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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Aspects of Diabetes and Its Complications

edited by

Giuseppe Murdolo

submission deadline 20 Aug 2026 | Viewed by 207 | Submission Open

Keywords: obesity; insulin resistance; type 2 diabetes; atherosclerosis; endothelial dysfunction; cardiovascular disease; peripheral artery disease; diabetic feet; diabetic micoangiopathy; diabetic neuropathy; regenerative medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Lipopolysaccharide as a Drug Target

edited by

Martina Schmidt

submission deadline 20 Aug 2026 | Viewed by 154 | Submission Open

Keywords: tissue barriers; neuroinflammation; macrophages; microglia; organoids; scaffolds; infections; cry-EM

(This special issue belongs to the Section Molecular Pharmacology)

Vitamin D in Reproductive Disorders: Determinants, Metabolism, and Downstream Biological Mechanisms

edited by

Eugenia Mata-Greenwood

submission deadline 20 Aug 2026 | Viewed by 94 | Submission Open

Keywords: vitamin D; perinatal corticosteroids; placental insufficiency; intrauterine growth restriction; cortisol metabolism

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Effects of Radiation in Health and Disease

edited by

Raffaella Lazzarini

submission deadline 20 Aug 2026 | Viewed by 35 | Submission Open

Keywords: extremely low-frequency magnetic fields; proteins and gene interaction; ionizing and non-ionizing radiations

(This special issue belongs to the Section Molecular Biology)

Current Research on Lipidomics

edited by Agata Kot-Wasik

submission deadline 25 Aug 2026 | Viewed by 36 | Submission Open

Keywords: lipids ; hyphenated chromatography– mass spectrometry ; biological samples ; sample preparation

(This special issue belongs to the Section Molecular Biology)

Natural Compounds in Cancer Treatment and Prevention: Mechanisms, Evidence, and Clinical Perspectives

edited by Vitor Engracia Valenti

submission deadline 25 Aug 2026 | Viewed by 31 | Submission Open

Keywords: natural compounds; cancer treatment; cancer prevention; bioactive phytochemicals

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Neurotransmitter Dysregulation in Brain Disease: Focus on Epilepsy and Its Comorbidities

edited by

Giuseppe Di Giovanni

submission deadline 30 Aug 2026 | Viewed by 116 | Submission Open

Keywords: neurotransmitter dysregulation; epilepsy; addiction; serotonin; GABA; molecular neuroscience; neuropharmacology; brain networks

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Mechanisms Fueling Glioblastoma Progression and Resistance: Emerging Therapeutic Opportunities

edited by

Anthony Lemarié

submission deadline 30 Aug 2026 | Viewed by 75 | Submission Open

Keywords: glioblastoma; cancer stem cells; radioresistance; chemoresistance; targeted therapies; tumor plasticity; tumor heterogeneity; invasion; immune escape

(This special issue belongs to the Section Molecular Neurobiology)

MiRNA Regulation in the Early PME/TME: The Role of Non-Cancer Cells and the ECM in Solid Tumours

edited by

Kurt Sartorius

submission deadline 30 Aug 2026 | Viewed by 59 | Submission Open

Keywords: microRNAs; early tumor microenvironment (TME); stromal/ECM interaction; vascularization; ECM remodelling; signalling pathways

(This special issue belongs to the Section Molecular Oncology)

Evolutionary Genetics of Pathogens

edited by Leonardo Gabriel Panunzi

submission deadline 30 Aug 2026 | Viewed by 31 | Submission Open

Keywords: pathogenicity; genome evolution; horizontal gene transfer; virulence factors; comparative genomics; pangenome analysis mobile genetic elements; computational biology; machine learning; host– pathogen interactions

(This special issue belongs to the Section Molecular Genetics and Genomics)

Latest Advances in Antiparasitic Agents

edited by Olga S. Koutsoni and

Maria Agallou

submission deadline 30 Aug 2026 | Viewed by 27 | Submission Open

Keywords: parasite genomics; parasite proteomics; metabolic pathways; parasite– host interactions; drug targets; mechanisms of drug resistance

