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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Bio-Based Corrosion Inhibitors: Approaches and Mechanisms

edited by Laila Afia

submission deadline 31 Mar 2027 | Viewed by 3 | Submission Open

Keywords: green corrosion inhibitors; phytochemical adsorption; scanning electron microscopy (SEM); X-ray photoelectron spectroscopy (XPS); electrochemical impedance spectroscopy (EIS); density functional theory (DFT); molecular dynamics (MD)

(This special issue belongs to the Section Materials Science)

Molecular Regulation of Angiogenesis and Vascular Remodeling: Mechanisms and Therapeutic Targets

edited by

Geetika Kaur

submission deadline 31 Mar 2027 | Viewed by 1 | Submission Open

Keywords: angiogenesis; endothelial cell; vascular development; molecular pathways; VEGF/VEGFR signaling; endothelial crosstalk; vascular network

(This special issue belongs to the Section Molecular Biology)

Omics and Network Pharmacology in Phytomedicine and Disease Therapeutics

edited by

Pandiyan Muthuramalingam

submission deadline 31 Mar 2027 | Submission Open

Keywords: AI-ML; computational biology; drug discovery; enrichment analyses; medicinal plants; network pharmacology; omics; traditional medicine

(This special issue belongs to the Section Molecular Pharmacology)

Probiotic Bioactives: Molecular Mechanisms and Applications

edited by

Houssam Abouloifa

and

Nabil Ghabbour

submission deadline 31 Mar 2027 | Submission Open

Keywords: probiotics; postbiotics; bioactive compounds; bio-preservation; health benefits; lactic acid bacteria; antibacterial; antifungal; functional properties

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Microbial Modulation in Human Immune and Metabolic Systems: Emerging Mechanisms and Translational Opportunities

edited by

Hooi-Leng Ser

submission deadline 1 Apr 2027 | Viewed by 169 | Submission Open

Keywords: host–microbe interactions; immune regulation; metabolic homeostasis; microbial metabolites; dysbiosis; microbiome interventions; translational microbiology

(This special issue belongs to the Section Molecular Microbiology)

Biomaterials for Dental and Orthopedic Applications, 2nd Edition

edited by

Lia Rimondini

submission deadline 20 Apr 2027 | 1 articles | Viewed by 977 | Submission Open

Keywords: personalized biomaterials; dental and orthopedic applications; tissue regeneration; 3D biorinting

(This special issue belongs to the Section Materials Science)

Integrative Multi-Omics in Neurodegenerative Diseases: Mechanisms, Biomarkers and Therapeutic Targets

edited by

Abdullah Sheikh

submission deadline 20 Apr 2027 | Submission Open

Keywords: multi-omics; neurodegenerative diseases; systems biology; biomarkers; precision medicine; transcriptomics; proteomics; metabolomics; epigenomics

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Cellular and Molecular Mechanisms in the Progression of Cardiovascular Diseases

edited by

Eglė Mazgelytė

submission deadline 22 Apr 2027 | Viewed by 45 | Submission Open

Keywords: cardiovascular diseases; molecular mechanisms; cellular signaling; inflammation; oxidative stress; cardiac remodeling; endothelial dysfunction; biomarkers; precision medicine; translational cardiovascular research

(This special issue belongs to the Section Molecular Biology)

Neurodegenerative Diseases: Molecular Mechanisms and Therapies, 4th Edition

edited by

Zhidong Zhou

and

Alexandre Hiroaki Kihara

submission deadline 23 Apr 2027 | 1 articles | Viewed by 1239 | Submission Open

Keywords: neurodegeneration; neurodegenerative diseases; protein aggregation; pathogenesis; therapy; mitochondria; neuroinflammation; oxidative stress; cell therapy; clinical trial

(This special issue belongs to the Section Molecular Neurobiology)

