: co-morbidity; inflammation; valves; stents; epidemiology; coronary; diabetes; gender; age; markers

(This special issue belongs to the Section Cardiovascular Clinical Research)

Role of Biochemical Markers of Cardiovascular Disease in Clinical Practice

edited by Marcello Galvani and Allan S. Jaffe

submission deadline 31 May 2026 | 1 articles | Viewed by 1322 | Submission Open

Keywords: troponin; natriuretic peptides; C-reactive protein; hemostatic markers; inflammatory markers; atherosclerosis; coronary thrombosis

(This special issue belongs to the Section Acquired Cardiovascular Disease)

Transcatheter Aortic Valve Implantation (TAVI): 3rd Edition

edited by

Enrico Ferrari

submission deadline 31 May 2026 | 2 articles | Viewed by 1252 | Submission Open

Keywords: aortic valve; transcatheter aortic valve procedures; transcatheter devices; aortic valve stenosis; paravalvular leak; access sites for TAVI

(This special issue belongs to the Section Cardiac Surgery)

Minimal Access Cardiac Surgery: State of the Art and Future Perspectives, 2nd Edition

edited by

Jason M. Ali

submission deadline 31 May 2026 | Viewed by 208 | Submission Open

Keywords: minimal access; minimally invasive; robotic; robot-assisted; cardiac surgery

(This special issue belongs to the Section Cardiac Surgery)

Coronary CT Angiography in Percutaneous Coronary Intervention (PCI) Planning: Advances, Applications, and Challenges

edited by Avinainder Singh

submission deadline 31 May 2026 | Viewed by 180 | Submission Open

Keywords: cardiac CT; PCI planning; YesCCT; coronary artery disease; implementation science

(This special issue belongs to the Section Imaging)

Coronary CT Angiography: Emerging and Future Technologies for Precision Cardiovascular Imaging

edited by

David C. Rotzinger

and

Guillaume Fahrni

submission deadline 31 May 2026 | Viewed by 117 | Submission Open

Keywords: coronary CTA; FFR-CT; AI in imaging; deep learning; artifact reduction; photon-counting CT; cardiovascular diagnostics

(This special issue belongs to the Section Imaging)

Multimodal Cardiac Imaging: New and Controversial Insights

edited by

José Ángel Cabrera

and

Javier Urmeneta Ulloa

submission deadline 31 May 2026 | Viewed by 98 | Submission Open

Keywords: cardiac imaging; cardiac magnetic resonance; cardiac computed tomography; multimodal imaging

(This special issue belongs to the Section Imaging)

Noninvasive Imaging in Cardiology: From Diagnosis to Treatment

edited by

Ching-Hui Sia

submission deadline 31 May 2026 | Viewed by 77 | Submission Open

Keywords: cardiac imaging; echocardiography; cardiac magnetic resonance; computed tomography; nuclear cardiology; artificial intelligence; risk stratification; diagnosis; therapy guidance; prognosis

(This special issue belongs to the Section Imaging)

Pathophysiology of Congenital Heart Disease: Emerging Concepts and Mechanisms

edited by

Natasja de Groot

submission deadline 1 Jun 2026 | Viewed by 174 | Submission Open

Keywords: congenital heart disease; pathophysiology; remodeling; mechanisms; personalized care

(This special issue belongs to the Section Pediatric Cardiology and Congenital Heart Disease)

Heart Failure: Clinical Diagnostics and Treatment, 2nd Edition

edited by

Evgeny Belyavskiy

Daniel A. Morris

and

Nicolas Merke

submission deadline 30 Jun 2026 | 5 articles | Viewed by 10716 | Submission Open

Keywords: heart failure; echocardiography; strain imaging; cardiovascular magnetic resonance; heart valve disease; new frontiers in valve therapy intervention and surgery; 3D imaging; lung ultrasound; stress echocardiography; exercise echocardiography in heart valve disease; contrast echocardiography (ultrasound-enhancing agents); echocardiography in mechanical circulatory support (ECMO; Impella; LVAD); atrial fibrillation; ablation; biomarkers; pulmonary vein isolation

(This special issue belongs to the Section Cardiovascular Clinical Research)

