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Journal of Cardiovascular Development and Disease publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Machine Learning and Artificial Intelligence in Cardiovascular Medicine, 2nd Edition

edited by

Chin Siang Ong

submission deadline 25 Sep 2026 | 1 articles | Viewed by 1218 | Submission Open

Keywords: machine learning; artificial intelligence; cardiovascular medicine; cardiovascular disease

(This special issue belongs to the Section Cardiovascular Clinical Research)

Advanced Cardiovascular Imaging in Structural Heart Disease: Diagnostic, Prognostic, and Therapeutic Perspectives

edited by

Alfonso Campanile

, Oliviero Caleo and

Carmine Izzo

submission deadline 30 Sep 2026 | 6 articles | Viewed by 13482 | Submission Open

Keywords: transcatheter aortic valve implantation (TAVI); coronary artery disease (CAD); computed tomography angiography (CTA); cardiovascular disease (CVD); valvular heart disease (VHD); cardiovascular imaging; multimodal imaging; preprocedural imaging

(This special issue belongs to the Section Imaging)

Aortic Disease: Pathophysiology, Surgical Management, and Long-Term Outcomes

edited by Daniel Paul Fudulu and

Marco Gemelli

submission deadline 30 Sep 2026 | 4 articles | Viewed by 3396 | Submission Open

Keywords: aortic pathology; aortic aneurysm; acute aortic syndrome; aortic surgery; endovascular repair; long-term outcomes

(This special issue belongs to the Section Acquired Cardiovascular Disease)

Critical Care Update: Cardiology

edited by

Sasa Rajsic

and

Benedikt Treml

submission deadline 30 Sep 2026 | 1 articles | Viewed by 2968 | Submission Open

Keywords: critical care; cardiology; resuscitation; PCA; myocardial infarct; acute illness; intensive care; shock; cardiogenic shock; ECMO; arrhythmias; STEMI

(This special issue belongs to the Section Cardiovascular Clinical Research)

Heart Failure: Advanced Imaging and New Treatments

edited by

Antonello D’Andrea

Alfredo Mauriello

and Adriana Correra

submission deadline 30 Sep 2026 | 1 articles | Viewed by 2806 | Submission Open

Keywords: heart failure; biomarkers; cardiomyopathies; device therapy; echocardiography; imaging; arrythmias; cardiac rehabilitation; heart valve disease

Recent Advances in Transcatheter Closure of Atrial Septal Defects (ASD) and Ventricular Septal Defects (VSD)

edited by Mario Carminati, Israel Valverde and Xiangbin Pan

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1459 | Submission Open

Keywords: ASD; VSD; multiple septal defects; transcatheter closure; reabsorbable devices

(This special issue belongs to the Section Pediatric Cardiology and Congenital Heart Disease)

Transcatheter and Surgical Approaches to Complications of Transcatheter Procedures: Current Trends and Future Challenges, 2nd Edition

edited by

Antonio Nenna

Giuseppe Patti

and Giovanni Casali

submission deadline 30 Sep 2026 | 1 articles | Viewed by 869 | Submission Open

Keywords: transcatheter; complications; cardiac surgery; heart valve surgery; complications; TAVR

(This special issue belongs to the Section Cardiac Surgery)

Atrial Fibrillation: Current Considerations for Diagnosis, Therapy, and Management

edited by

Giulio Molon

and Stefano Bonapace

submission deadline 30 Sep 2026 | 1 articles | Viewed by 768 | Submission Open

Keywords: rhythm control; anticoagulation; catheter ablation; pulsed-field ablation; cryoablation; paroxysmal AF; persistent AF; left atrial appendage (LAA); antiarrhythmic drug

(This special issue belongs to the Section Electrophysiology and Cardiovascular Physiology)

Advanced Cardiovascular Imaging in Cardiomyopathy

edited by

Luca Arcari

submission deadline 30 Sep 2026 | Viewed by 409 | Submission Open

Keywords: cardiomyopathies; hypertrophic cardiomyopathy; dilated cardiomyopathy; cardiac amyloidosis; arrhythmogenic right ventricular cardiomyopathy; non-dilated left ventricular cardiomyopathy; cardiac magnetic resonance imaging; computed tomography; echocardiography; nuclear imaging

