Molecular Research in Cardiovascular Disease, 3rd Edition
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (30 March 2025) | Viewed by 417
Special Issue Editor
2. Department 4-Cardiothoracic Pathology, University of Medicine and Pharmacy Carol Davila, 8, Eroii Sanitari Bvd., 050474 Bucharest, Romania
Interests: ischemic heart disease; atherosclerosis; molecular mechanisms of acute coronary syndromes; arterial hypertension; hypertensive target organ damage
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cardiovascular diseases (CVD) are the leading cause of death worldwide. Atherosclerosis, the dominant driver of CVD, is characterized by a process of chronic inflammation and endothelial dysfunction associated with vessel wall accumulation of oxidized low-density lipoproteins.
In advanced stages, endothelial lesions promote atherosclerotic plaque instability, acute events, and ultimately, plaque rupture.
The molecular and cellular mechanisms underlying various cardiovascular diseases are not completely understood. However, several signaling pathways that induce vascular remodeling are essential in both coronary heart disease and in related pathologies, such as pulmonary artery hypertension, suggesting the existence of common mechanisms in these maladies.
With this Special Issue, we aim to present representative data obtained at the interface between basic science and clinical research on the molecular mechanisms of heart and vascular diseases and the novel biomarkers and molecules that can become specific targets for future therapeutic interventions. In addition, we hope that the papers presented will inspire novel innovative investigations at the bench to bedside intersection.
Due to the success of the first and second editions of this Special Issue, we would like to add more results and new insights from recent research projects (https://www.mdpi.com/journal/ijms/special_issues/Molecular_Research_Cardiovascular_Disease, https://www.mdpi.com/journal/ijms/special_issues/Cardiovascular_Disease_2).
Prof. Dr. Maria Dorobantu
Guest Editor
Manuscript Submission Information
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Keywords
- atherosclerosis
- cardiovascular disease
- endothelial cells
- matrix metalloproteinases
- biomarkers
- miRNAs
- epigenetics
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