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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Toxicology Research: Understanding and Predicting Compound-Induced Toxicity

edited by

Miriam Beatríz Virgolini

submission deadline 30 Nov 2025 | 1 articles | Viewed by 926 | Submission Open

Keywords: toxicity; adverse-outcome pathway; metals; pesticides; drugs of abuse; pharmaceuticals

(This special issue belongs to the Section Molecular Toxicology)

Nanoparticle-Based Biosensors and Their Applications

edited by

Edyta Proniewicz

submission deadline 30 Nov 2025 | 1 articles | Viewed by 917 | Submission Open

Keywords: biosensors; metal nanoparticles (MNPs); synthesis methods; molecular spectroscopy characteristics; molecular medicine; molecular biology

(This special issue belongs to the Section Molecular Nanoscience)

Trace Elements, Metal Ions, Channels and Transporters in Metabolism

edited by

Maria Maares

submission deadline 30 Nov 2025 | 1 articles | Viewed by 901 | Submission Open

Keywords: cancer; cardiac dysfunction; enzyme function; metabolism; metal ions; neurologic disorders; pathophysiology; trace elements

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Intrinsically Disordered Proteins (IDPs): From Structure to Mechanism and Function

edited by

Kyouhoon Han

submission deadline 30 Nov 2025 | Viewed by 866 | Submission Open

Keywords: IDP; NMR; completely unstructured; pre-structured; PreSMo; target binding

(This special issue belongs to the Section Biochemistry)

Molecular Mechanisms in Mitochondria-Targeted Drug Delivery System

edited by

Maria Manuel Oliveira

and

Francisco Peixoto

submission deadline 30 Nov 2025 | Viewed by 825 | Submission Open

Keywords: mitochondria; mitochondrial diseases; nanoformulations; therapeutic agents; drug release; precision medicine

(This special issue belongs to the Section Molecular Pharmacology)

Analyzing the Molecular Mechanisms of Plant Disease Pathogenesis and Host Disease Resistance

edited by Zhibing Wu

submission deadline 30 Nov 2025 | 1 articles | Viewed by 788 | Submission Open

Keywords: pathogenicity mechanisms; plant– pathogen interactions; plant immunity; effector biology; resistance genes; multi-omics approaches; nanotechnology in plant protection

(This special issue belongs to the Section Molecular Plant Sciences)

Protein–Protein Interactions in Human Cancer

edited by

Geng Wu

submission deadline 30 Nov 2025 | 1 articles | Viewed by 786 | Submission Open

Keywords: protein– protein interactions; protein– protein complexes; human cancer; signal transduction pathways; protein structure and function

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Environmental Pollutants Exposure and Toxicity

edited by

Tzveta Georgieva

submission deadline 30 Nov 2025 | 1 articles | Viewed by 782 | Submission Open

Keywords: environmental pollutants exposure assessment; molecular methods; biomarkers; human safety; environmental safety

(This special issue belongs to the Section Molecular Toxicology)

Supplements and Drug-Based Strategies in Neonatal and Paediatric Health

edited by

Giulia Malaguarnera

submission deadline 30 Nov 2025 | Viewed by 763 | Submission Open

Keywords: neonatal pharmacology; paediatric supplements; nutraceuticals in early life; microbiota– host interactions; infectious diseases in children; neurodevelopmental disorders; drug– nutrient interactions; dosing and delivery routes; molecular paediatrics; critical analysis of paediatric interventions

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Signaling and Cellular Mechanisms in Asthma

edited by

Kapil Sirohi

submission deadline 30 Nov 2025 | 1 articles | Viewed by 744 | Submission Open

Keywords: asthma; endotypes; pausi-immune asthma; nonatopic asthma; steroid insensitivity; neutrophilic asthma; innate lymphoid cells; Th2 cells

(This special issue belongs to the Section Molecular Immunology)

Canonical and Noncanonical Inflammasomes in Inflammation and Diseases

edited by

Young-Su Yi

submission deadline 30 Nov 2025 | 1 articles | Viewed by 730 | Submission Open

Keywords: canonical; noncanonical; inflammasome; inflammation; human diseases; anti-inflammatory therapeutics

