Cellular and Molecular Progression of Cardiovascular Diseases

Dear Colleagues,

Cardiovascular diseases (CVDs) are the leading cause of death globally, claiming an estimated 18 million lives annually. Despite extensive research, gaining novel insights into the pathophysiology and molecular mechanisms of CVDs through both basic and clinical research is crucial. This effort is essential for identifying new diagnostic/prognostic tools and developing therapeutic strategies that can enhance patient management and outcomes.

The integration of multi-omics data (including genomics, epigenomics, transcriptomics, proteomics, and metabolomics) offers a holistic perspective on the patient, providing insights into regulatory mechanisms, pathways, and networks involved in the development and progression of CVDs. Furthermore, artificial intelligence (AI) stands out as a powerful framework capable of recognizing complex patterns within large-scale clinical and molecular data. Its potential to improve risk prediction is substantial, allowing for the identification of biomarkers for more accurate diagnoses, the prediction of treatment outcomes, and the development of novel therapies for personalized approaches.

For this Special Issue, we invite investigators to contribute original research and review papers. The aim is to cover the most recent advances in the molecular and cellular mechanisms underlying CVDs. Manuscripts that also discuss the value of AI-related strategies in Molecular Level.

Dr. Andrea Borghini
Dr. Antonio Rizza
Dr. Alessandro Tonacci
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• cardiovascular diseases
• multi-omics data
• biomarkers
• molecular level
• pathophysiology