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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Nanobiomaterials for Medical Research: From Molecular Mechanisms to Clinical Translation

edited by

Carmen Curutiu

Alina Maria Holban

and

Florin Iordache

submission deadline 31 Mar 2027 | 1 articles | Viewed by 1064 | Submission Open

Keywords: nanomaterials; biopolymers; medical research; chronic diseases; molecular mechanisms

(This special issue belongs to the Section Molecular Nanoscience)

Advances in Antimicrobial Resistance: Molecular and Biochemical Perspectives

edited by

Emanuela Santoro

submission deadline 31 Mar 2027 | 1 articles | Viewed by 1048 | Submission Open

Keywords: antimicrobial resistance mechanisms; molecular basis of resistance; metabolic reprogramming in bacteria; biofilm formation and regulation; resistance gene expression and regulation

(This special issue belongs to the Section Molecular Microbiology)

Molecular and Immunological Mechanisms Associated with Exercise

edited by

Sebastian Del Rosso

submission deadline 31 Mar 2027 | 1 articles | Viewed by 1028 | Submission Open

Keywords: signaling pathways; exercise training adaptation; exercise and mitochondrial health; skeletal muscle secretome; exercise and extracellular vesicles; myokines; exerkines; molecular immune responses to exercise

(This special issue belongs to the Section Molecular Biology)

Muscle Atrophy Molecular Signaling Regulation

edited by

Tatiana Kostrominova

submission deadline 31 Mar 2027 | 1 articles | Viewed by 1019 | Submission Open

Keywords: skeletal muscle atrophy; loss of mass and contractile force; molecular signaling pathways

(This special issue belongs to the Section Molecular Biology)

T Cell Immunity in Emerging Respiratory Viral Infections: Mechanisms, Dysregulation, and Therapeutic Targets

edited by Jian Zheng

submission deadline 31 Mar 2027 | 1 articles | Viewed by 1017 | Submission Open

Keywords: T cell; coronavirus; immune memory; immunopathogenesis; aging

(This special issue belongs to the Section Molecular Immunology)

Advances in Biophysical Studies on Lipid Membranes

edited by Wallance Moreira Pazin

submission deadline 31 Mar 2027 | 1 articles | Viewed by 1006 | Submission Open

Keywords: membrane biophysics; lipid organization; lipid–protein interactions; molecular dynamics simulations; membrane mechanics; nanoscale transport; model membrane systems; biomolecular interactions; membrane structure and dynamics; molecular-level characterization

(This special issue belongs to the Section Molecular Biophysics)

Crucial Role of Intestinal Barriers and Their Impact on the Gut–Brain Axis in Health and Disease: Addressing Future Therapies

edited by

Elzbieta M. Sajdel-Sulkowska

submission deadline 31 Mar 2027 | 1 articles | Viewed by 1003 | Submission Open

Keywords: age; brain–gut microbiota axis; intestinal barrier; fetal; gender; sex

(This special issue belongs to the Section Molecular Biology)

Recent Research on Noble Metal Nanoparticles

edited by

Shinmori Hideyuki

submission deadline 31 Mar 2027 | 2 articles | Viewed by 1000 | Submission Open

Keywords: nanostructure; gold nanoparticles; silver nanoparticles; heterometallic nanoparticles; core–shell structure; surface chemistry; colloid chemistry; localized surface plasmon resonance

(This special issue belongs to the Section Molecular Nanoscience)

Molecular and Cellular Advances in Coagulation and Bleeding

edited by

Muriel Meiring

submission deadline 31 Mar 2027 | 1 articles | Viewed by 993 | Submission Open

Keywords: thrombosis; haemostasis; inflammation-coagulation cross ralk; proteomics; molecular biomarkers

(This special issue belongs to the Section Molecular Biology)

Animal Reproduction and Development: Current Issues and Future Perspectives

edited by

Kamil Janelt

submission deadline 31 Mar 2027 | 2 articles | Viewed by 985 | Submission Open

Keywords: reproductive and developmental biology; molecular and cellular mechanisms; gene regulation and epigenetics; physiology and metabolic regulation; biotechnology and translational research

