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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Cellular and Molecular Progression of Cardiovascular Diseases submission deadline 20 Nov 2025 | 11 articles | Viewed by 33035
Keywords: cardiovascular diseases; multi-omics data; biomarkers; molecular level; pathophysiology
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advances in Lupus Erythematosus and Lupus Nephritis: Pathogenesis, Biomarkers and Treatments
edited by
submission deadline 20 Nov 2025 | 9 articles | Viewed by 32730
Keywords: lupus erythematosus; lupus nephritis; SLE; LN; organ damage; pathogenesis; biomarkers; genomic; transcriptomic; metabolomic; treatments; therapeutic
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Regenerative Medicine: Biomaterials and Stem Cell Research
edited by Silvia María Díaz-Prado
submission deadline 20 Nov 2025 | 8 articles | Viewed by 30258
Keywords: regenerative medicine; stem cell; biomaterial; bioprinting; tissue engineering; tissue and organ transplant; organ scarcity
(This special issue belongs to the Section Materials Science)
Advances in the Molecular Biological Effects of Magnetic Fields submission deadline 20 Nov 2025 | 8 articles | Viewed by 28783
Keywords: magnetoreception magnetoperception alternating magnetic field static magnetic field hypomagnetic field cryptochrome radical-pair mechanism zebrafish Aquatic Species
(This special issue belongs to the Section Molecular Biology)
Drug Treatment for Bacterial Infections
edited by Janusz Madaj
submission deadline 20 Nov 2025 | 12 articles | Viewed by 26758
Keywords: bacterial infection; antibiotic-resistant bacteria; new agents in the treatment of bacterial infections; optimization of the use of already registered drugs; single antibacterial agents; combined antibacterial agents; new drug forms
(This special issue belongs to the Section Molecular Pharmacology)
Molecular Mechanisms of Pain and Analgesia
edited by and Hee Young Kim
submission deadline 20 Nov 2025 | 3 articles | Viewed by 21258
Keywords: pain; analgesia; sensory transmission and integration; molecular pathways; pain genes; drug targets
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Inflammatory Bowel Disease: Molecular Advances in Pathogenesis and Therapies
edited by
submission deadline 20 Nov 2025 | 15 articles | Viewed by 20455
Keywords: Crohn’ s disease; inflammatory bowel disease; immunologic and molecular mechanisms; therapies for IBD; ulcerative colitis
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advanced Research on Lipid Signaling Molecules
edited by Roberta Ottria
submission deadline 20 Nov 2025 | 4 articles | Viewed by 20338
Keywords: endocannabinoid hydrolytic enzyme inhibitors; endocannabinoids; oxylipins; eicosanoids; lipid signaling (fatty acid derivatives); protectins; maresins; and resolvins
(This special issue belongs to the Section Molecular Biology)
Understanding the Mechanisms of Mitochondrial Stress and Its Association with Human Diseases
edited by
submission deadline 20 Nov 2025 | 6 articles | Viewed by 19181
Keywords: mitochondrial stress; mitochondrial quality control; mitophagy; mitochondrial unfolded protein response; mitochondrial fission and fusion; mitochondria-related diseases
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advances in Plant Metabolite Research
edited by
submission deadline 20 Nov 2025 | 8 articles | Viewed by 18950
Keywords: metabolomics; regulatory networks; metabolic engineering; plant secondary metabolic defense; phytochemicals; antioxidant properties; mass spectrometry imaging; biotechnological applications; plant biochemistry
(This special issue belongs to the Section Molecular Plant Sciences)
Drosophila: A Versatile Model in Biology and Medicine—2nd Edition submission deadline 20 Nov 2025 | 12 articles | Viewed by 17651
Keywords: model organism; human disease; inherited disease; cancer; neurodegeneration; rare disease; genetics
(This special issue belongs to the Section Molecular Biology)
Female Infertility and Fertility submission deadline 20 Nov 2025 | 4 articles | Viewed by 16956
Keywords: infertility; embryo; implantation; placenta; endometrium; gynecological endocrinology; assisted reproduction technology; ovaries; inflammation; endometriosis
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Omics Science and Research in Human Health and Disease
edited by Elisa De Paolis
submission deadline 20 Nov 2025 | 7 articles | Viewed by 16089
Keywords: genomics; transcriptomics; proteomics; metabolomics; single-cell analysis; spatial transcriptomics; bioinformatics; multi-omics
(This special issue belongs to the Section Molecular Biology)
Diet and Oxidative Stress
edited by
submission deadline 20 Nov 2025 | 3 articles | Viewed by 15942