(This special issue belongs to the Section Molecular Immunology)

Molecular View of Natural Products with Antiviral Effects

edited by

Jin-ching Lee

submission deadline 30 Nov 2025 | 1 articles | Viewed by 715 | Submission Open

Keywords: virus; phytochemicals; nutritional supplements; marine extracts; antioxidants

(This special issue belongs to the Section Molecular Microbiology)

The Molecular and Cellular Pathophysiologic Mechanisms Underlying Ocular Diseases and Emerging Therapies (2nd Edition)

edited by

Snježana Kaštelan

submission deadline 30 Nov 2025 | 1 articles | Viewed by 705 | Submission Open

Keywords: eye disease; immunobiological features; molecular pathogenesis; biomarkers; clinical implications; emerging therapies; lacrimal gland; ocular tumors; glaucoma; diabetic retinopathy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Natural Antioxidants—Sources, Characteristics, and Biological Activity

edited by

Maciej Spiegel

submission deadline 30 Nov 2025 | 1 articles | Viewed by 698 | Submission Open

Keywords: natural antioxidants; oxidative stress; reactive oxygen species; inflammation; free radicals; structure– activity relationship; nutraceuticals; synergistic effects; plant-derived compounds; drug discovery

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Targeting Epigenetic Complexes and Alternative Protein Degradation Pathways in Medicinal Chemistry

edited by Jean Leandro Dos Santos

submission deadline 30 Nov 2025 | 1 articles | Viewed by 695 | Submission Open

Keywords: protein degradation; LYTAC; AUTAC; ATTEC; epigenetics; NuRD; HDAC; BRD; SWI/SNF; PRC2; chromatin; conjugates; lysosome; autophagy; drug discovery

(This special issue belongs to the Section Biochemistry)

Diversity in Structure, Function, and Regulation of Calcium-Permeable Channels

edited by

Lucie Parent

submission deadline 30 Nov 2025 | Viewed by 636 | Submission Open

Keywords: calcium-permeable channels in health and disease; calcium-permeable channels in calcium cycling; TRP channels; voltage-gated calcium channels; STIM / Orai complexes; intracellular IP3 calcium channels; intracellular RyR calcium channels; posttranslational calcium channel modifications; calcium-permeable channel inhibitors; calcium-permeable channel biophysics; calcium-permeable channel evolution

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Cutting-Edge Advances in Natural Bioactive Compounds

edited by

Joachim Storsberg

submission deadline 30 Nov 2025 | Viewed by 623 | Submission Open

Keywords: natural bioactive compounds; phytochemicals; fungal metabolites; antioxidant activity; anti-inflammatory agents; antimicrobial compounds; anti-cancer compounds

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Macrophage Polarization and Human Inflammatory Diseases

edited by

Mary Cloud B. Ammons

submission deadline 30 Nov 2025 | Viewed by 594 | Submission Open

Keywords: macrophage polarization; inflammation; metabolic immunomodulation; epigenetics; in vitro models; in vivo models; diagnostics; therapeutics; infectious disease; metabolic disease

(This special issue belongs to the Section Molecular Pharmacology)

Research in Genetic Causes of Adult-Onset Disorders

edited by

Claudio Graziano

submission deadline 30 Nov 2025 | Viewed by 591 | Submission Open

Keywords: ADPKD; cardiomyopathy; CADASIL; amyloidosis; MODY; late-onset hearing impairment; penetrance; adult onset

(This special issue belongs to the Section Molecular Genetics and Genomics)

Advances in Fluorescent Sensors

edited by

Levente Cseri

and

Ervin Kovács

submission deadline 30 Nov 2025 | 1 articles | Viewed by 563 | Submission Open

Keywords: fluorescence probe; fluorescent nanomaterials; analyte recognition; fluorescence imaging; real-time monitoring; photoinduced electron transfer; Fö rster resonance energy transfer; genetically encoded indicators; sensor devices; fluorescence microscopy