Risk Factors and Prevention of Cardiovascular Diseases—Second Edition

edited by Małgorzata Poręba

submission deadline 30 Jun 2026 | 5 articles | Viewed by 4638 | Submission Open

Keywords: cardiovascular diseases; cardiovascular risk factors; smoking; hypertension; hypercholesterolemia; lipids; diabetes; obesity; overweight; diet; occupational factors

(This special issue belongs to the Section Epidemiology, Lifestyle, and Cardiovascular Health)

Atrial Fibrillation: New Insights and Perspectives

edited by Jean-Baptiste Guichard and

Antoine Da Costa

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1128 | Submission Open

Keywords: atrial fibrillation; electroporation; thermal ablation; pulmonary vein isolation; pulsed field ablation; Marshall alcoholization; clinical trials; dispersion; mapping

(This special issue belongs to the Section Electrophysiology and Cardiovascular Physiology)

Advancing Cardiac Rehabilitation Delivery and Outcomes: Focusing on Exercise and Lifestyle

edited by

Brett Gordon

and Blake Collins

submission deadline 30 Jun 2026 | 1 articles | Viewed by 518 | Submission Open

Keywords: secondary prevention; cardiovascular outcomes; digital health; physical activity; models of care

(This special issue belongs to the Section Epidemiology, Lifestyle, and Cardiovascular Health)

Advances in the Prevention and Treatment of Cardiovascular Diseases: What We Addressed and What We Still Need to Address

edited by Alessandro Durante and

Alessandro Mazzapicchi

submission deadline 30 Jun 2026 | 1 articles | Viewed by 349 | Submission Open

Advances in Cardiovascular Imaging: An Exciting Future to Revolutionize the Diagnosis and Management of Cardiovascular Disease: 2nd Edition

edited by

Zhonghua Sun

submission deadline 30 Jun 2026 | Viewed by 195 | Submission Open

Keywords: cardiovascular disease; cardiovascular imaging; diagnosis; risk stratification; visualisation; photon counting CT; artificial intelligence; digital twin

Cutting-Edge Advances in Cardiac Development, Anatomy, and Regeneration

edited by

Diego Franco Jaime

submission deadline 30 Jun 2026 | Viewed by 189 | Submission Open

Keywords: cardiac structure; congenital heart diseases; cardiovascular progenitors; regulatory mechanisms of cardiac development; cardiovascular epigenetics and differentiation; arrhythmias and the cardiac conduction system; cardiac valves; vascular development; cardiac repair and regeneration; cardiac engineering and organoids

(This special issue belongs to the Section Cardiac Development and Regeneration)

Minimally Invasive Coronary Revascularization: State of the Art

edited by Ferdi Akca

submission deadline 30 Jun 2026 | Viewed by 64 | Submission Open

Keywords: minimally invasive coronary surgery; MICS-CABG; endoscopic mammary artery harvest; MIDCAB; robotic-assisted coronary surgery; endoscopic-assisted coronary bypass surgery (Endo-CAB)

(This special issue belongs to the Section Cardiac Surgery)

Women and Cardiovascular Disease: The Gender Gap—2nd Edition

edited by Sandra Eifert

submission deadline 30 Jun 2026 | Viewed by 51 | Submission Open

Keywords: interventional and surgical treatment of women and cardiovascular disease; heart failure; coronary and valvular heart disease; aortic pathologies; arrhythmias and related basic science; risk factors; hormones

(This special issue belongs to the Section Acquired Cardiovascular Disease)

Management and Challenges in Peripheral Arterial Disease

edited by

Christos Rammos

and

Grigorios Korosoglou

submission deadline 15 Jul 2026 | 6 articles | Viewed by 16957 | Submission Open

Keywords: peripheral vascular interventions; endovascular/hybrid/surgical therapy; peripheral perfusion; primary prevention; secondary prevention; peripheral artery disease

(This special issue belongs to the Section Cardiovascular Clinical Research)

Advances in Surgical Treatment of Heart Valve Disease

edited by

Chun Woo Choi

submission deadline 25 Jul 2026 | Viewed by 32 | Submission Open

Keywords: heart valve; structural heart; valvular heart disease; valve repair; valve replacement

(This special issue belongs to the Section Cardiac Surgery)