Keywords: diet; antioxidants; personalized medicine; oxidative stress; health and disease
(This special issue belongs to the Section Biochemistry)
Exploring Abiotic Stress in Plants: Mechanisms, Adaptations, and Mitigation Strategies
edited by
submission deadline 20 Nov 2025 | 10 articles | Viewed by 15694
Keywords: abiotic stress; plant physiology; stress tolerance; crop resilience; molecular mechanisms; biotechnological interventions
(This special issue belongs to the Section Molecular Plant Sciences)
Molecular Insights into Reproductive Biology and Related Diseases submission deadline 20 Nov 2025 | 6 articles | Viewed by 15084
Keywords: spermatozoa; oocyte; molecular reproduction; infertility
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Inflammatory Airway Diseases: Diagnosis, Pathology, Molecular Mechanisms and Treatment Options
edited by
submission deadline 20 Nov 2025 | 6 articles | Viewed by 14710
Keywords: inflammatory airway diseases; asthma; COPD; anti-inflammatory
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Research in Prebiotics, Probiotics and Postbiotics: 2nd Edition
edited by and Haruki Kitazawa
submission deadline 20 Nov 2025 | 6 articles | Viewed by 14657
Keywords: probiotics; prebiotics; postbiotics; symbiotics; immunobiotics; functional foods; health improvement; mucosal immunology; microbiota
(This special issue belongs to the Section Molecular Microbiology)
Drug Design and Development for Neurological Diseases submission deadline 20 Nov 2025 | 6 articles | Viewed by 14494
Keywords: neurological disorders and their therapies; molecular modeling; synthesis and structural analysis; neurotransmitters ligands; mechanism of action; drug repurposing
(This special issue belongs to the Section Molecular Pharmacology)
Medicinal Plants and Natural Compounds in Health and Disease: Progresses, Challenges, Opportunities, 2nd Edition submission deadline 20 Nov 2025 | 2 articles | Viewed by 14328
Keywords: medicinal plants; phytochemicals; vitamins; oxidative stress; gene expression; protein expression; cellular signaling; ethnopharmacology
(This special issue belongs to the Section Molecular Pharmacology)
Physiology and Molecular Medicine of Molecular Hydrogen
edited by and John Nagi Kheir
submission deadline 20 Nov 2025 | 2 articles | Viewed by 13961
Keywords: molecular hydrogen; reactive oxygen species; nitric oxide; inflammation; cardiovascular disease
(This special issue belongs to the Section Molecular Biology)
Skeletal Muscle Function and Metabolism: Molecular Mechanisms and Treatment—2nd Edition
edited by
submission deadline 20 Nov 2025 | 5 articles | Viewed by 13159
Keywords: skeletal muscle; metabolism; mitochondria; epigenetics; exercise; signalization
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Cardiovascular Disease and Diabetes: A New Challenge in Treatment and Management
edited by Graziano Riccioni
submission deadline 20 Nov 2025 | 4 articles | Viewed by 12837
Keywords: hypertension; atherosclerosis; congestive heart failure; diabetes mellitus; therapy; hypercholesterolemia; coronary artery disease
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Coronavirus Disease (COVID-19): Pathophysiology (6th Edition) submission deadline 20 Nov 2025 | 4 articles | Viewed by 12649
Keywords: SARS-CoV-2; coronavirus; pandemic; viral diseases; pediatrics; inflammation; immune cells; macrophages; pneumonia; vaccines; cytokines; cytokine storm; PIMS; immunity
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Splice-Switching Antisense Oligonucleotides: 30 Years After Advocating Exon-Skipping Therapy for Duchenne Muscular Dystrophy
edited by
submission deadline 20 Nov 2025 | 3 articles | Viewed by 12638
Keywords: antisense oligonucleotides; modified nucleic acid; splicing; splicing switch; exon skipping; pseudoexon; N-of-1; precision medicine
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Microbial Infections and Novel Biological Molecules for Treatment
edited by Matthew Cheesman
submission deadline 20 Nov 2025 | 9 articles | Viewed by 12486
Keywords: microbial infections; infectious diseases; new antibiotics; antimicrobial resistance (AMR); antimicrobial drugs; active substance; bacterial; virus
(This special issue belongs to the Section Molecular Microbiology)
Plant Development and Hormonal Signaling
edited by
submission deadline 20 Nov 2025 | 6 articles | Viewed by 12361
Keywords: plant growth; reproductive growth; phytohormones; signal transduction; transcription factors; root development; shoot development; floral development; seed development; environmental interactions; regulatory networks; apical dominance
(This special issue belongs to the Section Molecular Plant Sciences)
Cardiovascular Diseases: From Pathology to Therapeutics