The Role of Extracorporeal Membrane Oxygenation (ECMO) in Cardiovascular Disease

edited by Ahmet Rüçhan Akar and Mehmet Cahit Sarıcaoğlu

submission deadline 30 Sep 2026 | Viewed by 244 | Submission Open

Keywords: extracorporeal membrane oxygenation (ECMO); VA-ECMO; ECPR; cardiogenic shock; mechanical circulatory support (MCS); heart transplantation; ventricular assist devices (VAD); left ventricular unloading; anticoagulation and hemocompatibility; critical care cardiology/cardiac intensive care

(This special issue belongs to the Section Acquired Cardiovascular Disease)

Optimizing Thrombosis Management in Contemporary Interventional Cardiology After Transradial Coronary Catheterization

edited by

Matthaios V. Didagelos

submission deadline 30 Sep 2026 | Viewed by 187 | Submission Open

Keywords: thrombosis in interventional cardiology; transradial coronary catheterization; percutaneous coronary intervention (PCI); acute coronary syndromes (ACS); bleeding risk mitigation; vascular complications; radial artery occlusion

(This special issue belongs to the Section Cardiovascular Clinical Research)

Comprehensive Insights into Ischemic Stroke: Risk Factors, Mechanisms, Clinical Care, and Patient Recovery

edited by

Narayanaswamy Venketasubramanian

submission deadline 30 Sep 2026 | Viewed by 138 | Submission Open

Keywords: ischaemic stroke; cerebrovascular disease; risk factors; mechanisms; clinical care; recovery; outcomes

(This special issue belongs to the Section Stroke and Cerebrovascular Disease)

Plasma Biomarkers for the Diagnosis and Prognosis of Cardiac Ischemic Events or Contractile Dysfunction

edited by

Óscar Lorenzo González

submission deadline 30 Sep 2026 | Viewed by 133 | Submission Open

Keywords: cardiac biomarkers; myocardial ischemia; contractile dysfunction; prognostic indicators

(This special issue belongs to the Section Basic and Translational Cardiovascular Research)

Congenital Heart Disease: Technological Innovations in Cardiac Surgery and Interventional Therapy

edited by Martin Schweiger

submission deadline 20 Oct 2026 | 8 articles | Viewed by 15155 | Submission Open

Keywords: minimal invasive procedures in pediatric cardiac surgery; 3D printing; advanced imaging modalities; bioresorbable devices; artificial intelligence; tissue engineering; growth

(This special issue belongs to the Section Pediatric Cardiology and Congenital Heart Disease)

The Future of Cardiac Devices and Electrophysiology

edited by Maciej Sterliński and

Ewa Świerżyńska-Wodarska

submission deadline 30 Oct 2026 | Viewed by 255 | Submission Open

Keywords: cardiac devices; electrophysiology; leadless pacemaker; wearable devices; remote monitoring; telemedicine; arrhythmia detection; electrotherapy; artificial intelligence; digital cardiology

(This special issue belongs to the Section Electrophysiology and Cardiovascular Physiology)

Acute Cardiovascular Care in the Cardiological Intensive Care Unit: What Is New?

edited by

Francesca Giordana

and

Andrea Falcetta

submission deadline 31 Oct 2026 | 3 articles | Viewed by 7318 | Submission Open

Keywords: cardiological intensive care unit (CICU); cardiogenic shock; acute heart failure; mechanical circulatory support; acute coronary syndromes; pulmonary embolism; non-invasive ventilation; myocarditis; cardiomyopathies

(This special issue belongs to the Section Acquired Cardiovascular Disease)

Atrial Fibrillation: Risk Stratification, Epidemiology, Treatment Advances and Prognostic Interventions

edited by Rui Bebiano Da Providencia E Costa

submission deadline 31 Oct 2026 | 3 articles | Viewed by 2538 | Submission Open

Keywords: pulsed field ablation; arrhythmia; pulmonary veins; obesity; multi-morbidity

