New Approaches in Molecular and Cellular Cancer Biology: Translating Basic Research to the Clinic
A Special Issue of International Journal of Molecular Sciences (ISSN 1422-0067) belonging to the section "Molecular Oncology".
Deadline for manuscript submissions: 29 April 2027 | Viewed by 113
Editors
Interests: cancer and anticancer peptides; substance P/neurokinin-1 receptor system; neurokinin-1 receptor antagonists
Special Issues, Collections and Topics in MDPI journals
Interests: brain tumors; brain metastasis; proteomic; phosphoproteomics
Special Issue Information
Dear Colleagues,
Cancer remains one of the leading causes of mortality worldwide, presenting a continuous challenge to global healthcare systems. While conventional treatments like surgery, chemotherapy, radiotherapy and immunotherapy have prolonged survival, their efficacy is frequently limited by systemic toxicity and the inevitable emergence of drug resistance. Recent discoveries in molecular and cellular biology have fundamentally transformed our understanding of tumor heterogeneity and the complexity of signaling networks driving malignancy. However, translating these basic scientific discoveries into successful, long-term clinical interventions remains a critical difficulty. To overcome these limitations, it is essential to explore innovative approaches that decipher and target the precise molecular and cellular mechanisms underlying tumor progression, survival, and evasion.
Accordingly, the main aim of this Special Issue, “New Approaches in Molecular and Cellular Cancer Biology: Translating Basic Research to the Clinic”, is to bring together cutting-edge research that addresses these challenges through novel biological perspectives. We welcome original research articles and comprehensive reviews focusing on innovative molecular targets, intracellular signaling pathways, and cellular interactions within the tumor microenvironment. Key topics of interest include, but are not limited to, cellular plasticity, epigenetic regulation, non-coding RNAs, mechanisms of therapeutic resistance, advanced multi-omics approaches, angiogenesis, anticancer compounds, apoptotic inducers, cytotoxic peptide conjugate-based cancer therapies, kinases, and transcription factors. Studies utilizing novel in vitro or in vivo models to elucidate structure–function relationships of oncogenic drivers are also highly encouraged. Ultimately, we hope this collection provides a comprehensive platform to advance translational oncology, facilitating the development of safer, more accurate, and effective cancer therapies.
Dr. Rafael Coveñas Rodríguez
Guest Editor
Dr. Maruan Hijazi Vega
Guest Editor Assistant
Manuscript Submission Information
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Keywords
- cell signaling
- proteomics
- phosphoproteomics
- mass spectrometry
- kinase inhibitors
- kinase activity
- signaling networks
- computational biology
- peptide receptor antagonists
- anticancer and cancer peptides
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