International Journal of Molecular Sciences

Diverse Biomolecular Probes in the Development of Single-Molecule Biosensors

edited by

Kevin D. Belfield

and

Xiaohan Chen

submission deadline 30 Sep 2026 | Viewed by 531 | Submission Open

Keywords: biomolecular probes; single-molecule method; biosensors; diseases diagnosis; biomarkers; nanotechnology

(This special issue belongs to the Section Materials Science)

Molecular Advances of Gut–Brain Communications

edited by

Walter Pirovano

submission deadline 30 Sep 2026 | Viewed by 528 | Submission Open

Keywords: gut-brain axis; microbiome; molecular profiling; omics/multi-omics data; functional measurements; analytical methods; computational methods; neurological disorders; neuropsychiatric disorders

(This special issue belongs to the Section Molecular Biology)

Omega-6 and Omega-3 Fatty Acid Imbalance: Roles in Human Health and Pathogenesis of Diseases

edited by

Jing X. Kang

submission deadline 30 Sep 2026 | Viewed by 518 | Submission Open

Keywords: omega-6/omega-3 ratio; omega-6 fatty acids; omega-3 fatty acids; omega-6/omega-3 imbalance; lipid metabolism; inflammation; chronic diseases; cardiovascular disease; cancer; metabolic syndrome; neurodegenerative diseases; autoimmune diseases; nutritional interventions; polyunsaturated fatty acids (PUFAs); molecular mechanisms; disease pathogenesis; disease management; health promotion

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Cellular Pathways and Cytokine Networks in Tuberous Sclerosis: Mechanisms and Therapeutic Targets

edited by Uchenna John Unachukwu

submission deadline 30 Sep 2026 | Viewed by 512 | Submission Open

Keywords: mTOR signaling dysregulation; neurocristopathy; cytokine crosstalk; TSC1/TSC2 complex; epigenetic modifiers; metabolic reprogramming; molecular biomarkers; spatial transcriptomics

(This special issue belongs to the Section Molecular Biology)

Patient-Derived iPSC Models in Chronic Disease Research

edited by

Valentina Parra

submission deadline 30 Sep 2026 | Viewed by 482 | Submission Open

Keywords: induced pluripotent stem cells; patient-derived iPSCs; chronic diseases; disease modeling; molecular mechanisms; stem cell differentiation; gene editing; organoids; personalized medicine; multi-omics

(This special issue belongs to the Section Molecular Biology)

Molecular Mechanisms of Gut Microbiota-Mediated Drug Efficacy and Toxicity

edited by

Jin-Yi Wan

submission deadline 30 Sep 2026 | Viewed by 463 | Submission Open

Keywords: gut microbiota; pharmacomicrobiomics; drug metabolism; drug toxicity; drug efficacy; xenobiotic biotransformation; precision medicine; cancer immunotherapy; fecal microbiota transplantation; host–microbiome interactions

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Novel Molecular Pathways and Therapeutic Strategies in Atherosclerotic Cardiovascular Disease

edited by

Elisabeta Badila

and Catalin Adrian Buzea

submission deadline 30 Sep 2026 | Viewed by 458 | Submission Open

Keywords: atherogenesis; vascular inflammation; immune modulation; lipid metabolism; clonal hematopoiesis (CHIP); endothelial dysfunction; plaque instability; epigenetic regulation; molecular signaling pathways; precision cardiovascular medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Insights Into the Toxicology of Heavy Metals

edited by

Di Ran

submission deadline 30 Sep 2026 | 1 articles | Viewed by 436 | Submission Open

Keywords: heavy metal toxicology; environmental exposure; gut microbiome; mitochondrial dysfunction

(This special issue belongs to the Section Molecular Toxicology)

Inflammatory Bowel Disease and Cardiometabolic Comorbidities: Molecular Mechanisms and Therapeutic Perspectives

edited by

Dimitrios Patoulias

and

Christos Mademlis

submission deadline 30 Sep 2026 | Viewed by 425 | Submission Open

Keywords: cardiovascular–kidney–metabolic syndrome; diabetes; obesity; cardiovascular disease; inflammatory bowel disease; Crohn’s disease; ulcerative colitis; inflammation; endothelial dysfunction

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Genome-Wide Association Studies of Complex Diseases and Related Endophenotypes and Biomarkers

edited by M. Ilyas Kamboh

submission deadline 30 Sep 2026 | Viewed by 423 | Submission Open

Keywords: genome-wide association studies; complex diseases; endophenotypes; biomarkers; rare variants; copy number variants; diverse populations