(This special issue belongs to the Section Electrophysiology and Cardiovascular Physiology)

Artificial Intelligence in Cardiac Surgery and Heart Transplantation

edited by

Stephen Clark

and Jason Moore

submission deadline 31 Oct 2026 | 1 articles | Viewed by 1036 | Submission Open

Keywords: artificial intelligence; cardiac surgery; heart transplantation; machine learning; predictive analytics; surgical robotics; assisted medical imaging; clinical decision support

(This special issue belongs to the Section Acquired Cardiovascular Disease)

Multidisciplinary Decision-Making and Patient Selection in Complex Structural Heart Interventions

edited by Vlasis Ninios and

Georgios Papadopoulos

submission deadline 31 Oct 2026 | 1 articles | Viewed by 580 | Submission Open

Keywords: structural heart disease; multidisciplinary heart team; complex valvular heart disease; transcatheter valve interventions; transcatheter edge-to-edge repair; transcatheter valve replacement; adult congenital heart disease; TAVI; TMVR; TTVR

(This special issue belongs to the Section Cardiovascular Clinical Research)

Advanced Echocardiographic Imaging Using Speckle-Tracking for Assessment of Cardiac Mechanics

edited by Christos G. Mihos

submission deadline 31 Oct 2026 | Viewed by 224 | Submission Open

Keywords: cardiac imaging; cardiac mechanics; cardiomyopathy; cardio-oncology; global longitudinal strain; speckle-tracking echocardiography; strain echocardiography

(This special issue belongs to the Section Imaging)

Echocardiography in Cardio-Oncology: From Early Detection to Established Cardiovascular Disease

edited by Matthias Schneider-Reigbert

submission deadline 31 Oct 2026 | Viewed by 146 | Submission Open

Keywords: cardio-oncology; echocardiography; cancer therapy-related cardiotoxicity; non-bacterial thrombotic endocarditis; pericardial disease; intracardiac masses

(This special issue belongs to the Section Imaging)

Advancements in the Management of Aortic Stenosis: The Importance of Early Detection and Timely Treatment

edited by

Antonio Micari

and Giulia Laterra

submission deadline 25 Nov 2026 | Viewed by 143 | Submission Open

Keywords: aortic stenosis; transcatheter aortic valve replacement; early intervention; risk stratification; bicuspid aortic valve; cardiac imaging

(This special issue belongs to the Section Cardiovascular Clinical Research)

Feature Review Papers in the ‘Genetics’ Section

edited by

Maria Grazia Andreassi

submission deadline 30 Nov 2026 | 2 articles | Viewed by 5584 | Submission Open

Keywords: genetics; genomics; polygenic risk scores; genome-wide association studies (GWAS); rare variants; pharmacogenomics; exposome; gene– environment interactions; multi-omics

(This special issue belongs to the Section Genetics)

The Past, Present, and Future of Pulmonary Hypertension: Pathophysiology and Treatment Prospects

edited by Roxana Sulica and Himanshu Deshwal

submission deadline 30 Nov 2026 | 1 articles | Viewed by 2122 | Submission Open

Keywords: pulmonary hypertension; exercise-induced pulmonary hypertension; sotatercept; precision-medicine; BMPR2; prostacyclin

(This special issue belongs to the Section Cardiovascular Clinical Research)

Advances in Thrombosis Diagnosis and Antithrombotic Therapy

edited by Ovidio De Filippo,

Fabrizio D’Ascenzo

and Francesco Antonio Veneziano

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1282 | Submission Open

Keywords: antithrombotic therapy; ischemic heart disease; risk stratification; personalized medicine; dual antiplatelet therapy; bleeding risk; coronary artery disease; artificial intelligence

Advances in Cardiovascular Computed Tomography (CT)

edited by

David C. Rotzinger

submission deadline 30 Nov 2026 | 2 articles | Viewed by 1008 | Submission Open

Keywords: computed tomography angiography; cardiovascular imaging; contrast media; spectral computed tomography; quantitative imaging; coronary artery disease; aortic disease; pulmonary embolism; structural heart disease

