Histamine Receptors: Biology, Pharmacology, and Therapeutic Potential
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 31 August 2026 | Viewed by 143
Special Issue Editor
Interests: histamine receptor agonists; transgenic animals; heart failure; arrhythmias
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Histamine is a well-studied compound that is found in the mammalian organs but can also enter the body via food. Histamine acts via at least four different receptors, each with different signal transduction pathways. Some histamine receptors may use more than pathway. The expression and function of histamine receptors are age-, disease-, and species-dependent. Some patients have mutated histamine receptors, which can alter the function of histamine and contribute to disease. Many drugs selectively block some histamine receptors, while fewer drugs are known to stimulate histamine receptors. The main organs where histamine receptors play a role are the intestine, the immune system, and the nervous system. However, cardiac histamine receptors are also of relevance. In this Special Issue, we wish to provide the opportunity to present new findings on the role of histamine and histamine receptors in the form of reviews and original biochemical studies. Special emphasis should be placed on new drugs and mechanisms in the field. We welcome a wide array of clinical subjects that cast new light on the relevance of histamine receptors.
Prof. Dr. Joachim Neumann
Guest Editor
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Keywords
- histamine
- histamine receptor agonist
- histamine receptor antagonist
- signal transduction
- polymorphisms
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