(This special issue belongs to the Section Molecular Pharmacology)

Cardioprotective Mechanisms in Myocardial Ischemia

edited by Virginia Pérez and Verónica D’annunzio

submission deadline 30 Aug 2026 | Viewed by 25 | Submission Open

Keywords: myocardial ischemia; ischemia– reperfusion injury; cardioprotection; molecular signaling; oxidative stress; inflammation; cardiac remodeling; therapeutic targets; translational cardiology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Biomarkers and Early Detection Strategies of Ovarian Tumors: 2nd Edition

edited by Lukasz Szafron

submission deadline 30 Aug 2026 | Viewed by 16 | Submission Open

Keywords: biomarker; ovarian cancer; borderline ovarian tumor; genetic variant; epigenetics; transciptomics; proteomics; metabolomics; ovarian tumor prevention; ovarian tumor treatment

(This special issue belongs to the Section Molecular Oncology)

The Role of Neuropeptides and Their GPCRs in the Neuroendocrine System

edited by

Hirotaka Sakamoto

submission deadline 31 Aug 2026 | Viewed by 567 | Submission Open

Keywords: neuropeptides; G-protein-coupled receptors (GPCRs); neuroendocrine system; signal transduction; hypothalamus

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Neuropathology of Alzheimer’s Disease: Tau, Amyloid-β, and Novel Protein Associations

edited by

José Luna-Muñoz

and Alejandra Morlett-Paredes

submission deadline 31 Aug 2026 | Viewed by 93 | Submission Open

Keywords: tauopathies and protein aggregation; amyloid beta and neurotoxicity; emerging proteins in neurodegeneration; molecular and morphological biomarkers; innovative therapies and experimental targets; artificial intelligence and neuropathological analysis

(This special issue belongs to the Section Molecular Neurobiology)

Advances in Alzheimer's Disease and Related Dementias: From Pathogenesis to Therapeutics

edited by

Amal Kaddoumi

submission deadline 31 Aug 2026 | Viewed by 36 | Submission Open

Keywords: Alzheimer's disease; cerebral amyloid angiopathy; blood– brain barrier; cerebrovascular dysfunction; neuroinflammation; therapeutic development; translational research

(This special issue belongs to the Section Molecular Neurobiology)

Animal Models for Neurobiological Diseases

edited by

Hiroki Toyoda

and

Jana Tchekalarova

submission deadline 31 Aug 2026 | Viewed by 35 | Submission Open

Keywords: animal models; mice; zebrafish; Alzheimer's disease; Parkinson's disease; multiple sclerosis; neuropsychiatric conditions

(This special issue belongs to the Section Molecular Neurobiology)

Lipid Metabolism in Aging and Diseases: From Mechanisms to Therapy

edited by

Dominique Delmas

submission deadline 31 Aug 2026 | Viewed by 23 | Submission Open

Keywords: lipid metabolism; degenerative diseases; cardiovascular pathologies; neurodegeneration; inflammation; autoimmunity; cancer; lipid droplets; bioactive molecules; drug repositioning; oxidative stress; mitochondrial dysfunction; inflammatory processes

(This special issue belongs to the Section Biochemistry)

Molecular and Nanostructured Materials for Energy, Environmental, and Biomedical Applications

edited by

Balaji Murugan

submission deadline 31 Aug 2026 | Viewed by 20 | Submission Open

Keywords: advanced sustainable materials; molecular engineering; energy conversion and storage (supercapacitor; solar cells; and batteries); electrocatalysis and photocatalysis; environmental remediation; biomedical applications; bio/electrochemical sensing and bioelectronics; molecular surface structure and interface chemistry; in situ/operando spectroscopy

(This special issue belongs to the Section Molecular Nanoscience)

