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Journal of Cardiovascular Development and Disease publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Contemporary Controversies and Evolving Paradigms in Cardiovascular Surgery

edited by

Dimitrios E. Magouliotis

submission deadline 31 Dec 2025 | Viewed by 88 | Submission Open

Keywords: cardiovascular surgery; aortic valve replacement (TAVR vs. SAVR); thoracic aortic aneurysms; surgical revascularization; aortic arch disease; ischemic heart failure

(This special issue belongs to the Section Cardiac Surgery)

Feature Papers in Imaging—Second Edition

edited by

Nina Ajmone Marsan

and

Tea Gegenava

submission deadline 31 Dec 2025 | Viewed by 82 | Submission Open

Keywords: echocardiography; cardiac magnetic resonance imaging; cardiac computed tomography; nuclear cardiology; cardiovascular disease

(This special issue belongs to the Section Imaging)

Venous Thromboembolism (VTE): Risk, Prevention and Management

edited by

Jorge Moisés

submission deadline 31 Dec 2025 | Viewed by 79 | Submission Open

Keywords: pulmonary embolism; cardiogenic shock; right ventricle failure; biomarkers; risk stratification; PE treatment; reperfusion; artificial intelligence; bleeding

Emerging Trends and Advances in Interventional Cardiology

edited by Vlasis Ninios and

Georgios Papadopoulos

submission deadline 31 Jan 2026 | 2 articles | Viewed by 1729 | Submission Open

Keywords: interventional cardiology; coronary artery disease; structural heart disease; percutaneous coronary intervention; aortic stenosis; mitral regurgitation; tricuspid regurgitation

(This special issue belongs to the Section Cardiovascular Clinical Research)

Acute Myocardial Infarction: Pharmacological and Interventional Treatment

edited by

Antonino Nicosia

and Giuseppe Giacchi

submission deadline 31 Jan 2026 | 2 articles | Viewed by 1447 | Submission Open

Keywords: acute coronary syndromes (ACS); ST-segment elevation myocardial infarction (STEMI); thrombotic coronary lesions; antithrombotic therapy; antiplatelet therapy; thrombus aspiration; mechanical thrombus aspiration; rheolytic thrombectomy

Stroke in the Young

edited by

Narayanaswamy Venketasubramanian

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1079 | Submission Open

Keywords: young; neonate; child; cerebrovascular disease; stroke; cerebral infarction; intracerebral haemorrhage; subarachnoid haemorrhage; risk factors; mechanisms; prognosis; outcomes; complications

(This special issue belongs to the Section Stroke and Cerebrovascular Disease)

Advances in Cardiac Pacing and Cardiac Resynchronisation Therapy

edited by Chi Keong Ching

submission deadline 31 Jan 2026 | 1 articles | Viewed by 694 | Submission Open

Keywords: pacing in heart failure; His bundle pacing; left bundle branch area pacing; conduction system pacing; cardiac resynchronization therapy; atrioventricular nodal block

(This special issue belongs to the Section Electrophysiology and Cardiovascular Physiology)

The Present and Future of Sports Cardiology and Exercise, 2nd Edition

edited by

Elena Cavarretta

submission deadline 31 Jan 2026 | Viewed by 89 | Submission Open

Keywords: sports cardiology; exercise; exercise prescription; electrocardiogram; echocardiography; oxidative stress; cardiomyopathy; heart valve disease; preventive cardiology; cardiac rehabilitation

(This special issue belongs to the Section Epidemiology, Lifestyle, and Cardiovascular Health)

Recent Advances in Transcatheter Closure of Atrial Septal Defects (ASD) and Ventricular Septal Defects (VSD)

edited by Mario Carminati, Israel Valverde and Xiangbin Pan

submission deadline 31 Jan 2026 | Viewed by 78 | Submission Open

Keywords: ASD; VSD; multiple septal defects; transcatheter closure; reabsorbable devices

