International Journal of Molecular Sciences

Roles and Mechanisms of Non-Coding RNAs in Breast Cancer

edited by

submission deadline 20 Dec 2025 | Viewed by 439 | Submission Open

Keywords: breast cancer; NcRNA; MmiRNA; LncRNA; CircRNA; PiRNA; exosome-packed ncRNA; role and mechanisms of ncRNA in breast cancer tissue or cell lines; modulation of ncRNA levels by knock-out or knock-down approaches; effects on breast cancer cell proliferation; invasion; or apoptosis; identification of BC-relevant ncRNA– mRNA networks; targeting ncRNAs with potential clinical implications

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular and Immunological Biomarkers in Cervical Cancer

edited by Janaina Cristiana de Oliveira Crispim and

Ricardo Ney Oliveira Cobucci

submission deadline 20 Dec 2025 | Viewed by 430 | Submission Open

Keywords: cervical cancer; molecular biomarkers; immunological biomarkers; human papillomavirus (HPV); tumor microenvironment; immune responses; immunotherapy; diagnostic biomarkers; prognostic biomarkers; therapeutic targets

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Protein Modification: New Insights

edited by

Yeou-Guang Tsay

submission deadline 20 Dec 2025 | Viewed by 425 | Submission Open

Keywords: post-translational modifications (PTMs); side chain modifications; backbone modifications; analytical protein chemistry; mass spectrometry

(This special issue belongs to the Section Biochemistry)

Molecular Advances in Chronic Pain: Mechanisms and Therapeutic Innovations

edited by

Roberto Tedeschi

submission deadline 20 Dec 2025 | Viewed by 425 | Submission Open

Keywords: chronic pain; pain mechanisms; pain management; therapeutic innovation; translational research

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Bacteria-Mediated Cancer Therapy: New Molecular Insights

edited by

Che-Hsin Lee

submission deadline 20 Dec 2025 | Viewed by 425 | Submission Open

Keywords: bacteria-mediated cancer therapy; tumor microenvironment (TME); tumour immunotherapy; anticancer bacteria

(This special issue belongs to the Section Molecular Oncology)

Pediatric Autoimmune Diseases: Molecular Basis, Diagnostic and Therapy

edited by

Marija Jelusic

submission deadline 20 Dec 2025 | Viewed by 422 | Submission Open

Keywords: autoimmunity; immune regulation; biomarker analysis; molecular pathways; precision medicine; genetics

(This special issue belongs to the Section Molecular Immunology)

Circumventing Resistance to Channel-Targeting Insecticides: A Challenge for Global Health and Food Security

edited by

Bruno Lapied

and David Barry Sattelle

submission deadline 20 Dec 2025 | Viewed by 421 | Submission Open

Keywords: pest insects and resistance; resistance in insect vectors of human and livestock diseases; mechanisms of resistance; circumventing resistance; ion channels and resistance; integrated approaches to resistance management; alternating insecticide classes; minimizing risk to beneficial insects; novel control strategies

(This special issue belongs to the Section Molecular Biology)

Effects of Xenobiotic Exposure on Human Health: A Molecular Perspective

edited by

Maria Lisa Garavaglia

submission deadline 20 Dec 2025 | Viewed by 418 | Submission Open

Keywords: xenobiotic exposure; human health; toxic effects; environmental chemicals; molecular research

(This special issue belongs to the Section Molecular Toxicology)

Quantum Chemistry, Vibrational Spectroscopy and Biophysics on Biomolecules

edited by

Mauricio Alcolea Palafox

submission deadline 20 Dec 2025 | Viewed by 409 | Submission Open

Keywords: molecular simulations; computer calculations; structure predictions; molecular structure; DNA structure; nucleobases pairs; inter-molecular interactions; spectroscopic predictions; scaling; Raman simulations; macromolecular crystallography; molecular modeling; electronic properties

(This special issue belongs to the Section Molecular Biophysics)

Anticancer Antibiotics: Progresses, Opportunities and Challenges

edited by Jose Kaneti

submission deadline 20 Dec 2025 | Viewed by 387 | Submission Open

Keywords: tetracycline antibiotics; antitumor activity; molecular mechanism; G-quadruplex complexes; computational modeling; pharmacological evaluation

