Physiology and Molecular Medicine of Molecular Hydrogen
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 20 November 2025 | Viewed by 4218
Special Issue Editors
2. Molecular Hydrogen Institute, Cedar City, UT 84720, USA
Interests: molecular hydrogen; reactive oxygen species; nitric oxide; inflammation; cardiovascular disease
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Molecular hydrogen (H2 gas) has emerged as a fascinating molecule with the ability to penetrate biomembranes and access subcellular compartments. Recent research has unveiled its diverse therapeutic effects, spanning its antioxidant, anti-inflammatory, and antiapoptotic activities. Moreover, H2 has been shown to influence microRNA expression, protein phosphorylation cascades, and various signal transduction pathways. Demonstrating its versatility, hydrogen’s therapeutic potential has been explored in over 170 different animal/human disease models, encompassing a wide array of human physiological systems. Yet, despite these advancements, significant gaps persist within our understanding of the mechanistic actions of molecular hydrogen, its clinical viability, and the optimal dosage, frequency, and treatment duration.
In light of this, our Special Issue aims to gather contributions that advance the exploration of molecular hydrogen’s therapeutic utility. We welcome submissions encompassing both in vitro cellular mechanistic studies and in vivo investigations in animal models and human clinical settings. Original research articles, reviews, perspectives, and short communications are all encouraged, provided they contribute to our understanding of the pharmacokinetics, pharmacodynamics, and therapeutic applications of molecular hydrogen.
We invite you to join us in this endeavor to delve deeper into the potential of molecular hydrogen as a therapeutic agent.
In the meantime, the H2 Summit hosted by me and Dr. John Nagi Kheir is being prepared. The link to the meeting is as follows: https://h2mhisummit.org/h2-summit/. We sincerely invite you to attend and forward to let more scholars know about molecular hydrogen.
Dr. Tyler W. LeBaron
Dr. John Nagi Kheir
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- molecular hydrogen
- reactive oxygen species
- nitric oxide
- inflammation
- cardiovascular disease
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