(This special issue belongs to the Section Molecular Genetics and Genomics)

Novel Insights into Endothelial Cell Biology

edited by

Takato Hara

and

Toshiyuki Kaji

submission deadline 30 Sep 2026 | Viewed by 414 | Submission Open

Keywords: endothelial cell heterogeneity; mechanotransduction; endothelial–immune interactions; endothelial senescence; vascular barrier regulation; extracellular vesicles; angiogenesis and vascular remodeling; endothelial metabolism; endothelial regulation of the fibrinolytic system

(This special issue belongs to the Section Molecular Biology)

Integrating Multi-Omics Approaches in Fish Immunology to Improve Aquaculture Sustainability

edited by

Parasuraman Aiya Subramani

submission deadline 30 Sep 2026 | Viewed by 412 | Submission Open

Keywords: machine learning; network analysis; vaccine development; genomic selection; single-cell RNA-seq; meta-analysis; innate immunity; biomarker discovery

(This special issue belongs to the Section Molecular Immunology)

Molecular Interplay: Natural Antioxidants as Modulators of Redox Homeostasis

edited by

Giovanni Pratelli

and

Daniela Carlisi

submission deadline 30 Sep 2026 | Viewed by 400 | Submission Open

Keywords: natural antioxidants; oxidative stress; chronic diseases; molecular mechanisms; cancer; neurodegenerative diseases; metabolic disorders; redox biology; omics; precision medicine

(This special issue belongs to the Section Molecular Biology)

Genetic Diversity, Founder Effects, and Migration in Neurodegeneration: Molecular and Population Perspectives

edited by

Dasiel Oscar Borroto-Escuela

submission deadline 30 Sep 2026 | Viewed by 398 | Submission Open

Keywords: neurodegeneration; population genetics; founder effects; genetic diversity; migration and disease risk; spinocerebellar ataxia; Alzheimer’s disease; Parkinson’s disease; genetic epidemiology; underrepresented populations

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Advances in Pituitary Neuroendocrine Tumors: From Growth Control to Plasticity and Evolutionary Pathogenesis

edited by Ana Lucía De Paul and Liliana del Valle Sosa

submission deadline 30 Sep 2026 | Viewed by 379 | Submission Open

Keywords: tumor heterogeneity; tumor biomarkers; transcriptomics; molecular neuroscience; clinical treatment; pathogenesis; pituitary neuroendocrine tumors; neuroendocrine tumors; nonfunctional; PIT1; pituitary adenoma

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Role of Bifunctional Antibodies in Human Cancer

edited by

Alessandro Canella

submission deadline 30 Sep 2026 | Viewed by 378 | Submission Open

Keywords: bispecific antibodies; tumor immune microenvironment (TIME); cancer immunotherapy; tumor associated antigens; biomarker discovery; T cell engagers (BiTEs, TriTEs, TriKEs); dual affinity retargeting antibodies (DARTs); Fc engineering and FcγR modulation; tumor associated antigen (TAA) avidity optimization; immune reprogramming; bispecific antibody pharmacokinetics and biodistribution; antibody–drug conjugate (ADC) hybrid formats; bifunctional antibodies

(This special issue belongs to the Section Molecular Oncology)

Molecular Studies of Cartilage Deformation

edited by

Kazuo Yudoh

submission deadline 30 Sep 2026 | Viewed by 375 | Submission Open

Keywords: osteoarthritis; chondrocyte; mitochondria function; mechanical stress; oxidative stress; cartilage metabolism

(This special issue belongs to the Section Molecular Biology)

Current Trends in Nanophotonics and Molecular-Scale Light Control

edited by Mitradeep Sarkar

submission deadline 30 Sep 2026 | Viewed by 367 | Submission Open

Keywords: nanophotonics; light–matter interaction; metamaterials and 2D materials; photonic crystals; molecular sensing and imaging; quantum and nonlinear optics

(This special issue belongs to the Section Molecular Nanoscience)

Procoagulant Platelets in Vascular Disease and Beyond

edited by

Paresh P. Kulkarni

submission deadline 30 Sep 2026 | Viewed by 361 | Submission Open

Keywords: procoagulant platelets; thrombosis; hemostasis; coagulation; bleeding; vascular disease; cancer; cardiometabolic syndrome; inflammation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