(This special issue belongs to the Section Molecular Pharmacology)

Thrombo-Inflammatory Signaling and Complications in Autoimmune Disorders

edited by

Alexandros Tsoupras

submission deadline 20 Dec 2025 | Viewed by 383 | Submission Open

Keywords: inflammation; thrombosis; platelets; coagulation; autoimmune disorders; rheumatoid arthritis; systematic erythematosus lupus; antiphospholipid syndrome; thrombo-inflammation; antithrombotic; antiplatelet

(This special issue belongs to the Section Molecular Immunology)

Growth Factor Signaling in Cancer Progression

edited by

Hyeong-Reh Choi Kim

and Abdo J. Najy

submission deadline 20 Dec 2025 | Viewed by 382 | Submission Open

Keywords: growth factor signaling; proteolysis; cancer progression; tumor dormancy; metastasis; tumor microenvironment; therapeutic strategies

(This special issue belongs to the Section Molecular Biology)

Antiviral Mechanisms of Natural/Synthetic Compounds

edited by Cybele Carina García

submission deadline 20 Dec 2025 | Viewed by 373 | Submission Open

Keywords: antiviral mechanisms; natural compound; synthetic compound; druggable viral/host target; emerging virus; host– virus interaction; innate antiviral response; cell-intrinsic restriction factor

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Coenzyme Q Redox State and Cellular Homeostasis: Implications for Clinical Practice

edited by

Iain P. Hargreaves

submission deadline 20 Dec 2025 | Viewed by 348 | Submission Open

Keywords: coenzyme Q; cellular homeostasis; cellular energy production; antioxidant defense

(This special issue belongs to the Section Molecular Biology)

Stem Cell or Exosome-Based Therapy for Kidney and Urinary Tract Diseases: Mechanisms, Applications, and Future Perspectives

edited by

Yuanyuan Zhang

submission deadline 20 Dec 2025 | Viewed by 345 | Submission Open

Keywords: stem cell therapy; exosome therapy; kidney disease; regenerative medicine; cell differentiation; tissue engineering; drug discovery; in vitro 3D models; anti-inflammation; antioxidant stress; antifibrosis; extracellular vesicles; precision medicine; bioengineering; artificial intelligence; bioinformatics

(This special issue belongs to the Section Molecular Biology)

Chronic Kidney Disease: Novel Advances in Pathophysiology and Therapeutics

edited by

Shihping Hsu

submission deadline 20 Dec 2025 | Viewed by 341 | Submission Open

Keywords: anti-fibrosis; anti-inflammation; biomarker; chronic kidney disease; complement; glucagon-like peptide-1 receptor agonist; immuno modulaton; sodium– glucose cotransporter-2 inhibitor

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Mechanistic and Data-Driven Modelling Approaches for Regulatory Networks and Diseases

edited by

Tianhai Tian

submission deadline 20 Dec 2025 | Viewed by 337 | Submission Open

Keywords: mathematical modelling; data-driven approach; mechanistic and data dual-driven approach; hybrid modelling; machine learning; modelling of regulatory network; inference of molecular regulation; cancer; infection disease; disease intervention

(This special issue belongs to the Section Molecular Informatics)

Abscisic Acid, a New Old Friend to Regulate Abiotic Stress Tolerance in Plants

edited by Marta Marina Pérez-Alonso and

Miguel González-Guzmán

submission deadline 20 Dec 2025 | Viewed by 330 | Submission Open

Keywords: abscisic acid (ABA); ABA perception; ABA signaling network; abiotic stress; hormonal crosstalk; crop species; stress tolerance; plant productivity; agriculture

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Insights into Chronic Liver Disease and Liver Failure

edited by Paolo Gallo

submission deadline 20 Dec 2025 | Viewed by 327 | Submission Open

Keywords: cirrhosis; portal hypertension; liver failure; advanced chronic liver disease; sarcopenia and malnutrition; ascites; medical treatment