(This special issue belongs to the Section Molecular Biology)

Molecular Mechanism and Pathogenesis of Neuroinflammation in Neurological Disorders

edited by

Masashi Tanaka

submission deadline 31 Mar 2027 | Viewed by 954 | Submission Open

Keywords: age-related disorders; Alzheimer’s disease; amyloid-β; bioactive molecules; cognitive impairment; dementia; glial activation; microglia; neuroinflammation; neurological disorders; neurotherapeutics; tau hyperphosphorylation

(This special issue belongs to the Section Molecular Neurobiology)

State-of-the-Art Bioactives and Nutraceuticals in Thailand

edited by Lalita Chotphruethipong

submission deadline 31 Mar 2027 | 1 articles | Viewed by 894 | Submission Open

Keywords: phytochemicals; advanced extraction technologies; therapeutic mechanisms; bioavailability enhancement; botanical valorization; functional food matrices

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Medicinal Plants: Molecular Dissection of Active Compounds

edited by

Moxian Chen

and

Abazar Ghorbani

submission deadline 31 Mar 2027 | 2 articles | Viewed by 891 | Submission Open

Keywords: medicinal plants; active compounds; secondary metabolites; biosynthetic pathways; metabolic regulation; terpenoids; flavonoids; multi-omics; metabolic engineering; bioactivity

(This special issue belongs to the Section Molecular Plant Sciences)

Detrimental and Beneficial Roles of Glial Cells After Neural Disorders

edited by

Walace Gomes-Leal

submission deadline 31 Mar 2027 | Viewed by 887 | Submission Open

Keywords: neuroprotection; neuroinflammation; cell therapy; microglia; astrocytes; oligodendrocytes; Janus face; double-edged sword

(This special issue belongs to the Section Molecular Neurobiology)

Advanced Molecular Research on Diabetes Pharmacology

edited by

Ioanna A. Anastasiou

submission deadline 31 Mar 2027 | 1 articles | Viewed by 842 | Submission Open

Keywords: diabetes; pharmacology; antidiabetic drugs; insulin therapy; SGLT2 inhibitors; GLP-1 receptor agonists; combination therapy; personalized medicine; drug development

(This special issue belongs to the Section Molecular Pharmacology)

Molecular and Histological Advance in Neural Regeneration

edited by Wiktor Pascal

submission deadline 31 Mar 2027 | 1 articles | Viewed by 839 | Submission Open

Keywords: neural regeneration; peripheral nerve injury; central nervous system; Schwann cells; axonal regeneration; stem cells; neurotrophic factors; biomaterials; histology; molecular mechanisms

(This special issue belongs to the Section Molecular Neurobiology)

Artificial Intelligence in Drug Design: Molecular Aspects

edited by

Dorota Latek

submission deadline 31 Mar 2027 | 1 articles | Viewed by 825 | Submission Open

Keywords: artificial intelligence; machine learning; drug design; medical imaging; apoptosis; metastasis; anticancer therapy

(This special issue belongs to the Section Molecular Pharmacology)

Epitranscriptomics: RNA Modifications and Function

edited by Caroline Vissers

submission deadline 31 Mar 2027 | 1 articles | Viewed by 817 | Submission Open

Keywords: epitranscriptome; methylation; mRNA; rRNA; RNA modifications

(This special issue belongs to the Section Molecular Genetics and Genomics)

Mathematical Calculation and Modeling in Biology

edited by Nan Sheng

submission deadline 31 Mar 2027 | 1 articles | Viewed by 795 | Submission Open

Keywords: mathematical modeling; computational biology; machine/deep learning; molecular biology; molecular interactions; gene; protein; small molecule; computational drug design; multi-omics

(This special issue belongs to the Section Molecular Informatics)

Novel Metallic Biomaterials: From Research to Clinical Translation

edited by Ke Yang

submission deadline 31 Mar 2027 | 1 articles | Viewed by 791 | Submission Open

Keywords: metallic biomaterials; bio-functionality; biocompatibility; mechanical properties; clinical application

(This special issue belongs to the Section Materials Science)