TRIM Family Proteins and Beyond: Molecular Mechanisms in Tissue Homeostasis and Disease

edited by

Chuanxi Cai

submission deadline 30 Sep 2026 | Viewed by 358 | Submission Open

Keywords: TRIM family proteins; E3 ubiquitin ligases; protein homeostasis; autophagy and selective autophagy; innate immunity and antiviral defense; signal transduction; post-translational modifications; phase separation; tissue homeostasis; cancer biology; heart failure; neurodegeneration; inflammation and immunity; molecular mechanisms of disease; biomarkers and therapeutic targets

(This special issue belongs to the Section Molecular Biology)

Regulatory T Cells and Immune Tolerance: From Nobel Discoveries to Clinical Breakthroughs

edited by Raquel López-Mejías

submission deadline 30 Sep 2026 | Viewed by 355 | Submission Open

Keywords: regulatory T cells (Tregs); immune tolerance; FOXP3 gene; therapies; immunotherapy

(This special issue belongs to the Section Molecular Immunology)

Biological Effects and Toxicity of Nanomaterials

edited by Lucyna Kapka-Skrzypczak

submission deadline 30 Sep 2026 | Viewed by 351 | Submission Open

Keywords: nanotoxicology; nanomaterials; biological effects; cytotoxicity; oxidative stress; inflammation; genotoxicity; immunotoxicity; risk assessment; nanosafety; nanomedicine; environmental health; in vitro models; in vivo studies

(This special issue belongs to the Section Molecular Nanoscience)

Future Perspective and Challenge of Nanomaterials

edited by

Antreas Afantitis

submission deadline 30 Sep 2026 | Viewed by 345 | Submission Open

Keywords: nanomaterial; nanoinformatics; materials informatics; functional material; molecular dynamics

(This special issue belongs to the Section Molecular Nanoscience)

Targeted Therapies and Chemoresistance in Gastrointestinal Cancers

edited by Zheng Chen

submission deadline 30 Sep 2026 | Viewed by 343 | Submission Open

Keywords: gastrointestinal cancer; targeted therapy; chemoresistance; drug resistance; precision medicine; molecular biomarkers; signal transduction; tumor microenvironment; immunotherapy; novel therapeutics

(This special issue belongs to the Section Molecular Oncology)

Advances in Cell Signaling Pathways and Signal Transduction, 2nd Edition

edited by

Susumu Ohya

and Katsuhiko Muraki

submission deadline 30 Sep 2026 | Viewed by 337 | Submission Open

Keywords: signaling pathway; signal transduction; cell biology; signal transduction; cell communication; cell signaling

(This special issue belongs to the Section Biochemistry)

Molecular Immunity to Parasitic Infections

edited by Jamie A. Whitelaw and Stuart Woods

submission deadline 30 Sep 2026 | Viewed by 334 | Submission Open

Keywords: parasitology; immunology; vaccines; cell therapy; gene editing; parasitic diseases; immune responses; inflammation; molecular mechanisms; immune evasion; host cell invasion and manipulation

(This special issue belongs to the Section Molecular Immunology)

Molecular Genetics in Metabolic Syndrome and Diabetes

edited by

Marijn Speeckaert

submission deadline 30 Sep 2026 | Viewed by 328 | Submission Open

Keywords: metabolic syndrome; diabetes mellitus; genetic variants; epigenetics; insulin resistance; obesity; dyslipidemia; inflammation; oxidative stress; mitochondrial dysfunction; non-coding RNAs; transcriptomics; proteomics

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

State-of-the-Art Molecular Plant Sciences in Thailand

edited by

Mayura Veerana

submission deadline 30 Sep 2026 | Viewed by 323 | Submission Open

Keywords: molecular plant sciences; plant biotechnology; functional genomics; molecular breeding; plant stress responses; omics technologies; plant–microbe interactions; sustainable agriculture; crop improvement

(This special issue belongs to the Section Molecular Plant Sciences)

Multiscale Toxicology: From Cell Models to Whole Organisms

edited by

Elvira Brunelli

and

Rachele Macirella

submission deadline 30 Sep 2026 | Viewed by 309 | Submission Open

Keywords: toxicology; ecotoxicology; environmental risk assessment; multiscale toxicology; emerging contaminants; sentinel species; omics; mixture toxicity

(This special issue belongs to the Section Molecular Toxicology)

Molecular Basis of Rare Diseases and Functional Variant Interpretation

edited by

Adrijan Sarajlija

submission deadline 30 Sep 2026 | Viewed by 305 | Submission Open

Keywords: rare diseases; functional variant interpretation; variants of uncertain significance; molecular pathogenesis; functional assays; genotype–phenotype correlation; multiomics; clinical genetics