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

DNA Methylation in Cancer: Progress and Challenges

edited by

Michael Eccles

submission deadline 20 Dec 2025 | Viewed by 326 | Submission Open

Keywords: DNA methylation; cancer; hypomethylation; hypermethylation; epigenetics; tumor onset; tumor progression; technologies

(This special issue belongs to the Section Molecular Genetics and Genomics)

Physiology and Pathophysiology of Neurodegeneration: New Insights and Advances from Molecular to Cellular Level

edited by

Alessandro Romano

and

Amilcare Barca

submission deadline 20 Dec 2025 | Viewed by 323 | Submission Open

Keywords: central and peripheral nervous systems; neuron homeostasis; neurodegeneration; neurodegenerative disease; neurophysiology; -omic technologies; induced pluripotent stem cell (iPSC); three-dimensional cell culture; organ-on-a-chip (OoC)

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Immunology of Infectious Diseases

edited by

Salvatore Giovanni De Simone

submission deadline 20 Dec 2025 | Viewed by 300 | Submission Open

Keywords: molecular immunology; infectious diseases; innate immunity; adaptive immunity; immunomodulation-based therapies

(This special issue belongs to the Section Molecular Immunology)

Advanced Cell Based Biomaterials for Musculoskeletal Tissue Engineering

edited by

Isabel Calejo

submission deadline 20 Dec 2025 | Viewed by 288 | Submission Open

Keywords: cell-based materials; bioprinting; microfluidics; hydrogels; vascularization; innervation; hierarchical; fiber technologies; microtissues

(This special issue belongs to the Section Materials Science)

Epigenetic and RNA-Based Regulation in Cancer: Mechanism, Therapeutic Targets, and Translational Perspectives

edited by

Moon Nyeo Park

submission deadline 20 Dec 2025 | Viewed by 285 | Submission Open

Keywords: molecular underpinnings of DNA; histone; RNA-based epigenetic regulation; small molecules and epigenetic inhibitors; epigenetic signatures; oncology

(This special issue belongs to the Section Molecular Genetics and Genomics)

Emerging Trends in Adductomics: From Adduct Detection to Environmental Implications

edited by

Mu-Rong Chao

,

Marcus S. Cooke

and

Chiung Wen Hu

submission deadline 20 Dec 2025 | Viewed by 265 | Submission Open

Keywords: adductomics; covalent adducts; crosslinks; biomarkers; electrophilic species; exposome; environmental toxicants; high-resolution tandem mass spectrometry; post-data analysis

(This special issue belongs to the Section Molecular Toxicology)

Immunology and Immunotherapy for Head and Neck Cancer

edited by

Aurora Mirabile

submission deadline 20 Dec 2025 | Viewed by 244 | Submission Open

Keywords: immunotherapy; head and neck cancer; toxicity management; immune system; nutrition; immune therapy and organ failure; mechanisms of immunotherapy resistance

(This special issue belongs to the Section Molecular Immunology)

Advances in Targeted Cancer Therapy and Side-Effect Management

edited by Wei-Min Chang

submission deadline 20 Dec 2025 | Viewed by 239 | Submission Open

Keywords: targeted cancer therapy; novel therapy approaches; personalized treatment; small molecule inhibitors; combination strategies; multi-omics integration; proton therapy; reduced cancer treatment side effects; therapeutic resistance; biomarkers

(This special issue belongs to the Section Molecular Oncology)

Bioactives in Processed Foods: Profiling and Bioavailability Assessment

edited by Cong Wang

submission deadline 20 Dec 2025 | Viewed by 227 | Submission Open

Keywords: food processing; food bioactives; composition; bioavailability; functionality; novel food processing techniques; structure/constituents– bioactivity relationship

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Myosin: Structure, Function and Evolution

edited by Barbara Baryłko and

Joseph P. Albanesi

submission deadline 20 Dec 2025 | Viewed by 223 | Submission Open

Keywords: myosins; actin; molecular motors; organelle trafficking; endocytosis; secretion; membrane tension; RNA transport; force generation; ATPase activity

(This special issue belongs to the Section Macromolecules)

The Role of Ion Channels in Health and Disease

edited by

Joohyun Nam

submission deadline 20 Dec 2025 | Viewed by 223 | Submission Open

Keywords: ion channel; molecular mechanisms; channelopathies; drug discovery; electrophysiology