edited by
submission deadline 20 Nov 2025 | 4 articles | Viewed by 12167
Keywords: cardiovascular diseases; pathologies; cardiac progenitor cells; molecular pathways; regenerative medicine
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Recent Advances in Gastrointestinal Tract Oncology: Pathology, Diagnostics and Therapy
edited by and Mariusz Gryko
submission deadline 20 Nov 2025 | 7 articles | Viewed by 11807
Keywords: gastrointestinal cancer; esophageal cancer; gastric (stomach) cancer; colorectal cancer; liver cancer; pancreatic cancer; gallbladder and biliary tract cancer; genetic alterations; molecular subtyping; tumor microenvironment; innovative therapies; targeted therapies; tumor biomarkers
(This special issue belongs to the Section Molecular Oncology)
Signaling and Stress Adaptation in Plants
edited by and
submission deadline 20 Nov 2025 | 8 articles | Viewed by 11805
Keywords: plants; environmental stress; stress signaling; reactive oxygen/nitrogen species; calcium; protein kinases; stress resistance; adaptive mechanisms
(This special issue belongs to the Section Molecular Plant Sciences)
Recent Advances in Antimicrobial Nanoparticles submission deadline 20 Nov 2025 | 1 articles | Viewed by 10947
Keywords: nanotechnology; antimicrobial agents; nanoparticle synthesis; biomedical applications; targeted delivery; mechanisms of action
(This special issue belongs to the Section Molecular Nanoscience)
Bacteriophage—Molecular Studies (6th Edition)
edited by
submission deadline 20 Nov 2025 | 5 articles | Viewed by 10883
Keywords: bacteriophage biodiversity; regulation of bacteriophage development; molecular processes in bacteriophages; bacteriophage-based biotechnology; phage therapy
(This special issue belongs to the Section Biochemistry)
Cheminformatics in Drug Discovery and Green Synthesis
edited by
submission deadline 20 Nov 2025 | 6 articles | Viewed by 10856
Keywords: cheminformatics; drug discovery; databases; in silico methods; green chemistry
(This special issue belongs to the Section Molecular Informatics)
Insights in Reproductive Immunology and Placental Pathology, 2nd Edition
edited by
submission deadline 20 Nov 2025 | 5 articles | Viewed by 10801
Keywords: gamete immunology; in vitro fertilization; infertility; immunocontraception; implantation; placentation; immunotolerance; reproductive immunology; inflammation; cytokine network; placenta-derived stem cells; placental development; placental insufficiency; endometriosis; immunopathology of pregnancy; sex hormones
(This special issue belongs to the Section Molecular Immunology)
Sjogren's Disease: Multidimensional Perspectives on Pathogenesis, Clinical Manifestations, and Therapeutic Advancements
edited by
submission deadline 20 Nov 2025 | 7 articles | Viewed by 10691
Keywords: Sjö gren's disease; diagnosis; therapeutics; bioinformatics; pre-clinical; cytokine; lymphocytes; autoantibodies; exocrine glands
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advanced Research on Chemokines and Chemokine Receptors
edited by
submission deadline 20 Nov 2025 | 4 articles | Viewed by 10533
Keywords: chemokines; chemokine receptors; chronic diseases; angiogenesis; fracture; regeneration; chemokine function; expression
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Mechanisms and New Markers of Cancer
edited by
submission deadline 20 Nov 2025 | 5 articles | Viewed by 10373
Keywords: molecular pathology; molecular mechanisms; immunotherapy; cancer; oncology; pathology; biomarkers
(This special issue belongs to the Section Molecular Oncology)
Molecular Mechanisms and Emerging Therapies in Neurovascular Disease
edited by Leonidas D. Panos
submission deadline 20 Nov 2025 | 3 articles | Viewed by 9956
Keywords: neurovascular diseases; blood– brain barrier; endothelial dysfunction; cellular signaling; gene therapy
(This special issue belongs to the Section Molecular Neurobiology)
Abnormal Organelles and Protein Expression in Acute and Chronic Neurodegeneration
edited by
submission deadline 20 Nov 2025 | 3 articles | Viewed by 9902
Keywords: brain ischemia; epileptic damage; basal ganglia pathology; catecholamine cell damage; excitotoxicity; autophagy; dopamine system norepinephrine system; protein unfolding; protein misfolding; cholinergic system
(This special issue belongs to the Section Molecular Neurobiology)
Involvement of Neuroinflammatory Processes in Psychiatric Conditions
edited by
submission deadline 20 Nov 2025 | 4 articles | Viewed by 9744
Keywords: neuroinflammation; glia; chemokine; cytokine; psychiatry disorder; motivation; learning; behavior; mental illness; psychopharmacology
(This special issue belongs to the Section Molecular Neurobiology)