Molecular Targets in Reproductive Diseases

edited by

Changwon Yang

submission deadline 31 Mar 2027 | 1 articles | Viewed by 762 | Submission Open

Keywords: reproductive diseases; endometriosis; polycystic ovary syndrome; infertility-related disorders; pregnancy complications; reproductive system cancers; reproductive medicine; precise diagnosis; targeted therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Bioactive Peptides: Function, Metabolism and Synthesis

edited by

Leandro Mantovani de Castro

submission deadline 31 Mar 2027 | Viewed by 712 | Submission Open

Keywords: bioactive peptides; antimicrobial peptides; antitumoral peptides; neurodegenerative diseases; metabolic diseases; chemical synthesis; cellular proteolysis; mass spectrometry; peptidomics; intracellular peptides; micropeptides

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Exploring Glia: New Insights into Neurobiology and Therapeutic Potential

edited by María de los Ángeles García-Robles

submission deadline 31 Mar 2027 | Viewed by 693 | Submission Open

Keywords: glial metabolism; astrocytes; microglia; oligodendrocytes; tanycytes; obesity; diabetes; metabolic disorders; neurogenesis; cognitive decline

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Pathophysiology of Lung Diseases—2nd Edition

edited by

Theodoros Karampitsakos

and Vassilios Tzilas

submission deadline 31 Mar 2027 | Viewed by 670 | Submission Open

Keywords: biomarkers; asthma; COPD; pulmonary fibrosis; post-COVID-19; interstitial lung disease; pathogenesis; personalized medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular and Cellular Mechanisms of Scaffold-Based Tissue Engineering

edited by

Inseon Kim

submission deadline 31 Mar 2027 | 1 articles | Viewed by 661 | Submission Open

Keywords: scaffold; tissue engineering; extracellular matrix; biomaterials; 3D bioprinting; mechanobiology; stem cell differentiation; cultivated meat

(This special issue belongs to the Section Molecular Biology)

Molecular Mechanisms and Immune Regulation in Prostate Cancer

edited by Nigel Peter Murray

submission deadline 31 Mar 2027 | 1 articles | Viewed by 644 | Submission Open

Keywords: prostate cancer; immunosupressision; molecular changes; tumour microenvironment; anti-tumour immune changes; next-generation methods of molecular investigation

(This special issue belongs to the Section Molecular Oncology)

Molecular Mechanisms in Glomerular and Renal Diseases

edited by Eleni Stamellou and

Evangelia Dounousi

submission deadline 31 Mar 2027 | 1 articles | Viewed by 641 | Submission Open

Keywords: glomerulonephritis (GN); podocytopathies; IgA (IgAN); chronic kindey disease (CKD); membra-nous nephropathy; focal segmental glomerulosclerosis (FSGS)

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Emerging Biomarkers in Airway Diseases: From Epigenetic Regulation to Cellular Stress Pathways

edited by

Giusy Daniela Albano

submission deadline 31 Mar 2027 | 1 articles | Viewed by 641 | Submission Open

Keywords: airway diseases; asthma; chronic obstructive pulmonary disease; chronic rhinosinusitis; virus-associated airway disorders

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Podocyte Research: Molecular Insights and Clinical Applications

edited by

Hans Lorenzo

submission deadline 31 Mar 2027 | Viewed by 611 | Submission Open

Keywords: podocytes; glomerular filtration barrier; slit diaphragm; podocyte injury; proteinuria; focal segmental glomerulosclerosis; nephrotic syndrome; cell death; non-coding RNAs; therapeutic targets

(This special issue belongs to the Section Molecular Biology)

Current Trends in Organometallic Chemistry and Its Applications

edited by

Senka Djaković

and Jasmina Lapić

submission deadline 31 Mar 2027 | 1 articles | Viewed by 602 | Submission Open

Keywords: (bio)organometallic chemistry; synthesis; application; structure–property relationships; computational modelling; ligand design; biomedical materials