(This special issue belongs to the Section Molecular Biology)

Advancing Mental Disorder Therapies: Drug Repositioning and Translational Insights from Animal Models

edited by Claudia Bregonzio and Mariela Fernanda Pérez

submission deadline 20 Dec 2025 | Viewed by 204 | Submission Open

Keywords: anxiety; depression; Parkinson's disease; Alzheimer; schizophrenia; neurotransmitter imbalance; novel treatments; new pharmacological targets; preclinical studies

(This special issue belongs to the Section Molecular Neurobiology)

Male Reproduction: Unveiling the Molecular Revolution

edited by

Anthony Archibong

submission deadline 20 Dec 2025 | Viewed by 165 | Submission Open

Keywords: testosterone; spermatogenesis; capacitation; acrosome reaction; endocrine disruptors

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Recent Advances in Molecular Mechanisms of Human Papillomavirus Family (HPV) Induced Oncogenesis, 2nd Edition

edited by

Subhasis B. Biswas

submission deadline 20 Dec 2025 | Viewed by 153 | Submission Open

Keywords: human papillomavirus (HPV); oncogenesis; mechanism; diagnosis; classification; etiology; pathophysiology; biochemistry; genetics; molecular biology; epidemiology; cervical cancer; oropharyngeal cancer; oncology

(This special issue belongs to the Section Molecular Oncology)

Molecular Mechanisms of Pesticide Toxicity and Action

edited by

Fatima Smagulova

submission deadline 20 Dec 2025 | Viewed by 147 | Submission Open

Keywords: neonicotinoids; sex-specific effects; brain– gut– microbiome; endocrine organs; genotoxic effects; epigenetic effects

(This special issue belongs to the Section Molecular Toxicology)

Molecular Aspects of Tumor Radiotherapy

edited by

Johann Matschke

submission deadline 20 Dec 2025 | Viewed by 113 | Submission Open

Keywords: radiotherapy resistance; tumor microenvironment; DNA damage response; metabolic reprogramming; combination therapies

(This special issue belongs to the Section Molecular Oncology)

Redox Physiology

edited by Mateusz Mołoń

submission deadline 21 Dec 2025 | Viewed by 430 | Submission Open

Keywords: redox physiology; reactive oxygen species (ROS); reactive nitrogen species (RNS); oxidative stress; oxidation; redox signaling

(This special issue belongs to the Section Molecular Biology)

Spectroscopic Techniques in Molecular Sciences

edited by

Angela Staicu

submission deadline 25 Dec 2025 | 5 articles | Viewed by 4148 | Submission Open

Keywords: spectroscopy; the structure; dynamics; interactions; and functions of molecules; chemical; biological; pharmaceutical; and materials systems

(This special issue belongs to the Section Molecular Biology)

25th Anniversary of IJMS: Updates and Advances in “Molecular Immunology”

edited by

Julia Kzhyshkowska

submission deadline 25 Dec 2025 | 4 articles | Viewed by 3597 | Submission Open

Keywords: inflammation; innate immunity; adaptive immunity; genetics; epigenetics; immunometabolism; receptors; cytokines; cell therapy; immune checkpoint inhibitors

(This special issue belongs to the Section Molecular Immunology)

Epigenetic Regulation and Molecular Mechanisms in Cardiovascular Diseases

edited by

Paschalis Karakasis

submission deadline 25 Dec 2025 | 1 articles | Viewed by 2548 | Submission Open

Keywords: epigenetic regulation; cardiovascular disease; DNA methylation; histone modifications; non-coding RNAs; vascular inflammation; myocardial remodeling; molecular mechanisms; thera-peutic targets

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular and Genetic Advances in Plant Breeding

edited by Francesca Taranto

submission deadline 25 Dec 2025 | 2 articles | Viewed by 2414 | Submission Open

Keywords: genetic diversity; next-generation sequencing; marker-assisted selection; GWAS/QTL mapping; KASP genotyping; molecular biology TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian // TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back // This page is in English Translate to Simplified Chinese Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh Always translate English to Simplified Chinese Never translate English Never translate admin.mdpi.com

