Hybrid Ablation of the Atrial Fibrillation

A special issue of Journal of Cardiovascular Development and Disease (ISSN 2308-3425). This special issue belongs to the section "Electrophysiology and Cardiovascular Physiology".

Deadline for manuscript submissions: 31 May 2025 | Viewed by 374

Special Issue Editor


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Guest Editor
Department of Cardiology, S. Chiara Hospital, 38122 Trento, Italy
Interests: interventional cardiology; electrophysiology; arrhythmias

Special Issue Information

Dear colleague,

Atrial fibrillation is the most frequent supraventricular arrhythmia in clinical practice. The therapeutic approach is generally directed to restore, when possible, normal heart rhythm and prevent related thromboembolic phenomena; however, clinical scenarios can be very complex and therefore require a multidisciplinary strategy.

The AF Heart Team proposed in the ESC 2024 guidelines is a team composed of a clinical cardiologist, an electrophysiologist, and a cardiac surgeon who collaborate and try to propose the best therapeutic strategy to the patient. Hybrid ablation of atrial fibrillation is an innovative therapeutic opportunity for the patient that aims to overcome the limitations of transcatheter ablation alone or surgical ablation alone. The purpose of this Special Issue is to deepen the subject considering rationale, techniques, results, complications, and future prospectives.

I would like to invite you to submit a paper to this Special Issue. Considering your expertise in the topic, I would be grateful if you could contribute one or two papers. I believe it is very important to promote knowledge of the hybrid ablation procedure for the treatment of atrial fibrillation considering the publication of the latest ESC guidelines and dedicated trials.

Dr. Massimiliano Marini
Guest Editor

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Keywords

  • atrial fibrillation
  • ablation
  • hybrid ablation
  • techniques
  • videothoracoscopic approach

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Published Papers (1 paper)

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Research

13 pages, 1708 KiB  
Article
Patients with Gastrointestinal Bleeding and Atrial Fibrillation: Potential Ideal Target for Epicardial Appendage Occlusion
by Stefano Branzoli, Massimiliano Marini, Domenico Catanzariti, Cecilia Pravadelli, Luigi Pannone, Giovanni D’Onghia, Mauro Fantinel, Fabrizio Guarracini, Gaia Franceschini, Mirco Zadro, Giulia Baroni, Silvia Casagrande, Donatella Ottaviani, Renato Turco, Serena Nicolussi Paolaz, Luciano Annicchiarico, Francesco Corsini, Roberto Rordorf, Kausilia Krishnadath, Flavia Ravelli, Carlo de Asmundis and Mark La Meiradd Show full author list remove Hide full author list
J. Cardiovasc. Dev. Dis. 2025, 12(5), 173; https://doi.org/10.3390/jcdd12050173 - 1 May 2025
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Abstract
Background: Gastrointestinal bleeding in patients with atrial fibrillation is an indication for left appendage occlusion. All endovascular devices mandate antithrombotic therapies: rebleeding risk remains an issue. To date, there are no reports on gastrointestinal rebleeding and stroke prevention by left appendage occlusion without [...] Read more.
Background: Gastrointestinal bleeding in patients with atrial fibrillation is an indication for left appendage occlusion. All endovascular devices mandate antithrombotic therapies: rebleeding risk remains an issue. To date, there are no reports on gastrointestinal rebleeding and stroke prevention by left appendage occlusion without any antithrombotic therapy in this category of patients. Methods: A total of 129 patients (male 85, mean age 76.6 ± 7.1, CHA2DS2Vasc 3.8 ± 1.5, HASBLED 3.3 ± 1.0; upper GI bleeding 10%, lower GI bleeding 86%, obscure occult 4.6%, on NOACS full dose 77.5%, NOACs reduced dose 13.1%, on anti-vitamin K 9.3%) with atrial fibrillation and history of repetitive gastrointestinal bleeding from ten centers underwent standalone thoracoscopic epicardial appendage closure without antithrombotic therapy for the entire follow up. Results: The observed bleeding rate was 0.91 events per year, equivalent to a relative risk of RR = 0.17 (p = 0.02) and a relative risk reduction (RRR) of 83%. The observed relative risk of stroke was 0.91 events per year, with a relative risk of RR = 0.19 (p = 0.03) and a relative risk reduction (RRR) of 81%. Conclusion: Standalone epicardial appendage occlusion without antithrombotic therapy in patients with repetitive gastrointestinal bleeding is safe and promising when rebleeding and stroke risk reduction need to be optimized. Full article
(This article belongs to the Special Issue Hybrid Ablation of the Atrial Fibrillation)
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