(This special issue belongs to the Section Pediatric Cardiology and Congenital Heart Disease)

Advanced Cardiovascular Imaging in Structural Heart Disease: Diagnostic, Prognostic, and Therapeutic Perspectives

edited by

Alfonso Campanile

, Oliviero Caleo and

Carmine Izzo

submission deadline 31 Jan 2026 | Viewed by 77 | Submission Open

Keywords: transcatheter aortic valve implantation (TAVI); coronary artery disease (CAD); computed tomography angiography (CTA); cardiovascular disease (CVD); valvular heart disease (VHD); cardiovascular imaging; multimodal imaging; preprocedural imaging

(This special issue belongs to the Section Imaging)

Feature Review Papers in the ‘Genetics’ Section

edited by

Maria Grazia Andreassi

submission deadline 31 Jan 2026 | Viewed by 53 | Submission Open

Keywords: genetics; genomics; polygenic risk scores; genome-wide association studies (GWAS); rare variants; pharmacogenomics; exposome; gene– environment interactions; multi-omics

(This special issue belongs to the Section Genetics)

Risk Factors and Outcomes in Cardiac Surgery: 2nd Edition

edited by Jae Hwan Choi

submission deadline 31 Jan 2026 | Viewed by 51 | Submission Open

Keywords: cardiac surgery; outcomes research; risk factor analysis; mechanical circulatory support; heart transplantation

(This special issue belongs to the Section Cardiac Surgery)

Controversies in Stroke and Cerebrovascular Disease

edited by

Alan P. Sawchuk

submission deadline 31 Jan 2026 | Viewed by 29 | Submission Open

Keywords: stroke treatment; prevention of large vessel ischemic stroke; anticoagulant therapy for embolic stroke; cryptogenic stroke; neurointerventional management; lytic therapy; blood pressure management

Advanced Cardiovascular Imaging in Cardiomyopathy

edited by

Luca Arcari

submission deadline 31 Jan 2026 | Viewed by 13 | Submission Open

Keywords: cardiomyopathies; hypertrophic cardiomyopathy; dilated cardiomyopathy; cardiac amyloidosis; arrhythmogenic right ventricular cardiomyopathy; non-dilated left ventricular cardiomyopathy; cardiac magnetic resonance imaging; computed tomography; echocardiography; nuclear imaging

Feature Review Papers in Cardiovascular Clinical Research

edited by

Jochen Wöhrle

submission deadline 28 Feb 2026 | 6 articles | Viewed by 6220 | Submission Open

Keywords: cardiovascular disease; interventional therapy; drugs; medication; prognosis; rehabilitation; acute cardiovascular care; Intensive cardiovascular care

(This special issue belongs to the Section Cardiovascular Clinical Research)

Cardiovascular Disease in Patients with Familial Hypercholesterolemia

edited by Genovefa D. Kolovou, Evangelos Liberopoulos and Haralampos J. Milionis

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1763 | Submission Open

Keywords: familial hypercholesterolemia; atherosclerosis; LDL cholesterol; genetic mutations; lipid-lowering therapies; premature heart disease; risk assessment; early diagnosis; pharmacological treatment

(This special issue belongs to the Section Epidemiology, Lifestyle, and Cardiovascular Health)

Advances in Thrombosis Diagnosis and Antithrombotic Therapy

edited by Ovidio De Filippo,

Fabrizio D’Ascenzo

and Francesco Antonio Veneziano

submission deadline 28 Feb 2026 | Viewed by 32 | Submission Open

Keywords: antithrombotic therapy; ischemic heart disease; risk stratification; personalized medicine; dual antiplatelet therapy; bleeding risk; coronary artery disease; artificial intelligence

Critical Care Update: Cardiology

edited by

Sasa Rajsic

and

Benedikt Treml

submission deadline 28 Feb 2026 | Viewed by 23 | Submission Open

Keywords: critical care; cardiology; resuscitation; PCA; myocardial infarct; acute illness; intensive care; shock; cardiogenic shock; ECMO; arrhythmias; STEMI