(This special issue belongs to the Section Molecular Plant Sciences)

Skin Cancer: From Molecular Pathophysiology to Novel Treatment

edited by Soon-Hyo Kwon

submission deadline 25 Dec 2025 | 2 articles | Viewed by 2274 | Submission Open

Keywords: basal cell carcinoma; malignant melanoma; molecular genetics; epigenetics; signaling pathways; tumor microenvironment; tumor resistance; biomarkers; molecular target; multiomics; genomics; transcriptomics; proteomics; metabolomics; skin cancer; squamous cell carcinoma

(This special issue belongs to the Section Molecular Oncology)

New Insights into Tryptophan Metabolism

edited by

Katsunori Nonogaki

submission deadline 25 Dec 2025 | Viewed by 360 | Submission Open

Keywords: tryptophan; serotonin; kynurenine; indole; metabolism; IPA; Tph; IDO1; health; disease

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Roots, Transporters, and Signals: Molecular Insights into Plant Mineral Nutrition and Heavy Metals Stress

edited by

Alessio Aprile

submission deadline 25 Dec 2025 | Viewed by 210 | Submission Open

Keywords: plant mineral nutrition; heavy metals; toxic element; transporter; signaling pathway

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Insights in Diabetes

edited by

Mariann Harangi

and

Ferenc Sztanek

submission deadline 25 Dec 2025 | Viewed by 205 | Submission Open

Keywords: insulin signalling pathway; pancreatic beta-cell dysfunction; oxidative stress; epigenetic modifications; metabolic memory; small regulatory RNAs (miRNAs); inflammation and insulin resistance; glucagon-like peptide-1 (GLP-1); glucose-dependent insulinotropic polypeptide (GIP); molecular therapeutic targets; glucose homeostasis regulation

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Emerging Strategy in Bacterial Antibiotic Resistance

edited by Lili Li

submission deadline 28 Dec 2025 | Viewed by 118 | Submission Open

Keywords: fast detection; antimicrobial resistance; virulence; antibacterial action of natural compounds

(This special issue belongs to the Section Molecular Microbiology)

Molecular Investigations in Neurodevelopmental Disorders

edited by Giorgio Medici

submission deadline 30 Dec 2025 | 9 articles | Viewed by 37946 | Submission Open

Keywords: neurodevelopmental disorders; brain; neurons; synapses; molecular research; regulatory networks; molecular pathways; biomarkers; therapies

(This special issue belongs to the Section Molecular Neurobiology)

Recent Research on Hypertension and Related Complications

edited by

Marijn Speeckaert

submission deadline 30 Dec 2025 | 6 articles | Viewed by 28740 | Submission Open

Keywords: arterial hypertension; cardiovascular disease; pathophysiology; molecular mechanisms; complications

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Musculoskeletal Disorders: From Molecular Pathology to Novel Therapeutic Approach

edited by

María Orosia Lucha López

submission deadline 30 Dec 2025 | 10 articles | Viewed by 25538 | Submission Open

Keywords: joints; skeletal muscles; tendons; ligaments; fascia; articular cartilage; intervertebral discs; physiotherapy; novel therapies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms and Treatments in Neurodegenerative Diseases

edited by

Ermanna Turano

and

Raffaella Mariotti

submission deadline 30 Dec 2025 | 7 articles | Viewed by 21847 | Submission Open

Keywords: neurodegenerative diseases; regenerative therapy; neuroprotection; neurodegeneration; pathogenetic mechanisms; cell therapy

(This special issue belongs to the Section Molecular Neurobiology)

Traumatic Brain Injury/Chronic Traumatic Encephalopathy as Cause of Alzheimer’s Disease: Physics and Molecular Biology in the Genesis of Neurodegeneration?

edited by

Dimitrios Kanakis

submission deadline 30 Dec 2025 | 6 articles | Viewed by 21615 | Submission Open

Keywords: traumatic brain injury (TBI); chronic traumatic encephalopathy (CTE); head impacts; Alzheimer's disease (AD）; neurodegeneration

(This special issue belongs to the Section Molecular Neurobiology)

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