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Single Cell Transcriptomics in Human Disease

edited by

Md. Mahmudul Hasan

submission deadline 31 Mar 2027 | 1 articles | Viewed by 595 | Submission Open

Keywords: single-cell RNA sequencing; brain aging; neurodegeneration; cellular heterogeneity; transcriptomics; neuronal aging; glial cells; senescence; cognitive decline; spatial transcriptomics

(This special issue belongs to the Section Molecular Biology)

Research Progress in Food Packaging Materials

edited by

Anouar Mouhoub

submission deadline 31 Mar 2027 | 1 articles | Viewed by 595 | Submission Open

Keywords: molecular design; intermolecular interactions; structure–property relationships; bio-based polymers; controlled release systems; active packaging; sustainable materials

(This special issue belongs to the Section Materials Science)

Molecular Antimicrobial Resistance in Cancers

edited by Nicola Silvestris and Massimo Andreoni

submission deadline 31 Mar 2027 | Viewed by 560 | Submission Open

Keywords: antimicrobial resistance; host–pathogen interaction; immune dysfunction; immunosuppression; infection; biomarker; novel antimicrobials; cancer; frail patient

(This special issue belongs to the Section Molecular Oncology)

Kidney Transplantation: Current Framework and New Perspectives

edited by Alberto Rosati

submission deadline 31 Mar 2027 | 1 articles | Viewed by 552 | Submission Open

Keywords: renal transplantation; organ donation; living donation; transplant survival; organ preservation; healthcare costs; acute and chronic rejection; immune tolerance; xenotransplantation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular and Nanoscience Approaches to Neurodevelopmental Disorders

edited by

Khairunnuur Fairuz Azman

submission deadline 31 Mar 2027 | Viewed by 532 | Submission Open

Keywords: neurodevelopment; molecular neuroscience; neurotrophic signaling; epigenetics; synaptic plasticity; neuroinflammation; neurodevelopmental disorders; biomarkers; nanoneuroscience; nanotechnology

(This special issue belongs to the Section Molecular Neurobiology)

Advanced Strategies for Melanoma Immunotherapy

edited by

Andrzej Mackiewicz

and

Piotr Rutkowski

submission deadline 31 Mar 2027 | Viewed by 523 | Submission Open

Keywords: melanoma immunotherapy; immune Checkpoint Inhibitors; combination therapies; biomarkers; tumor microenvironment

(This special issue belongs to the Section Molecular Immunology)

Advancing Mental Disorder Therapies: Drug Repositioning and Translational Insights from Animal Models

edited by Claudia Bregonzio and Mariela Fernanda Pérez

submission deadline 31 Mar 2027 | Viewed by 512 | Submission Open

Keywords: anxiety; depression; Parkinson's disease; Alzheimer; schizophrenia; neurotransmitter imbalance; novel treatments; new pharmacological targets; preclinical studies

(This special issue belongs to the Section Molecular Neurobiology)

Antibiotic Resistance: Recent Developments and Future Prospects

edited by

Awais Ghaffar

submission deadline 31 Mar 2027 | 1 articles | Viewed by 511 | Submission Open

Keywords: antimicrobial resistance detection; microbial ecology; shotgun metagenomics; genome-resolved metagenomics; microbiome analysis; resistome characterization; One Health

(This special issue belongs to the Section Molecular Pharmacology)

Calcium Dynamics in Disease: Mechanisms and Therapeutic Opportunities

edited by

Valeria Magnelli

submission deadline 31 Mar 2027 | Viewed by 494 | Submission Open

Keywords: calcium signaling; homeostasis; deregulation; calcium imbalance

(This special issue belongs to the Section Biochemistry)

Depression: From Molecular Basis to Therapy—3rd Edition

edited by

Terezia Kiskova-Simkova

submission deadline 31 Mar 2027 | Viewed by 491 | Submission Open

Keywords: depression; neurobiology; molecular basis; neurotransmitters; genetic factors; psychopharmacology; psychotherapy; genetic markers

(This special issue belongs to the Section Molecular Neurobiology)