(This special issue belongs to the Section Molecular Genetics and Genomics)

From Soil to Gut: Molecular Mechanisms of Microbial Remediation for Planetary and Human Health

edited by

Yi Yang

, Hao Zhou and

Xin Jin

submission deadline 30 Sep 2026 | Viewed by 296 | Submission Open

Keywords: microbiome restoration; biotherapeutic agents; in vivo/vitro detoxification; dysbiosis rescue; synthetic consortia; host-microbe interactions; bioremediation; ecohealth

(This special issue belongs to the Section Molecular Microbiology)

Advances in Genetics of Human Reproduction—2nd Edition

edited by

Jasenka Wagner

and

Borut Peterlin

submission deadline 30 Sep 2026 | Viewed by 292 | Submission Open

Keywords: genetic; human reproduction; infertility; medically assisted reproduction; pregnancy complications; recurrent miscarriage

(This special issue belongs to the Section Molecular Genetics and Genomics)

Non-Coding RNAs as Key Players in Cancer Biology and Clinical Translation

edited by

Ana Cristina Gonçalves

,

Raquel Alves

and

Ana Bela Sarmento Ribeiro

submission deadline 30 Sep 2026 | Viewed by 292 | Submission Open

Keywords: non-coding RNAs; microRNAs; long non-coding RNAs; circular RNAs; RNA-based therapeutics; RNA delivery; systems; liquid biopsy; predictive biomarkers; drug resistance; clinical translation

(This special issue belongs to the Section Molecular Oncology)

Enhancing Plant Traits Through In Vitro Culture

edited by Jacek Gawroński

submission deadline 30 Sep 2026 | Viewed by 290 | Submission Open

Keywords: plant tissue culture; somatic embryogenesis; organogenesis; micropropagation; callus culture; in vitro regeneration; in vitro mutagenesis; haploid and doubled haploid production; molecular markers; genetic analysis; genomics; transcriptomics; epigenetic regulation; proteomic profiling; molecular mechanisms; gene expression analysis

(This special issue belongs to the Section Molecular Plant Sciences)

Interactions Between Rhizosphere Microbiota and Plants

edited by

Anna Gałązka

submission deadline 30 Sep 2026 | Viewed by 287 | Submission Open

Keywords: microbiome and mycobiome of soil and plant rhizosphere; endorhizosphere; next-generation sequencing; soil and plant biodiversity

(This special issue belongs to the Section Molecular Plant Sciences)

Advances in Xenobiotic Toxicity: From Transcriptional Regulation to Reproductive and Behavioural Impacts

edited by Sylwia Swigonska

submission deadline 30 Sep 2026 | Viewed by 283 | Submission Open

Keywords: xenobiotic interactions; molecular mechanisms of toxicity; reproductive toxicology; early biomarkers; emerging contaminants; neurobehavioral toxicity; microbiota–xenobiotic interactions; biomolecular responses; environmental health; molecular toxicology

(This special issue belongs to the Section Molecular Toxicology)

Plant–Microbe Interactions: The Battle for Plant Infection and Prevention

edited by

Rezaee Danesh Younes

submission deadline 30 Sep 2026 | Viewed by 282 | Submission Open

Keywords: plant–microbe interactions; plant immunity; pathogen virulence; microbiome; biological control; trichoderma; arbuscular mycorrhizal fungi; omics technologies; RNA-based disease control; genome editing; sustainable agriculture; plant protection; microbial ecology; systems biology

(This special issue belongs to the Section Molecular Plant Sciences)

Activation and Suppression of Plant Immunity

edited by

Loredana Maria Scalschi

, Eugenio Llorens and

Ana Isabel González-Hernández

submission deadline 30 Sep 2026 | Viewed by 280 | Submission Open

Keywords: plant immunity; plant–pathogen interactions; effector biology; resistance mechanisms; signaling pathways; crop protection; sustainable agriculture

(This special issue belongs to the Section Molecular Plant Sciences)

Cellular and Molecular Mechanisms of Plaque Development and Progression

edited by

Ida Daniela Perrotta

submission deadline 30 Sep 2026 | Viewed by 271 | Submission Open

Keywords: atherosclerosis; atherosclerotic plaque; endothelial dysfunction; vascular inflammation; macrophage polarization; smooth muscle cell phenotypic switching; lipid metabolism; oxidative stress; extracellular vesicles; epigenetic regulation; immune–vascular interactions; plaque instability