(This special issue belongs to the Section Materials Science)

Sarcomas: From Molecular Signatures to Morphologic Patterns

edited by

Isidro Machado

submission deadline 30 Nov 2025 | 1 articles | Viewed by 545 | Submission Open

Keywords: sarcomas; histopathology; molecular pathology; FISH; gene fusion in sarcomas

(This special issue belongs to the Section Molecular Oncology)

Oral Potentially Malignant Disorders and Oral Cancers: From Molecular Pathology to Therapeutic Approaches

edited by

Ana Caruntu

and Nicholas Kalavrezos

submission deadline 30 Nov 2025 | 1 articles | Viewed by 515 | Submission Open

Keywords: oral cancer; oral potentially malignant disorders; molecular mechanisms in oral cancer; detection of oral cancer; pathogenic mechanisms of oral cancer; immune system; translational oral cancer; microbiota oral cancer; therapy for oral cancer

(This special issue belongs to the Section Molecular Oncology)

Molecular Mechanisms of Gastrointestinal Immunity: Balancing Homeostasis and Pathological States

edited by Mihai Danciu and Gabriel Becheanu

submission deadline 30 Nov 2025 | Viewed by 511 | Submission Open

Keywords: gastrointestinal immunity; mucosal barrier function; immune signaling pathways; gut microbiota; inflammatory bowel disease (IBD); colorectal cancer; cytokines and chemokines; immunopathology; targeted immunotherapy; biomarkers of gut inflammation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Aspects of Viral Pathogenesis: From Infection to Host Response

edited by

Quang Duy Trinh

submission deadline 30 Nov 2025 | 1 articles | Viewed by 484 | Submission Open

Keywords: viruses; viral pathogenesis; virus– host interaction; molecular virology; immunity; viral entry; viral replication; emerging viruses; infectious diseases; inflammation

(This special issue belongs to the Section Molecular Microbiology)

New Advances in Metal Nanoparticles

edited by

Emilia Konował

submission deadline 30 Nov 2025 | 1 articles | Viewed by 482 | Submission Open

Keywords: metal nanoparticles; molecular-level mechanisms; functional nanostructures; environmental nanotechnology; nanoparticle stability; catalysis; hybrid nanomaterials; bimetallic systems; ligand– nanoparticle interactions

(This special issue belongs to the Section Molecular Nanoscience)

Toxicomicrobiomics: Exploring the Interplays Between Xenobiotics, Gut Microbiota, and Health

edited by

Ana López Moreno

and

Alicia Ruiz-Rodríguez

submission deadline 30 Nov 2025 | Viewed by 428 | Submission Open

Keywords: xenobiotics; gut microbiota; human health; harmful substances; toxic/mutagenic compounds

(This special issue belongs to the Section Molecular Microbiology)

Molecular-Scale Design and Applications of Food Packaging: Eco-Friendly Materials and Technologies

edited by

Xi Yu

and

Tian Zhong

submission deadline 30 Nov 2025 | Viewed by 404 | Submission Open

Keywords: sustainable packaging; biodegradable materials; smart packaging; active packaging; food safety; environmental impact

(This special issue belongs to the Section Materials Science)

New Perspectives in 3D Bioprinting

edited by Pamela Mozetic and

Alessio Bucciarelli

submission deadline 30 Nov 2025 | Viewed by 397 | Submission Open

Keywords: 3D bioprinting; regenerative medicine; pluripotent stem cells; disease modeling; precision medicine

(This special issue belongs to the Section Materials Science)

Genetic Considerations in the Evolving Treatment Landscape of Hormone-Sensitive and Hormone-Resistant Prostate Cancer

edited by

Pierre Tennstedt

submission deadline 30 Nov 2025 | Viewed by 395 | Submission Open

Keywords: prostate cancer; hormone-sensitive prostate cancer; HSPC; hormone-resistant prostate cancer; HRPC; metastasis; androgen deprivation therapy; docetaxel; androgen receptor axis-targeted therapy agents; ARAT; abiraterone; enzalutamide; apalutamide; talazoparib; genetic; biomarker; liquid biopsy