(This special issue belongs to the Section Cardiovascular Clinical Research)

Pulmonary Hypertension: Far from a Rare Disease—a Journey from Diagnosis to Treatment

edited by Giovanna Manzi, Silvia Papa and Tommaso Recchioni

submission deadline 28 Feb 2026 | Viewed by 22 | Submission Open

Keywords: pulmonary hypertension; pathophysiology; diagnosis; treatment; molecular mechanisms; cellular pathways; genetic factors; environmental influences; advanced imaging; biomarkers

(This special issue belongs to the Section Acquired Cardiovascular Disease)

Heart Failure: Advanced Imaging and New Treatments

edited by

Antonello D’Andrea

Alfredo Mauriello

and Adriana Correra

submission deadline 28 Feb 2026 | Viewed by 21 | Submission Open

Keywords: heart failure; biomarkers; cardiomyopathies; device therapy; echocardiography; imaging; arrythmias; cardiac rehabilitation; heart valve disease

Atrial Fibrillation: Current Considerations for Diagnosis, Therapy, and Management

edited by

Giulio Molon

and Stefano Bonapace

submission deadline 28 Feb 2026 | Viewed by 18 | Submission Open

Keywords: rhythm control; anticoagulation; catheter ablation; pulsed-field ablation; cryoablation; paroxysmal AF; persistent AF; left atrial appendage (LAA); antiarrhythmic drug

(This special issue belongs to the Section Electrophysiology and Cardiovascular Physiology)

Updates on Atrio-Ventricular Node Anatomy and Physiology and on AVNRTs Circuit

edited by Claudio Pandozi and

Andrea Matteucci

submission deadline 31 Mar 2026 | 1 articles | Viewed by 353 | Submission Open

Keywords: AV node; Koch's triangle; slow pathway; high‐density mapping

(This special issue belongs to the Section Electrophysiology and Cardiovascular Physiology)

Insights into Left Bundle Branch Pacing Mechanics and Efficacy

edited by Francesco Vitali

submission deadline 31 Mar 2026 | Viewed by 14 | Submission Open

Keywords: left bundle branch area pacing; conduction system pacing; ventricular mechanics; myocardial work efficiency; septal pacing; cardiac resynchronization therapy

(This special issue belongs to the Section Electrophysiology and Cardiovascular Physiology)

Artificial Intelligence in Cardiac Surgery and Heart Transplantation

edited by

Stephen Clark

and Jason Moore

submission deadline 1 Apr 2026 | Viewed by 19 | Submission Open

Keywords: artificial intelligence; cardiac surgery; heart transplantation; machine learning; predictive analytics; surgical robotics; assisted medical imaging; clinical decision support

(This special issue belongs to the Section Acquired Cardiovascular Disease)

Ventricular Arrhythmias: Epidemiology, Diagnosis and Treatment

edited by

Antonio Di Monaco

and

Massimo Grimaldi

submission deadline 30 Apr 2026 | 4 articles | Viewed by 9711 | Submission Open

Keywords: ventricular arrhythmias; electrical storm; Sudden cardiac death; cardiac imaging; catheter ablation; antiarrhythmic drugs; mechanical circulatory support

(This special issue belongs to the Section Cardiovascular Clinical Research)

The Role of Echocardiography in Cardiovascular Diseases

edited by

Daniel A. Morris

submission deadline 30 Apr 2026 | 3 articles | Viewed by 4420 | Submission Open

Keywords: heart failure; valvular heart disease; aortic valve stenosis; mitral valve regurgitation; tricuspid valve regurgitation; aortic valve regurgitation; echocardiography

(This special issue belongs to the Section Imaging)

Multimodal Cardiac Imaging: New and Controversial Insights

edited by

José Ángel Cabrera

and