Advances in Molecular Biology of Haematology

edited by Valéria Tavares

submission deadline 23 Apr 2027 | 1 articles | Viewed by 796 | Submission Open

Keywords: haematopoiesis; molecular biology; genomics; epigenomics; computational biology; hematologic neoplasms; biomarkers; liquid biopsy; precision medicine

(This special issue belongs to the Section Molecular Biology)

Molecular Mechanisms of Innate Immunity and Disease Resistance in Animals

edited by

Sutian Wang

submission deadline 23 Apr 2027 | Viewed by 442 | Submission Open

Keywords: innate immunity; pathogenic microorganism; animals; pathogenesis; mechanism of disease-resistance; disease-resistant/therapeutic target

(This special issue belongs to the Section Molecular Immunology)

New Approaches in Molecular and Cellular Cancer Biology: Translating Basic Research to the Clinic

edited by

Rafael Coveñas Rodríguez

and

Maruan Hijazi Vega

submission deadline 29 Apr 2027 | Viewed by 56 | Submission Open

Keywords: cell signaling; proteomics; phosphoproteomics; mass spectrometry; kinase inhibitors; kinase activity; signaling networks; computational biology; peptide receptor antagonists; anticancer and cancer peptides

(This special issue belongs to the Section Molecular Oncology)

Male Infertility: Emerging Trends and Future Directions

edited by

Monica Muratori

and

Oumaima Ammar

submission deadline 29 Apr 2027 | Viewed by 43 | Submission Open

Keywords: male infertility; epigenetics; multi-omics; spermatogenesis; assisted reproduction; phytotherapy; artificial intelligence

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Inflammasomes

edited by

Roberto Negro

submission deadline 30 Apr 2027 | 3 articles | Viewed by 4015 | Submission Open

Keywords: inflammasome; pyroptosis; innate immunity; cancer; neurodegenerative diseases; microbiota; gasdermin; ninjurin; drug screening; personalized treatments; multi-omics analysis

(This special issue belongs to the Section Molecular Immunology)

Molecular Mechanisms of Toxicity Caused by Environmental Pollutants

edited by Ivan Girón-Perez

submission deadline 30 Apr 2027 | 4 articles | Viewed by 2716 | Submission Open

Keywords: environmental pollutant; molecular toxicity; immunotoxicology; neurotoxicity

(This special issue belongs to the Section Molecular Toxicology)

Protein–Protein Interactions in Human Cancer

edited by

Geng Wu

submission deadline 30 Apr 2027 | 2 articles | Viewed by 2340 | Submission Open

Keywords: protein–protein interactions; protein–protein complexes; human cancer; signal transduction pathways; protein structure and function

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Insights in Multiple Sclerosis (MS) and Neuroimmunology: 3rd Edition

edited by

Michael C. Levin

submission deadline 30 Apr 2027 | 2 articles | Viewed by 2014 | Submission Open

Keywords: neurodegeneration; neuroimmunology; macrophage; T-cell; B-cell; antibody; neurons; oligodendrocytes; axon; axonal damage; cell death; multiple sclerosis

(This special issue belongs to the Section Molecular Immunology)

Advances in Alzheimer's Disease and Related Dementias: From Pathogenesis to Therapeutics

edited by

Amal Kaddoumi

submission deadline 30 Apr 2027 | 1 articles | Viewed by 1118 | Submission Open

Keywords: Alzheimer's disease; cerebral amyloid angiopathy; blood–brain barrier; cerebrovascular dysfunction; neuroinflammation; therapeutic development; translational research

(This special issue belongs to the Section Molecular Neurobiology)

Lipid Metabolic and Signaling Dysregulations: From Molecular Mechanisms to Disease Pathogenesis

edited by Gergana M. Deevska

submission deadline 30 Apr 2027 | 2 articles | Viewed by 1044 | Submission Open

Keywords: lipid signaling; lipid metabolism; lipid homeostasis; metabolic dysregulation; signal transduction; disease pathogenesis

(This special issue belongs to the Section Molecular Biology)