Molecular Mechanisms in Cardiovascular and Metabolic Diseases: Effective and Potential Treatments

edited by

Alex Cleber Improta-Caria

submission deadline 31 Aug 2026 | Viewed by 4 | Submission Open

Keywords: molecular mechanisms; cardiovascular diseases; metabolic diseases; microRNAs; circRNAs; long non-coding RNAs; epigenetics

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advanced Research in Veterinary Drugs

edited by Jianyong Li

submission deadline 20 Sep 2026 | 1 articles | Viewed by 1705 | Submission Open

Keywords: veterinary drug; target; chemical structure; mechanism; medicinal chemistry; toxicity; pharmacodynamics; pharmacokinetics; residues

(This special issue belongs to the Section Molecular Pharmacology)

Advanced Composite Materials: Molecular Design and Applications

edited by Fan Yang

submission deadline 20 Sep 2026 | Viewed by 232 | Submission Open

Keywords: multifunctional applications; mechanical and physical properties; extreme environments; molecular dynamics analysis; composite molecular design; preparation; simulation; and characterization

(This special issue belongs to the Section Materials Science)

Exopolysaccharides of Microbial Origin: Production, Analysis and Modification

edited by Marzena Jedrzejczak-Krzepkowska and

Karolina Ludwicka

submission deadline 20 Sep 2026 | Viewed by 80 | Submission Open

Keywords: exopolysaccharide; biopolymer; biofilm; microorganism; biosynthesis; genetic engineering; molecular design; modification; analysis

(This special issue belongs to the Section Molecular Microbiology)

Molecular Research on Tea Flavor and Chemistry

edited by

Wei Xu

submission deadline 29 Sep 2026 | Viewed by 97 | Submission Open

Keywords: tea processing; tea chemistry; tea functional components; tea sensory evaluation; tea quality control

(This special issue belongs to the Section Biochemistry)

Molecular Mechanisms in Forensic Pathology

edited by

Vittorio Fineschi

submission deadline 29 Sep 2026 | Viewed by 52 | Submission Open

Keywords: molecular investigation; molecular thanatocronology; molecular autopsy; lesion vitality; molecu-lar forensic toxicology; pharmacogenomics; molecular identification

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Plant Transporters and Tolerance Proteins

edited by Kun Qiao

submission deadline 29 Sep 2026 | Viewed by 15 | Submission Open

Keywords: heavy metal; transporter; antioxidant; ornamental plants and horticulture; ion transport; phytoremediation; biofortification

(This special issue belongs to the Section Molecular Plant Sciences)

Common Mechanisms in Gestational Diabetes, Preeclampsia, and Coronavirus Disease 2019

edited by

Sandor G. Vari

submission deadline 30 Sep 2026 | 7 articles | Viewed by 9795 | Submission Open

Keywords: gestational diabetes; preeclampsia; inflammation; immunoglobulins; glycolisation; platelet aggregation; microvascular thrombosis; coronavirus disease 2019

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Genetic, Functional and Therapeutic Aspects of Procoagulant and Anticoagulant Factors (Third Edition)

edited by

Rima Dardik

and

Tami Livnat

submission deadline 30 Sep 2026 | 1 articles | Viewed by 839 | Submission Open

Keywords: procoagulant factors; anticoagulant factors; hemostasis; inflammation; genetics; therapeutics; cell signaling

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Phytochemical Insights and Green Extraction Strategies for Bioactive Natural Compounds

edited by

Ana M. L. Seca

and

Gonçalo Pereira da Rosa

submission deadline 30 Sep 2026 | Viewed by 167 | Submission Open

Keywords: plant and algal bioactive metabolites; phytochemistry; green extraction techniques; natural sustainable solvents (NADES); structural elucidation of natural molecules; molecular characterization

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Mechanism, Pathogenesis, and Precision Therapeutics in Thyroid Cancer

edited by

Laura Sterian Ward

submission deadline 30 Sep 2026 | Viewed by 81 | Submission Open

Keywords: thyroid cancer; molecular pathogenesis; driver mutations; tumor microenvironment; targeted therapy; resistance mechanisms; immunotherapy; precision oncology; liquid biopsy; prognostic biomarkers