Contemporary Controversies and Evolving Paradigms in Cardiovascular Surgery

edited by

Dimitrios E. Magouliotis

submission deadline 31 Jul 2026 | 3 articles | Viewed by 2989 | Submission Open

Keywords: cardiovascular surgery; aortic valve replacement (TAVR vs. SAVR); thoracic aortic aneurysms; surgical revascularization; aortic arch disease; ischemic heart failure

(This special issue belongs to the Section Cardiac Surgery)

Ventricular Arrhythmias: Mechanisms and Management

edited by

Faisal F. Syed

submission deadline 31 Jul 2026 | Viewed by 156 | Submission Open

Keywords: arrhythmia mechanisms; risk prediction; ventricular tachycardia; premature ventricular complex; ventricular fibrillation; catheter ablation; heart failure device therapies; autonomic modulation; GLP-1 agonists; artificial intelligence

(This special issue belongs to the Section Electrophysiology and Cardiovascular Physiology)

Coronary Arterial Anomalies and Coronary Arterial Interventions in Patients with Congenital Heart Disease

edited by

Sameh M. Said

submission deadline 31 Jul 2026 | Viewed by 25 | Submission Open

Keywords: coronary arterial anomalies; coronary arterial interventions; sudden cardiac death; trans-septal course of the left main coronary artery; unroofing; intramural coronary artery; interarterial coronary artery; anomalous aortic origin of the coronary artery

(This special issue belongs to the Section Pediatric Cardiology and Congenital Heart Disease)

Advances in Aortic Dissection: Pathophysiology, Diagnosis, and Treatment

edited by Julia Dumfarth and Leonard Pitts

submission deadline 31 Aug 2026 | Viewed by 96 | Submission Open

Keywords: aortic dissection; aortic aneurysm; surgery; hybrid; endovascular; organ protection; malperfusion; hereditary aortic disease

(This special issue belongs to the Section Acquired Cardiovascular Disease)

Advances in Arrhythmogenic Cardiomyopathy: Integrating Molecular Insights and Clinical Perspective

edited by

Stephen P. Chelko

and

Andrea Villatore

submission deadline 1 Sep 2026 | Viewed by 79 | Submission Open

Keywords: arrhythmogenic cardiomyopathy; inflammation; genetic/inherited heart disease; immunology; ventricular arrhythmias; heart failure; targeted therapies; sudden cardiac death/arrest; desmosome; environmental/exogenous factors

Aortic Disease: Pathophysiology, Surgical Management, and Long-Term Outcomes

edited by Daniel Paul Fudulu and Marco Gemelli

submission deadline 30 Sep 2026 | Viewed by 183 | Submission Open

Keywords: aortic pathology; aortic aneurysm; acute aortic syndrome; aortic surgery; endovascular repair; long-term outcomes

(This special issue belongs to the Section Acquired Cardiovascular Disease)

Optimizing Thrombosis Management in Contemporary Interventional Cardiology After Transradial Coronary Catheterization

edited by

Matthaios V. Didagelos

submission deadline 30 Sep 2026 | Viewed by 13 | Submission Open

Keywords: thrombosis in interventional cardiology; transradial coronary catheterization; percutaneous coronary intervention (PCI); acute coronary syndromes (ACS); bleeding risk mitigation; vascular complications; radial artery occlusion

(This special issue belongs to the Section Cardiovascular Clinical Research)

Acute Pulmonary Embolism: A Cardiovascular Emergency

edited by Claudio Picariello and Marco Zuin

submission deadline 31 Dec 2026 | Viewed by 18 | Submission Open

Keywords: thrombolysis ; catheter directed therapies ; direct oral anticoagulants ; risk stratification ; pulmonary embolism response team ; long-term anticoagulation

(This special issue belongs to the Section Acquired Cardiovascular Disease)

Heart Development Defects: Focus on the Myoarchitecture of the Heart

edited by

Pierre Simon Jouk

submission deadline 31 Jan 2027 | Viewed by 110 | Submission Open

Keywords: heart myoarchitecture; computational anatomy; cardiac imaging; heart development defects

(This special issue belongs to the Section Pediatric Cardiology and Congenital Heart Disease)

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