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Special Issue "Kinase Signal Transduction 2019"
Deadline for manuscript submissions: closed (31 August 2019).
Laboratory of Health Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, 6-3 Aoba, Aramaki, Aoba-ku, Sendai, Miyagi 980-8578, Japan
Tel. +81-22-795-6827; Fax: +81-22-795-6826
Interests: kinase signal transduction; MAP kinase signaling; stress response; ubiquitination; post-translational modifications; redox signaling; cell death; innate immunity; inflammasome; cancer; drug toxicity
Special Issues and Collections in MDPI journals
This Special Issue is the continuation of our Special Issue “Kinase Signal Transduction 2017” (https://www.mdpi.com/journal/ijms/special_issues/kinase_signal_2017).
Protein kinases phosphorylate a wide variety of substrates, the phosphorylation of which changes their conformation, activity, stability, intracellular localization, and affinity to other molecules. Therefore, protein kinases are critical for various biological functions and cellular processes, such as signal transduction, transcription, protein degradation, vesicle transport, cell growth and death, stress response, immunoregulation, and metabolism. Various types of protein kinases and their regulators have been identified and play a pivotal role in the determination of cell fate. Dysregulation of the protein kinase signal transduction leads to various diseases, including cancer, inflammation, autoimmune disorder, neurodegeneration, heart failure, ischemia, and diabetes, indicating that protein kinases and their regulators are important therapeutic targets for these diseases. Thus, understanding of how protein kinases respond to stimuli and regulate cellular functions is crucial both biologically and clinically. This Special Issue, “Kinase Signal Transduction”, welcomes contributions in all areas of recent and current research associated with novel physiological and pathological functions and regulatory mechanisms of protein kinases, as shown above.
Prof. Dr. Atsushi Matsuzawa
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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