Kinase Signal Transduction 3.0
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".
Deadline for manuscript submissions: closed (30 November 2022) | Viewed by 28112
Special Issue Editor
Interests: kinase signal transduction; MAP kinase signaling; stress response; ubiquitination; post-translational modifications; redox signaling; cell death; innate immunity; inflammasome; cancer; drug toxicity
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Protein kinases phosphorylate a wide variety of substrates, the phosphorylation of which changes their conformation, activity, stability, intracellular localization, and affinity to other molecules. Therefore, protein kinases are critical for various biological functions and cellular processes, such as signal transduction, transcription, protein degradation, vesicle transport, cell growth and death, stress response, immunoregulation, and metabolism. Various types of protein kinases and their regulators have been identified and play a pivotal role in the determination of cell fate. Dysregulation of the protein kinase signal transduction leads to various diseases, including cancer, inflammation, autoimmune disorder, neurodegeneration, heart failure, ischemia, and diabetes, indicating that protein kinases and their regulators are important therapeutic targets for these diseases. Thus, understanding how protein kinases respond to stimuli and regulate cellular functions is crucial both biologically and clinically. This Special Issue, “Kinase Signal Transduction”, welcomes contributions in all areas of recent and current research associated with novel physiological and pathological functions and regulatory mechanisms of protein kinases, as shown above.
Prof. Dr. Atsushi Matsuzawa
Guest Editor
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Keywords
- protein kinase
- phosphorylation signal
- transduciton signaling
- pathway cellular response
- MAP kinase cascade protein
- phosphatase signaling
- complex signalosome signaling system
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Related Special Issues
- Kinase Signal Transduction in International Journal of Molecular Sciences (18 articles)
- Kinase Signal Transduction 2017 in International Journal of Molecular Sciences (13 articles)
- Kinase Signal Transduction 1.0 in International Journal of Molecular Sciences (30 articles)
- Kinase Signal Transduction 2.0 in International Journal of Molecular Sciences (36 articles)
- Kinase Signal Transduction 4.0 in International Journal of Molecular Sciences (4 articles)