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Protein Dynamics in Cancer Drug Resistance: Mechanisms and Therapeutic Opportunities

edited by Slovénie Pyndiah

submission deadline 30 Sep 2026 | Viewed by 33 | Submission Open

Keywords: drug resistance; cancer proteome; protein turnover; post-translational modifications; targeted therapy; stress adaptation

(This special issue belongs to the Section Molecular Oncology)

Molecular Advances of Gut–Brain Communications

edited by

Walter Pirovano

submission deadline 30 Sep 2026 | Viewed by 18 | Submission Open

Keywords: gut-brain axis; microbiome; molecular profiling; omics/multi-omics data; functional measurements; analytical methods; computational methods; neurological disorders; neuropsychiatric disorders

(This special issue belongs to the Section Molecular Biology)

Natural Products in Drug Discovery and Development: 2nd Edition

edited by Tian-Le Gao

submission deadline 30 Sep 2026 | Submission Open

Keywords: natural product components; traditional medicine; biological entropy reduction; aromatic drugs; essential oils; gut microbiota modulation; probiotics; drug discovery

(This special issue belongs to the Section Molecular Pharmacology)

Procoagulant Platelets in Vascular Disease and Beyond

edited by

Paresh P. Kulkarni

submission deadline 30 Sep 2026 | Submission Open

Keywords: procoagulant platelets; thrombosis; hemostasis; coagulation; bleeding; vascular disease; cancer; cardiometabolic syndrome; inflammation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Circumventing Resistance to Channel-Targeting Insecticides: A Challenge for Global Health and Food Security

edited by

Bruno Lapied

and David Barry Sattelle

submission deadline 20 Oct 2026 | 1 articles | Viewed by 633 | Submission Open

Keywords: pest insects and resistance; resistance in insect vectors of human and livestock diseases; mechanisms of resistance; circumventing resistance; ion channels and resistance; integrated approaches to resistance management; alternating insecticide classes; minimizing risk to beneficial insects; novel control strategies

(This special issue belongs to the Section Molecular Biology)

Advance in Plant Abiotic Stress: 4th Edition

edited by

De-Guo Han

and

Xingguo Li

submission deadline 30 Oct 2026 | 1 articles | Viewed by 587 | Submission Open

Keywords: abiotic stress; cold; drought; salt; heat; nutrient deficiency; secondary metabolism; stress resistance; plant

(This special issue belongs to the Section Molecular Plant Sciences)

Precision Photosynthesis: Mechanisms and Applications in Controlled Environments

edited by

Jiangtao Hu

submission deadline 30 Oct 2026 | Viewed by 61 | Submission Open

Keywords: controlled environment agriculture (CEA); photobioreactor; plant growth chamber; light-emitting diode (LED) spectrum; photosynthetic efficiency; acclimation; synthetic biology; metabolic engineering; high-throughput phenotyping; predictive modeling; vertical farming

(This special issue belongs to the Section Molecular Plant Sciences)

Nanostructured Materials and Functional Molecules for Sustainable Applications

edited by

Giulia Rando

Maria Rosaria Plutino

and

Silvia Sfameni

submission deadline 30 Oct 2026 | Viewed by 28 | Submission Open

Keywords: nanostructured materials; functional molecules; molecular design; sustainable materials; carbon nanotubes (CNTs); biochar; nanocomposites; nanohybrids; surface functionalization; molecular interactions; green synthesis; advanced functional materials

(This special issue belongs to the Section Materials Science)

The Mechanisms of Cucurbit Breeding, Cultivation and Quality Regulation

edited by Yongxue Zhang and Xiaotao Ding

submission deadline 30 Oct 2026 | Viewed by 22 | Submission Open

Keywords: omics; cultivation; breeding; quality; abiotic stress tolerance

(This special issue belongs to the Section Molecular Plant Sciences)