Peripheral Neuropathy: Exploring Pathogenic Pathways and Therapeutic Approaches

edited by Yuehling Hsieh

submission deadline 31 Mar 2027 | Viewed by 486 | Submission Open

Keywords: peripheral neuropathy; biochemical mechanisms; biomarkers; nerve regeneration; therapeutic approaches; pain management; denervated muscle atrophy; translational medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Emerging Pharmacological Targets and Therapeutic Strategies in Diabetes and Obesity

edited by

Roma Patel

submission deadline 31 Mar 2027 | 1 articles | Viewed by 483 | Submission Open

Keywords: diabetes; obesity; molecular pharmacology; therapeutic targets; insulin resistance; β-cell dysfunction; metabolic signaling pathways; adipose tissue biology; drug–target interactions

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Molecular Pathogenesis and Treatments of Pediatric Leukemias

edited by

Joanna Zawitkowska

submission deadline 31 Mar 2027 | Viewed by 474 | Submission Open

Keywords: monoclonal antibodies; tyrosine kinase inhibitors; CAR-T; chemotherapy; drug induced toxicity

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Pathogenic Escherichia coli: Cellular Biology, Mechanisms of Pathogenesis, Therapeutic Approaches and Strategies for Disease Intervention

edited by

Jorge Goldstein

submission deadline 31 Mar 2027 | Viewed by 472 | Submission Open

Keywords: enterohemorrhagic E. coli; EHEC; Shiga toxin-producing E. coli; STEC; HUS; inflammation; kidney; blood; brain; pathogenesis; antibodies; extraintestinal pathogenic E. coli; E. coli pathotypes

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Unraveling the Host–Virus Interplay in Viral Infection: Molecular Mechanisms and Therapeutic Horizons

edited by

Agustín Valenzuela-Fernández

and

Romina Cabrera-Rodríguez

submission deadline 31 Mar 2027 | Viewed by 466 | Submission Open

Keywords: host–virus interplay; viral infection; molecular mechanisms; antiviral defenses; molecular tools for diagnosis and therapies

(This special issue belongs to the Section Molecular Biology)

DNA Damage and DNA Repair in Health and Diseases

edited by Silvina B. Nadin

submission deadline 31 Mar 2027 | Viewed by 465 | Submission Open

Keywords: genome instability; DNA damage response; DNA repair mechanisms; cancer; therapeutic targets; preclinical studies; translational studies; DNA repair and immune system; PARP inhibitors; BRCA1/2

(This special issue belongs to the Section Molecular Biology)

Emerging Role of Heterogeneous Catalysis in Materials Science and Application

edited by Alejandro Pérez Larios and

Carlos Soto Robles

submission deadline 31 Mar 2027 | 1 articles | Viewed by 459 | Submission Open

Keywords: heterogeneous photocatalysis; photocatalytic materials; structure–property relationships; catalyst design; surface and interface engineering; operando characterization; charge transfer dynamics; sustainable photocatalysis; CO2 photoconversion; environmental photocatalysis

(This special issue belongs to the Section Materials Science)

Molecular Mechanisms and Combinatorial Strategies in Anti-Obesity Therapeutics

edited by

James Ernest Blevins

submission deadline 31 Mar 2027 | Viewed by 452 | Submission Open

Keywords: obesity; high-fat diet; rodents; pharmacotherapy; body weight; food intake

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Dermatological Perspectives on Connective Tissue Diseases

edited by

Yoshihide Asano

submission deadline 31 Mar 2027 | Viewed by 449 | Submission Open

Keywords: connective tissue diseases; systemic sclerosis; systemic lupus erythematosus; dermatomyo-sitis; rheumatoid arthritis; Sjögren’s syndrome; skin immunology; fibrosis; cytokines; targeted therapy

(This special issue belongs to the Section Molecular Biology)

The Role of miRNAs in Healthy Lungs and Chronic Lung Diseases

edited by Victor Ruiz

submission deadline 31 Mar 2027 | Viewed by 446 | Submission Open

Keywords: miRNA; DROSHA; DICER; DGCR8; ADAR; pulmonary fibrosis; COPD; asthma; lung neoplasm

(This special issue belongs to the Section Molecular Biology)

Displaying special issue 2851-2900 on page 58 of 63.

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