New Research on Toxicology Research Models

edited by

Cláudia Maria Rosa Ribeiro

and

María Carolina Rocha-Pereira

submission deadline 30 Apr 2027 | 1 articles | Viewed by 981 | Submission Open

Keywords: contaminants of emerging concern; aquatic organisms; in vitro; in vivo; mammalian approaches; mechanisms of toxicity; environmental risk assessment; one health

(This special issue belongs to the Section Molecular Toxicology)

New Insights into Gastroesophageal Tumors

edited by

Michela Guardascione

and Luisa Foltran

submission deadline 30 Apr 2027 | 2 articles | Viewed by 885 | Submission Open

Keywords: gastric cancer; esophageal cancer; biomarkers; target therapy; immunotherapy; NGS

(This special issue belongs to the Section Molecular Oncology)

Probiotics, Prebiotics, Synbiotics, and Gut Microbial Modulation in Intestinal Health and Disease

edited by Koji Yamamoto

submission deadline 30 Apr 2027 | 1 articles | Viewed by 721 | Submission Open

Keywords: gut microbiota; probiotics; prebiotics; synbiotics; inter-organ network; intestinal barrier; microbial metabolites; immunoregulation; multi-omics; inflammatory bowel disease; microbiome-based therapy

(This special issue belongs to the Section Molecular Microbiology)

Phytohormones in Plant Responses to Abiotic Stress

edited by

Marzena Kurowska

submission deadline 30 Apr 2027 | 1 articles | Viewed by 689 | Submission Open

Keywords: phytohormones; hormone signaling; abiotic stress responses; signaling crosstalk; transcriptional regulation; gene expression; molecular mechanisms

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Nutrition and Food Science

edited by

Sze Ying Leong

and

Indrawati Oey

submission deadline 30 Apr 2027 | 1 articles | Viewed by 590 | Submission Open

Keywords: molecular nutrition; functional foods; bioactives; food matrix; nutrient bioavailability; digestion kinetics; gut microbiota; nutritional functionality; food structure–function relationships; food reformulation; food science

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Advances in Plant Transporters and Tolerance Proteins

edited by Kun Qiao

submission deadline 30 Apr 2027 | Viewed by 262 | Submission Open

Keywords: heavy metal; transporter; antioxidant; ornamental plants and horticulture; ion transport; phytoremediation; biofortification

(This special issue belongs to the Section Molecular Plant Sciences)

Forward in Vasculitis: Genetics and Beyond, 2nd Edition

edited by

Marija Jelusic

submission deadline 30 Apr 2027 | Viewed by 229 | Submission Open

Keywords: systemic vasculitides; ethiopathogenesis; risk factors; genetics; genomics; proteomics; transcriptomics; epigenetics; molecular pathways; novel therapeutic strategies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Targeting Membrane Proteins: Structure, Function, and Dynamic Relationships

edited by Ki-Young Lee

submission deadline 30 Apr 2027 | Viewed by 96 | Submission Open

Keywords: membrane proteins; conformational dynamics; allosteric regulation; signal transduction; drug discovery; cryo-electron microscopy; nuclear magnetic resonance spectroscopy; artificial intelligence; membrane mimetics

(This special issue belongs to the Section Molecular Biology)

Biochemical Mechanisms of the Gut–Brain Axis: Microbial Metabolites, Barrier Integrity, and Neuroimmune Signaling

edited by

Sidharth Prasad Mishra

submission deadline 30 Apr 2027 | Viewed by 92 | Submission Open

Keywords: gut–brain axis; gut microbiota; microbial metabolites; intestinal barrier integrity; neuroimmune signaling; host-microbiome interactions; microbiome-brain communication; neuroinflammation; multi-omics; microbiome-based therapeutics

(This special issue belongs to the Section Molecular Biology)

Molecular Evolution of the Vertebrate Immune System

edited by

Pierre Pontarotti

submission deadline 30 May 2027 | 1 articles | Viewed by 1297 | Submission Open

Keywords: immune system; molecular evolution; V (D) J recombination; RAG transposon; comparative genomics