Organ Axis: Insights from Molecular Metabolism

edited by

Peiwen Wang

submission deadline 31 Oct 2026 | Viewed by 35 | Submission Open

Keywords: organ axis; molecular metabolism; interorgan crosstalk; metabolic regulation; metabolic diseases; biomarkers; molecular pathways; metabolites

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Cotton Breeding and Genetics: Advances and Perspectives

edited by Xuwu Sun

submission deadline 31 Oct 2026 | Viewed by 28 | Submission Open

Keywords: molecular design breeding; smart breeding; CRISPR-Cas; artificial intelligence; cotton genomics; multi-omics; high-throughput phenotyping; trait prediction; genome editing; crop improvement

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Mechanisms and Emerging Therapies in Neurovascular Disease

edited by Leonidas D. Panos

submission deadline 20 Nov 2026 | 3 articles | Viewed by 12537 | Submission Open

Keywords: neurovascular diseases; blood– brain barrier; endothelial dysfunction; cellular signaling; gene therapy

(This special issue belongs to the Section Molecular Neurobiology)

Advancing Precision Medicine in Urological Cancers: Integrating Multi-Omics and Optimizing Therapeutic Approaches

edited by Magaly Martinez-Ferrer

submission deadline 20 Nov 2026 | 1 articles | Viewed by 3766 | Submission Open

Keywords: prostate cancer; proteomics; metabolomics; precision medicine; biomarker

(This special issue belongs to the Section Molecular Oncology)

Biomolecular Condensates and Their Role in Cellular Organization and Disease

edited by Anna Bratek-Skicki

submission deadline 20 Nov 2026 | Viewed by 633 | Submission Open

Keywords: biocondensates; membrane-less organelles; liquid-liquid phase separation; protein aggregation; neurogenerative diseases

(This special issue belongs to the Section Molecular Biology)

Bioactives in Processed Foods: Profiling and Bioavailability Assessment

edited by Cong Wang

submission deadline 20 Nov 2026 | Viewed by 259 | Submission Open

Keywords: food processing; food bioactives; composition; bioavailability; functionality; novel food processing techniques; structure/constituents– bioactivity relationship

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Advances in Molecular Research on Cancer Treatments: Apoptosis, Autophagy, and Drug Selection

edited by

Md Ataur Rahman

submission deadline 20 Dec 2026 | 4 articles | Viewed by 12384 | Submission Open

Keywords: autophagy; apoptosis; bioactive natural products; nanoparticles and drug delivery; cancer immunotherapy; in silico and network pharmacology; bioinformatics

(This special issue belongs to the Section Molecular Oncology)

Research in Alzheimer’s Disease: Advances and Perspectives

edited by

Silvia Boschi

submission deadline 20 Dec 2026 | 3 articles | Viewed by 3468 | Submission Open

Keywords: neuroinflammation; synaptic dysfunction; oxidative stress; neurofibrillary tangles; mitochondrial dysfunction; biomarkers

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Stem Cell Innovations and Reproductive Biotechnologies

edited by

Marcin Samiec

submission deadline 30 Dec 2026 | Viewed by 621 | Submission Open

Keywords: mammals; birds; stem cell research; pluri-/multipotency; differentiation/dedifferentiation; assisted reproductive technologies (ARTs); transgenic research; biomedicine

(This special issue belongs to the Section Molecular Biology)

Research Progress on Disease Models Based on Induced Pluripotent Stem Cells

edited by

Delger Bayarsaikhan

submission deadline 30 Dec 2026 | Viewed by 74 | Submission Open

Keywords: induced pluripotent stem cells; iPSC-derived cells; disease modeling; precision and regenerative medicine; genome editing; CRISP/Cas; organoid; cell sheet; personalized therapeutics; drug discovery

(This special issue belongs to the Section Molecular Biology)

Displaying special issue 3101-3150 on page 63 of 63.

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