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Neurochemical and Biochemical Mechanisms of Depressive Disorders

edited by

Ana B. Ramos-Hryb

and Mauricio Peña Cunha

submission deadline 30 Sep 2026 | Viewed by 269 | Submission Open

Keywords: neurochemical signaling; molecular psychiatry; biochemical biomarkers; synaptic plasticity; neuroinflammation; oxidative stress; glutamatergic system; proteomics and metabolomics; signal transduction; neuroendocrine

(This special issue belongs to the Section Molecular Neurobiology)

Genetics and Molecular Therapies in Common Age-Related and Inherited Retinal Diseases

edited by

Xiaoming Gong

submission deadline 30 Sep 2026 | Viewed by 267 | Submission Open

Keywords: inherited retinal diseases; molecular diagnosis; age-related retinal degeneration; genotype–phenotype correlations; gene and cell therapies; early biomarkers of retinal disease; AI‑driven analytics

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Applicability of Graphene-Based Materials in the Pharmaceutical, Biological and Biomedical Sectors, 2nd Edition

edited by

Lidia Magerusan

submission deadline 30 Sep 2026 | Viewed by 264 | Submission Open

Keywords: graphene; graphene-based composites; graphene-based sensors; biomedical applications; tissue engineering; drug delivery

(This special issue belongs to the Section Molecular Nanoscience)

Cardiac Protein Metabolism in Health and Diseases

edited by

Anindhya Sundar Das

submission deadline 30 Sep 2026 | Viewed by 263 | Submission Open

Keywords: cardiac proteostasis; translational regulation; protein synthesis; ubiquitin–proteasome system; autophagy; cardiac remodeling; cardiomyopathy; RNA biology; protein quality control

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Nuclear Receptor-Mediated Signal Transduction

edited by

Elza Sofia Silva Fonseca

submission deadline 30 Sep 2026 | Viewed by 257 | Submission Open

Keywords: transcriptional regulation; non-genomic signalling; environmental signalling; endocrine disruption; nuclear receptor crosstalk; coregulators; modulators; evolution

(This special issue belongs to the Section Biochemistry)

Molecular Advances in Human Leukocyte Antigen (HLA)

edited by Inaki Alvarez

submission deadline 30 Sep 2026 | Viewed by 255 | Submission Open

Keywords: HLA; immunopeptidome; antigen presentation; antigen processing; mass spectrometry

(This special issue belongs to the Section Molecular Immunology)

Quantitative Physiology of Mitochondria: Integration of Theory, Computation and High-Throughput Experimentation

edited by

Tsz-Leung To

submission deadline 30 Sep 2026 | Viewed by 254 | Submission Open

Keywords: mitochondria; systems biology; quantitative physiology; multi-omics; computational modeling; bioenergetics; thermodynamics and kinetics; metabolic networks; physicochemical modeling; virtual cells

(This special issue belongs to the Section Molecular Biology)

Development and Application of Novel Bio-Based Food Packaging Materials

edited by

Oscar Zannou

submission deadline 30 Sep 2026 | Viewed by 253 | Submission Open

Keywords: bio-based polymers; active and intelligent packaging; biodegradable materials; food preservation technologies; sustainable packaging systems

(This special issue belongs to the Section Materials Science)

Molecular Insights and Innovative Materials in Prosthodontics and Oral Implantology

edited by Ángel-Orión Salgado-Peralvo

submission deadline 30 Sep 2026 | Viewed by 253 | Submission Open

Keywords: dental implants; dental prosthesis, implant-supported; osseointegration; dental implantation; bone regeneration

(This special issue belongs to the Section Materials Science)

Metabolic Reprogramming in Cancer: Non-Coding RNAs as Regulators and Biomarkers

edited by

Christos Papaneophytou

submission deadline 30 Sep 2026 | Viewed by 250 | Submission Open

Keywords: metabolic enzymes; circulating biomarkers; non-coding RNAs; circulating free DNA; liquid biopsy; metabolic reprogramming; artificial intelligence; biomarker discovery; precision medicine

(This special issue belongs to the Section Molecular Biology)

Chemical Bonds and Molecular Shapes

edited by

SeyedAbdolreza Sadjadi

submission deadline 30 Sep 2026 | Viewed by 241 | Submission Open

Keywords: chemical bonds; molecular shapes; molecular sciences; atoms and molecules; graphical chemistry

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

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