New Insights into Mitochondria in Health and Diseases submission deadline 20 Nov 2025 | 5 articles | Viewed by 9646
Keywords: mitochondrial bioenergetics; reactive oxygen species; apoptosis; aging; immune function; mtDNA mutations; mitochondrial dysfunction; mitochondria-targeted therapies
(This special issue belongs to the Section Biochemistry)
Astrocyte-Endothelial Interactions at the Blood-Brain Barrier, 2nd Edition
edited by
submission deadline 20 Nov 2025 | 3 articles | Viewed by 9639
Keywords: blood– brain barrier (BBB); astrocyte– endothelial interactions; cytokine signaling; astrocytic modulation; brain microvascular endothelial cells; chemokine receptors; BBB permeability; BBB dysfunction; BBB pharmacokinetics; cerebrovascular disease; oxidative stress; BBB models
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Insights in Antivirals and Vaccines submission deadline 20 Nov 2025 | 2 articles | Viewed by 9627
Keywords: new vaccine platforms; cell cultures; plant molecular farming; vaccines and VLPs; nanoparticle vaccines; emerging viral diseases; novel therapeutics; biologics; antibodies; receptor modulators; plant-based compounds with antiviral activity; medicinal plant-derived products; bioactive proteins from plants
(This special issue belongs to the Section Molecular Microbiology)
Progress in New Agents to Treat Breast Cancer
edited by Eileen Brantley
submission deadline 20 Nov 2025 | 4 articles | Viewed by 9435
Keywords: breast cancer; chemotherapeutic agents; DNA-alkylating drugs; anthracyclines; antimetabolites; taxanes
(This special issue belongs to the Section Molecular Oncology)
Exploring the Molecular Mechanisms of Chronic Kidney Disease submission deadline 20 Nov 2025 | 5 articles | Viewed by 9342
Keywords: chronic kidney disease; hereditary renal disease; renal hypertension; diabetic nephropathy; secondary hyperparathyroidism; cardiovascular disease; renal osteodystrophy; peritoneal dialysis; hemodialysis; anemia; metabolic acidosis
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Antioxidant and Antibacterial Properties of Phytochemicals
edited by and Vytaute Starkute
submission deadline 20 Nov 2025 | 5 articles | Viewed by 9163
Keywords: phytochemicals; natural preservatives; antioxidants; antibacterial properties; food; cosmetics; pharmaceuticals; animal feed
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Molecular Research in Cardiovascular Disease, 3rd Edition submission deadline 20 Nov 2025 | 6 articles | Viewed by 8705
Keywords: atherosclerosis; cardiovascular disease; endothelial cells; matrix metalloproteinases; biomarkers; miRNAs; epigenetics
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
The Molecular Basis of Plant–Microbe Interactions submission deadline 20 Nov 2025 | 3 articles | Viewed by 8593
Keywords: plant immune and defense responses; microbe and microbiome function; microbial biodiversity; abiotic and biotic stress mitigation; gene regulatory mechanisms; plant hormones in plant– microbe interactions; molecular mechanisms of plant growth and microbe interactions; chemical communication in plant– microbe interactions; microbe effects on fruit quality; OMICs approaches (metagenomics; metatranscriptomics; epigenomics; transcriptomics; metabolomics); bioinformatics
(This special issue belongs to the Section Molecular Plant Sciences)
Recent Research of Natural Products from Microalgae and Cyanobacteria
edited by
submission deadline 20 Nov 2025 | 4 articles | Viewed by 8519
Keywords: marine and fresh water microalgal and cyanobacterial bioactive compounds; microalgal and cyanobacterial carotenoids; vitamins; phenolics; and phycobiliproteins; microalgal and cyanobacterial alkaloids; microalgal and cyanobacterial polysaccharides; microalgal and cyanobacterial peptides; microalgal and cyanobacterial polyphenols; microalgal and cyanobacterial antioxidants; microalgal and cyanobacterial pharmaceuticals; microalgal and cyanobacterial nutraceuticals; microalgal and cyanobacterial anti-inflammatory compounds; microalgal and cyanobacterial antimicrobial compounds; microalgal and cyanobacterial anticancer compounds; microalgal and cyanobacterial neuroprotective compounds; microalgal and cyanobacterial antiviral compounds; microalgal and cyanobacterial-derived anti-aging compounds; microalgal and cyanobacterial extracts
(This special issue belongs to the Section Biochemistry)
Advanced Perspectives on Virus–Host Interactions
edited by
submission deadline 20 Nov 2025 | 6 articles | Viewed by 8384
Keywords: viral manipulation of host metabolics; virus– host interactions; host– pathogen co-evolution; susceptibility and resistance to viral infection; novel antiviral strategies
(This special issue belongs to the Section Molecular Microbiology)
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