(This special issue belongs to the Section Molecular Oncology)

Progress in Prevention and Treatment of Cardiovascular Diseases and Arrhythmias

edited by

Narcis Tribulova

submission deadline 30 Nov 2025 | 1 articles | Viewed by 368 | Submission Open

Keywords: translational research; novel animal models; novel treatment targets; pleiotropic drugs; harnessing of molecular H

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Genomic and Proteomic Advances in Tracking Antibiotic Resistance Evolution

edited by

Vanessa Silva

submission deadline 30 Nov 2025 | Viewed by 344 | Submission Open

Keywords: antibiotic resistance; genomic; proteomic; one health

(This special issue belongs to the Section Molecular Biology)

Molecular Markers and Genetic Diversity in Plants

edited by Eugenija Kupčinskienė

submission deadline 30 Nov 2025 | Viewed by 303 | Submission Open

Keywords: plant populations; genetic diversity; molecular diversity; invasion; invasive alien species; pollution; climate change; habitat; conservation; endangered and rare species; DNA markers; molecular markers; sequencing

(This special issue belongs to the Section Molecular Plant Sciences)

Natural Products on Neurological Diseases, Neuroinflammation and Neuropathic Pain

edited by Karin C. Calaza

submission deadline 30 Nov 2025 | Viewed by 279 | Submission Open

Keywords: natural products; neurological diseases; neuroinflammation; neuropathic pain; neuroprotection; anti-inflammatory compounds; pain modulation; plant-based therapies

(This special issue belongs to the Section Bioactives and Nutraceuticals)

New Insights into Intercellular Communication and Signal Transduction

edited by

Dongki Yang

submission deadline 30 Nov 2025 | Viewed by 259 | Submission Open

Keywords: intercellular communication; signal transduction; extracellular vesicles (EVs); exosomes; tunneling nanotubes (TNTs); cytokines; hormonal signaling; neurotransmitters; mechanotransduction; immune signaling

(This special issue belongs to the Section Molecular Biology)

Research Progress on Photosensitizers and Photodynamic Therapy

edited by

Michal Heger

submission deadline 30 Nov 2025 | Viewed by 258 | Submission Open

Keywords: photodynamic therapy; photosensitizers; tumor microenvironment; nanotechnology; immunotherapy; targeted drug delivery; reactive oxygen species; hypoxia; combination therapy; molecular mechanisms

(This special issue belongs to the Section Biochemistry)

Regulation of Brown Adipose Function

edited by

Stephen F. Vatner

and

Shinsuke Nirengi

submission deadline 30 Nov 2025 | Viewed by 253 | Submission Open

Keywords: brown adipose tissue; metabolic disorders; thermogenesis; endocrine function; cellular signaling

(This special issue belongs to the Section Biochemistry)

Recent Research on Glycosylation

edited by

Yang Zhang

submission deadline 30 Nov 2025 | Viewed by 245 | Submission Open

Keywords: protein glycosylation; protein folding; cell signaling; immune regulation; glycoproteins

(This special issue belongs to the Section Biochemistry)

Vitamin D and New Vitamin D Analogs

edited by

Yagamare Fall

submission deadline 30 Nov 2025 | Viewed by 241 | Submission Open

Keywords: vitamin D; vitamin D receptor; vitamin D analogs; synthesis; clinical applications; cancer; anti-proliferation; therapeutic target

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Plant Molecular Ecology and Genomic Perspectives

edited by

Peng Zhao

submission deadline 30 Nov 2025 | Viewed by 231 | Submission Open

Keywords: genome assembly and annotaion; genomic structure and function of plants; plant molecular ecology; genome prediction and GWAS; gene-editing technologies; transcriptomics and metabolomics; nuclear and organelle genomics

(This special issue belongs to the Section Molecular Plant Sciences)