(This special issue belongs to the Section Molecular Biology)

Molecular Biology on Environmental Microorganisms

edited by

Mariusz Cycoń

submission deadline 31 May 2027 | 3 articles | Viewed by 1599 | Submission Open

Keywords: environmental microbiology; metagenomics; microbial interactions; phage–host dynamics; horizontal gene transfer; biogeochemical cycles; antimicrobial resistance; single-cell methods; microbiome engineering; environmental biotechnology

(This special issue belongs to the Section Molecular Microbiology)

Advanced Drug Delivery Systems: From Nanocarrier Design to Translation

edited by

Krishna Jadhav

and

Satish Rojekar

submission deadline 31 May 2027 | Viewed by 104 | Submission Open

Keywords: nanocarriers; stimuli-responsive; targeted delivery; biocompatibility; scale-up; nanomedicine

(This special issue belongs to the Section Materials Science)

Molecular Mechanisms Linking Environmental Pollutant Exposure to Human Health and Development

edited by Agnieszka Ścibior and

Juan Llopis

submission deadline 31 May 2027 | Viewed by 71 | Submission Open

Keywords: environmental pollutants; molecular toxicology; developmental toxicology; particulate matter; metals and metalloids; pesticides; persistent organic pollutants; PFAS; environmental pharmaceuticals; microplastics; nanoplastics; mixture toxicity; adverse outcome pathways; human biomonitoring; toxicokinetics; oxidative stress; genotoxicity; epigenetics; endocrine disruption; neurodevelopment; human health risk assessment

(This special issue belongs to the Section Molecular Toxicology)

Functional Polymeric Biomaterials: From Molecular Engineering to Biomedical Applications

edited by

Joanna Rydz

Marta Musioł

, Khadar Duale and

Barbara Zawidlak-Węgrzyńska

submission deadline 1 Jun 2027 | Viewed by 33 | Submission Open

Keywords: polymeric biomaterials; biodegradable polymers; molecular design; AI-driven materials design; structure–property relationships; biomolecule–material interactions; biocompatibility; drug delivery systems; tissue engineering; regenerative medicine

(This special issue belongs to the Section Materials Science)

The Chitosan Biomaterials: Advances and Challenges, 3rd Edition

edited by

Lacramioara Popa

Mihaela Violeta Ghica

and Cristina Elena Dinu-Pirvu

submission deadline 20 Jun 2027 | 1 articles | Viewed by 1586 | Submission Open

Keywords: chitosan; chitosan biomaterials; chitosan derivatives; drug delivery; wound healing; tissue regeneration; dentistry; smart biomaterials

(This special issue belongs to the Section Materials Science)

Molecular Progression of Genome-Related Diseases: 2nd Edition

edited by

Salvatore Saccone

submission deadline 25 Jun 2027 | 6 articles | Viewed by 21909 | Submission Open

Keywords: next-generation sequencing; genetic diseases; multifactorial diseases; diagnostic tolls; human health

(This special issue belongs to the Section Molecular Genetics and Genomics)

Effects of Bioactive Compounds in Cardiovascular and Neurological Diseases

edited by

Paul-Mihai Boarescu

submission deadline 30 Jun 2027 | 1 articles | Viewed by 2715 | Submission Open

Keywords: inflammation; oxidative stress; bioactive compounds; cardiovascular diseases; neurological diseases

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Targeting Oxidative Stress: New Insights into Disease Pathogenesis, Emerging Preventive Strategies and Novel Therapeutic Approaches

edited by Fabio Vivarelli and

Donatella Canistro

submission deadline 30 Jun 2027 | 2 articles | Viewed by 1879 | Submission Open

Keywords: metabolism; inflammation; oxidative stress; diabetes; natural oxidative stress modulators; novel preventive/therapeutic strategies; ageing; cardiovascular diseases; regenerative medicine; neurodegeneration; environmental exposure; cancer

