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arrow_forward_ios Current issue - Vol. 27 (2026)
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Announcements
3 April 2026
Colorectal Cancer Awareness Month–March 2026
As part of its ongoing commitment to advancing cancer research and knowledge exchange, MDPI highlights colorectal cancer in the March edition—one of the most prevalent and deadly cancers worldwide. It ranks as the third most diagnosed cancer and the second leading cause of cancer-related deaths globally, with an estimated 1.9 million new cases and over 900,000 deaths each year.
Of growing concern is the steady rise in incidence among individuals under 50, a trend observed over the past two to three decades. This underscores the urgent need to better understand underlying risk factors, strengthen early detection strategies, and develop innovative diagnostic tools.
Through curated research, Special Issues, and expert-led webinars, MDPI journals continue to support collaboration across researchers, clinicians, and policymakers. Such collective efforts are essential to accelerate discoveries and translate them into meaningful action—advancing toward more effective prevention, earlier detection, and improved patient outcomes.

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| Keynote Speakers | |||
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| Prof. Dr. Paola Patrignani, “G. d’Annunzio” University School of Medicine, Italy |
Prof. Dr. William Gmeiner, Wake Forest University, USA |
Dr. Eva Martínez-Balibrea, |
Dr. Zoltán Wiener, Semmelweis University, Hungary |
Register for this webinar for free here!

“Integrative Mechanistic Investigation of the Anticancer Effects of Panax notoginseng in Colorectal Cancer”
by Jaemoo Chun, Sarah Shin and Jeeyoun Jung
Molecules 2026, 31(5), 807; https://doi.org/10.3390/molecules31050807
“Integrated Multi-Omics Analysis Identifies Novel Prognostic and Diagnostic Hub Genes in Colorectal Cancer”
by Devi Lal and Himani Pandey
Onco 2025, 5(4), 50; https://doi.org/10.3390/onco5040050
“A Multimodal MRI-Based Model for Colorectal Liver Metastasis Prediction: Integrating Radiomics, Deep Learning, and Clinical Features with SHAP Interpretation”
by Xin Yan, Furui Duan, Lu Chen, Runhong Wang, Kexin Li, Qiao Sun and Kuang Fuby Xin Yan, Furui Duan, Lu Chen, Runhong Wang, Kexin Li, Qiao Sun and Kuang Fu
Curr. Oncol. 2025, 32(8), 431; https://doi.org/10.3390/curroncol32080431
“Exploring Experimental Models of Colorectal Cancer: A Critical Appraisal from 2D Cell Systems to Organoids, Humanized Mouse Avatars, Organ-on-Chip, CRISPR Engineering, and AI-Driven Platforms—Challenges and Opportunities for Translational Precision Oncology”
by Ahad Al-Kabani, Bintul Huda, Jewel Haddad, Maryam Yousuf, Farida Bhurka, Faika Ajaz, Rajashree Patnaik, Shirin Jannati and Yajnavalka Banerjee
Cancers 2025, 17(13), 2163; https://doi.org/10.3390/cancers17132163
“The Gut Microbiota and Colorectal Cancer: Understanding the Link and Exploring Therapeutic Interventions”
by Imen Zalila-Kolsi, Dhoha Dhieb, Hussam A. Osman and Hadjer Mekideche
Biology 2025, 14(3), 251; https://doi.org/10.3390/biology14030251
“A Novel Bacteriophage with the Potential to Inhibit Fusobacterium nucleatum-Induced Proliferation of Colorectal Cancer Cells”
by Ho Yin Pekkle Lam, Meng-Jiun Lai, Pin-Chun Wang, Wen-Jui Wu, Li-Kuang Chen, Hsiang-Wei Fan, Chun-Chieh Tseng, Shih-Yi Peng and Kai-Chih Chang
Antibiotics 2025, 14(1), 45; https://doi.org/10.3390/antibiotics14010045
“A New Blood-Based Epigenetic Diagnostic Biomarker Test (EpiSwitch®® NST) with High Sensitivity and Positive Predictive Value for Colorectal Cancer and Precancerous Polyps”
by Ewan Hunter, Heba Alshaker, Cicely Weston, Mutaz Issa, Shekinah Bautista, Abel Gebregzabhar, Anya Virdi, Ann Dring, Ryan Powell, Jayne Green et al.
Cancers 2025, 17(3), 521; https://doi.org/10.3390/cancers17030521
“The Role of KRAS Mutations in Colorectal Cancer: Biological Insights, Clinical Implications, and Future Therapeutic Perspectives”
by Mitsunobu Takeda, Shoma Yoshida, Takuya Inoue, Yuki Sekido, Tsuyoshi Hata, Atsushi Hamabe, Takayuki Ogino, Norikatsu Miyoshi, Mamoru Uemura, Hirofumi Yamamoto, Yuichiro Doki and Hidetoshi Eguchi
Cancers 2025, 17(3), 428; https://doi.org/10.3390/cancers17030428
“Network Pharmacology and Bioinformatics Study of Six Medicinal Food Homologous Plants Against Colorectal Cancer”
by Xinyue Zhao, Jian Xiu, Hengzheng Yang, Weiwei Han and Yue Jin
Int. J. Mol. Sci. 2025, 26(3), 930; https://doi.org/10.3390/ijms26030930
“A Review of Potential Agents for Colon Cancer Interception in FAP Patients: Evidence from Preclinical Studies in APCMin/+ Mice”
by Karthikkumar Venkatachalam, Krishnendu Goswami, Venkateshwar Madka and Chinthalapally V. Rao
Targets 2025, 3(1), 4; https://doi.org/10.3390/targets3010004
“Colorectal Cancer: Epidemiology, Risk Factors, and Prevention”
by Gholamreza Roshandel, Fatemeh Ghasemi-Kebria and Reza Malekzadeh
Cancers 2024, 16(8), 1530; https://doi.org/10.3390/cancers16081530
“Symptom Burden and Time from Symptom Onset to Cancer Diagnosis in Patients with Early-Onset Colorectal Cancer: A Multicenter Retrospective Analysis”
by Victoria A. Baronas, Arif A. Arif, Eric Bhang, Gale K. Ladua, Carl J. Brown, Fergal Donnellan, Sharlene Gill, Heather C. Stuart and Jonathan M. Loree
Curr. Oncol. 2024, 31(4), 2133-2144; https://doi.org/10.3390/curroncol31040158

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“Recent Advances in Surgical Strategies for Managing Metastatic Colorectal Cancer” |
“Novel Strategies in the Prevention/Treatment of Colorectal Cancer: 2nd Edition” |
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“Molecular Mechanisms and Therapeutic Strategies of Colorectal Cancer” |
“Gut Microbiota and Inflammation in Colorectal Tumor Development and Progression” |
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