Strategies and Molecular Mechanisms to Enhance Outcomes in Orthobiologics

edited by Leonardo Oliveira

submission deadline 30 Nov 2025 | Viewed by 222 | Submission Open

Keywords: platelet-rich plasma; adipose-derived stem cells; microfragmented fat; nutrition; exercise; biomarkers

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Stem Cell and Epigenetic Regulation in Regenerative Medicine

edited by

Giuseppe Garroni

submission deadline 30 Nov 2025 | Viewed by 219 | Submission Open

Keywords: mesenchymal stem cells; regenerative medicine; stemness genes; stem cell differentiation; molecular regulation; gene expression; cell– environment interactions; conditioned medium; secreted factors; epigenetic modification

(This special issue belongs to the Section Molecular Biology)

Advances in Glyco-Based Anticancer Agents

edited by Pedro Colinas

submission deadline 30 Nov 2025 | Viewed by 216 | Submission Open

Keywords: carbohydrates; cancer; Warburg effect; glycolysis; enzyme inhibitors; transporters inhibitors; docking simulations; tumor microenvironment

(This special issue belongs to the Section Biochemistry)

Lectins: Structural Diversity, Molecular Recognition and Emerging Applications

edited by

Patrícia Maria Guedes Paiva

submission deadline 30 Nov 2025 | Viewed by 215 | Submission Open

Keywords: lectins; structural diversity; molecular recognition; bioactivities; biomedical applications

(This special issue belongs to the Section Biochemistry)

The Application of Biomaterials in Bone Tissue Repair and Regeneration, 2nd Edition

edited by

Jacek Matys

submission deadline 30 Nov 2025 | Viewed by 211 | Submission Open

Keywords: allograft; autograft; autologous bone; bone; graft materials; mineral substitutes; regeneration

(This special issue belongs to the Section Materials Science)

Biomaterials for Bone Treatment, Replacement and Regeneration: Focus on Regeneration and Inflammation

edited by

Mike Barbeck

submission deadline 30 Nov 2025 | Viewed by 210 | Submission Open

Keywords: biomaterials ; bone substitute ; inflammation ; foreign body response ; bone regeneration

(This special issue belongs to the Section Materials Science)

Molecular Design and Engineering of Carbon-Based Materials for Environmental Remediation and Bioenergy

edited by Hilda Elizabeth Reynel-Ávila

submission deadline 30 Nov 2025 | Viewed by 203 | Submission Open

Keywords: adsorption; catalysis; functionalization; molecular design; environmental; sustainable energy; tailoring

(This special issue belongs to the Section Materials Science)

Molecular Research on Ataxia

edited by

Jose Miguel Laffita-Mesa

submission deadline 30 Nov 2025 | Viewed by 203 | Submission Open

Keywords: ataxia; molecular mechanisms; repeat expansion disorders; gene discovery; biomarkers; RNA biology; protein aggregation; epigenetics; gene therapy; neurodegeneration

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Plant Extracts: Molecular Insights and Functional Potential

edited by Abdelaziz Yasri

submission deadline 30 Nov 2025 | Viewed by 200 | Submission Open

Keywords: plant extract; phytochemistry; plant secondary metabolites; plant extraction techniques; product valorization

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Advances in Pediatric Neuromuscular Disorders

edited by

Tai-Heng Chen

submission deadline 30 Nov 2025 | Viewed by 200 | Submission Open

Keywords: pediatric neuromuscular disorders; gene therapy; biomarkers; molecular pathophysiology; muscular dystrophy; motor neuron disease; translational medicine; neuromuscular therapies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Sustainable Material Development Through Waste Utilization: From Molecular Insights to Functional Applications

edited by

Rosie Yagmur Yegin

submission deadline 30 Nov 2025 | Viewed by 199 | Submission Open

Keywords: sustainable materials; waste-derived materials; biodegradable polymers; green chemistry; functionalization; structure– property relationships; chemical modification; recycling; valorization; circular economy; composites; analytical techniques; industrial waste; agricultural waste

(This special issue belongs to the Section Materials Science)

Displaying special issue 351-400 on page 8 of 69.

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