(This special issue belongs to the Section Imaging)

Regenerative Medicine in Congenital Heart Disease—Current Status and Future Challenges

edited by Beatrijs Bartelds

submission deadline 30 Nov 2026 | Viewed by 314 | Submission Open

Keywords: congenital heart disease; regenerative medicine; cardiac regeneration; regenerative strategies; iPSC; cardiac tissue engineering; pediatric cardiology

(This special issue belongs to the Section Pediatric Cardiology and Congenital Heart Disease)

Cardiovascular Risk Factors in Women

edited by

Giuseppina Maura Francese

and

Lucio Giuseppe Granata

submission deadline 30 Nov 2026 | Viewed by 188 | Submission Open

Keywords: women’ s cardiovascular health; sex- and gender-specific risk; coronary artery disease in women; pregnancy-associated cardiovascular risk; peripartum cardiomyopathy; menopause and cardiovascular risk; psychosocial stress and depression; autoimmune disease in women; cardiometabolic risk

(This special issue belongs to the Section Epidemiology, Lifestyle, and Cardiovascular Health)

State of the Art in Mitral Valve Disease, 2nd Edition

edited by Gilles D. Dreyfus

submission deadline 30 Nov 2026 | Viewed by 176 | Submission Open

Keywords: mitral valve pathophysiology and echocardiography; mitral valve stenosis; mitral valve regurgitation (primary; secondary; atrial); standard vs minimally invasive mitral valve surgery; resection or no resection; TEER mitral valve “ repair” or treatment; TEER mitral valve replacement: which prosthesis for which patient?; mitral valve replacement; mitral valve repair failures: why?; the future of mitral valve regurgitation

(This special issue belongs to the Section Cardiac Surgery)

Advances in Catheter Ablation of Atrial Fibrillation: Techniques, Technologies, and Clinical Outcomes

edited by

Andrea Matteucci

and Claudio Pandozi

submission deadline 30 Nov 2026 | Viewed by 169 | Submission Open

Keywords: catheter ablation; atrial fibrillation; pulmonary vein isolation; cardiac mapping systems; ablation technologies; recurrence prevention; patient selection; clinical outcomes; quality of life

(This special issue belongs to the Section Electrophysiology and Cardiovascular Physiology)

Mitochondrial Function in the Pathophysiology of Cardiovascular Diseases

edited by

Alfonsas L. Vaǐnoras

, Gediminas Jarusevicius and Ganna Nevoit

submission deadline 30 Nov 2026 | Viewed by 117 | Submission Open

Keywords: mitochondria; mitochondrial dysfunction; cardiovascular diseases; coronary heart disease; hypertension; heart failure; vascular pathology; cardiomyopathy

(This special issue belongs to the Section Acquired Cardiovascular Disease)

Critical Care Cardiac Ultrasound and Haemodynamic Imaging: Standards, Practice, and Emerging Applications

edited by Antonio Rubino and Ashley Miller

submission deadline 30 Nov 2026 | Submission Open

Keywords: critical care ultrasound; point-of-care ultrasound; haemodynamic imaging; echocardiography; transoesophageal echocardiography; intensive care medicine; lung ultrasound; neuroPOCUS; haemodynamic monitoring; ultrasound education

(This special issue belongs to the Section Imaging)

Clinical Outcome and Treatment of Cardiac Arrest

edited by Tsukasa Yagi

submission deadline 31 Dec 2026 | 1 articles | Viewed by 2561 | Submission Open

Keywords: cardiac arrest; post-cardiac arrest syndrome; cardiogenic shock; post-cardiac-arrest care; resuscitation science

(This special issue belongs to the Section Electrophysiology and Cardiovascular Physiology)

Multimodal Cardiac Imaging: New and Controversial Insights

edited by

José Ángel Cabrera

and

Javier Urmeneta Ulloa

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1055 | Submission Open

Keywords: cardiac imaging; cardiac magnetic resonance; cardiac computed tomography; multimodal imaging

(This special issue belongs to the Section Imaging)