(This special issue belongs to the Section Molecular Biology)

From Molecular Understanding to Ecological Significance: Understanding Marine Reproductive Biology

edited by

Zohaib Noor

submission deadline 30 Jun 2027 | Viewed by 424 | Submission Open

Keywords: reproductive biology; gametogenesis; bivalves reproduction; biodiversity; endocrine regulation; gametogenesis; molecular signaling; genomics; fertilization; population dynamics; ecological resilience

(This special issue belongs to the Section Molecular Biology)

Sex and Gender Medicine: New Horizons in Human Health and Disease

edited by

Alessandra Carè

, Eliana Ferroni and

Elena Ortona

submission deadline 30 Jun 2027 | Viewed by 125 | Submission Open

Keywords: sex differences; gender medicine; personalized medicine; health inequities; intersectionality; precision health

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Nanoparticle Toxicity: Beyond Chemical Composition—the Critical Role of Physicochemical Properties

edited by

Karen Khachatryan

submission deadline 31 Jul 2027 | 1 articles | Viewed by 1182 | Submission Open

Keywords: nanotoxicology; engineered nanomaterials; physicochemical properties; risk assessment; reactive oxygen species (ROS); protein corona; cellular uptake; regulatory science; safe-by-design

(This special issue belongs to the Section Molecular Toxicology)

Selected Papers from the HSG-2025 Conference

edited by

Marsel Kabilov

submission deadline 31 Jul 2027 | 1 articles | Viewed by 832 | Submission Open

Keywords: metagenomics; genomics; metabarcoding; next-generation sequencing; transcriptomics; translatomics; NGS data analysis

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Research on Aging: Genetics, Epigenetics and Biomolecular Interventions

edited by

Shin Murakami

submission deadline 31 Jul 2027 | Viewed by 10 | Submission Open

Keywords: aging; biomarkers; bioactive nutrients; centenarians; life-extending interventions; exercise; red wine; stress resistance and metabolism; age-related diseases

(This special issue belongs to the Section Molecular Biology)

Molecular Mechanisms, Biomarkers, and Translational Research in Stroke and Neurotrauma

edited by Kang-Ho Choi

submission deadline 30 Aug 2027 | Submission Open

Keywords: stroke; cerebrovascular disease; endovascular thrombectomy; prognostic biomarkers; molecular pathophysiology; neurovascular imaging; lipidomic metabolites; experimental neurology; clinical trial methodologies; novel therapeutic approaches

(This special issue belongs to the Section Molecular Neurobiology)

Research on Genomics of Crop Stress Tolerance

edited by

Xi Zhu

submission deadline 31 Aug 2027 | 1 articles | Viewed by 706 | Submission Open

Keywords: crop stress tolerance; genomic research; molecular mechanisms; multi-omics approaches; epigenetic modifications

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Targeting in Nanoparticle Systems: Precision Therapy, Detoxification, and Environmental Remediation

edited by

Adelina-Gabriela Niculescu

and Dan Eduard Mihəiescu

submission deadline 31 Aug 2027 | Viewed by 417 | Submission Open

Keywords: nanoparticles; nanocomposites; molecular targeting; stimuli-responsive materials; magnetic nanoparticles; surface functionalization; precision therapy; detoxification; decontamination; environmental remediation

(This special issue belongs to the Section Molecular Nanoscience)

Advances in Molecular and Cellular Biology in Neuroscience

edited by

Keigo Kohara

submission deadline 31 Aug 2027 | Viewed by 159 | Submission Open

Keywords: molecular neuroscience; cellular neurobiology; imaging; synaptic plasticity; optogenetics; brain visualization; signal transduction; developmental molecular and cellular biology in neuroscience; neurological disorders

(This special issue belongs to the Section Molecular Neurobiology)

Displaying special issue 3101-3150 on page 63 of 63.

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