Acute Pulmonary Embolism: A Cardiovascular Emergency

edited by Claudio Picariello and Marco Zuin

submission deadline 31 Dec 2026 | 1 articles | Viewed by 413 | Submission Open

Keywords: thrombolysis ; catheter directed therapies ; direct oral anticoagulants ; risk stratification ; pulmonary embolism response team ; long-term anticoagulation

(This special issue belongs to the Section Acquired Cardiovascular Disease)

Lipid and Lipoprotein Metabolism in Cardiovascular Disease

edited by

Hajnalka Lőrincz

and

Mariann Harangi

submission deadline 31 Dec 2026 | Viewed by 328 | Submission Open

Keywords: lipoprotein; lipid metabolism; dyslipidemia; atherosclerosis; inflammation; oxidative stress; obesity; insulin resistance; myocardial infarction; stroke; lipid-lowering treatment; personalized medicine

(This special issue belongs to the Section Acquired Cardiovascular Disease)

Myocarditis and Inflammatory Cardiomyopathy: From Diagnosis to Treatment

edited by Marco Matteo Ciccone, Maria Cristina Carella and

Marco Maria Dicorato

submission deadline 31 Dec 2026 | Viewed by 199 | Submission Open

Keywords: myocarditis; inflammatory cardiomyopathy; inflammatory myocardial and pericardial syndromes; endomyocardial biopsy; cardiac magnetic resonance; multimodality imaging; heart failure; arrhythmias; immunomodulatory and immunosuppressive therapy; precision medicine

(This special issue belongs to the Section Acquired Cardiovascular Disease)

Contemporary Diagnosis and Management of Hypertensive Heart Disease: 2nd Edition

edited by

Jonathan Bella

and Alaa Mabrouk Salem Omar

submission deadline 31 Dec 2026 | Viewed by 124 | Submission Open

Keywords: hypertension; left ventricular hypertrophy; prognosis; genetics; echocardiography; non-invasive cardiac imaging; hypertension treatment; atrial fibrillation; heart failure; coronary artery disease

(This special issue belongs to the Section Acquired Cardiovascular Disease)

Cell Signaling in Cardiovascular Development, Homeostasis, and Disease Pathogenesis

edited by

Mohamad Azhar

and Irfan Kathiriya

submission deadline 31 Dec 2026 | Viewed by 79 | Submission Open

Keywords: cardiovascular disease; cardiovascular development; congenital heart defect; atherosclerosis; valvular heart disease; cancer cardiac cachexia; cardiomyopathy; aortic aneurysm

(This special issue belongs to the Section Cardiac Development and Regeneration)

Transcatheter Cardiovascular Interventions for Stroke Prevention

edited by

Anastasios Apostolos

submission deadline 31 Dec 2026 | Viewed by 66 | Submission Open

Keywords: PFO; LAA; ASD; cardioembolic stroke; embolism

(This special issue belongs to the Section Stroke and Cerebrovascular Disease)

Noninvasive Imaging in Cardiology: From Diagnosis to Treatment

edited by

Ching-Hui Sia

submission deadline 31 Jan 2027 | 1 articles | Viewed by 764 | Submission Open

Keywords: cardiac imaging; echocardiography; cardiac magnetic resonance; computed tomography; nuclear cardiology; artificial intelligence; risk stratification; diagnosis; therapy guidance; prognosis

(This special issue belongs to the Section Imaging)

Heart Development Defects: Focus on the Myoarchitecture of the Heart

edited by

Pierre Simon Jouk

submission deadline 31 Jan 2027 | Viewed by 227 | Submission Open

Keywords: heart myoarchitecture; computational anatomy; cardiac imaging; heart development defects

(This special issue belongs to the Section Pediatric Cardiology and Congenital Heart Disease)

Lifestyle Modifications and Their Impact on Coronary Artery Disease

edited by

Alberto Cordero

submission deadline 31 Jan 2027 | Viewed by 83 | Submission Open

Keywords: lifestyle; exercise; diet; cardiovascular disease; obesity; interventions

(This special issue belongs to the Section Epidemiology, Lifestyle, and Cardiovascular Health)

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